PubMed:17574969
Annnotations
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 19-24 | gene:672 | denotes | BRCA1 |
| T1 | 56-95 | disease:C0346154 | denotes | malignant phyllodes tumor of the breast |
| T2 | 149-154 | gene:672 | denotes | BRCA1 |
| T3 | 106-123 | disease:C0678222 | denotes | breast carcinomas |
| T4 | 239-244 | gene:672 | denotes | BRCA1 |
| T5 | 256-266 | disease:C0007097 | denotes | carcinomas |
| T6 | 239-244 | gene:672 | denotes | BRCA1 |
| T7 | 390-410 | disease:C0206693 | denotes | medullary carcinomas |
| T8 | 239-244 | gene:672 | denotes | BRCA1 |
| T9 | 306-323 | disease:C1176475 | denotes | ductal carcinomas |
| T10 | 521-526 | gene:672 | denotes | BRCA1 |
| T11 | 574-613 | disease:C0346154 | denotes | malignant phyllodes tumor of the breast |
| T12 | 1109-1114 | gene:672 | denotes | BRCA1 |
| T13 | 1059-1074 | disease:C0010701 | denotes | phyllodes tumor |
| R1 | T0 | T1 | associated_with | BRCA1,malignant phyllodes tumor of the breast |
| R2 | T2 | T3 | associated_with | BRCA1,breast carcinomas |
| R3 | T4 | T5 | associated_with | BRCA1,carcinomas |
| R4 | T6 | T7 | associated_with | BRCA1,medullary carcinomas |
| R5 | T8 | T9 | associated_with | BRCA1,ductal carcinomas |
| R6 | T10 | T11 | associated_with | BRCA1,malignant phyllodes tumor of the breast |
| R7 | T12 | T13 | associated_with | BRCA1,phyllodes tumor |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 106-123 | HP_0003002 | denotes | breast carcinomas |
| T2 | 594-599 | HP_0002664 | denotes | tumor |
| T3 | 594-613 | HP_0003002 | denotes | tumor of the breast |
| T4 | 594-613 | HP_0100013 | denotes | tumor of the breast |
| T5 | 724-749 | HP_0003002 | denotes | Breast and Ovarian Cancer |
| T6 | 724-749 | HP_0100013 | denotes | Breast and Ovarian Cancer |
| T7 | 735-749 | HP_0100615 | denotes | Ovarian Cancer |
| T8 | 743-749 | HP_0002664 | denotes | Cancer |
| T9 | 917-922 | HP_0002664 | denotes | tumor |
| T10 | 1069-1074 | HP_0002664 | denotes | tumor |
| T1 | 106-123 | HP_0003002 | denotes | breast carcinomas |
| T2 | 594-599 | HP_0002664 | denotes | tumor |
| T3 | 594-613 | HP_0003002 | denotes | tumor of the breast |
| T4 | 594-613 | HP_0100013 | denotes | tumor of the breast |
| T5 | 724-749 | HP_0003002 | denotes | Breast and Ovarian Cancer |
| T6 | 724-749 | HP_0100013 | denotes | Breast and Ovarian Cancer |
| T7 | 735-749 | HP_0100615 | denotes | Ovarian Cancer |
| T8 | 743-749 | HP_0002664 | denotes | Cancer |
| T9 | 917-922 | HP_0002664 | denotes | tumor |
| T10 | 1069-1074 | HP_0002664 | denotes | tumor |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 17574969-1#52#57#gene672 | 149-154 | gene672 | denotes | BRCA1 |
| 17574969-1#9#26#diseaseC0678222 | 106-123 | diseaseC0678222 | denotes | breast carcinomas |
| 52#57#gene6729#26#diseaseC0678222 | 17574969-1#52#57#gene672 | 17574969-1#9#26#diseaseC0678222 | associated_with | BRCA1,breast carcinomas |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 106-123 | HP:0003002 | denotes | breast carcinomas |
| AB2 | 256-266 | HP:0030731 | denotes | carcinomas |
| AB3 | 313-323 | HP:0030731 | denotes | carcinomas |
| AB4 | 400-410 | HP:0030731 | denotes | carcinomas |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 89-95 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T2 | 106-112 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T3 | 607-613 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T4 | 724-730 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | Breast |
| PD-UBERON-AE-B_T5 | 346-366 | http://purl.obolibrary.org/obo/UBERON_0034768 | denotes | morphologic features |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE_T1 | 89-95 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE_T2 | 106-112 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE_T3 | 607-613 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE_T4 | 724-730 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | Breast |
| PD-UBERON-AE_T5 | 346-366 | http://purl.obolibrary.org/obo/UBERON_0034768 | denotes | morphologic features |
PubCasesORDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 97-123 | ORDO:227535 | denotes | Familial breast carcinomas |
| TI1 | 66-81 | ORDO:180261 | denotes | phyllodes tumor |
| AB2 | 584-599 | ORDO:180261 | denotes | phyllodes tumor |
| AB3 | 907-922 | ORDO:180261 | denotes | phyllodes tumor |
| AB4 | 1059-1074 | ORDO:180261 | denotes | phyllodes tumor |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-96 | Sentence | denotes | Association of the BRCA1 missense variant R1699W with a malignant phyllodes tumor of the breast. |
| TextSentencer_T2 | 97-238 | Sentence | denotes | Familial breast carcinomas that are attributable to BRCA1 or BRCA2 mutations have characteristic morphologic and immunhistochemical features. |
| TextSentencer_T3 | 239-472 | Sentence | denotes | BRCA1-associated carcinomas are poorly differentiated infiltrating ductal carcinomas frequently exhibiting morphologic features of typical or atypical medullary carcinomas such as prominent lymphocytic infiltrate and pushing margins. |
| TextSentencer_T4 | 473-614 | Sentence | denotes | We report on a patient carrying the deleterious BRCA1 germline mutation R1699W, who presented with a malignant phyllodes tumor of the breast. |
| TextSentencer_T5 | 615-811 | Sentence | denotes | The re-investigation of archival material by a reference pathologist of the German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC) revealed BRCA-associated pronounced pushing margins. |
| TextSentencer_T6 | 812-1003 | Sentence | denotes | In a total of 618 unrelated index patients who are registered in the GCHBOC database, no other phyllodes tumor has been described, while 10 carriers of the R1699W mutant have been identified. |
| TextSentencer_T7 | 1004-1185 | Sentence | denotes | We conclude that the histopathologic appearance of the phyllodes tumor indicates an association with the BRCA1 mutation R1699W although it is a rare event in BRCA-positive families. |
| T1 | 0-96 | Sentence | denotes | Association of the BRCA1 missense variant R1699W with a malignant phyllodes tumor of the breast. |
| T2 | 97-238 | Sentence | denotes | Familial breast carcinomas that are attributable to BRCA1 or BRCA2 mutations have characteristic morphologic and immunhistochemical features. |
| T3 | 239-472 | Sentence | denotes | BRCA1-associated carcinomas are poorly differentiated infiltrating ductal carcinomas frequently exhibiting morphologic features of typical or atypical medullary carcinomas such as prominent lymphocytic infiltrate and pushing margins. |
| T4 | 473-614 | Sentence | denotes | We report on a patient carrying the deleterious BRCA1 germline mutation R1699W, who presented with a malignant phyllodes tumor of the breast. |
| T5 | 615-811 | Sentence | denotes | The re-investigation of archival material by a reference pathologist of the German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC) revealed BRCA-associated pronounced pushing margins. |
| T6 | 812-1003 | Sentence | denotes | In a total of 618 unrelated index patients who are registered in the GCHBOC database, no other phyllodes tumor has been described, while 10 carriers of the R1699W mutant have been identified. |
| T7 | 1004-1185 | Sentence | denotes | We conclude that the histopathologic appearance of the phyllodes tumor indicates an association with the BRCA1 mutation R1699W although it is a rare event in BRCA-positive families. |