PubMed:17166870
Annnotations
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-113 | Sentence | denotes | Association between an endoglin gene polymorphism and systemic sclerosis-related pulmonary arterial hypertension. |
T2 | 114-125 | Sentence | denotes | UNLABELLED: |
T3 | 126-262 | Sentence | denotes | Systemic sclerosis (SSc) is a connective tissue disorder characterized by early generalized microangiopathy with disturbed angiogenesis. |
T4 | 263-470 | Sentence | denotes | Endoglin gene (ENG) encodes a transmembrane glycoprotein which acts as an accessory receptor for the transforming growth factor-beta (TGF-beta) superfamily, and is crucial for maintaining vascular integrity. |
T5 | 471-583 | Sentence | denotes | A 6-base insertion in intron 7 (6bINS) of ENG has been reported to be associated with microvascular disturbance. |
T6 | 584-595 | Sentence | denotes | OBJECTIVES: |
T7 | 596-768 | Sentence | denotes | Our objective was to investigate the relationship between 6bINS and the vascular complication pulmonary arterial hypertension (PAH) in SSc in a French Caucasian population. |
T8 | 769-777 | Sentence | denotes | METHODS: |
T9 | 778-913 | Sentence | denotes | Two hundred eighty SSc cases containing 29/280 having PAH diagnosed by catheterism were compared with 140 patients with osteoarthritis. |
T10 | 914-1024 | Sentence | denotes | Genotyping was performed by polymerase-chain-reaction-based fluorescence and direct sequencing of genomic DNA. |
T11 | 1025-1033 | Sentence | denotes | RESULTS: |
T12 | 1034-1085 | Sentence | denotes | The polymorphism was in Hardy-Weinberg equilibrium. |
T13 | 1086-1377 | Sentence | denotes | We observed a significant lower frequency of 6bINS allele in SSc patients with associated PAH compared with controls [10.3 vs 23.9%, P = 0.01; odds ratio (OR) 0.37, 95% confidence interval (CI) 0.15-0.89], and a trend in comparison with SSc patients without PAH (10.3 vs 20.3%, P = 0.05; OR: |
T14 | 1378-1391 | Sentence | denotes | 0.45, 95% CI: |
T15 | 1392-1403 | Sentence | denotes | 0.19-1.08). |
T16 | 1404-1528 | Sentence | denotes | Genotypes carrying allele 6bINS were also less frequent in SSc patients with PAH than in controls (20.7 vs 42.9%, P = 0.02). |
T17 | 1529-1541 | Sentence | denotes | CONCLUSIONS: |
T18 | 1542-1703 | Sentence | denotes | Thus the frequency of 6bINS differs between SSc patients with or without PAH, suggesting the implication of ENG in this devastating vascular complication of SSc. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
3693 | 23-31 | GeneOrGeneProduct | denotes | endoglin | NCBIGene:2022 |
3694 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | MESH:D012595 |
3695 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | MESH:D000081029 |
3696 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | MESH:D012595 |
3697 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3698 | 218-233 | DiseaseOrPhenotypicFeature | denotes | microangiopathy | MESH:D057049 |
3699 | 263-271 | GeneOrGeneProduct | denotes | Endoglin | NCBIGene:2022 |
3700 | 278-281 | GeneOrGeneProduct | denotes | ENG | NCBIGene:2022 |
3701 | 307-319 | GeneOrGeneProduct | denotes | glycoprotein | NCBIGene:351 |
3702 | 364-395 | GeneOrGeneProduct | denotes | transforming growth factor-beta | NCBIGene:7040 |
3703 | 397-405 | GeneOrGeneProduct | denotes | TGF-beta | NCBIGene:7040 |
3704 | 473-489 | SequenceVariant | denotes | 6-base insertion | c|INS||6 |
3705 | 503-508 | SequenceVariant | denotes | 6bINS | c|INS||6 |
3706 | 513-516 | GeneOrGeneProduct | denotes | ENG | NCBIGene:2022 |
3707 | 654-659 | SequenceVariant | denotes | 6bINS | c|INS||6 |
3708 | 668-689 | DiseaseOrPhenotypicFeature | denotes | vascular complication | MESH:D014652 |
3709 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | MESH:D000081029 |
3710 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3711 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3712 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3713 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3714 | 884-892 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
3715 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | MESH:D010003 |
3716 | 1131-1136 | SequenceVariant | denotes | 6bINS | c|INS||6 |
3717 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3718 | 1151-1159 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
3719 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3720 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3721 | 1327-1335 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
3722 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3723 | 1430-1435 | SequenceVariant | denotes | 6bINS | c|INS||6 |
3724 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3725 | 1467-1475 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
3726 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3727 | 1564-1569 | SequenceVariant | denotes | 6bINS | c|INS||6 |
3728 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
3729 | 1590-1598 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
3730 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | MESH:D000081029 |
3731 | 1650-1653 | GeneOrGeneProduct | denotes | ENG | NCBIGene:2022 |
3732 | 1674-1695 | DiseaseOrPhenotypicFeature | denotes | vascular complication | MESH:D014652 |
3733 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | MESH:D012595 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | 0005100 |
T2 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | 0015924 |
T3 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | 0005100 |
T4 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | 0015924 |
T5 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | 0005178 |
LitCoin-SeqVar
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 503-508 | SequenceVariant | denotes | 6bINS |
T2 | 654-659 | SequenceVariant | denotes | 6bINS |
T3 | 1131-1136 | SequenceVariant | denotes | 6bINS |
T4 | 1430-1435 | SequenceVariant | denotes | 6bINS |
T5 | 1564-1569 | SequenceVariant | denotes | 6bINS |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 23-31 | GeneOrGeneProduct | denotes | endoglin |
T2 | 100-112 | GeneOrGeneProduct | denotes | hypertension |
T3 | 200-205 | GeneOrGeneProduct | denotes | early |
T4 | 263-271 | GeneOrGeneProduct | denotes | Endoglin |
T5 | 293-319 | GeneOrGeneProduct | denotes | transmembrane glycoprotein |
T6 | 347-355 | GeneOrGeneProduct | denotes | receptor |
T7 | 364-395 | GeneOrGeneProduct | denotes | transforming growth factor-beta |
T8 | 397-405 | GeneOrGeneProduct | denotes | TGF-beta |
T9 | 709-721 | GeneOrGeneProduct | denotes | hypertension |
T10 | 942-952 | GeneOrGeneProduct | denotes | polymerase |
T11 | 953-958 | GeneOrGeneProduct | denotes | chain |
T12 | 1118-1127 | GeneOrGeneProduct | denotes | frequency |
T13 | 1551-1560 | GeneOrGeneProduct | denotes | frequency |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 23-31 | GeneOrGeneProduct | denotes | endoglin |
T2 | 100-112 | GeneOrGeneProduct | denotes | hypertension |
T3 | 145-155 | GeneOrGeneProduct | denotes | (SSc) is a |
T4 | 200-205 | GeneOrGeneProduct | denotes | early |
T5 | 263-271 | GeneOrGeneProduct | denotes | Endoglin |
T6 | 293-319 | GeneOrGeneProduct | denotes | transmembrane glycoprotein |
T7 | 326-330 | GeneOrGeneProduct | denotes | acts |
T8 | 347-355 | GeneOrGeneProduct | denotes | receptor |
T9 | 364-395 | GeneOrGeneProduct | denotes | transforming growth factor-beta |
T10 | 397-405 | GeneOrGeneProduct | denotes | TGF-beta |
T11 | 475-479 | GeneOrGeneProduct | denotes | base |
T12 | 709-721 | GeneOrGeneProduct | denotes | hypertension |
T13 | 735-739 | GeneOrGeneProduct | denotes | in a |
T14 | 769-776 | GeneOrGeneProduct | denotes | METHODS |
T15 | 801-806 | GeneOrGeneProduct | denotes | cases |
T16 | 942-952 | GeneOrGeneProduct | denotes | polymerase |
T17 | 953-958 | GeneOrGeneProduct | denotes | chain |
T18 | 968-973 | GeneOrGeneProduct | denotes | based |
T19 | 1058-1063 | GeneOrGeneProduct | denotes | Hardy |
T20 | 1118-1127 | GeneOrGeneProduct | denotes | frequency |
T21 | 1551-1560 | GeneOrGeneProduct | denotes | frequency |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | D012595 |
T2 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T3 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | D012595 |
T4 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T5 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T6 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T7 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T8 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T9 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T10 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | D010003 |
T11 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T12 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T13 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T14 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T15 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T16 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T17 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T18 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T19 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 23-31 | GeneOrGeneProduct | denotes | endoglin |
T2 | 263-271 | GeneOrGeneProduct | denotes | Endoglin |
T3 | 293-319 | GeneOrGeneProduct | denotes | transmembrane glycoprotein |
T4 | 364-395 | GeneOrGeneProduct | denotes | transforming growth factor-beta |
T5 | 397-405 | GeneOrGeneProduct | denotes | TGF-beta |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | 0005100 |
T2 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | 0024533|0015924 |
T4 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | 0005100 |
T5 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T6 | 156-182 | DiseaseOrPhenotypicFeature | denotes | connective tissue disorder | 0003900 |
T7 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | 0024533|0015924 |
T9 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T11 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T12 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T13 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T15 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | 0005178 |
T16 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T17 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T19 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T20 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T22 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T23 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T25 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
T26 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | 0015924|0024533 |
T28 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | 0005100 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | D012595 |
T2 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T3 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | D012595 |
T4 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T5 | 218-233 | DiseaseOrPhenotypicFeature | denotes | microangiopathy | DISEASE |
T6 | 668-689 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE |
T7 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T8 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T9 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T10 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T11 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T12 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | D010003 |
T13 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T14 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T15 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T16 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T17 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T18 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T19 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T20 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T21 | 1674-1695 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE |
T22 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | D012595 |
T2 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T3 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | D012595 |
T4 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T5 | 218-233 | DiseaseOrPhenotypicFeature | denotes | microangiopathy | DISEASE |
T6 | 668-689 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE |
T7 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 |
T8 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T9 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T10 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T11 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T12 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | D010003 |
T13 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T14 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T15 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T16 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T17 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T18 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T19 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
T20 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 |
T21 | 1674-1695 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE |
T22 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 723-726 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
T5 | 832-835 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
T9 | 1176-1179 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
T13 | 1344-1347 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
T17 | 1481-1484 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
T21 | 1615-1618 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_53305|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_104011 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 884-892 | OrganismTaxon | denotes | patients |
T2 | 1151-1159 | OrganismTaxon | denotes | patients |
T3 | 1327-1335 | OrganismTaxon | denotes | patients |
T4 | 1467-1475 | OrganismTaxon | denotes | patients |
T5 | 1590-1598 | OrganismTaxon | denotes | patients |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T21 | 1615-1618 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T17 | 1481-1484 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T13 | 1344-1347 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T9 | 1176-1179 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T5 | 832-835 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T1 | 723-726 | ChemicalEntity | denotes | PAH | http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305 | |
T90565 | 397-405 | GeneOrGeneProduct | denotes | TGF-beta | ||
T4 | 364-395 | GeneOrGeneProduct | denotes | transforming growth factor-beta | ||
T3 | 293-319 | GeneOrGeneProduct | denotes | transmembrane glycoprotein | ||
T2 | 263-271 | GeneOrGeneProduct | denotes | Endoglin | ||
T3851 | 23-31 | GeneOrGeneProduct | denotes | endoglin | ||
T22 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T92818 | 1674-1695 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE | |
T20 | 1615-1618 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T19 | 1586-1589 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T18 | 1481-1484 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T68731 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T16 | 1344-1347 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T15 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T14 | 1176-1179 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T33282 | 1147-1150 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T12 | 898-912 | DiseaseOrPhenotypicFeature | denotes | osteoarthritis | D010003 | |
T11 | 832-835 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T10 | 797-800 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T86237 | 731-734 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T8 | 723-726 | DiseaseOrPhenotypicFeature | denotes | PAH | D000081029 | |
T7 | 690-721 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 | |
T6 | 668-689 | DiseaseOrPhenotypicFeature | denotes | vascular complication | DISEASE | |
T14156 | 218-233 | DiseaseOrPhenotypicFeature | denotes | microangiopathy | DISEASE | |
T65914 | 146-149 | DiseaseOrPhenotypicFeature | denotes | SSc | D012595 | |
T88367 | 126-144 | DiseaseOrPhenotypicFeature | denotes | Systemic sclerosis | D012595 | |
T96334 | 81-112 | DiseaseOrPhenotypicFeature | denotes | pulmonary arterial hypertension | D000081029 | |
T94954 | 54-72 | DiseaseOrPhenotypicFeature | denotes | systemic sclerosis | D012595 | |
T18725 | 1590-1598 | OrganismTaxon | denotes | patients | ||
T61043 | 1467-1475 | OrganismTaxon | denotes | patients | ||
T93461 | 1327-1335 | OrganismTaxon | denotes | patients | ||
T57119 | 1151-1159 | OrganismTaxon | denotes | patients | ||
T44649 | 884-892 | OrganismTaxon | denotes | patients | ||
T97443 | 1564-1569 | SequenceVariant | denotes | 6bINS | ||
T10156 | 1430-1435 | SequenceVariant | denotes | 6bINS | ||
T37731 | 1131-1136 | SequenceVariant | denotes | 6bINS | ||
T75926 | 654-659 | SequenceVariant | denotes | 6bINS | ||
T78758 | 503-508 | SequenceVariant | denotes | 6bINS |
DisGeNET
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T0 | 23-31 | gene:2022 | denotes | endoglin |
T1 | 54-72 | disease:C0036421 | denotes | systemic sclerosis |
T2 | 23-31 | gene:2022 | denotes | endoglin |
T3 | 81-112 | disease:C0152171 | denotes | pulmonary arterial hypertension |
T4 | 23-31 | gene:2022 | denotes | endoglin |
T5 | 81-112 | disease:C2973725 | denotes | pulmonary arterial hypertension |
T6 | 23-31 | gene:2022 | denotes | endoglin |
T7 | 81-112 | disease:C3714844 | denotes | pulmonary arterial hypertension |
R1 | T0 | T1 | associated_with | endoglin,systemic sclerosis |
R2 | T2 | T3 | associated_with | endoglin,pulmonary arterial hypertension |
R3 | T4 | T5 | associated_with | endoglin,pulmonary arterial hypertension |
R4 | T6 | T7 | associated_with | endoglin,pulmonary arterial hypertension |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 156-182 | HP_0003549 | denotes | connective tissue disorder |
DisGeNET5_gene_disease
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
17166870-0#23#31#gene2022 | 23-31 | gene2022 | denotes | endoglin |
17166870-0#54#72#diseaseC0036421 | 54-72 | diseaseC0036421 | denotes | systemic sclerosis |
17166870-0#81#112#diseaseC3203102 | 81-112 | diseaseC3203102 | denotes | pulmonary arterial hypertension |
23#31#gene202254#72#diseaseC0036421 | 17166870-0#23#31#gene2022 | 17166870-0#54#72#diseaseC0036421 | associated_with | endoglin,systemic sclerosis |
23#31#gene202281#112#diseaseC3203102 | 17166870-0#23#31#gene2022 | 17166870-0#81#112#diseaseC3203102 | associated_with | endoglin,pulmonary arterial hypertension |
tmVarCorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 503-508 | DNAMutation:|INS||6 | denotes | 6bINS |
T2 | 654-659 | DNAMutation:|INS||6 | denotes | 6bINS |
T3 | 1131-1136 | DNAMutation:|INS||6 | denotes | 6bINS |
T4 | 1430-1435 | DNAMutation:|INS||6 | denotes | 6bINS |
T5 | 1564-1569 | DNAMutation:|INS||6 | denotes | 6bINS |