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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-141 Sentence denotes A novel compound, maltolyl p-coumarate, attenuates cognitive deficits and shows neuroprotective effects in vitro and in vivo dementia models.
T2 142-333 Sentence denotes To develop a novel and effective drug that could enhance cognitive function and neuroprotection, we newly synthesized maltolyl p-coumarate by the esterification of maltol and p-coumaric acid.
T3 334-509 Sentence denotes In the present study, we investigated whether maltolyl p-coumarate could improve cognitive decline in scopolamine-injected rats and in amyloid beta peptide(1-42)-infused rats.
T4 510-731 Sentence denotes Maltolyl p-coumarate was found to attenuate cognitive deficits in both rat models using passive avoidance test and to reduce apoptotic cell death observed in the hippocampus of the amyloid beta peptide(1-42)-infused rats.
T5 732-830 Sentence denotes We also examined the neuroprotective effects of maltolyl p-coumarate in vitro using SH-SY5Y cells.
T6 831-944 Sentence denotes Cells were pretreated with maltolyl p-coumarate, before exposed to amyloid beta peptide(1-42), glutamate or H2O2.
T7 945-1109 Sentence denotes We found that maltolyl p-coumarate significantly decreased apoptotic cell death and reduced reactive oxygen species, cytochrome c release, and caspase 3 activation.
T8 1110-1370 Sentence denotes Taking these in vitro and in vivo results together, our study suggests that maltolyl p-coumarate is a potentially effective candidate against Alzheimer's disease that is characterized by wide spread neuronal death and progressive decline of cognitive function.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 457-461 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114
T4 504-508 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114
T7 581-584 OrganismTaxon denotes rat NCBItxid:10116|NCBItxid:10114
T9 672-683 OrganismTaxon denotes hippocampus NCBItxid:72046
T10 726-730 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
4203 18-38 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4204 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits MESH:D003072
4205 125-133 DiseaseOrPhenotypicFeature denotes dementia MESH:D003704
4206 260-280 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4207 306-312 ChemicalEntity denotes maltol MESH:C008316
4208 317-332 ChemicalEntity denotes p-coumaric acid MESH:C495469
4209 380-400 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4210 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline MESH:D003072
4211 436-447 ChemicalEntity denotes scopolamine MESH:D012601
4212 457-461 OrganismTaxon denotes rats NCBITaxon:10116
4213 469-495 ChemicalEntity denotes amyloid beta peptide(1-42) MESH:C544092
4214 504-508 OrganismTaxon denotes rats NCBITaxon:10116
4215 510-530 ChemicalEntity denotes Maltolyl p-coumarate MESH:C524754
4216 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits MESH:D003072
4217 581-584 OrganismTaxon denotes rat NCBITaxon:10116
4218 691-717 ChemicalEntity denotes amyloid beta peptide(1-42) MESH:C544092
4219 726-730 OrganismTaxon denotes rats NCBITaxon:10116
4220 780-800 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4221 816-823 CellLine denotes SH-SY5Y NCBITaxon:9606
4222 858-878 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4223 898-924 ChemicalEntity denotes amyloid beta peptide(1-42) MESH:C544092
4224 926-935 ChemicalEntity denotes glutamate MESH:D018698
4225 939-943 ChemicalEntity denotes H2O2 MESH:D006861
4226 959-979 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4227 1037-1060 ChemicalEntity denotes reactive oxygen species MESH:D017382
4228 1062-1074 ChemicalEntity denotes cytochrome c MESH:D045304
4229 1088-1097 GeneOrGeneProduct denotes caspase 3 NCBIGene:25402
4230 1186-1206 ChemicalEntity denotes maltolyl p-coumarate MESH:C524754
4231 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease MESH:D000544
4232 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death MESH:D009410
4233 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function MESH:D003072

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 125-133 DiseaseOrPhenotypicFeature denotes dementia 0001627
T2 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease 0004975
T3 1309-1317 DiseaseOrPhenotypicFeature denotes neuronal 0004466

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 2-7 GeneOrGeneProduct denotes novel
T2 155-160 GeneOrGeneProduct denotes novel
T3 328-332 GeneOrGeneProduct denotes acid
T4 477-481 GeneOrGeneProduct denotes beta
T5 645-649 GeneOrGeneProduct denotes cell
T6 699-703 GeneOrGeneProduct denotes beta
T7 906-910 GeneOrGeneProduct denotes beta
T8 926-935 GeneOrGeneProduct denotes glutamate
T9 1014-1018 GeneOrGeneProduct denotes cell
T10 1029-1036 GeneOrGeneProduct denotes reduced
T11 1062-1074 GeneOrGeneProduct denotes cytochrome c
T12 1088-1097 GeneOrGeneProduct denotes caspase 3

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 2-7 GeneOrGeneProduct denotes novel
T2 40-50 GeneOrGeneProduct denotes attenuates
T3 155-160 GeneOrGeneProduct denotes novel
T4 328-332 GeneOrGeneProduct denotes acid
T5 477-481 GeneOrGeneProduct denotes beta
T6 544-553 GeneOrGeneProduct denotes attenuate
T7 616-620 GeneOrGeneProduct denotes test
T8 628-634 GeneOrGeneProduct denotes reduce
T9 645-649 GeneOrGeneProduct denotes cell
T10 699-703 GeneOrGeneProduct denotes beta
T11 824-829 GeneOrGeneProduct denotes cells
T12 831-836 GeneOrGeneProduct denotes Cells
T13 906-910 GeneOrGeneProduct denotes beta
T14 926-935 GeneOrGeneProduct denotes glutamate
T15 1014-1018 GeneOrGeneProduct denotes cell
T16 1029-1036 GeneOrGeneProduct denotes reduced
T17 1062-1074 GeneOrGeneProduct denotes cytochrome c
T18 1088-1097 GeneOrGeneProduct denotes caspase 3
T19 1098-1108 GeneOrGeneProduct denotes activation

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T2 125-133 DiseaseOrPhenotypicFeature denotes dementia D003704
T3 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline D060825
T4 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T5 650-655 DiseaseOrPhenotypicFeature denotes death D003643
T6 1019-1024 DiseaseOrPhenotypicFeature denotes death D003643
T7 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease D000544
T8 1318-1323 DiseaseOrPhenotypicFeature denotes death D003643
T9 1340-1360 DiseaseOrPhenotypicFeature denotes decline of cognitive D060825

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 926-935 GeneOrGeneProduct denotes glutamate
T2 1062-1074 GeneOrGeneProduct denotes cytochrome c
T3 1088-1097 GeneOrGeneProduct denotes caspase 3

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 125-133 DiseaseOrPhenotypicFeature denotes dementia 0001627
T2 469-476 DiseaseOrPhenotypicFeature denotes amyloid 0019065
T3 691-698 DiseaseOrPhenotypicFeature denotes amyloid 0019065
T4 898-905 DiseaseOrPhenotypicFeature denotes amyloid 0019065
T5 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease 0004975

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T2 125-133 DiseaseOrPhenotypicFeature denotes dementia D003704
T3 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline D060825
T4 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T5 650-655 DiseaseOrPhenotypicFeature denotes death D003643
T6 1019-1024 DiseaseOrPhenotypicFeature denotes death D003643
T7 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease D000544
T8 1318-1323 DiseaseOrPhenotypicFeature denotes death D003643
T9 1340-1360 DiseaseOrPhenotypicFeature denotes decline of cognitive D060825

LitCoin_CellLine

Id Subject Object Predicate Lexical cue cellosaurus_accession_id
T1 816-823 CellLine denotes SH-SY5Y CVCL_0019

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T2 125-133 DiseaseOrPhenotypicFeature denotes dementia D003704
T3 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline D060825
T4 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T5 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease D000544
T6 1340-1360 DiseaseOrPhenotypicFeature denotes decline of cognitive D060825

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate C524754
T2 260-280 ChemicalEntity denotes maltolyl p-coumarate C524754
T3 306-312 ChemicalEntity denotes maltol C008316
T4 317-332 ChemicalEntity denotes p-coumaric acid C495469|http://purl.obolibrary.org/obo/CHEBI_36090
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate C524754
T7 436-447 ChemicalEntity denotes scopolamine D012601|http://purl.obolibrary.org/obo/CHEBI_16794
T9 469-481 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T10 510-530 ChemicalEntity denotes Maltolyl p-coumarate C524754
T11 691-703 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T12 780-800 ChemicalEntity denotes maltolyl p-coumarate C524754
T13 858-878 ChemicalEntity denotes maltolyl p-coumarate C524754
T14 898-910 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T15 926-935 ChemicalEntity denotes glutamate http://purl.obolibrary.org/obo/CHEBI_29987|http://purl.obolibrary.org/obo/CHEBI_14321
T17 939-943 ChemicalEntity denotes H2O2 http://purl.obolibrary.org/obo/CHEBI_16240
T18 959-979 ChemicalEntity denotes maltolyl p-coumarate C524754
T19 1037-1060 ChemicalEntity denotes reactive oxygen species D017382|http://purl.obolibrary.org/obo/CHEBI_26523
T21 1062-1074 ChemicalEntity denotes cytochrome c http://purl.obolibrary.org/obo/CHEBI_18070
T22 1186-1206 ChemicalEntity denotes maltolyl p-coumarate C524754

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 457-461 OrganismTaxon denotes rats
T2 504-508 OrganismTaxon denotes rats
T3 581-584 OrganismTaxon denotes rat
T4 726-730 OrganismTaxon denotes rats

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID: cellosaurus_accession_id
T1 816-823 CellLine denotes SH-SY5Y CVCL_0019
T22 1186-1206 ChemicalEntity denotes maltolyl p-coumarate C524754
T18 959-979 ChemicalEntity denotes maltolyl p-coumarate C524754
T21 1062-1074 ChemicalEntity denotes cytochrome c http://purl.obolibrary.org/obo/CHEBI_18070
T19 1037-1060 ChemicalEntity denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523|D017382
T17 939-943 ChemicalEntity denotes H2O2 http://purl.obolibrary.org/obo/CHEBI_16240
T15 926-935 ChemicalEntity denotes glutamate http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987
T14 898-910 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T13 858-878 ChemicalEntity denotes maltolyl p-coumarate C524754
T12 780-800 ChemicalEntity denotes maltolyl p-coumarate C524754
T11 691-703 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T10 510-530 ChemicalEntity denotes Maltolyl p-coumarate C524754
T9 469-481 ChemicalEntity denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T7 436-447 ChemicalEntity denotes scopolamine http://purl.obolibrary.org/obo/CHEBI_16794|D012601
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate C524754
T4 317-332 ChemicalEntity denotes p-coumaric acid http://purl.obolibrary.org/obo/CHEBI_36090|C495469
T3 306-312 ChemicalEntity denotes maltol C008316
T2 260-280 ChemicalEntity denotes maltolyl p-coumarate C524754
T9285 18-38 ChemicalEntity denotes maltolyl p-coumarate C524754
T90531 1088-1097 GeneOrGeneProduct denotes caspase 3
T4941 1062-1074 GeneOrGeneProduct denotes cytochrome c
T68454 926-935 GeneOrGeneProduct denotes glutamate
T2815 1340-1360 DiseaseOrPhenotypicFeature denotes decline of cognitive D060825
T5 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease D000544
T93500 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T9701 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline D060825
T42528 125-133 DiseaseOrPhenotypicFeature denotes dementia D003704
T76176 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits DISEASE
T72848 726-730 OrganismTaxon denotes rats
T37991 581-584 OrganismTaxon denotes rat
T89601 504-508 OrganismTaxon denotes rats
T75844 457-461 OrganismTaxon denotes rats

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 415-432 HP_0001268 denotes cognitive decline
T2 469-476 HP_0011034 denotes amyloid
T3 554-572 HP_0100543 denotes cognitive deficits
T4 691-698 HP_0011034 denotes amyloid
T5 898-905 HP_0011034 denotes amyloid
T6 1252-1271 HP_0002511 denotes Alzheimer's disease
T7 1328-1360 HP_0001268 denotes progressive decline of cognitive
T8 1340-1360 HP_0001268 denotes decline of cognitive

biored-valid-deepseek-nr-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 260-266 ChemicalEntity denotes maltol
T3 317-332 ChemicalEntity denotes p-coumaric acid
T4 380-400 ChemicalEntity denotes maltolyl p-coumarate
T5 436-447 ChemicalEntity denotes scopolamine
T6 780-800 ChemicalEntity denotes maltolyl p-coumarate
T7 816-829 CellLine denotes SH-SY5Y cells
T8 858-878 ChemicalEntity denotes maltolyl p-coumarate
T9 926-935 ChemicalEntity denotes glutamate
T10 939-943 ChemicalEntity denotes H2O2
T11 1062-1074 GeneOrGeneProduct denotes cytochrome c
T12 1088-1097 GeneOrGeneProduct denotes caspase 3
T13 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease

biored-valid

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 306-312 ChemicalEntity denotes maltol
T6 317-332 ChemicalEntity denotes p-coumaric acid
T7 380-400 ChemicalEntity denotes maltolyl p-coumarate
T8 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T9 436-447 ChemicalEntity denotes scopolamine
T10 457-461 OrganismTaxon denotes rats
T11 469-495 ChemicalEntity denotes amyloid beta peptide(1-42)
T12 504-508 OrganismTaxon denotes rats
T13 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T14 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T15 581-584 OrganismTaxon denotes rat
T16 691-717 ChemicalEntity denotes amyloid beta peptide(1-42)
T17 726-730 OrganismTaxon denotes rats
T18 780-800 ChemicalEntity denotes maltolyl p-coumarate
T19 816-823 CellLine denotes SH-SY5Y
T20 858-878 ChemicalEntity denotes maltolyl p-coumarate
T21 898-924 ChemicalEntity denotes amyloid beta peptide(1-42)
T22 926-935 ChemicalEntity denotes glutamate
T23 939-943 ChemicalEntity denotes H2O2
T24 959-979 ChemicalEntity denotes maltolyl p-coumarate
T25 1037-1060 ChemicalEntity denotes reactive oxygen species
T26 1062-1074 ChemicalEntity denotes cytochrome c
T27 1088-1097 GeneOrGeneProduct denotes caspase 3
T28 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T29 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T30 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T31 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function

biored-valid-deepseek-nr-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 260-280 ChemicalEntity denotes maltolyl p-coumarate
T3 317-332 ChemicalEntity denotes p-coumaric acid
T4 380-400 ChemicalEntity denotes maltolyl p-coumarate
T5 436-447 ChemicalEntity denotes scopolamine
T6 469-489 ChemicalEntity denotes amyloid beta peptide
T7 489-495 SequenceVariant denotes (1-42)
T8 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T9 780-800 ChemicalEntity denotes maltolyl p-coumarate
T10 926-935 ChemicalEntity denotes glutamate
T11 939-943 ChemicalEntity denotes H2O2
T12 1062-1074 GeneOrGeneProduct denotes cytochrome c
T13 1088-1097 GeneOrGeneProduct denotes caspase 3
T14 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease

biored-valid-deepseek-r-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-140 DiseaseOrPhenotypicFeature denotes dementia models
T4 260-266 ChemicalEntity denotes maltol
T5 276-279 OrganismTaxon denotes rat
T6 317-332 ChemicalEntity denotes p-coumaric acid
T7 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T8 436-447 ChemicalEntity denotes scopolamine
T9 457-461 OrganismTaxon denotes rats
T10 469-495 ChemicalEntity denotes amyloid beta peptide(1-42)
T11 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T12 816-829 CellLine denotes SH-SY5Y cells
T13 926-935 ChemicalEntity denotes glutamate
T14 939-943 ChemicalEntity denotes H2O2
T15 1037-1060 ChemicalEntity denotes reactive oxygen species
T16 1062-1074 GeneOrGeneProduct denotes cytochrome c
T17 1088-1097 GeneOrGeneProduct denotes caspase 3
T18 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease

biored-valid-deepseek-r-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-266 ChemicalEntity denotes maltol
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T7 436-447 ChemicalEntity denotes scopolamine
T8 457-461 OrganismTaxon denotes rats
T9 469-495 SequenceVariant denotes amyloid beta peptide(1-42)
T10 816-829 CellLine denotes SH-SY5Y cells
T11 926-935 ChemicalEntity denotes glutamate
T12 939-943 ChemicalEntity denotes H2O2
T13 1037-1060 ChemicalEntity denotes reactive oxygen species
T14 1062-1074 GeneOrGeneProduct denotes cytochrome c
T15 1088-1097 GeneOrGeneProduct denotes caspase 3
T16 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T17 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T18 1328-1369 DiseaseOrPhenotypicFeature denotes progressive decline of cognitive function

biored-valid-gemini-nr-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate
T7 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T8 436-447 ChemicalEntity denotes scopolamine
T9 457-461 OrganismTaxon denotes rats
T10 469-495 ChemicalEntity denotes amyloid beta peptide(1-42)
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T14 691-717 ChemicalEntity denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-823 CellLine denotes SH-SY5Y
T18 898-924 ChemicalEntity denotes amyloid beta peptide(1-42)
T19 926-935 ChemicalEntity denotes glutamate
T20 939-943 ChemicalEntity denotes H2O2
T21 959-979 ChemicalEntity denotes maltolyl p-coumarate
T22 1004-1024 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T23 1037-1060 ChemicalEntity denotes reactive oxygen species
T24 1062-1074 GeneOrGeneProduct denotes cytochrome c
T25 1088-1097 GeneOrGeneProduct denotes caspase 3
T26 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T27 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T28 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T29 1328-1369 DiseaseOrPhenotypicFeature denotes progressive decline of cognitive function

biored-valid-gemini-r-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 80-103 DiseaseOrPhenotypicFeature denotes neuroprotective effects
T4 125-133 DiseaseOrPhenotypicFeature denotes dementia
T5 199-217 DiseaseOrPhenotypicFeature denotes cognitive function
T6 222-237 DiseaseOrPhenotypicFeature denotes neuroprotection
T7 260-280 ChemicalEntity denotes maltolyl p-coumarate
T8 317-332 ChemicalEntity denotes p-coumaric acid
T9 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T10 436-447 ChemicalEntity denotes scopolamine
T11 457-461 OrganismTaxon denotes rats
T12 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T13 504-508 OrganismTaxon denotes rats
T14 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T15 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T16 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T17 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T18 753-776 DiseaseOrPhenotypicFeature denotes neuroprotective effects
T19 780-800 ChemicalEntity denotes maltolyl p-coumarate
T20 816-829 CellLine denotes SH-SY5Y cells
T21 858-878 ChemicalEntity denotes maltolyl p-coumarate
T22 926-935 ChemicalEntity denotes glutamate
T23 939-943 ChemicalEntity denotes H2O2
T24 1037-1060 ChemicalEntity denotes reactive oxygen species
T25 1062-1074 GeneOrGeneProduct denotes cytochrome c
T26 1088-1097 GeneOrGeneProduct denotes caspase 3
T27 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T28 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T29 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function

biored-valid-gemini-r-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T7 436-447 ChemicalEntity denotes scopolamine
T8 457-461 OrganismTaxon denotes rats
T9 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T10 504-508 OrganismTaxon denotes rats
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T14 780-800 ChemicalEntity denotes maltolyl p-coumarate
T15 816-823 CellLine denotes SH-SY5Y
T16 858-878 ChemicalEntity denotes maltolyl p-coumarate
T17 926-935 ChemicalEntity denotes glutamate
T18 939-943 ChemicalEntity denotes H2O2
T19 1062-1074 GeneOrGeneProduct denotes cytochrome c
T20 1088-1097 GeneOrGeneProduct denotes caspase 3
T21 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T22 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T23 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function

biored-valid-gpt-nr-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate
T7 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T8 436-447 ChemicalEntity denotes scopolamine
T9 457-461 OrganismTaxon denotes rats
T10 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 581-584 OrganismTaxon denotes rat
T13 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T14 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-823 CellLine denotes SH-SY5Y
T18 858-878 ChemicalEntity denotes maltolyl p-coumarate
T19 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T20 926-935 ChemicalEntity denotes glutamate
T21 939-943 ChemicalEntity denotes H2O2
T22 959-979 ChemicalEntity denotes maltolyl p-coumarate
T23 1004-1024 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T24 1062-1074 GeneOrGeneProduct denotes cytochrome c
T25 1088-1097 GeneOrGeneProduct denotes caspase 3
T26 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T27 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T28 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death

biored-valid-gpt-r-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 125-133 DiseaseOrPhenotypicFeature denotes dementia
T3 260-280 ChemicalEntity denotes maltolyl p-coumarate
T4 317-332 ChemicalEntity denotes p-coumaric acid
T5 380-400 ChemicalEntity denotes maltolyl p-coumarate
T6 436-447 ChemicalEntity denotes scopolamine
T7 457-461 OrganismTaxon denotes rats
T8 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T9 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T10 581-584 OrganismTaxon denotes rat
T11 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T12 726-730 OrganismTaxon denotes rats
T13 780-800 ChemicalEntity denotes maltolyl p-coumarate
T14 816-823 CellLine denotes SH-SY5Y
T15 858-878 ChemicalEntity denotes maltolyl p-coumarate
T16 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T17 926-935 ChemicalEntity denotes glutamate
T18 939-943 ChemicalEntity denotes H2O2
T19 959-979 ChemicalEntity denotes maltolyl p-coumarate
T20 1062-1074 GeneOrGeneProduct denotes cytochrome c
T21 1088-1097 GeneOrGeneProduct denotes caspase 3
T22 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T23 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease

biored-valid-gpt-nr-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate
T7 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T8 436-447 ChemicalEntity denotes scopolamine
T9 457-461 OrganismTaxon denotes rats
T10 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 581-584 OrganismTaxon denotes rat
T14 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-823 CellLine denotes SH-SY5Y
T18 858-878 ChemicalEntity denotes maltolyl p-coumarate
T19 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T20 926-935 ChemicalEntity denotes glutamate
T21 939-943 ChemicalEntity denotes H2O2
T22 959-979 ChemicalEntity denotes maltolyl p-coumarate
T23 1062-1074 GeneOrGeneProduct denotes cytochrome c
T24 1088-1097 GeneOrGeneProduct denotes caspase 3
T25 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T26 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease

biored-valid-gpt-r-ng

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 306-312 ChemicalEntity denotes maltol
T6 317-332 ChemicalEntity denotes p-coumaric acid
T7 380-400 ChemicalEntity denotes maltolyl p-coumarate
T8 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T9 436-447 ChemicalEntity denotes scopolamine
T10 457-461 OrganismTaxon denotes rats
T11 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T12 504-508 OrganismTaxon denotes rats
T13 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T14 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T15 581-584 OrganismTaxon denotes rat
T16 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T17 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T18 726-730 OrganismTaxon denotes rats
T19 780-800 ChemicalEntity denotes maltolyl p-coumarate
T20 816-823 CellLine denotes SH-SY5Y
T21 858-878 ChemicalEntity denotes maltolyl p-coumarate
T22 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T23 926-935 ChemicalEntity denotes glutamate
T24 939-943 ChemicalEntity denotes H2O2
T25 959-979 ChemicalEntity denotes maltolyl p-coumarate
T26 1004-1024 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T27 1037-1060 ChemicalEntity denotes reactive oxygen species
T28 1062-1074 GeneOrGeneProduct denotes cytochrome c
T29 1088-1097 GeneOrGeneProduct denotes caspase 3
T30 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T31 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T32 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T33 1328-1369 DiseaseOrPhenotypicFeature denotes progressive decline of cognitive function

biored-valid-gemini-nr-g

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T7 436-447 ChemicalEntity denotes scopolamine
T8 457-461 OrganismTaxon denotes rats
T9 469-495 ChemicalEntity denotes amyloid beta peptide(1-42)
T10 504-507 OrganismTaxon denotes rat
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T14 691-717 ChemicalEntity denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-823 CellLine denotes SH-SY5Y
T18 858-878 ChemicalEntity denotes maltolyl p-coumarate
T19 898-924 ChemicalEntity denotes amyloid beta peptide(1-42)
T20 926-935 ChemicalEntity denotes glutamate
T21 939-943 ChemicalEntity denotes H2O2
T22 959-979 ChemicalEntity denotes maltolyl p-coumarate
T23 1004-1024 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T24 1037-1060 ChemicalEntity denotes reactive oxygen species
T25 1062-1074 GeneOrGeneProduct denotes cytochrome c
T26 1088-1097 GeneOrGeneProduct denotes caspase 3
T27 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T28 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T29 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function

biored-valid-gpt-r-m

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 380-400 ChemicalEntity denotes maltolyl p-coumarate
T7 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T8 436-447 ChemicalEntity denotes scopolamine
T9 457-461 OrganismTaxon denotes rats
T10 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 581-584 OrganismTaxon denotes rat
T14 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-829 CellLine denotes SH-SY5Y cells
T18 858-878 ChemicalEntity denotes maltolyl p-coumarate
T19 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T20 926-935 ChemicalEntity denotes glutamate
T21 939-943 ChemicalEntity denotes H2O2
T22 959-979 ChemicalEntity denotes maltolyl p-coumarate
T23 1062-1074 GeneOrGeneProduct denotes cytochrome c
T24 1088-1097 GeneOrGeneProduct denotes caspase 3
T25 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T26 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T27 1328-1369 DiseaseOrPhenotypicFeature denotes progressive decline of cognitive function

biored-valid-gemini-r-m

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-280 ChemicalEntity denotes maltolyl p-coumarate
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T7 436-447 ChemicalEntity denotes scopolamine
T8 457-461 OrganismTaxon denotes rats
T9 469-495 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T10 504-507 OrganismTaxon denotes rat
T11 510-530 ChemicalEntity denotes Maltolyl p-coumarate
T12 554-572 DiseaseOrPhenotypicFeature denotes cognitive deficits
T13 635-655 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T14 691-717 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T15 726-730 OrganismTaxon denotes rats
T16 780-800 ChemicalEntity denotes maltolyl p-coumarate
T17 816-829 CellLine denotes SH-SY5Y cells
T18 858-878 ChemicalEntity denotes maltolyl p-coumarate
T19 898-924 GeneOrGeneProduct denotes amyloid beta peptide(1-42)
T20 926-935 ChemicalEntity denotes glutamate
T21 939-943 ChemicalEntity denotes H2O2
T22 1004-1024 DiseaseOrPhenotypicFeature denotes apoptotic cell death
T23 1037-1060 ChemicalEntity denotes reactive oxygen species
T24 1062-1074 GeneOrGeneProduct denotes cytochrome c
T25 1088-1097 GeneOrGeneProduct denotes caspase 3
T26 1186-1206 ChemicalEntity denotes maltolyl p-coumarate
T27 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease
T28 1309-1323 DiseaseOrPhenotypicFeature denotes neuronal death
T29 1340-1369 DiseaseOrPhenotypicFeature denotes decline of cognitive function

biored-valid-deepseek-r-m

Id Subject Object Predicate Lexical cue
T1 18-38 ChemicalEntity denotes maltolyl p-coumarate
T2 51-69 DiseaseOrPhenotypicFeature denotes cognitive deficits
T3 125-133 DiseaseOrPhenotypicFeature denotes dementia
T4 260-266 ChemicalEntity denotes maltol
T5 317-332 ChemicalEntity denotes p-coumaric acid
T6 415-432 DiseaseOrPhenotypicFeature denotes cognitive decline
T7 436-447 ChemicalEntity denotes scopolamine
T8 457-461 OrganismTaxon denotes rats
T9 469-495 ChemicalEntity denotes amyloid beta peptide(1-42)
T10 581-584 OrganismTaxon denotes rat
T11 816-829 CellLine denotes SH-SY5Y cells
T12 926-935 ChemicalEntity denotes glutamate
T13 939-943 ChemicalEntity denotes H2O2
T14 1062-1074 GeneOrGeneProduct denotes cytochrome c
T15 1088-1097 GeneOrGeneProduct denotes caspase 3
T16 1252-1271 DiseaseOrPhenotypicFeature denotes Alzheimer's disease