PubMed:16838334 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PubMed/sourceid/16838334","sourcedb":"PubMed","sourceid":"16838334","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/16838334","text":"Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes.\nSeven years after a surgically resected thymoma, a female patient affected by myasthenia gravis and Good's syndrome presented with paroxysmal nocturnal hemoglobinuria (PNH). Co-culture experiments and spectratyping analyses indicated that CD8+ lymphocytes were involved in damaging hematopoietic precursors. While PNH clones have been identified in various hematological disorders, the sequential association of thymoma and PNH has been unreported so far.","tracks":[{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":174},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":175,"end":348},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":349,"end":482},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":483,"end":630},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":174},"obj":"Sentence"},{"id":"T2","span":{"begin":175,"end":348},"obj":"Sentence"},{"id":"T3","span":{"begin":349,"end":482},"obj":"Sentence"},{"id":"T4","span":{"begin":483,"end":630},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T3","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T4","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"}]},{"project":"PubCasesHPO","denotations":[{"id":"TI1","span":{"begin":0,"end":7},"obj":"HP:0100522"},{"id":"TI2","span":{"begin":20,"end":55},"obj":"HP:0004818"},{"id":"TI3","span":{"begin":116,"end":128},"obj":"HP:0002960"},{"id":"AB1","span":{"begin":306,"end":341},"obj":"HP:0004818"},{"id":"AB2","span":{"begin":587,"end":594},"obj":"HP:0100522"}],"attributes":[{"subj":"TI1","pred":"source","obj":"PubCasesHPO"},{"subj":"TI2","pred":"source","obj":"PubCasesHPO"},{"subj":"TI3","pred":"source","obj":"PubCasesHPO"},{"subj":"AB1","pred":"source","obj":"PubCasesHPO"},{"subj":"AB2","pred":"source","obj":"PubCasesHPO"}]},{"project":"PubCasesORDO","denotations":[{"id":"TI1","span":{"begin":0,"end":7},"obj":"ORDO:99867"},{"id":"TI2","span":{"begin":20,"end":55},"obj":"ORDO:447"},{"id":"AB1","span":{"begin":253,"end":270},"obj":"ORDO:589"},{"id":"AB2","span":{"begin":306,"end":341},"obj":"ORDO:447"},{"id":"AB3","span":{"begin":343,"end":346},"obj":"ORDO:447"},{"id":"AB4","span":{"begin":489,"end":492},"obj":"ORDO:447"},{"id":"AB5","span":{"begin":587,"end":594},"obj":"ORDO:99867"},{"id":"AB6","span":{"begin":599,"end":602},"obj":"ORDO:447"}],"namespaces":[{"prefix":"ORDO","uri":"http://www.orpha.net/ORDO/Orphanet_"}],"attributes":[{"subj":"TI1","pred":"source","obj":"PubCasesORDO"},{"subj":"TI2","pred":"source","obj":"PubCasesORDO"},{"subj":"AB1","pred":"source","obj":"PubCasesORDO"},{"subj":"AB2","pred":"source","obj":"PubCasesORDO"},{"subj":"AB3","pred":"source","obj":"PubCasesORDO"},{"subj":"AB4","pred":"source","obj":"PubCasesORDO"},{"subj":"AB5","pred":"source","obj":"PubCasesORDO"},{"subj":"AB6","pred":"source","obj":"PubCasesORDO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sentences","color":"#ec93bc","default":true},{"id":"PubCasesHPO","color":"#93d6ec"},{"id":"PubCasesORDO","color":"#ece893"}]}]}}