PubMed:1705836
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-37 | RNA | denotes | 1,25-Dihydroxyvitamin D3 receptor RNA |
| T2 | 53-72 | cell_type | denotes | hematopoietic cells |
| T3 | 167-189 | cell_type | denotes | myeloid leukemic cells |
| T4 | 271-291 | protein | denotes | 1,25(OH)2D3 receptor |
| T5 | 326-350 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T6 | 354-373 | cell_type | denotes | hematopoietic cells |
| T7 | 434-458 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T8 | 470-524 | cell_type | denotes | proliferating and nonproliferating hematopoietic cells |
| T9 | 553-577 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T10 | 611-630 | cell_type | denotes | hematopoietic cells |
| T11 | 668-681 | cell_type | denotes | T lymphocytes |
| T12 | 708-712 | cell_line | denotes | KG-1 |
| T13 | 714-725 | cell_line | denotes | myeloblasts |
| T14 | 728-733 | cell_line | denotes | HL-60 |
| T15 | 735-748 | cell_line | denotes | promyelocytes |
| T16 | 751-755 | cell_line | denotes | ML-3 |
| T17 | 757-772 | cell_line | denotes | myelomonoblasts |
| T18 | 775-779 | cell_line | denotes | U937 |
| T19 | 781-786 | cell_line | denotes | THP-1 |
| T20 | 788-798 | cell_line | denotes | monoblasts |
| T21 | 801-805 | cell_line | denotes | K562 |
| T22 | 807-820 | cell_line | denotes | erythroblasts |
| T23 | 827-832 | cell_line | denotes | S-LB1 |
| T24 | 834-866 | cell_line | denotes | HTLV-1-transfected T lymphocytes |
| T25 | 869-889 | RNA | denotes | Receptor transcripts |
| T26 | 1004-1025 | protein | denotes | 1,25(OH)2D3 receptors |
| T27 | 1032-1050 | cell_line | denotes | B lymphocyte lines |
| T28 | 1082-1106 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T29 | 1143-1174 | cell_line | denotes | lymphoid/myeloid somatic hybrid |
| T30 | 1219-1243 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T31 | 1247-1260 | cell_type | denotes | B lymphocytes |
| T32 | 1295-1306 | cell_line | denotes | HL-60 cells |
| T33 | 1399-1419 | protein | denotes | 1,25(OH)2D3 receptor |
| T34 | 1476-1484 | protein | denotes | receptor |
| T35 | 1561-1589 | protein | denotes | 1,25(OH)2D3 receptor protein |
| T36 | 1609-1620 | cell_line | denotes | HL-60 cells |
| T37 | 1646-1667 | protein | denotes | 1,25(OH)2D3 receptors |
| T38 | 1763-1787 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T39 | 1837-1842 | cell_line | denotes | HL-60 |
| T40 | 1857-1869 | cell_type | denotes | granulocytes |
| T41 | 1873-1884 | cell_type | denotes | macrophages |
| T42 | 1898-1909 | cell_type | denotes | macrophages |
| T43 | 1949-1973 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T44 | 1988-2028 | cell_type | denotes | nondividing peripheral blood lymphocytes |
| T45 | 2069-2093 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T46 | 2161-2185 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T47 | 2226-2250 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T48 | 2254-2267 | cell_type | denotes | T lymphocytes |
| T49 | 2417-2441 | RNA | denotes | 1,25(OH)2D3 receptor RNA |
| T50 | 2570-2591 | protein | denotes | 1,25(OH)2D3 receptors |
| T51 | 2595-2608 | cell_type | denotes | myeloid cells |
| T52 | 2613-2640 | cell_type | denotes | proliferating T lymphocytes |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-73 | Sentence | denotes | 1,25-Dihydroxyvitamin D3 receptor RNA: expression in hematopoietic cells. |
| S2 | 74-292 | Sentence | denotes | 1,25-Dihydroxyvitamin D3 [1,25(OH)2D3] induces differentiation and inhibits proliferation of myeloid leukemic cells from various lines and patients; these effects are probably mediated through the 1,25(OH)2D3 receptor. |
| S3 | 293-374 | Sentence | denotes | Little is known of expression of 1,25(OH)2D3 receptor RNA in hematopoietic cells. |
| S4 | 375-525 | Sentence | denotes | We examined the expression and modulation of expression of 1,25(OH)2D3 receptor RNA in various proliferating and nonproliferating hematopoietic cells. |
| S5 | 526-868 | Sentence | denotes | Constitutive expression of 1,25(OH)2D3 receptor RNA was detected in various kinds of hematopoietic cells, including macrophages and activated T lymphocytes, as well as in cell lines KG-1 (myeloblasts), HL-60 (promyelocytes), ML-3 (myelomonoblasts), U937, THP-1 (monoblasts), K562 (erythroblasts), and S-LB1 (HTLV-1-transfected T lymphocytes). |
| S6 | 869-950 | Sentence | denotes | Receptor transcripts were 4.6 kilobases (kb), and no variant sizes were observed. |
| S7 | 951-1026 | Sentence | denotes | All cell lines examined in this group also expressed 1,25(OH)2D3 receptors. |
| S8 | 1027-1294 | Sentence | denotes | Most B lymphocyte lines expressed negligible levels of 1,25(OH)2D3 receptor RNA and protein; however; analysis of a lymphoid/myeloid somatic hybrid suggested that suppression of expression of 1,25(OH)2D3 receptor RNA in B lymphocytes may be a dominant characteristic. |
| S9 | 1295-1446 | Sentence | denotes | HL-60 cells were cultured with 10(-7) mol/L 1,25(OH)2D3 for 24 to 72 hours, and levels of expression of 1,25(OH)2D3 receptor and its RNA were examined. |
| S10 | 1447-1541 | Sentence | denotes | Levels of RNA coding for the receptor were not modulated by exposure to high levels of ligand. |
| S11 | 1542-1739 | Sentence | denotes | Levels of occupied 1,25(OH)2D3 receptor protein increased in these HL-60 cells; but the total number of 1,25(OH)2D3 receptors decreased about 50% at 24 hours and returned toward normal at 72 hours. |
| S12 | 1740-1885 | Sentence | denotes | Steady-state levels of 1,25(OH)2D3 receptor RNA were not affected by terminal differentiation of HL-60 toward either granulocytes or macrophages. |
| S13 | 1886-1974 | Sentence | denotes | Nondividing macrophages from normal individuals also expressed 1,25(OH)2D3 receptor RNA. |
| S14 | 1975-2205 | Sentence | denotes | In contrast, nondividing peripheral blood lymphocytes from normal individuals did not express 1,25(OH)2D3 receptor RNA; with stimulation of proliferation of these cells, accumulation of 1,25(OH)2D3 receptor RNA increased markedly. |
| S15 | 2206-2367 | Sentence | denotes | Half-life (t1/2) of 1,25(OH)2D3 receptor RNA in T lymphocytes was short (1 hour) as determined by measuring decay of the message after addition of actinomycin D. |
| S16 | 2368-2502 | Sentence | denotes | Consistent with this short t1/2, accumulation of 1,25(OH)2D3 receptor RNA increased in cells as their protein synthesis was inhibited. |
| S17 | 2503-2641 | Sentence | denotes | Further studies are required to understand the physiologic role of 1,25(OH)2D3 receptors in myeloid cells and proliferating T lymphocytes. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C3 | 0-24 | NP | denotes | 1,25-Dihydroxyvitamin D3 |
| C2 | 0-33 | NP | denotes | 1,25-Dihydroxyvitamin D3 receptor |
| C1 | 0-37 | NP | denotes | 1,25-Dihydroxyvitamin D3 receptor RNA |
| C4 | 53-72 | NP | denotes | hematopoietic cells |
| C5 | 74-112 | NP | denotes | 1,25-Dihydroxyvitamin D3 [1,25(OH)2D3] |
| C6 | 167-189 | NP | denotes | myeloid leukemic cells |
| C7 | 267-291 | NP | denotes | the 1,25(OH)2D3 receptor |
| C9 | 326-350 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C8 | 312-350 | NP | denotes | expression of 1,25(OH)2D3 receptor RNA |
| C10 | 354-373 | NP | denotes | hematopoietic cells |
| C12 | 434-458 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C11 | 420-458 | NP | denotes | expression of 1,25(OH)2D3 receptor RNA |
| C14 | 553-577 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C13 | 526-577 | NP | denotes | Constitutive expression of 1,25(OH)2D3 receptor RNA |
| C16 | 611-630 | NP | denotes | hematopoietic cells |
| C17 | 642-653 | NP | denotes | macrophages |
| C18 | 728-749 | NP | denotes | HL-60 (promyelocytes) |
| C15 | 594-867 | NP | denotes | various kinds of hematopoietic cells, including macrophages and activated T lymphocytes, as well as in cell lines KG-1 (myeloblasts), HL-60 (promyelocytes), ML-3 (myelomonoblasts), U937, THP-1 (monoblasts), K562 (erythroblasts), and S-LB1 (HTLV-1-transfected T lymphocytes) |
| C19 | 978-988 | NP | denotes | this group |
| C20 | 1004-1025 | NP | denotes | 1,25(OH)2D3 receptors |
| C21 | 1082-1106 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C23 | 1219-1243 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C22 | 1205-1243 | NP | denotes | expression of 1,25(OH)2D3 receptor RNA |
| C24 | 1295-1306 | NP | denotes | HL-60 cells |
| C25 | 1399-1419 | NP | denotes | 1,25(OH)2D3 receptor |
| C27 | 1424-1427 | NP | denotes | its |
| C26 | 1424-1431 | NP | denotes | its RNA |
| C28 | 1472-1484 | NP | denotes | the receptor |
| C29 | 1603-1620 | NP | denotes | these HL-60 cells |
| C30 | 1646-1667 | NP | denotes | 1,25(OH)2D3 receptors |
| C31 | 1763-1787 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C32 | 1837-1842 | NP | denotes | HL-60 |
| C33 | 1873-1884 | NP | denotes | macrophages |
| C34 | 1949-1973 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C35 | 1988-2028 | NP | denotes | nondividing peripheral blood lymphocytes |
| C36 | 2069-2093 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C37 | 2132-2143 | NP | denotes | these cells |
| C38 | 2161-2185 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C40 | 2226-2250 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C39 | 2206-2267 | NP | denotes | Half-life (t1/2) of 1,25(OH)2D3 receptor RNA in T lymphocytes |
| C41 | 2384-2399 | NP | denotes | this short t1/2 |
| C42 | 2417-2441 | NP | denotes | 1,25(OH)2D3 receptor RNA |
| C43 | 2455-2460 | NP | denotes | cells |
| C44 | 2464-2469 | NP | denotes | their |
| C45 | 2570-2591 | NP | denotes | 1,25(OH)2D3 receptors |
| C46 | 2595-2608 | NP | denotes | myeloid cells |
| R1 | C5 | C3 | coref-ident | "1,25-Dihydroxyvitamin D3 [1,25(OH)2D3]","1,25-Dihydroxyvitamin D3" |
| R2 | C7 | C2 | coref-ident | "the 1,25(OH)2D3 receptor","1,25-Dihydroxyvitamin D3 receptor" |
| R3 | C9 | C1 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25-Dihydroxyvitamin D3 receptor RNA" |
| R4 | C10 | C4 | coref-ident | hematopoietic cells,hematopoietic cells |
| R5 | C12 | C9 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R6 | C11 | C8 | coref-other | "expression of 1,25(OH)2D3 receptor RNA","expression of 1,25(OH)2D3 receptor RNA" |
| R7 | C14 | C1 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25-Dihydroxyvitamin D3 receptor RNA" |
| R8 | C13 | C11 | coref-ident | "Constitutive expression of 1,25(OH)2D3 receptor RNA","expression of 1,25(OH)2D3 receptor RNA" |
| R9 | C16 | C4 | coref-ident | hematopoietic cells,hematopoietic cells |
| R10 | C19 | C15 | coref-ident | this group,"various kinds of hematopoietic cells, including macrophages and activated T lymphocytes, as well as in cell lines KG-1 (myeloblasts), HL-60 (promyelocytes), ML-3 (myelomonoblasts), U937, THP-1 (monoblasts), K562 (erythroblasts), and S-LB1 (HTLV-1-transfected T lymphocytes)" |
| R11 | C20 | C7 | coref-other | "1,25(OH)2D3 receptors","the 1,25(OH)2D3 receptor" |
| R12 | C21 | C12 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R13 | C23 | C21 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R14 | C22 | C13 | coref-other | "expression of 1,25(OH)2D3 receptor RNA","Constitutive expression of 1,25(OH)2D3 receptor RNA" |
| R15 | C25 | C20 | coref-ident | "1,25(OH)2D3 receptor","1,25(OH)2D3 receptors" |
| R16 | C27 | C25 | coref-pron | its,"1,25(OH)2D3 receptor" |
| R17 | C26 | C23 | coref-pron | its RNA,"1,25(OH)2D3 receptor RNA" |
| R18 | C28 | C25 | coref-ident | the receptor,"1,25(OH)2D3 receptor" |
| R19 | C29 | C24 | coref-ident | these HL-60 cells,HL-60 cells |
| R20 | C30 | C25 | coref-other | "1,25(OH)2D3 receptors","1,25(OH)2D3 receptor" |
| R21 | C31 | C26 | coref-ident | "1,25(OH)2D3 receptor RNA",its RNA |
| R22 | C32 | C18 | coref-ident | HL-60,HL-60 (promyelocytes) |
| R23 | C33 | C17 | coref-ident | macrophages,macrophages |
| R24 | C34 | C31 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R25 | C36 | C34 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R26 | C37 | C35 | coref-ident | these cells,nondividing peripheral blood lymphocytes |
| R27 | C38 | C36 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R28 | C40 | C38 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R29 | C41 | C39 | coref-ident | this short t1/2,"Half-life (t1/2) of 1,25(OH)2D3 receptor RNA in T lymphocytes" |
| R30 | C42 | C40 | coref-ident | "1,25(OH)2D3 receptor RNA","1,25(OH)2D3 receptor RNA" |
| R31 | C44 | C43 | coref-pron | their,cells |
| R32 | C45 | C30 | coref-ident | "1,25(OH)2D3 receptors","1,25(OH)2D3 receptors" |
| R33 | C46 | C6 | coref-ident | myeloid cells,myeloid leukemic cells |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-33 | protein_family_or_group | denotes | 1,25-Dihydroxyvitamin D3 receptor |
| T2 | 53-72 | cell_type | denotes | hematopoietic cells |
| T3 | 74-98 | lipid | denotes | 1,25-Dihydroxyvitamin D3 |
| T4 | 100-111 | lipid | denotes | 1,25(OH)2D3 |
| T5 | 167-189 | cell_type | denotes | myeloid leukemic cells |
| T6 | 213-221 | multi_cell | denotes | patients |
| T7 | 271-291 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T8 | 326-346 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T9 | 354-373 | cell_type | denotes | hematopoietic cells |
| T10 | 434-454 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T11 | 553-573 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T12 | 611-630 | cell_type | denotes | hematopoietic cells |
| T13 | 668-681 | cell_type | denotes | T lymphocytes |
| T14 | 708-712 | cell_line | denotes | KG-1 |
| T15 | 714-725 | cell_line | denotes | myeloblasts |
| T16 | 728-733 | cell_line | denotes | HL-60 |
| T17 | 735-748 | cell_line | denotes | promyelocytes |
| T18 | 751-755 | cell_line | denotes | ML-3 |
| T19 | 757-772 | cell_line | denotes | myelomonoblasts |
| T20 | 775-779 | cell_line | denotes | U937 |
| T21 | 781-786 | cell_line | denotes | THP-1 |
| T22 | 788-798 | cell_line | denotes | monoblasts |
| T23 | 801-805 | cell_line | denotes | K562 |
| T24 | 807-820 | cell_line | denotes | erythroblasts |
| T25 | 827-832 | cell_line | denotes | S-LB1 |
| T26 | 834-852 | cell_line | denotes | HTLV-1-transfected |
| T27 | 853-866 | cell_type | denotes | T lymphocytes |
| T28 | 869-889 | RNA_family_or_group | denotes | Receptor transcripts |
| T29 | 1004-1025 | protein_family_or_group | denotes | 1,25(OH)2D3 receptors |
| T30 | 1032-1050 | cell_line | denotes | B lymphocyte lines |
| T31 | 1082-1102 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T32 | 1143-1174 | cell_line | denotes | lymphoid/myeloid somatic hybrid |
| T33 | 1219-1239 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T34 | 1247-1260 | cell_type | denotes | B lymphocytes |
| T35 | 1295-1306 | cell_line | denotes | HL-60 cells |
| T36 | 1339-1350 | lipid | denotes | 1,25(OH)2D3 |
| T37 | 1399-1419 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T38 | 1476-1484 | protein_family_or_group | denotes | receptor |
| T39 | 1534-1540 | other_name | denotes | ligand |
| T40 | 1561-1581 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T41 | 1609-1620 | cell_line | denotes | HL-60 cells |
| T42 | 1646-1667 | protein_family_or_group | denotes | 1,25(OH)2D3 receptors |
| T43 | 1763-1783 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T44 | 1837-1842 | cell_line | denotes | HL-60 |
| T45 | 1857-1869 | cell_type | denotes | granulocytes |
| T46 | 1873-1884 | cell_type | denotes | macrophages |
| T47 | 1898-1909 | cell_type | denotes | macrophages |
| T48 | 1915-1933 | multi_cell | denotes | normal individuals |
| T49 | 1949-1969 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T50 | 1988-2028 | cell_type | denotes | nondividing peripheral blood lymphocytes |
| T51 | 2034-2052 | multi_cell | denotes | normal individuals |
| T52 | 2069-2089 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T53 | 2161-2181 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T54 | 2226-2246 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T55 | 2254-2267 | cell_type | denotes | T lymphocytes |
| T56 | 2353-2366 | other_organic_compound | denotes | actinomycin D |
| T57 | 2417-2437 | protein_family_or_group | denotes | 1,25(OH)2D3 receptor |
| T58 | 2570-2591 | protein_family_or_group | denotes | 1,25(OH)2D3 receptors |
| T59 | 2595-2608 | cell_type | denotes | myeloid cells |
| T60 | 2613-2626 | cell_type | denotes | proliferating |
| T61 | 2627-2640 | cell_type | denotes | T lymphocytes |