PubMed:16867021
Annnotations
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
3267 | 0-13 | ChemicalEntity | denotes | Antipsychotic | MESH:D014150 |
3268 | 30-42 | ChemicalEntity | denotes | thioperamide | MESH:C052075 |
3269 | 56-67 | GeneOrGeneProduct | denotes | H3-receptor | NCBIGene:99296 |
3270 | 82-86 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
3271 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | MESH:D012559 |
3272 | 264-287 | GeneOrGeneProduct | denotes | histamine H(3)-receptor | NCBIGene:99296 |
3273 | 299-310 | ChemicalEntity | denotes | neuroleptic | MESH:D014150 |
3274 | 319-328 | DiseaseOrPhenotypicFeature | denotes | catalepsy | MESH:D002375 |
3275 | 330-341 | ChemicalEntity | denotes | apomorphine | MESH:D001058 |
3276 | 372-383 | ChemicalEntity | denotes | amphetamine | MESH:D000661 |
3277 | 416-420 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
3278 | 422-431 | DiseaseOrPhenotypicFeature | denotes | Catalepsy | MESH:D002375 |
3279 | 447-458 | ChemicalEntity | denotes | haloperidol | MESH:D006220 |
3280 | 481-492 | ChemicalEntity | denotes | apomorphine | MESH:D001058 |
3281 | 514-525 | ChemicalEntity | denotes | amphetamine | MESH:D000661 |
3282 | 622-647 | ChemicalEntity | denotes | (R)-alpha-methylhistamine | MESH:C069357 |
3283 | 649-653 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3284 | 677-689 | ChemicalEntity | denotes | thioperamide | MESH:C052075 |
3285 | 691-694 | ChemicalEntity | denotes | THP | MESH:C052075 |
3286 | 734-743 | DiseaseOrPhenotypicFeature | denotes | catalepsy | MESH:D002375 |
3287 | 763-766 | ChemicalEntity | denotes | THP | MESH:C052075 |
3288 | 810-821 | ChemicalEntity | denotes | haloperidol | MESH:D006220 |
3289 | 867-876 | DiseaseOrPhenotypicFeature | denotes | catalepsy | MESH:D002375 |
3290 | 922-926 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3291 | 968-971 | ChemicalEntity | denotes | THP | MESH:C052075 |
3292 | 989-993 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3293 | 1089-1092 | ChemicalEntity | denotes | THP | MESH:C052075 |
3294 | 1154-1165 | ChemicalEntity | denotes | amphetamine | MESH:D000661 |
3295 | 1174-1187 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | MESH:D006948 |
3296 | 1189-1192 | ChemicalEntity | denotes | THP | MESH:C052075 |
3297 | 1309-1313 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3298 | 1372-1375 | ChemicalEntity | denotes | THP | MESH:C052075 |
3299 | 1424-1435 | ChemicalEntity | denotes | apomorphine | MESH:D001058 |
3300 | 1472-1475 | ChemicalEntity | denotes | THP | MESH:C052075 |
3301 | 1530-1534 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3302 | 1536-1539 | ChemicalEntity | denotes | THP | MESH:C052075 |
3303 | 1553-1566 | ChemicalEntity | denotes | antipsychotic | MESH:D014150 |
3304 | 1596-1607 | ChemicalEntity | denotes | haloperidol | MESH:D006220 |
3305 | 1616-1625 | DiseaseOrPhenotypicFeature | denotes | catalepsy | MESH:D002375 |
3306 | 1636-1647 | ChemicalEntity | denotes | amphetamine | MESH:D000661 |
3307 | 1656-1669 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | MESH:D006948 |
3308 | 1683-1694 | ChemicalEntity | denotes | apomorphine | MESH:D001058 |
3309 | 1715-1719 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
3310 | 1737-1740 | ChemicalEntity | denotes | THP | MESH:C052075 |
3311 | 1758-1762 | ChemicalEntity | denotes | RAMH | MESH:C069357 |
3312 | 1793-1817 | GeneOrGeneProduct | denotes | histamine H(3)-receptors | NCBIGene:99296 |
3313 | 1852-1877 | ChemicalEntity | denotes | H(3)-receptor antagonists | MESH:D054828 |
3314 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | MESH:D012559 |
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-87 | Sentence | denotes | Antipsychotic-like profile of thioperamide, a selective H3-receptor antagonist in mice. |
T2 | 88-209 | Sentence | denotes | Experimental and clinical evidence points to a role of central histaminergic system in the pathogenesis of schizophrenia. |
T3 | 210-421 | Sentence | denotes | The present study was designed to study the effect of histamine H(3)-receptor ligands on neuroleptic-induced catalepsy, apomorphine-induced climbing behavior and amphetamine-induced locomotor activities in mice. |
T4 | 422-744 | Sentence | denotes | Catalepsy was induced by haloperidol (2 mg/kg p.o.), while apomorphine (1.5 mg/kg s.c.) and amphetamine (2 mg/kg s.c.) were used for studying climbing behavior and locomotor activities, respectively. (R)-alpha-methylhistamine (RAMH) (5 microg i.c.v.) and thioperamide (THP) (15 mg/kg i.p.), per se did not cause catalepsy. |
T5 | 745-894 | Sentence | denotes | Administration of THP (3.75, 7.5 and 15 mg/kg i.p.) 1 h prior to haloperidol resulted in a dose-dependent increase in the catalepsy times (P < 0.05). |
T6 | 895-988 | Sentence | denotes | However, pretreatment with RAMH significantly reversed such an effect of THP (15 mg/kg i.p.). |
T7 | 989-1150 | Sentence | denotes | RAMH per se showed significant reduction in locomotor time, distance traveled and average speed but THP (15 mg/kg i.p.) per se had no effect on these parameters. |
T8 | 1151-1290 | Sentence | denotes | On amphetamine-induced hyperactivity, THP (3.75 and 7.5 mg/kg i.p.) reduced locomotor time, distance traveled and average speed (P < 0.05). |
T9 | 1291-1394 | Sentence | denotes | Pretreatment with RAMH (5 microg i.c.v.) could partially reverse such effects of THP (3.75 mg/kg i.p.). |
T10 | 1395-1476 | Sentence | denotes | Climbing behavior induced by apomorphine was reduced in animals treated with THP. |
T11 | 1477-1535 | Sentence | denotes | Such an effect was, however, reversed in presence of RAMH. |
T12 | 1536-1720 | Sentence | denotes | THP exhibited an antipsychotic-like profile by potentiating haloperidol-induced catalepsy, reducing amphetamine-induced hyperactivity and reducing apomorphine-induced climbing in mice. |
T13 | 1721-1818 | Sentence | denotes | Such effects of THP were reversed by RAMH indicating the involvement of histamine H(3)-receptors. |
T14 | 1819-1929 | Sentence | denotes | Findings suggest a potential for H(3)-receptor antagonists in improving the refractory cases of schizophrenia. |
LitCoin-entities-OrganismTaxon-PD
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 82-86 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
T3 | 416-420 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
T5 | 1715-1719 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
T2 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 14-18 | GeneOrGeneProduct | denotes | like |
T2 | 59-67 | GeneOrGeneProduct | denotes | receptor |
T3 | 68-78 | GeneOrGeneProduct | denotes | antagonist |
T4 | 82-86 | GeneOrGeneProduct | denotes | mice |
T5 | 123-129 | GeneOrGeneProduct | denotes | points |
T6 | 279-287 | GeneOrGeneProduct | denotes | receptor |
T7 | 311-318 | GeneOrGeneProduct | denotes | induced |
T8 | 342-349 | GeneOrGeneProduct | denotes | induced |
T9 | 359-367 | GeneOrGeneProduct | denotes | behavior |
T10 | 384-391 | GeneOrGeneProduct | denotes | induced |
T11 | 402-412 | GeneOrGeneProduct | denotes | activities |
T12 | 416-420 | GeneOrGeneProduct | denotes | mice |
T13 | 436-443 | GeneOrGeneProduct | denotes | induced |
T14 | 462-464 | GeneOrGeneProduct | denotes | mg |
T15 | 498-500 | GeneOrGeneProduct | denotes | mg |
T16 | 529-531 | GeneOrGeneProduct | denotes | mg |
T17 | 573-581 | GeneOrGeneProduct | denotes | behavior |
T18 | 596-606 | GeneOrGeneProduct | denotes | activities |
T19 | 626-631 | GeneOrGeneProduct | denotes | alpha |
T20 | 700-702 | GeneOrGeneProduct | denotes | mg |
T21 | 713-716 | GeneOrGeneProduct | denotes | per |
T22 | 785-787 | GeneOrGeneProduct | denotes | mg |
T23 | 831-835 | GeneOrGeneProduct | denotes | in a |
T24 | 877-882 | GeneOrGeneProduct | denotes | times |
T25 | 976-978 | GeneOrGeneProduct | denotes | mg |
T26 | 994-997 | GeneOrGeneProduct | denotes | per |
T27 | 1043-1047 | GeneOrGeneProduct | denotes | time |
T28 | 1097-1099 | GeneOrGeneProduct | denotes | mg |
T29 | 1109-1112 | GeneOrGeneProduct | denotes | per |
T30 | 1166-1173 | GeneOrGeneProduct | denotes | induced |
T31 | 1207-1209 | GeneOrGeneProduct | denotes | mg |
T32 | 1219-1226 | GeneOrGeneProduct | denotes | reduced |
T33 | 1237-1241 | GeneOrGeneProduct | denotes | time |
T34 | 1382-1384 | GeneOrGeneProduct | denotes | mg |
T35 | 1404-1412 | GeneOrGeneProduct | denotes | behavior |
T36 | 1413-1420 | GeneOrGeneProduct | denotes | induced |
T37 | 1440-1447 | GeneOrGeneProduct | denotes | reduced |
T38 | 1567-1571 | GeneOrGeneProduct | denotes | like |
T39 | 1608-1615 | GeneOrGeneProduct | denotes | induced |
T40 | 1627-1635 | GeneOrGeneProduct | denotes | reducing |
T41 | 1648-1655 | GeneOrGeneProduct | denotes | induced |
T42 | 1674-1682 | GeneOrGeneProduct | denotes | reducing |
T43 | 1695-1702 | GeneOrGeneProduct | denotes | induced |
T44 | 1715-1719 | GeneOrGeneProduct | denotes | mice |
T45 | 1793-1817 | GeneOrGeneProduct | denotes | histamine H(3)-receptors |
T46 | 1819-1827 | GeneOrGeneProduct | denotes | Findings |
T47 | 1857-1865 | GeneOrGeneProduct | denotes | receptor |
T48 | 1866-1877 | GeneOrGeneProduct | denotes | antagonists |
T49 | 1906-1911 | GeneOrGeneProduct | denotes | cases |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 14-18 | GeneOrGeneProduct | denotes | like |
T2 | 59-67 | GeneOrGeneProduct | denotes | receptor |
T3 | 279-287 | GeneOrGeneProduct | denotes | receptor |
T4 | 359-367 | GeneOrGeneProduct | denotes | behavior |
T5 | 573-581 | GeneOrGeneProduct | denotes | behavior |
T6 | 626-631 | GeneOrGeneProduct | denotes | alpha |
T7 | 1219-1226 | GeneOrGeneProduct | denotes | reduced |
T8 | 1404-1412 | GeneOrGeneProduct | denotes | behavior |
T9 | 1440-1447 | GeneOrGeneProduct | denotes | reduced |
T10 | 1567-1571 | GeneOrGeneProduct | denotes | like |
T11 | 1793-1817 | GeneOrGeneProduct | denotes | histamine H(3)-receptors |
T12 | 1857-1865 | GeneOrGeneProduct | denotes | receptor |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
T2 | 319-328 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T3 | 422-431 | DiseaseOrPhenotypicFeature | denotes | Catalepsy | D002375 |
T4 | 734-743 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T5 | 867-876 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T6 | 1174-1187 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T7 | 1616-1625 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T8 | 1656-1669 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T9 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
T2 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 264-287 | GeneOrGeneProduct | denotes | histamine H(3)-receptor |
T2 | 626-631 | GeneOrGeneProduct | denotes | alpha |
T3 | 1793-1817 | GeneOrGeneProduct | denotes | histamine H(3)-receptors |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
T2 | 319-328 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T3 | 422-431 | DiseaseOrPhenotypicFeature | denotes | Catalepsy | D002375 |
T4 | 734-743 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T5 | 867-876 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T6 | 1174-1187 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T7 | 1616-1625 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T8 | 1656-1669 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T9 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
T2 | 319-328 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T3 | 422-431 | DiseaseOrPhenotypicFeature | denotes | Catalepsy | D002375 |
T4 | 734-743 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T5 | 867-876 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T6 | 1174-1187 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T7 | 1616-1625 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 |
T8 | 1656-1669 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
T9 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 82-86 | OrganismTaxon | denotes | mice |
T2 | 416-420 | OrganismTaxon | denotes | mice |
T3 | 1715-1719 | OrganismTaxon | denotes | mice |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 30-42 | ChemicalEntity | denotes | thioperamide | C052075 |
T2 | 56-78 | ChemicalEntity | denotes | H3-receptor antagonist | ChemicalEntity |
T3 | 264-273 | ChemicalEntity | denotes | histamine | D006632|http://purl.obolibrary.org/obo/CHEBI_58432|http://purl.obolibrary.org/obo/CHEBI_18295 |
T6 | 299-310 | ChemicalEntity | denotes | neuroleptic | ChemicalEntity |
T7 | 330-341 | ChemicalEntity | denotes | apomorphine | D001058|http://purl.obolibrary.org/obo/CHEBI_48538 |
T9 | 372-383 | ChemicalEntity | denotes | amphetamine | D000661|http://purl.obolibrary.org/obo/CHEBI_2679 |
T11 | 447-458 | ChemicalEntity | denotes | haloperidol | D006220|http://purl.obolibrary.org/obo/CHEBI_5613 |
T13 | 481-492 | ChemicalEntity | denotes | apomorphine | D001058|http://purl.obolibrary.org/obo/CHEBI_48538 |
T15 | 514-525 | ChemicalEntity | denotes | amphetamine | D000661|http://purl.obolibrary.org/obo/CHEBI_2679 |
T17 | 622-647 | ChemicalEntity | denotes | (R)-alpha-methylhistamine | http://purl.obolibrary.org/obo/CHEBI_73337 |
T18 | 649-653 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T19 | 677-689 | ChemicalEntity | denotes | thioperamide | C052075 |
T20 | 691-694 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T22 | 763-766 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T24 | 810-821 | ChemicalEntity | denotes | haloperidol | D006220|http://purl.obolibrary.org/obo/CHEBI_5613 |
T26 | 922-926 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T27 | 968-971 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T29 | 989-993 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T30 | 1089-1092 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T32 | 1154-1165 | ChemicalEntity | denotes | amphetamine | D000661|http://purl.obolibrary.org/obo/CHEBI_2679 |
T34 | 1189-1192 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T36 | 1309-1313 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T37 | 1372-1375 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T39 | 1424-1435 | ChemicalEntity | denotes | apomorphine | D001058|http://purl.obolibrary.org/obo/CHEBI_48538 |
T41 | 1472-1475 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T43 | 1530-1534 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T44 | 1536-1539 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T46 | 1596-1607 | ChemicalEntity | denotes | haloperidol | D006220|http://purl.obolibrary.org/obo/CHEBI_5613 |
T48 | 1636-1647 | ChemicalEntity | denotes | amphetamine | D000661|http://purl.obolibrary.org/obo/CHEBI_2679 |
T50 | 1683-1694 | ChemicalEntity | denotes | apomorphine | D001058|http://purl.obolibrary.org/obo/CHEBI_48538 |
T52 | 1737-1740 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 |
T54 | 1758-1762 | ChemicalEntity | denotes | RAMH | ChemicalEntity |
T55 | 1793-1802 | ChemicalEntity | denotes | histamine | D006632|http://purl.obolibrary.org/obo/CHEBI_58432|http://purl.obolibrary.org/obo/CHEBI_18295 |
T58 | 1852-1877 | ChemicalEntity | denotes | H(3)-receptor antagonists | ChemicalEntity |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T58 | 1852-1877 | ChemicalEntity | denotes | H(3)-receptor antagonists | ChemicalEntity | |
T55 | 1793-1802 | ChemicalEntity | denotes | histamine | http://purl.obolibrary.org/obo/CHEBI_18295|http://purl.obolibrary.org/obo/CHEBI_58432|D006632 | |
T54 | 1758-1762 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T52 | 1737-1740 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T50 | 1683-1694 | ChemicalEntity | denotes | apomorphine | http://purl.obolibrary.org/obo/CHEBI_48538|D001058 | |
T48 | 1636-1647 | ChemicalEntity | denotes | amphetamine | http://purl.obolibrary.org/obo/CHEBI_2679|D000661 | |
T46 | 1596-1607 | ChemicalEntity | denotes | haloperidol | http://purl.obolibrary.org/obo/CHEBI_5613|D006220 | |
T44 | 1536-1539 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T43 | 1530-1534 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T41 | 1472-1475 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T39 | 1424-1435 | ChemicalEntity | denotes | apomorphine | http://purl.obolibrary.org/obo/CHEBI_48538|D001058 | |
T37 | 1372-1375 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T36 | 1309-1313 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T34 | 1189-1192 | ChemicalEntity | denotes | THP | http://purl.obolibrary.org/obo/CHEBI_46941|C052075 | |
T32 | 1154-1165 | ChemicalEntity | denotes | amphetamine | http://purl.obolibrary.org/obo/CHEBI_2679|D000661 | |
T30 | 1089-1092 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T29 | 989-993 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T27 | 968-971 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T26 | 922-926 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T24 | 810-821 | ChemicalEntity | denotes | haloperidol | http://purl.obolibrary.org/obo/CHEBI_5613|D006220 | |
T22 | 763-766 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T20 | 691-694 | ChemicalEntity | denotes | THP | C052075|http://purl.obolibrary.org/obo/CHEBI_46941 | |
T19 | 677-689 | ChemicalEntity | denotes | thioperamide | C052075 | |
T18 | 649-653 | ChemicalEntity | denotes | RAMH | ChemicalEntity | |
T17 | 622-647 | ChemicalEntity | denotes | (R)-alpha-methylhistamine | http://purl.obolibrary.org/obo/CHEBI_73337 | |
T15 | 514-525 | ChemicalEntity | denotes | amphetamine | http://purl.obolibrary.org/obo/CHEBI_2679|D000661 | |
T13 | 481-492 | ChemicalEntity | denotes | apomorphine | http://purl.obolibrary.org/obo/CHEBI_48538|D001058 | |
T11 | 447-458 | ChemicalEntity | denotes | haloperidol | http://purl.obolibrary.org/obo/CHEBI_5613|D006220 | |
T9 | 372-383 | ChemicalEntity | denotes | amphetamine | http://purl.obolibrary.org/obo/CHEBI_2679|D000661 | |
T7 | 330-341 | ChemicalEntity | denotes | apomorphine | http://purl.obolibrary.org/obo/CHEBI_48538|D001058 | |
T6 | 299-310 | ChemicalEntity | denotes | neuroleptic | ChemicalEntity | |
T3 | 264-273 | ChemicalEntity | denotes | histamine | http://purl.obolibrary.org/obo/CHEBI_18295|http://purl.obolibrary.org/obo/CHEBI_58432|D006632 | |
T2 | 56-78 | ChemicalEntity | denotes | H3-receptor antagonist | ChemicalEntity | |
T1 | 30-42 | ChemicalEntity | denotes | thioperamide | C052075 | |
T9085 | 1793-1817 | GeneOrGeneProduct | denotes | histamine H(3)-receptors | ||
T77199 | 626-631 | GeneOrGeneProduct | denotes | alpha | ||
T97230 | 264-287 | GeneOrGeneProduct | denotes | histamine H(3)-receptor | ||
T45745 | 1915-1928 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 | |
T8 | 1656-1669 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE | |
T42132 | 1616-1625 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 | |
T31972 | 1174-1187 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE | |
T5 | 867-876 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 | |
T4 | 734-743 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 | |
T53230 | 422-431 | DiseaseOrPhenotypicFeature | denotes | Catalepsy | D002375 | |
T45840 | 319-328 | DiseaseOrPhenotypicFeature | denotes | catalepsy | D002375 | |
T30164 | 195-208 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 | |
T47111 | 1715-1719 | OrganismTaxon | denotes | mice | ||
T50167 | 416-420 | OrganismTaxon | denotes | mice | ||
T44926 | 82-86 | OrganismTaxon | denotes | mice |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 195-208 | HP_0100753 | denotes | schizophrenia |
T2 | 1174-1187 | HP_0000752 | denotes | hyperactivity |
T3 | 1656-1669 | HP_0000752 | denotes | hyperactivity |
T4 | 1915-1928 | HP_0100753 | denotes | schizophrenia |