PubMed:16990813
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 875-878 | Disease | denotes | ESC | http://purl.obolibrary.org/obo/MONDO_0007579 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 71-80 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T2 | 110-119 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 650-656 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T2 | 663-669 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T3 | 711-717 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T4 | 723-729 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 650-656 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T2 | 663-669 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T3 | 711-717 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T4 | 723-729 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 94-99 | OrganismTaxon | denotes | Human | 9606 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 59-80 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T2 | 71-80 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T3 | 100-119 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T4 | 110-119 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 59-80 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T2 | 110-119 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T3 | 814-824 | Body_part | denotes | cell-cycle | http://purl.obolibrary.org/obo/UBERON_2000098 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 71-80 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T2 | 110-119 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-93 | Sentence | denotes | Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. |
| T2 | 94-198 | Sentence | denotes | Human embryonic stem cell (hESC) lines are known to be morphologically and phenotypically heterogeneous. |
| T3 | 199-383 | Sentence | denotes | The functional nature and relationship of cells residing within hESC cultures, however, has not been evaluated because isolation of single hESCs is limited to drug or manual selection. |
| T4 | 384-567 | Sentence | denotes | Here we provide a quantitative method using flow cytometry to isolate and clonally expand hESCs based on undifferentiated markers, alone or in combination with a fluorescent reporter. |
| T5 | 568-696 | Sentence | denotes | This method allowed for isolation of stage-specific embryonic antigen-3-positive (SSEA-3+) and SSEA-3- cells from hESC cultures. |
| T6 | 697-901 | Sentence | denotes | Although both SSEA-3+ and SSEA-3- cells could initiate pluripotent hESC cultures, we show that they possess distinct cell-cycle properties, clonogenic capacity and expression of ESC transcription factors. |
| T7 | 902-1106 | Sentence | denotes | Our study provides formal evidence for heterogeneity among self-renewing pluripotent hESCs, illustrating that this isolation technique will be instrumental in further dissecting the biology of hESC lines. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 650-656 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T2 | 663-669 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T3 | 711-717 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T4 | 723-729 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 650-656 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T2 | 663-669 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T3 | 711-717 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T4 | 723-729 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 94-99 | OrganismTaxon | denotes | Human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 59-80 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T2 | 110-119 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T3 | 814-824 | Body_part | denotes | cell-cycle | http://purl.obolibrary.org/obo/UBERON_2000098 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 59-80 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T2 | 71-80 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T3 | 100-119 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T4 | 110-119 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |