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GlyCosmos6-Glycan-Motif-Image

Id	Subject	Object	Predicate	Lexical cue	image
T1	790-797	Glycan_Motif	denotes	heparin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T3	987-994	Glycan_Motif	denotes	Heparin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T5	1028-1035	Glycan_Motif	denotes	heparin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T7	1146-1153	Glycan_Motif	denotes	heparin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T9	1157-1164	Glycan_Motif	denotes	heparin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T11	1182-1193	Glycan_Motif	denotes	chondroitin	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT

Glycosmos6-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glyco_epitope_db_id
T1	19-34	GlycoEpitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T2	549-564	GlycoEpitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T3	1182-1193	GlycoEpitope	denotes	chondroitin	http://www.glycoepitope.jp/epitopes/EP0081
T4	1626-1641	GlycoEpitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-169	Sentence	denotes	Potential role for heparan sulfate proteoglycans in regulation of transforming growth factor-beta (TGF-beta) by modulating assembly of latent TGF-beta-binding protein-1.
T2	170-373	Sentence	denotes	Latent transforming growth factor-beta-binding proteins (LTBPs) are extracellular matrix (ECM) glycoproteins that play a major role in storage of latent TGF-beta in the ECM and regulate its availability.
T3	374-518	Sentence	denotes	We have previously identified fibronectin as a key molecule for incorporation of LTBP1 and TGF-beta into the ECM of osteoblasts and fibroblasts.
T4	519-629	Sentence	denotes	Here we provide evidence that heparan sulfate proteoglycans may mediate binding between LTBP1 and fibronectin.
T5	630-868	Sentence	denotes	We have localized critical domains in the N terminus of LTBP1 that are required for co-localization with fibronectin in osteoblast cultures and have identified heparin binding sites in the N terminus of LTBP1 between residues 345 and 487.
T6	869-986	Sentence	denotes	Solid-phase binding assays suggest that LTBP1 does not bind directly to fibronectin but that the binding is indirect.
T7	987-1099	Sentence	denotes	Heparin coupled to bovine serum albumin (heparin-BSA) was able to mediate binding between fibronectin and LTBP1.
T8	1100-1284	Sentence	denotes	Treatment of primary osteoblast cultures with heparin or heparin-BSA but not with chondroitin sulfate impaired LTBP1 deposition onto fibronectin without inhibiting expression of LTBP1.
T9	1285-1443	Sentence	denotes	Inhibition of LTBP1 incorporation was accompanied by reduced incorporation of latent TGF-beta into the ECM, with increased amounts of soluble latent TGF-beta.
T10	1444-1598	Sentence	denotes	Inhibition of attachment of glycosaminoglycans to the core proteins of proteoglycans by beta-d-xylosides also reduced incorporation of LTBP1 into the ECM.
T11	1599-1801	Sentence	denotes	These studies suggest that heparan sulfate proteoglycans may play a critical role in regulating TGF-beta availability by controlling the deposition of LTBP1 into the ECM in association with fibronectin.

GlyCosmos6-Glycan-Motif-Structure

Id	Subject	Object	Predicate	Lexical cue
T1	790-797	https://glytoucan.org/Structures/Glycans/G00021MO	denotes	heparin
T2	790-797	https://glytoucan.org/Structures/Glycans/G54161DR	denotes	heparin
T3	987-994	https://glytoucan.org/Structures/Glycans/G00021MO	denotes	Heparin
T4	987-994	https://glytoucan.org/Structures/Glycans/G54161DR	denotes	Heparin
T5	1028-1035	https://glytoucan.org/Structures/Glycans/G00021MO	denotes	heparin
T6	1028-1035	https://glytoucan.org/Structures/Glycans/G54161DR	denotes	heparin
T7	1146-1153	https://glytoucan.org/Structures/Glycans/G00021MO	denotes	heparin
T8	1146-1153	https://glytoucan.org/Structures/Glycans/G54161DR	denotes	heparin
T9	1157-1164	https://glytoucan.org/Structures/Glycans/G00021MO	denotes	heparin
T10	1157-1164	https://glytoucan.org/Structures/Glycans/G54161DR	denotes	heparin
T11	1182-1193	https://glytoucan.org/Structures/Glycans/G43702JT	denotes	chondroitin

PubmedHPO

Id	Subject	Object	Predicate	Lexical cue
T1	490-501	HP_0011846	denotes	osteoblasts
T2	750-760	HP_0011846	denotes	osteoblast
T3	1121-1131	HP_0011846	denotes	osteoblast

Glycan-GlyCosmos

Id	Subject	Object	Predicate	Lexical cue	image
T1	1182-1193	Glycan	denotes	chondroitin	https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T6	19-34	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T2	549-564	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T4	1626-1641	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW

GlyCosmos-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	19-34	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T2	549-564	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T3	1182-1193	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	chondroitin	http://www.glycoepitope.jp/epitopes/EP0081
T4	1626-1641	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086

GlyCosmos15-NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1006-1012	OrganismTaxon	denotes	bovine	9913

GlyCosmos15-CL

Id	Subject	Object	Predicate	Lexical cue	cl_id
T1	490-501	Cell	denotes	osteoblasts	http://purl.obolibrary.org/obo/CL:0000062
T2	506-517	Cell	denotes	fibroblasts	http://purl.obolibrary.org/obo/CL:0000057
T3	750-760	Cell	denotes	osteoblast	http://purl.obolibrary.org/obo/CL:0000062
T4	1121-1131	Cell	denotes	osteoblast	http://purl.obolibrary.org/obo/CL:0000062

GlyCosmos15-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	238-258	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T2	260-263	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T3	339-342	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T4	483-486	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T5	490-501	Body_part	denotes	osteoblasts	http://purl.obolibrary.org/obo/CL_0000062
T6	506-517	Body_part	denotes	fibroblasts	http://purl.obolibrary.org/obo/CL_0000057
T7	750-760	Body_part	denotes	osteoblast	http://purl.obolibrary.org/obo/CL_0000062
T8	1121-1131	Body_part	denotes	osteoblast	http://purl.obolibrary.org/obo/CL_0000062
T9	1388-1391	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T10	1594-1597	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T11	1765-1768	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-169	Sentence	denotes	Potential role for heparan sulfate proteoglycans in regulation of transforming growth factor-beta (TGF-beta) by modulating assembly of latent TGF-beta-binding protein-1.
T2	170-373	Sentence	denotes	Latent transforming growth factor-beta-binding proteins (LTBPs) are extracellular matrix (ECM) glycoproteins that play a major role in storage of latent TGF-beta in the ECM and regulate its availability.
T3	374-518	Sentence	denotes	We have previously identified fibronectin as a key molecule for incorporation of LTBP1 and TGF-beta into the ECM of osteoblasts and fibroblasts.
T4	519-629	Sentence	denotes	Here we provide evidence that heparan sulfate proteoglycans may mediate binding between LTBP1 and fibronectin.
T5	630-868	Sentence	denotes	We have localized critical domains in the N terminus of LTBP1 that are required for co-localization with fibronectin in osteoblast cultures and have identified heparin binding sites in the N terminus of LTBP1 between residues 345 and 487.
T6	869-986	Sentence	denotes	Solid-phase binding assays suggest that LTBP1 does not bind directly to fibronectin but that the binding is indirect.
T7	987-1099	Sentence	denotes	Heparin coupled to bovine serum albumin (heparin-BSA) was able to mediate binding between fibronectin and LTBP1.
T8	1100-1284	Sentence	denotes	Treatment of primary osteoblast cultures with heparin or heparin-BSA but not with chondroitin sulfate impaired LTBP1 deposition onto fibronectin without inhibiting expression of LTBP1.
T9	1285-1443	Sentence	denotes	Inhibition of LTBP1 incorporation was accompanied by reduced incorporation of latent TGF-beta into the ECM, with increased amounts of soluble latent TGF-beta.
T10	1444-1598	Sentence	denotes	Inhibition of attachment of glycosaminoglycans to the core proteins of proteoglycans by beta-d-xylosides also reduced incorporation of LTBP1 into the ECM.
T11	1599-1801	Sentence	denotes	These studies suggest that heparan sulfate proteoglycans may play a critical role in regulating TGF-beta availability by controlling the deposition of LTBP1 into the ECM in association with fibronectin.

GlyCosmos15-Sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-169	Sentence	denotes	Potential role for heparan sulfate proteoglycans in regulation of transforming growth factor-beta (TGF-beta) by modulating assembly of latent TGF-beta-binding protein-1.
T2	170-373	Sentence	denotes	Latent transforming growth factor-beta-binding proteins (LTBPs) are extracellular matrix (ECM) glycoproteins that play a major role in storage of latent TGF-beta in the ECM and regulate its availability.
T3	374-518	Sentence	denotes	We have previously identified fibronectin as a key molecule for incorporation of LTBP1 and TGF-beta into the ECM of osteoblasts and fibroblasts.
T4	519-629	Sentence	denotes	Here we provide evidence that heparan sulfate proteoglycans may mediate binding between LTBP1 and fibronectin.
T5	630-868	Sentence	denotes	We have localized critical domains in the N terminus of LTBP1 that are required for co-localization with fibronectin in osteoblast cultures and have identified heparin binding sites in the N terminus of LTBP1 between residues 345 and 487.
T6	869-986	Sentence	denotes	Solid-phase binding assays suggest that LTBP1 does not bind directly to fibronectin but that the binding is indirect.
T7	987-1099	Sentence	denotes	Heparin coupled to bovine serum albumin (heparin-BSA) was able to mediate binding between fibronectin and LTBP1.
T8	1100-1284	Sentence	denotes	Treatment of primary osteoblast cultures with heparin or heparin-BSA but not with chondroitin sulfate impaired LTBP1 deposition onto fibronectin without inhibiting expression of LTBP1.
T9	1285-1443	Sentence	denotes	Inhibition of LTBP1 incorporation was accompanied by reduced incorporation of latent TGF-beta into the ECM, with increased amounts of soluble latent TGF-beta.
T10	1444-1598	Sentence	denotes	Inhibition of attachment of glycosaminoglycans to the core proteins of proteoglycans by beta-d-xylosides also reduced incorporation of LTBP1 into the ECM.
T11	1599-1801	Sentence	denotes	These studies suggest that heparan sulfate proteoglycans may play a critical role in regulating TGF-beta availability by controlling the deposition of LTBP1 into the ECM in association with fibronectin.

GlyCosmos15-Glycan

Id	Subject	Object	Predicate	Lexical cue	image
T1	1182-1193	Glycan	denotes	chondroitin	https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T6	19-34	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T2	549-564	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T4	1626-1641	Glycan	denotes	heparan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW

GlyCosmos15-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	19-34	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T2	549-564	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086
T3	1182-1193	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	chondroitin	http://www.glycoepitope.jp/epitopes/EP0081
T4	1626-1641	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	heparan sulfate	http://www.glycoepitope.jp/epitopes/EP0086

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1006-1012	OrganismTaxon	denotes	bovine	9913

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	238-258	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T2	260-263	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T3	339-342	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T4	483-486	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T5	490-501	Body_part	denotes	osteoblasts	http://purl.obolibrary.org/obo/CL_0000062
T6	506-517	Body_part	denotes	fibroblasts	http://purl.obolibrary.org/obo/CL_0000057
T7	750-760	Body_part	denotes	osteoblast	http://purl.obolibrary.org/obo/CL_0000062
T8	1121-1131	Body_part	denotes	osteoblast	http://purl.obolibrary.org/obo/CL_0000062
T9	1388-1391	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T10	1594-1597	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012
T11	1765-1768	Body_part	denotes	ECM	http://purl.obolibrary.org/obo/GO_0031012

CL-cell

Id	Subject	Object	Predicate	Lexical cue	cl_id
T1	490-501	Cell	denotes	osteoblasts	http://purl.obolibrary.org/obo/CL:0000062
T2	506-517	Cell	denotes	fibroblasts	http://purl.obolibrary.org/obo/CL:0000057
T3	750-760	Cell	denotes	osteoblast	http://purl.obolibrary.org/obo/CL:0000062
T4	1121-1131	Cell	denotes	osteoblast	http://purl.obolibrary.org/obo/CL:0000062