PubMed:17165506 JSONTXT

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    {"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":270,"end":278},"obj":"HP_0000726"}],"text":"[Effects of ear point needle embedding therapy on memory disorder and expression of beta-amyloid protein in the rat of vascular dementia].\nOBJECTIVE: To study the mechanism of auricular acupuncture for improvement of learning and memory disorders in the rat of vascular dementia (VD).\nMETHODS: The vascular dementia rat model was made by 4-vessel occlusion method. Four groups, a sham operation group, a normal control group, a model group and an auricular acupuncture group were set up. After acupuncture was given at auricular points, Brain and Kidney. Immunohistochemical analysis, behavioural observation and computer image analysis were made.\nRESULTS: Auricular acupuncture could decrease significantly the beta-amyloid protein (A beta) immunoreactivive neurons and increase its average optical density in the parietal cortex of the VD rats (P \u003c 0.05).\nCONCLUSION: Auricular acupuncture can reduce or inhibit the over-production of Abeta in the brain, so as to improve the learning and memory capacity of the VD model rat."}