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PubMed:17194457 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
3808 31-58 ChemicalEntity denotes anabolic androgenic steroid MESH:D045165
3809 76-80 OrganismTaxon denotes rats NCBITaxon:10116
3810 90-99 ChemicalEntity denotes serotonin MESH:D012701
3811 173-200 ChemicalEntity denotes anabolic androgenic steroid MESH:D045165
3812 202-205 ChemicalEntity denotes AAS MESH:D045165
3813 226-235 ChemicalEntity denotes serotonin MESH:D012701
3814 237-256 ChemicalEntity denotes 5-hydroxytryptamine MESH:D012701
3815 258-262 ChemicalEntity denotes 5-HT MESH:D012701
3816 303-307 OrganismTaxon denotes rats NCBITaxon:10116
3817 309-318 ChemicalEntity denotes Serotonin MESH:D012701
3818 367-390 ChemicalEntity denotes parachlorophenylalanine MESH:D010134
3819 392-396 ChemicalEntity denotes PCPA MESH:D010134
3820 479-483 ChemicalEntity denotes PCPA MESH:D010134
3821 492-496 OrganismTaxon denotes rats NCBITaxon:10116
3822 525-529 OrganismTaxon denotes rats NCBITaxon:10116
3823 551-563 ChemicalEntity denotes testosterone MESH:D013739
3824 565-566 ChemicalEntity denotes T MESH:D013739
3825 632-644 DiseaseOrPhenotypicFeature denotes irritability MESH:D001523
3826 682-692 DiseaseOrPhenotypicFeature denotes aggression MESH:D001523
3827 718-728 DiseaseOrPhenotypicFeature denotes aggression MESH:D001523
3828 827-831 ChemicalEntity denotes 5-HT MESH:D012701
3829 852-878 ChemicalEntity denotes 5-hydroxyindoleacetic acid MESH:D006897
3830 880-886 ChemicalEntity denotes 5-HIAA MESH:D006897
3831 917-921 ChemicalEntity denotes PCPA MESH:D010134
3832 963-967 ChemicalEntity denotes 5-HT MESH:D012701
3833 972-978 ChemicalEntity denotes 5-HIAA MESH:D006897
3834 1018-1019 ChemicalEntity denotes T MESH:D013739
3835 1054-1058 ChemicalEntity denotes 5-HT MESH:D012701
3836 1063-1069 ChemicalEntity denotes 5-HIAA MESH:D006897
3837 1127-1131 ChemicalEntity denotes PCPA MESH:D010134
3838 1153-1157 ChemicalEntity denotes PCPA MESH:D010134
3839 1221-1233 DiseaseOrPhenotypicFeature denotes irritability MESH:D001523
3840 1295-1305 DiseaseOrPhenotypicFeature denotes aggression MESH:D001523
3841 1307-1308 ChemicalEntity denotes T MESH:D013739
3842 1344-1356 DiseaseOrPhenotypicFeature denotes irritability MESH:D001523
3843 1414-1424 DiseaseOrPhenotypicFeature denotes aggression MESH:D001523
3844 1464-1465 ChemicalEntity denotes T MESH:D013739
3845 1466-1470 ChemicalEntity denotes PCPA MESH:D010134
3846 1679-1682 ChemicalEntity denotes AAS MESH:D045165
3847 1706-1710 ChemicalEntity denotes 5-HT MESH:D012701
3848 1746-1765 DiseaseOrPhenotypicFeature denotes aggressive behavior MESH:D001523

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-100 Sentence denotes Behavioral effects of pubertal anabolic androgenic steroid exposure in male rats with low serotonin.
T2 101-308 Sentence denotes The goal of this study was to assess the interactive effects of chronic anabolic androgenic steroid (AAS) exposure and brain serotonin (5-hydroxytryptamine, 5-HT) depletion on behavior of pubertal male rats.
T3 309-451 Sentence denotes Serotonin was depleted beginning on postnatal day 26 with parachlorophenylalanine (PCPA 100 mg/kg, every other day); controls received saline.
T4 452-590 Sentence denotes At puberty (P40), half the PCPA-treated rats and half the saline-treated rats began treatment with testosterone (T, 5 mg/kg, 5 days/week).
T5 591-693 Sentence denotes Behavioral measures included locomotion, irritability, copulation, partner preference, and aggression.
T6 694-810 Sentence denotes Animals were tested for aggression in their home cage, both with and without physical provocation (mild tail pinch).
T7 811-916 Sentence denotes Brain levels of 5-HT and its metabolite, 5-hydroxyindoleacetic acid (5-HIAA), were determined using HPLC.
T8 917-1009 Sentence denotes PCPA significantly and substantially depleted 5-HT and 5-HIAA in all brain regions examined.
T9 1010-1132 Sentence denotes Chronic T treatment significantly decreased 5-HT and 5-HIAA in certain brain areas, but to a much lesser extent than PCPA.
T10 1133-1306 Sentence denotes Chronic exposure to PCPA alone significantly decreased locomotor activity and increased irritability but had no effect on sexual behavior, partner preference, or aggression.
T11 1307-1425 Sentence denotes T alone had no effect on locomotion, irritability, or sexual behavior but increased partner preference and aggression.
T12 1426-1622 Sentence denotes The most striking effect of combining T+PCPA was a significant increase in attack frequency as well as a significant decrease in the latency to attack, particularly following physical provocation.
T13 1623-1766 Sentence denotes Based on these data, it can be speculated that pubertal AAS users with low central 5-HT may be especially prone to exhibit aggressive behavior.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 76-80 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114
T4 303-307 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114
T7 492-496 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114
T10 525-529 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Behavioral
T2 71-75 GeneOrGeneProduct denotes male
T3 220-225 GeneOrGeneProduct denotes brain
T4 258-262 GeneOrGeneProduct denotes 5-HT
T5 264-273 GeneOrGeneProduct denotes depletion
T6 277-285 GeneOrGeneProduct denotes behavior
T7 298-302 GeneOrGeneProduct denotes male
T8 323-331 GeneOrGeneProduct denotes depleted
T9 332-344 GeneOrGeneProduct denotes beginning on
T10 392-396 GeneOrGeneProduct denotes PCPA
T11 401-403 GeneOrGeneProduct denotes mg
T12 414-419 GeneOrGeneProduct denotes other
T13 479-483 GeneOrGeneProduct denotes PCPA
T14 570-572 GeneOrGeneProduct denotes mg
T15 591-601 GeneOrGeneProduct denotes Behavioral
T16 620-630 GeneOrGeneProduct denotes locomotion
T17 707-713 GeneOrGeneProduct denotes tested
T18 743-747 GeneOrGeneProduct denotes cage
T19 798-802 GeneOrGeneProduct denotes tail
T20 803-808 GeneOrGeneProduct denotes pinch
T21 811-816 GeneOrGeneProduct denotes Brain
T22 827-831 GeneOrGeneProduct denotes 5-HT
T23 874-878 GeneOrGeneProduct denotes acid
T24 894-904 GeneOrGeneProduct denotes determined
T25 917-921 GeneOrGeneProduct denotes PCPA
T26 954-962 GeneOrGeneProduct denotes depleted
T27 963-967 GeneOrGeneProduct denotes 5-HT
T28 982-985 GeneOrGeneProduct denotes all
T29 986-991 GeneOrGeneProduct denotes brain
T30 1054-1058 GeneOrGeneProduct denotes 5-HT
T31 1081-1086 GeneOrGeneProduct denotes brain
T32 1087-1092 GeneOrGeneProduct denotes areas
T33 1127-1131 GeneOrGeneProduct denotes PCPA
T34 1153-1157 GeneOrGeneProduct denotes PCPA
T35 1198-1206 GeneOrGeneProduct denotes activity
T36 1262-1270 GeneOrGeneProduct denotes behavior
T37 1332-1342 GeneOrGeneProduct denotes locomotion
T38 1368-1376 GeneOrGeneProduct denotes behavior
T39 1466-1470 GeneOrGeneProduct denotes PCPA
T40 1508-1517 GeneOrGeneProduct denotes frequency
T41 1623-1628 GeneOrGeneProduct denotes Based
T42 1706-1710 GeneOrGeneProduct denotes 5-HT
T43 1757-1765 GeneOrGeneProduct denotes behavior

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 220-225 GeneOrGeneProduct denotes brain
T2 258-262 GeneOrGeneProduct denotes 5-HT
T3 277-285 GeneOrGeneProduct denotes behavior
T4 323-331 GeneOrGeneProduct denotes depleted
T5 414-419 GeneOrGeneProduct denotes other
T6 620-630 GeneOrGeneProduct denotes locomotion
T7 798-802 GeneOrGeneProduct denotes tail
T8 803-808 GeneOrGeneProduct denotes pinch
T9 811-816 GeneOrGeneProduct denotes Brain
T10 827-831 GeneOrGeneProduct denotes 5-HT
T11 874-878 GeneOrGeneProduct denotes acid
T12 954-962 GeneOrGeneProduct denotes depleted
T13 963-967 GeneOrGeneProduct denotes 5-HT
T14 986-991 GeneOrGeneProduct denotes brain
T15 1054-1058 GeneOrGeneProduct denotes 5-HT
T16 1081-1086 GeneOrGeneProduct denotes brain
T17 1262-1270 GeneOrGeneProduct denotes behavior
T18 1332-1342 GeneOrGeneProduct denotes locomotion
T19 1368-1376 GeneOrGeneProduct denotes behavior
T20 1508-1517 GeneOrGeneProduct denotes frequency
T21 1706-1710 GeneOrGeneProduct denotes 5-HT
T22 1757-1765 GeneOrGeneProduct denotes behavior

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 803-808 GeneOrGeneProduct denotes pinch

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 202-205 DiseaseOrPhenotypicFeature denotes AAS 0010589
T2 260-262 DiseaseOrPhenotypicFeature denotes HT 0007699
T3 829-831 DiseaseOrPhenotypicFeature denotes HT 0007699
T4 965-967 DiseaseOrPhenotypicFeature denotes HT 0007699
T5 1056-1058 DiseaseOrPhenotypicFeature denotes HT 0007699
T6 1647-1650 DiseaseOrPhenotypicFeature denotes can 0012833
T7 1679-1682 DiseaseOrPhenotypicFeature denotes AAS 0010589
T8 1708-1710 DiseaseOrPhenotypicFeature denotes HT 0007699

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 632-644 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T2 682-692 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T3 718-728 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T4 1221-1233 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T5 1295-1305 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T6 1344-1356 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T7 1414-1424 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T8 1746-1765 DiseaseOrPhenotypicFeature denotes aggressive behavior DISEASE

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 76-80 OrganismTaxon denotes rats
T2 303-307 OrganismTaxon denotes rats
T3 492-496 OrganismTaxon denotes rats
T4 525-529 OrganismTaxon denotes rats

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 632-644 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T2 682-692 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T3 718-728 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T4 1221-1233 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T5 1295-1305 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T6 1344-1356 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T7 1414-1424 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T8 1746-1765 DiseaseOrPhenotypicFeature denotes aggressive behavior DISEASE

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 31-58 ChemicalEntity denotes anabolic androgenic steroid http://purl.obolibrary.org/obo/CHEBI_50786
T2 90-99 ChemicalEntity denotes serotonin D012701|http://purl.obolibrary.org/obo/CHEBI_350546|http://purl.obolibrary.org/obo/CHEBI_28790
T5 173-200 ChemicalEntity denotes anabolic androgenic steroid http://purl.obolibrary.org/obo/CHEBI_50786
T6 202-205 ChemicalEntity denotes AAS http://purl.obolibrary.org/obo/CHEBI_73321|http://purl.obolibrary.org/obo/CHEBI_50786
T8 226-235 ChemicalEntity denotes serotonin D012701|http://purl.obolibrary.org/obo/CHEBI_350546|http://purl.obolibrary.org/obo/CHEBI_28790
T11 237-256 ChemicalEntity denotes 5-hydroxytryptamine D012701
T12 258-262 ChemicalEntity denotes 5-HT D012701|http://purl.obolibrary.org/obo/CHEBI_28790
T14 309-318 ChemicalEntity denotes Serotonin http://purl.obolibrary.org/obo/CHEBI_28790
T15 367-390 ChemicalEntity denotes parachlorophenylalanine ChemicalEntity
T16 392-396 ChemicalEntity denotes PCPA ChemicalEntity
T17 479-483 ChemicalEntity denotes PCPA ChemicalEntity
T18 551-563 ChemicalEntity denotes testosterone D013739|http://purl.obolibrary.org/obo/CHEBI_17347
T20 827-831 ChemicalEntity denotes 5-HT D012701|http://purl.obolibrary.org/obo/CHEBI_28790
T22 852-878 ChemicalEntity denotes 5-hydroxyindoleacetic acid http://purl.obolibrary.org/obo/CHEBI_27823
T23 880-886 ChemicalEntity denotes 5-HIAA D006897|http://purl.obolibrary.org/obo/CHEBI_27823
T25 917-921 ChemicalEntity denotes PCPA ChemicalEntity
T26 963-967 ChemicalEntity denotes 5-HT D012701|http://purl.obolibrary.org/obo/CHEBI_28790
T28 972-978 ChemicalEntity denotes 5-HIAA D006897|http://purl.obolibrary.org/obo/CHEBI_27823
T30 1054-1058 ChemicalEntity denotes 5-HT D012701|http://purl.obolibrary.org/obo/CHEBI_28790
T32 1063-1069 ChemicalEntity denotes 5-HIAA D006897|http://purl.obolibrary.org/obo/CHEBI_27823
T34 1127-1131 ChemicalEntity denotes PCPA ChemicalEntity
T35 1153-1157 ChemicalEntity denotes PCPA ChemicalEntity
T36 1466-1470 ChemicalEntity denotes PCPA ChemicalEntity
T37 1679-1682 ChemicalEntity denotes AAS http://purl.obolibrary.org/obo/CHEBI_73321|http://purl.obolibrary.org/obo/CHEBI_50786
T39 1706-1710 ChemicalEntity denotes 5-HT D012701|http://purl.obolibrary.org/obo/CHEBI_28790

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T39 1706-1710 ChemicalEntity denotes 5-HT http://purl.obolibrary.org/obo/CHEBI_28790|D012701
T37 1679-1682 ChemicalEntity denotes AAS http://purl.obolibrary.org/obo/CHEBI_50786|http://purl.obolibrary.org/obo/CHEBI_73321
T36 1466-1470 ChemicalEntity denotes PCPA ChemicalEntity
T35 1153-1157 ChemicalEntity denotes PCPA ChemicalEntity
T34 1127-1131 ChemicalEntity denotes PCPA ChemicalEntity
T32 1063-1069 ChemicalEntity denotes 5-HIAA http://purl.obolibrary.org/obo/CHEBI_27823|D006897
T30 1054-1058 ChemicalEntity denotes 5-HT http://purl.obolibrary.org/obo/CHEBI_28790|D012701
T28 972-978 ChemicalEntity denotes 5-HIAA http://purl.obolibrary.org/obo/CHEBI_27823|D006897
T26 963-967 ChemicalEntity denotes 5-HT http://purl.obolibrary.org/obo/CHEBI_28790|D012701
T25 917-921 ChemicalEntity denotes PCPA ChemicalEntity
T23 880-886 ChemicalEntity denotes 5-HIAA http://purl.obolibrary.org/obo/CHEBI_27823|D006897
T22 852-878 ChemicalEntity denotes 5-hydroxyindoleacetic acid http://purl.obolibrary.org/obo/CHEBI_27823
T20 827-831 ChemicalEntity denotes 5-HT http://purl.obolibrary.org/obo/CHEBI_28790|D012701
T18 551-563 ChemicalEntity denotes testosterone http://purl.obolibrary.org/obo/CHEBI_17347|D013739
T17 479-483 ChemicalEntity denotes PCPA ChemicalEntity
T16 392-396 ChemicalEntity denotes PCPA ChemicalEntity
T15 367-390 ChemicalEntity denotes parachlorophenylalanine ChemicalEntity
T14 309-318 ChemicalEntity denotes Serotonin http://purl.obolibrary.org/obo/CHEBI_28790
T12 258-262 ChemicalEntity denotes 5-HT http://purl.obolibrary.org/obo/CHEBI_28790|D012701
T11 237-256 ChemicalEntity denotes 5-hydroxytryptamine D012701
T8 226-235 ChemicalEntity denotes serotonin http://purl.obolibrary.org/obo/CHEBI_28790|http://purl.obolibrary.org/obo/CHEBI_350546|D012701
T6 202-205 ChemicalEntity denotes AAS http://purl.obolibrary.org/obo/CHEBI_50786|http://purl.obolibrary.org/obo/CHEBI_73321
T5 173-200 ChemicalEntity denotes anabolic androgenic steroid http://purl.obolibrary.org/obo/CHEBI_50786
T2 90-99 ChemicalEntity denotes serotonin http://purl.obolibrary.org/obo/CHEBI_28790|http://purl.obolibrary.org/obo/CHEBI_350546|D012701
T1 31-58 ChemicalEntity denotes anabolic androgenic steroid http://purl.obolibrary.org/obo/CHEBI_50786
T51804 803-808 GeneOrGeneProduct denotes pinch
T60418 1746-1765 DiseaseOrPhenotypicFeature denotes aggressive behavior DISEASE
T7 1414-1424 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T87572 1344-1356 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T4353 1295-1305 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T4 1221-1233 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T3 718-728 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T90695 682-692 DiseaseOrPhenotypicFeature denotes aggression DISEASE
T15703 632-644 DiseaseOrPhenotypicFeature denotes irritability DISEASE
T48129 525-529 OrganismTaxon denotes rats
T19909 492-496 OrganismTaxon denotes rats
T499 303-307 OrganismTaxon denotes rats
T46096 76-80 OrganismTaxon denotes rats

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 632-644 HP_0000737 denotes irritability
T2 682-692 HP_0000718 denotes aggression
T3 718-728 HP_0000718 denotes aggression
T4 1221-1233 HP_0000737 denotes irritability
T5 1295-1305 HP_0000718 denotes aggression
T6 1344-1356 HP_0000737 denotes irritability
T7 1414-1424 HP_0000718 denotes aggression
T8 1746-1756 HP_0000718 denotes aggressive
T9 1746-1765 HP_0000718 denotes aggressive behavior