PubMed:1716630
Annnotations
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 87-94 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T2 | 87-94 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T3 | 87-94 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T4 | 87-94 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T5 | 87-94 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T6 | 87-94 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T7 | 698-705 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T8 | 698-705 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T9 | 698-705 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T10 | 698-705 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T11 | 698-705 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T12 | 698-705 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T13 | 947-954 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T14 | 947-954 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T15 | 947-954 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T16 | 947-954 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T17 | 947-954 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T18 | 947-954 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T19 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T20 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T21 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T22 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T23 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T24 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 87-94 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T2 | 87-94 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T3 | 87-94 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T4 | 87-94 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T5 | 87-94 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T6 | 87-94 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T7 | 698-705 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T8 | 698-705 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T9 | 698-705 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T10 | 698-705 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T11 | 698-705 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T12 | 698-705 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T13 | 947-954 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T14 | 947-954 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T15 | 947-954 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T16 | 947-954 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T17 | 947-954 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T18 | 947-954 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
| T19 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg003 | denotes | Lewis x |
| T20 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg004 | denotes | Lewis x |
| T21 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg005 | denotes | Lewis x |
| T22 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg006 | denotes | Lewis x |
| T23 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Lewis x |
| T24 | 1224-1231 | https://acgg.asia/db/ggdb/info/gg008 | denotes | Lewis x |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 87-94 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T3 | 99-104 | Glycan_Motif | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G22418PV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T5 | 666-685 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T6 | 698-705 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T8 | 940-954 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T9 | 947-954 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T11 | 1121-1126 | Glycan_Motif | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G22418PV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T13 | 1201-1206 | Glycan_Motif | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G22418PV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T15 | 1217-1231 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T16 | 1224-1231 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T18 | 1321-1326 | Glycan_Motif | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G22418PV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T20 | 1726-1731 | Glycan_Motif | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G22418PV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-153 | Sentence | denotes | Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. |
| T2 | 154-321 | Sentence | denotes | We have used the human Lewis blood group fucosyltransferase cDNA and cross-hybridization procedures to isolate a human gene that encodes a distinct fucosyltransferase. |
| T3 | 322-521 | Sentence | denotes | Its DNA sequence predicts a type II transmembrane protein whose sequence is identical to 133 of 231 amino acids at corresponding positions within the catalytic domain of the Lewis fucosyltransferase. |
| T4 | 522-760 | Sentence | denotes | When expressed by transfection in cultured cell lines, this gene determines expression of a fucosyltransferase capable of efficiently utilizing N-acetyllactosamine to form the Lewis x determinant (Gal beta 1----4[Fuc alpha 1----3]GlcNAc). |
| T5 | 761-967 | Sentence | denotes | By contrast, biochemical and flow cytometry analyses suggest that the enzyme cannot efficiently utilize the type II acceptor NeuNAc alpha 2----3Gal beta 1----4GlcNAc, to form the sialyl Lewis x determinant. |
| T6 | 968-1173 | Sentence | denotes | In Chinese hamster ovary cells, however, the enzyme can determine expression of the alpha 2----3-sialylated, alpha 1----3-fucosylated structure known as VIM-2, a putative oligosaccharide ligand for ELAM-1. |
| T7 | 1174-1419 | Sentence | denotes | Cell adhesion assays using VIM-2-positive, sialyl Lewis x-negative transfected Chinese hamster ovary cells indicate that surface expression of the VIM-2 determinant is not sufficient to confer ELAM-1-dependent adhesive properties upon the cells. |
| T8 | 1420-1661 | Sentence | denotes | These results demonstrate that substantial structural similarities can exist between mammalian glycosyltransferases with closely related enzymatic properties, thus facilitating isolation of their cognate genes by cross-hybridization methods. |
| T9 | 1662-1816 | Sentence | denotes | The results further suggest that cell surface expression of the VIM-2 determinant is not necessarily sufficient to mediate ELAM-1-dependent cell adhesion. |
| T1 | 0-153 | Sentence | denotes | Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. |
| T2 | 154-321 | Sentence | denotes | We have used the human Lewis blood group fucosyltransferase cDNA and cross-hybridization procedures to isolate a human gene that encodes a distinct fucosyltransferase. |
| T3 | 322-521 | Sentence | denotes | Its DNA sequence predicts a type II transmembrane protein whose sequence is identical to 133 of 231 amino acids at corresponding positions within the catalytic domain of the Lewis fucosyltransferase. |
| T4 | 522-760 | Sentence | denotes | When expressed by transfection in cultured cell lines, this gene determines expression of a fucosyltransferase capable of efficiently utilizing N-acetyllactosamine to form the Lewis x determinant (Gal beta 1----4[Fuc alpha 1----3]GlcNAc). |
| T5 | 761-967 | Sentence | denotes | By contrast, biochemical and flow cytometry analyses suggest that the enzyme cannot efficiently utilize the type II acceptor NeuNAc alpha 2----3Gal beta 1----4GlcNAc, to form the sialyl Lewis x determinant. |
| T6 | 968-1173 | Sentence | denotes | In Chinese hamster ovary cells, however, the enzyme can determine expression of the alpha 2----3-sialylated, alpha 1----3-fucosylated structure known as VIM-2, a putative oligosaccharide ligand for ELAM-1. |
| T7 | 1174-1419 | Sentence | denotes | Cell adhesion assays using VIM-2-positive, sialyl Lewis x-negative transfected Chinese hamster ovary cells indicate that surface expression of the VIM-2 determinant is not sufficient to confer ELAM-1-dependent adhesive properties upon the cells. |
| T8 | 1420-1661 | Sentence | denotes | These results demonstrate that substantial structural similarities can exist between mammalian glycosyltransferases with closely related enzymatic properties, thus facilitating isolation of their cognate genes by cross-hybridization methods. |
| T9 | 1662-1816 | Sentence | denotes | The results further suggest that cell surface expression of the VIM-2 determinant is not necessarily sufficient to mediate ELAM-1-dependent cell adhesion. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 183-188 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 183-188 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 87-94 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T2 | 87-94 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T3 | 99-104 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | VIM-2 |
| T4 | 99-104 | https://glytoucan.org/Structures/Glycans/G22418PV | denotes | VIM-2 |
| T5 | 666-685 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T6 | 698-705 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T7 | 698-705 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T8 | 940-954 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T9 | 947-954 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T10 | 947-954 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T11 | 1121-1126 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | VIM-2 |
| T12 | 1121-1126 | https://glytoucan.org/Structures/Glycans/G22418PV | denotes | VIM-2 |
| T13 | 1201-1206 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | VIM-2 |
| T14 | 1201-1206 | https://glytoucan.org/Structures/Glycans/G22418PV | denotes | VIM-2 |
| T15 | 1217-1231 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T16 | 1224-1231 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T17 | 1224-1231 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T18 | 1321-1326 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | VIM-2 |
| T19 | 1321-1326 | https://glytoucan.org/Structures/Glycans/G22418PV | denotes | VIM-2 |
| T20 | 1726-1731 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | VIM-2 |
| T21 | 1726-1731 | https://glytoucan.org/Structures/Glycans/G22418PV | denotes | VIM-2 |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 87-94 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T2 | 99-104 | http://www.glycoepitope.jp/epitopes/AN0111 | denotes | VIM-2 |
| T3 | 99-104 | http://www.glycoepitope.jp/epitopes/EP0019 | denotes | VIM-2 |
| T4 | 698-705 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T5 | 940-954 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T6 | 947-954 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T7 | 1121-1126 | http://www.glycoepitope.jp/epitopes/AN0111 | denotes | VIM-2 |
| T8 | 1121-1126 | http://www.glycoepitope.jp/epitopes/EP0019 | denotes | VIM-2 |
| T9 | 1201-1206 | http://www.glycoepitope.jp/epitopes/AN0111 | denotes | VIM-2 |
| T10 | 1201-1206 | http://www.glycoepitope.jp/epitopes/EP0019 | denotes | VIM-2 |
| T11 | 1217-1231 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T12 | 1224-1231 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T13 | 1321-1326 | http://www.glycoepitope.jp/epitopes/AN0111 | denotes | VIM-2 |
| T14 | 1321-1326 | http://www.glycoepitope.jp/epitopes/EP0019 | denotes | VIM-2 |
| T15 | 1726-1731 | http://www.glycoepitope.jp/epitopes/AN0111 | denotes | VIM-2 |
| T16 | 1726-1731 | http://www.glycoepitope.jp/epitopes/EP0019 | denotes | VIM-2 |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 355-357 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
| PD-GlycoGenes20190927-B_T2 | 874-876 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 752-758 | chem:24139 | denotes | GlcNAc |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 183-188 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 87-94 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 99-104 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T3 | 698-705 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T4 | 886-892 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T5 | 940-954 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T6 | 1121-1126 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T7 | 1201-1206 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T8 | 1217-1231 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T9 | 1321-1326 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T10 | 1726-1731 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 87-94 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 99-104 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T4 | 698-705 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T5 | 940-954 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T6 | 1121-1126 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T8 | 1201-1206 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T10 | 1217-1231 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T11 | 1321-1326 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T13 | 1726-1731 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 183-188 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 358-371 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T3 | 987-992 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T4 | 1269-1274 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 23-28 | OrganismTaxon | denotes | human | 9606 |
| T2 | 171-176 | OrganismTaxon | denotes | human | 9606 |
| T3 | 267-272 | OrganismTaxon | denotes | human | 9606 |
| T4 | 971-986 | OrganismTaxon | denotes | Chinese hamster | 10029 |
| T5 | 1253-1268 | OrganismTaxon | denotes | Chinese hamster | 10029 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 556-569 | Cell | denotes | cultured cell | http://purl.obolibrary.org/obo/CL:0000010 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 183-188 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-153 | Sentence | denotes | Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. |
| T2 | 154-321 | Sentence | denotes | We have used the human Lewis blood group fucosyltransferase cDNA and cross-hybridization procedures to isolate a human gene that encodes a distinct fucosyltransferase. |
| T3 | 322-521 | Sentence | denotes | Its DNA sequence predicts a type II transmembrane protein whose sequence is identical to 133 of 231 amino acids at corresponding positions within the catalytic domain of the Lewis fucosyltransferase. |
| T4 | 522-760 | Sentence | denotes | When expressed by transfection in cultured cell lines, this gene determines expression of a fucosyltransferase capable of efficiently utilizing N-acetyllactosamine to form the Lewis x determinant (Gal beta 1----4[Fuc alpha 1----3]GlcNAc). |
| T5 | 761-967 | Sentence | denotes | By contrast, biochemical and flow cytometry analyses suggest that the enzyme cannot efficiently utilize the type II acceptor NeuNAc alpha 2----3Gal beta 1----4GlcNAc, to form the sialyl Lewis x determinant. |
| T6 | 968-1173 | Sentence | denotes | In Chinese hamster ovary cells, however, the enzyme can determine expression of the alpha 2----3-sialylated, alpha 1----3-fucosylated structure known as VIM-2, a putative oligosaccharide ligand for ELAM-1. |
| T7 | 1174-1419 | Sentence | denotes | Cell adhesion assays using VIM-2-positive, sialyl Lewis x-negative transfected Chinese hamster ovary cells indicate that surface expression of the VIM-2 determinant is not sufficient to confer ELAM-1-dependent adhesive properties upon the cells. |
| T8 | 1420-1661 | Sentence | denotes | These results demonstrate that substantial structural similarities can exist between mammalian glycosyltransferases with closely related enzymatic properties, thus facilitating isolation of their cognate genes by cross-hybridization methods. |
| T9 | 1662-1816 | Sentence | denotes | The results further suggest that cell surface expression of the VIM-2 determinant is not necessarily sufficient to mediate ELAM-1-dependent cell adhesion. |
| T1 | 0-153 | Sentence | denotes | Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. |
| T2 | 154-321 | Sentence | denotes | We have used the human Lewis blood group fucosyltransferase cDNA and cross-hybridization procedures to isolate a human gene that encodes a distinct fucosyltransferase. |
| T3 | 322-521 | Sentence | denotes | Its DNA sequence predicts a type II transmembrane protein whose sequence is identical to 133 of 231 amino acids at corresponding positions within the catalytic domain of the Lewis fucosyltransferase. |
| T4 | 522-760 | Sentence | denotes | When expressed by transfection in cultured cell lines, this gene determines expression of a fucosyltransferase capable of efficiently utilizing N-acetyllactosamine to form the Lewis x determinant (Gal beta 1----4[Fuc alpha 1----3]GlcNAc). |
| T5 | 761-967 | Sentence | denotes | By contrast, biochemical and flow cytometry analyses suggest that the enzyme cannot efficiently utilize the type II acceptor NeuNAc alpha 2----3Gal beta 1----4GlcNAc, to form the sialyl Lewis x determinant. |
| T6 | 968-1173 | Sentence | denotes | In Chinese hamster ovary cells, however, the enzyme can determine expression of the alpha 2----3-sialylated, alpha 1----3-fucosylated structure known as VIM-2, a putative oligosaccharide ligand for ELAM-1. |
| T7 | 1174-1419 | Sentence | denotes | Cell adhesion assays using VIM-2-positive, sialyl Lewis x-negative transfected Chinese hamster ovary cells indicate that surface expression of the VIM-2 determinant is not sufficient to confer ELAM-1-dependent adhesive properties upon the cells. |
| T8 | 1420-1661 | Sentence | denotes | These results demonstrate that substantial structural similarities can exist between mammalian glycosyltransferases with closely related enzymatic properties, thus facilitating isolation of their cognate genes by cross-hybridization methods. |
| T9 | 1662-1816 | Sentence | denotes | The results further suggest that cell surface expression of the VIM-2 determinant is not necessarily sufficient to mediate ELAM-1-dependent cell adhesion. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-153 | Sentence | denotes | Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. |
| T2 | 154-321 | Sentence | denotes | We have used the human Lewis blood group fucosyltransferase cDNA and cross-hybridization procedures to isolate a human gene that encodes a distinct fucosyltransferase. |
| T3 | 322-521 | Sentence | denotes | Its DNA sequence predicts a type II transmembrane protein whose sequence is identical to 133 of 231 amino acids at corresponding positions within the catalytic domain of the Lewis fucosyltransferase. |
| T4 | 522-760 | Sentence | denotes | When expressed by transfection in cultured cell lines, this gene determines expression of a fucosyltransferase capable of efficiently utilizing N-acetyllactosamine to form the Lewis x determinant (Gal beta 1----4[Fuc alpha 1----3]GlcNAc). |
| T5 | 761-967 | Sentence | denotes | By contrast, biochemical and flow cytometry analyses suggest that the enzyme cannot efficiently utilize the type II acceptor NeuNAc alpha 2----3Gal beta 1----4GlcNAc, to form the sialyl Lewis x determinant. |
| T6 | 968-1173 | Sentence | denotes | In Chinese hamster ovary cells, however, the enzyme can determine expression of the alpha 2----3-sialylated, alpha 1----3-fucosylated structure known as VIM-2, a putative oligosaccharide ligand for ELAM-1. |
| T7 | 1174-1419 | Sentence | denotes | Cell adhesion assays using VIM-2-positive, sialyl Lewis x-negative transfected Chinese hamster ovary cells indicate that surface expression of the VIM-2 determinant is not sufficient to confer ELAM-1-dependent adhesive properties upon the cells. |
| T8 | 1420-1661 | Sentence | denotes | These results demonstrate that substantial structural similarities can exist between mammalian glycosyltransferases with closely related enzymatic properties, thus facilitating isolation of their cognate genes by cross-hybridization methods. |
| T9 | 1662-1816 | Sentence | denotes | The results further suggest that cell surface expression of the VIM-2 determinant is not necessarily sufficient to mediate ELAM-1-dependent cell adhesion. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 87-94 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 99-104 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T3 | 698-705 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T4 | 886-892 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T5 | 940-954 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T6 | 1121-1126 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T7 | 1201-1206 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T8 | 1217-1231 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T9 | 1321-1326 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
| T10 | 1726-1731 | Glycan | denotes | VIM-2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G22418PV |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 87-94 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 99-104 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T4 | 698-705 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T5 | 940-954 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T6 | 1121-1126 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T8 | 1201-1206 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T10 | 1217-1231 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T11 | 1321-1326 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
| T13 | 1726-1731 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | VIM-2 | http://www.glycoepitope.jp/epitopes/AN0111|http://www.glycoepitope.jp/epitopes/EP0019 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 23-28 | OrganismTaxon | denotes | human | 9606 |
| T2 | 171-176 | OrganismTaxon | denotes | human | 9606 |
| T3 | 267-272 | OrganismTaxon | denotes | human | 9606 |
| T4 | 971-986 | OrganismTaxon | denotes | Chinese hamster | 10029 |
| T5 | 1253-1268 | OrganismTaxon | denotes | Chinese hamster | 10029 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 183-188 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 358-371 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T3 | 987-992 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T4 | 1269-1274 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 556-569 | Cell | denotes | cultured cell | http://purl.obolibrary.org/obo/CL:0000010 |