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DisGeNET

Id Subject Object Predicate Lexical cue
T0 1650-1654 gene:3438 denotes IFNA
T1 1554-1569 disease:C0011649 denotes mature teratoma
T2 1650-1654 gene:3438 denotes IFNA
T3 1554-1569 disease:C1368910 denotes mature teratoma
T4 1650-1654 gene:3439 denotes IFNA
T5 1554-1569 disease:C0011649 denotes mature teratoma
T6 1650-1654 gene:3439 denotes IFNA
T7 1554-1569 disease:C1368910 denotes mature teratoma
T8 1650-1654 gene:3447 denotes IFNA
T9 1554-1569 disease:C0011649 denotes mature teratoma
T10 1650-1654 gene:3447 denotes IFNA
T11 1554-1569 disease:C1368910 denotes mature teratoma
T12 1650-1654 gene:3451 denotes IFNA
T13 1554-1569 disease:C0011649 denotes mature teratoma
T14 1650-1654 gene:3451 denotes IFNA
T15 1554-1569 disease:C1368910 denotes mature teratoma
T16 1650-1654 gene:3440 denotes IFNA
T17 1554-1569 disease:C0011649 denotes mature teratoma
T18 1650-1654 gene:3440 denotes IFNA
T19 1554-1569 disease:C1368910 denotes mature teratoma
R1 T0 T1 associated_with IFNA,mature teratoma
R2 T2 T3 associated_with IFNA,mature teratoma
R3 T4 T5 associated_with IFNA,mature teratoma
R4 T6 T7 associated_with IFNA,mature teratoma
R5 T8 T9 associated_with IFNA,mature teratoma
R6 T10 T11 associated_with IFNA,mature teratoma
R7 T12 T13 associated_with IFNA,mature teratoma
R8 T14 T15 associated_with IFNA,mature teratoma
R9 T16 T17 associated_with IFNA,mature teratoma
R10 T18 T19 associated_with IFNA,mature teratoma

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 59-79 HP_0100616 denotes Testicular teratomas
T2 70-79 HP_0009792 denotes teratomas
T3 125-131 HP_0002664 denotes tumors
T4 177-182 HP_0002664 denotes tumor

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
16982812-11#161#165#gene3438 1650-1654 gene3438 denotes IFNA
16982812-11#161#165#gene3440 1650-1654 gene3440 denotes IFNA
16982812-11#161#165#gene3439 1650-1654 gene3439 denotes IFNA
16982812-11#161#165#gene3447 1650-1654 gene3447 denotes IFNA
16982812-11#161#165#gene3451 1650-1654 gene3451 denotes IFNA
16982812-11#65#80#diseaseC0011649 1554-1569 diseaseC0011649 denotes mature teratoma
16982812-11#65#80#diseaseC1368910 1554-1569 diseaseC1368910 denotes mature teratoma
16982812-11#65#80#diseaseC0011649 1554-1569 diseaseC0011649 denotes mature teratoma
16982812-11#65#80#diseaseC1368910 1554-1569 diseaseC1368910 denotes mature teratoma
16982812-11#65#80#diseaseC0011649 1554-1569 diseaseC0011649 denotes mature teratoma
16982812-11#65#80#diseaseC1368910 1554-1569 diseaseC1368910 denotes mature teratoma
16982812-11#65#80#diseaseC0011649 1554-1569 diseaseC0011649 denotes mature teratoma
16982812-11#65#80#diseaseC1368910 1554-1569 diseaseC1368910 denotes mature teratoma
16982812-11#65#80#diseaseC0011649 1554-1569 diseaseC0011649 denotes mature teratoma
16982812-11#65#80#diseaseC1368910 1554-1569 diseaseC1368910 denotes mature teratoma
161#165#gene343865#80#diseaseC0011649 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC1368910 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC0011649 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC1368910 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC0011649 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC1368910 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC0011649 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC1368910 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC0011649 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343865#80#diseaseC1368910 16982812-11#161#165#gene3438 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC0011649 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC1368910 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC0011649 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC1368910 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC0011649 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC1368910 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC0011649 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC1368910 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC0011649 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344065#80#diseaseC1368910 16982812-11#161#165#gene3440 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC0011649 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC1368910 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC0011649 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC1368910 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC0011649 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC1368910 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC0011649 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC1368910 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC0011649 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene343965#80#diseaseC1368910 16982812-11#161#165#gene3439 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC0011649 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC1368910 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC0011649 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC1368910 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC0011649 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC1368910 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC0011649 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC1368910 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC0011649 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene344765#80#diseaseC1368910 16982812-11#161#165#gene3447 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC0011649 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC1368910 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC0011649 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC1368910 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC0011649 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC1368910 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC0011649 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC1368910 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC0011649 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC0011649 associated_with IFNA,mature teratoma
161#165#gene345165#80#diseaseC1368910 16982812-11#161#165#gene3451 16982812-11#65#80#diseaseC1368910 associated_with IFNA,mature teratoma

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T1187 1650-1654 gene:3438 denotes IFNA
T1188 1554-1569 disease:C0011649 denotes mature teratoma
R1 T1187 T1188 associated_with IFNA,mature teratoma
R2 T1187 T1188 associated_with IFNA,mature teratoma
R3 T1187 T1188 associated_with IFNA,mature teratoma
R4 T1187 T1188 associated_with IFNA,mature teratoma
R5 T1187 T1188 associated_with IFNA,mature teratoma
R6 T1187 T1188 associated_with IFNA,mature teratoma
R7 T1187 T1188 associated_with IFNA,mature teratoma
R8 T1187 T1188 associated_with IFNA,mature teratoma
R9 T1187 T1188 associated_with IFNA,mature teratoma
R10 T1187 T1188 associated_with IFNA,mature teratoma

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-49 Sentence denotes Clonal origin of metastatic testicular teratomas.
TextSentencer_T2 50-58 Sentence denotes PURPOSE:
TextSentencer_T3 59-200 Sentence denotes Testicular teratomas in adult patients are histologically diverse tumors that frequently coexist with other germ cell tumor (GCT) components.
TextSentencer_T4 201-348 Sentence denotes These mixed GCTs often metastasize to retroperitoneal lymph nodes where multiple GCT elements are frequently present in the same metastatic lesion.
TextSentencer_T5 349-525 Sentence denotes Neither the genetic relationships among the different components in metastatic lesions nor the relationships between primary and metastatic GCT components have been elucidated.
TextSentencer_T6 526-546 Sentence denotes EXPERIMENTAL DESIGN:
TextSentencer_T7 547-677 Sentence denotes We examined metastases from 31 patients who underwent primary retroperitoneal lymph node dissection for metastatic testicular GCT.
TextSentencer_T8 678-760 Sentence denotes All patients had metastatic mature teratoma with one or more other GCT components.
TextSentencer_T9 761-868 Sentence denotes This study included a total of 72 metastatic GCT components and 16 primary GCT components from 31 patients.
TextSentencer_T10 869-1015 Sentence denotes Genomic DNA samples from each component were prepared from formalin-fixed, paraffin-embedded tissue sections using laser-assisted microdissection.
TextSentencer_T11 1016-1254 Sentence denotes Loss of heterozygosity (LOH) assays for seven microsatellite polymorphic markers on chromosomes 1p36 (D1S1646), 9p21 (D9S171 and IFNA), 9q21 (D9S303), 13q22-q31 (D13S317), 18q22 (D18S543), and 18q21 (D18S60) were done to assess clonality.
TextSentencer_T12 1255-1263 Sentence denotes RESULTS:
TextSentencer_T13 1264-1363 Sentence denotes Twenty-nine of 31 (94%) cases showed allelic loss in one or more components of the metastatic GCTs.
TextSentencer_T14 1364-1488 Sentence denotes Twenty-nine of 31 mature teratomas showed allelic loss in at least one of seven microsatellite polymorphic markers analyzed.
TextSentencer_T15 1489-1771 Sentence denotes The frequency of allelic loss in informative cases of metastatic mature teratoma was 27% (8 of 30) with D1S1646, 34% (10 of 29) with D9S171, 37% (10 of 27) with IFNA, 27% (8 of 30) with D9S303, 46% (13 of 28) with D13S317, 26% (7 of 27) with D18S543, and 36% (10 of 28) with D18S60.
TextSentencer_T16 1772-1969 Sentence denotes Completely concordant allelic loss patterns between the mature teratoma and all of the other metastatic GCT components were seen in 26 of 29 cases in which the mature teratoma component showed LOH.
TextSentencer_T17 1970-2048 Sentence denotes Nearly identical allelic loss patterns were seen in the three remaining cases.
TextSentencer_T18 2049-2184 Sentence denotes In six cases analyzed, LOH patterns of each metastatic component were compared with each GCT component of the primary testicular tumor.
TextSentencer_T19 2185-2285 Sentence denotes In all six cases, each primary and metastatic component showed an identical pattern of allelic loss.
TextSentencer_T20 2286-2297 Sentence denotes CONCLUSION:
TextSentencer_T21 2298-2468 Sentence denotes Our data support the common clonal origin of metastatic mature teratomas with other components of metastatic testicular GCTs and with each component of the primary tumor.
T1 0-49 Sentence denotes Clonal origin of metastatic testicular teratomas.
T2 50-58 Sentence denotes PURPOSE:
T3 59-200 Sentence denotes Testicular teratomas in adult patients are histologically diverse tumors that frequently coexist with other germ cell tumor (GCT) components.
T4 201-348 Sentence denotes These mixed GCTs often metastasize to retroperitoneal lymph nodes where multiple GCT elements are frequently present in the same metastatic lesion.
T5 349-525 Sentence denotes Neither the genetic relationships among the different components in metastatic lesions nor the relationships between primary and metastatic GCT components have been elucidated.
T6 526-546 Sentence denotes EXPERIMENTAL DESIGN:
T7 547-677 Sentence denotes We examined metastases from 31 patients who underwent primary retroperitoneal lymph node dissection for metastatic testicular GCT.
T8 678-760 Sentence denotes All patients had metastatic mature teratoma with one or more other GCT components.
T9 761-868 Sentence denotes This study included a total of 72 metastatic GCT components and 16 primary GCT components from 31 patients.
T10 869-1015 Sentence denotes Genomic DNA samples from each component were prepared from formalin-fixed, paraffin-embedded tissue sections using laser-assisted microdissection.
T11 1016-1254 Sentence denotes Loss of heterozygosity (LOH) assays for seven microsatellite polymorphic markers on chromosomes 1p36 (D1S1646), 9p21 (D9S171 and IFNA), 9q21 (D9S303), 13q22-q31 (D13S317), 18q22 (D18S543), and 18q21 (D18S60) were done to assess clonality.
T12 1255-1263 Sentence denotes RESULTS:
T13 1264-1363 Sentence denotes Twenty-nine of 31 (94%) cases showed allelic loss in one or more components of the metastatic GCTs.
T14 1364-1488 Sentence denotes Twenty-nine of 31 mature teratomas showed allelic loss in at least one of seven microsatellite polymorphic markers analyzed.
T15 1489-1771 Sentence denotes The frequency of allelic loss in informative cases of metastatic mature teratoma was 27% (8 of 30) with D1S1646, 34% (10 of 29) with D9S171, 37% (10 of 27) with IFNA, 27% (8 of 30) with D9S303, 46% (13 of 28) with D13S317, 26% (7 of 27) with D18S543, and 36% (10 of 28) with D18S60.
T16 1772-1969 Sentence denotes Completely concordant allelic loss patterns between the mature teratoma and all of the other metastatic GCT components were seen in 26 of 29 cases in which the mature teratoma component showed LOH.
T17 1970-2048 Sentence denotes Nearly identical allelic loss patterns were seen in the three remaining cases.
T18 2049-2184 Sentence denotes In six cases analyzed, LOH patterns of each metastatic component were compared with each GCT component of the primary testicular tumor.
T19 2185-2285 Sentence denotes In all six cases, each primary and metastatic component showed an identical pattern of allelic loss.
T20 2286-2297 Sentence denotes CONCLUSION:
T21 2298-2468 Sentence denotes Our data support the common clonal origin of metastatic mature teratomas with other components of metastatic testicular GCTs and with each component of the primary tumor.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 239-266 http://purl.obolibrary.org/obo/UBERON_0035371 denotes retroperitoneal lymph nodes
PD-UBERON-AE-B_T2 609-635 http://purl.obolibrary.org/obo/UBERON_0035371 denotes retroperitoneal lymph node
PD-UBERON-AE-B_T3 255-260 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T4 625-630 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T5 255-266 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
PD-UBERON-AE-B_T6 625-635 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
PD-UBERON-AE-B_T7 962-968 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 962-968 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T2 255-260 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T3 625-630 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T4 255-266 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
PD-UBERON-AE-B_T5 625-635 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
PD-UBERON-AE-B_T6 239-266 http://purl.obolibrary.org/obo/UBERON_0035371 denotes retroperitoneal lymph nodes
PD-UBERON-AE-B_T7 609-635 http://purl.obolibrary.org/obo/UBERON_0035371 denotes retroperitoneal lymph node