PubMed:16717433 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/16717433","sourcedb":"PubMed","sourceid":"16717433","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/16717433","text":"Interaction of subtilisin BPN' and recombinant fungal protease inhibitor F from silkworm with substituted P1 site residues.\nFungal protease inhibitor F (FPI-F) from silkworm inhibits subtilisin and fungal proteases. FPI-F mutants P(1) residues of which, Thr(29), were replaced with Glu, Phe, Gly, Leu, Met, and Arg, were prepared. The inhibitory activities of mutated FPI-F against subtilisin and other mammalian proteases indicated that FPI-F might be a specific inhibitor toward subtilisin-type protease.","tracks":[{"project":"silkworm","denotations":[{"id":"T1","span":{"begin":47,"end":74},"obj":"Gene:693072"},{"id":"T2","span":{"begin":80,"end":88},"obj":"Species:7091"},{"id":"T3","span":{"begin":124,"end":151},"obj":"Gene:693072"},{"id":"T4","span":{"begin":153,"end":158},"obj":"Gene:693072"},{"id":"T5","span":{"begin":165,"end":173},"obj":"Species:7091"},{"id":"T6","span":{"begin":216,"end":221},"obj":"Gene:693072"},{"id":"T7","span":{"begin":254,"end":257},"obj":"Chemical:MESH:D013912"},{"id":"T8","span":{"begin":282,"end":285},"obj":"Chemical:MESH:D018698"},{"id":"T9","span":{"begin":287,"end":290},"obj":"Chemical:MESH:D010649"},{"id":"T10","span":{"begin":292,"end":295},"obj":"Chemical:MESH:D005998"},{"id":"T11","span":{"begin":297,"end":300},"obj":"Chemical:MESH:D007930"},{"id":"T12","span":{"begin":302,"end":305},"obj":"Chemical:MESH:D008715"},{"id":"T13","span":{"begin":311,"end":314},"obj":"Chemical:MESH:D001120"},{"id":"T14","span":{"begin":368,"end":373},"obj":"Gene:693072"},{"id":"T15","span":{"begin":403,"end":412},"obj":"Species:9606"},{"id":"T16","span":{"begin":438,"end":443},"obj":"Gene:693072"}],"attributes":[{"subj":"T1","pred":"source","obj":"silkworm"},{"subj":"T2","pred":"source","obj":"silkworm"},{"subj":"T3","pred":"source","obj":"silkworm"},{"subj":"T4","pred":"source","obj":"silkworm"},{"subj":"T5","pred":"source","obj":"silkworm"},{"subj":"T6","pred":"source","obj":"silkworm"},{"subj":"T7","pred":"source","obj":"silkworm"},{"subj":"T8","pred":"source","obj":"silkworm"},{"subj":"T9","pred":"source","obj":"silkworm"},{"subj":"T10","pred":"source","obj":"silkworm"},{"subj":"T11","pred":"source","obj":"silkworm"},{"subj":"T12","pred":"source","obj":"silkworm"},{"subj":"T13","pred":"source","obj":"silkworm"},{"subj":"T14","pred":"source","obj":"silkworm"},{"subj":"T15","pred":"source","obj":"silkworm"},{"subj":"T16","pred":"source","obj":"silkworm"}]},{"project":"silkwormbase","denotations":[{"id":"T1","span":{"begin":47,"end":74},"obj":"Gene:693072"},{"id":"T10","span":{"begin":292,"end":295},"obj":"Chemical:MESH:D005998"},{"id":"T11","span":{"begin":297,"end":300},"obj":"Chemical:MESH:D007930"},{"id":"T12","span":{"begin":302,"end":305},"obj":"Chemical:MESH:D008715"},{"id":"T13","span":{"begin":311,"end":314},"obj":"Chemical:MESH:D001120"},{"id":"T14","span":{"begin":368,"end":373},"obj":"Gene:693072"},{"id":"T15","span":{"begin":403,"end":412},"obj":"Species:9606"},{"id":"T16","span":{"begin":438,"end":443},"obj":"Gene:693072"},{"id":"T2","span":{"begin":80,"end":88},"obj":"Species:7091"},{"id":"T3","span":{"begin":124,"end":151},"obj":"Gene:693072"},{"id":"T4","span":{"begin":153,"end":158},"obj":"Gene:693072"},{"id":"T5","span":{"begin":165,"end":173},"obj":"Species:7091"},{"id":"T6","span":{"begin":216,"end":221},"obj":"Gene:693072"},{"id":"T7","span":{"begin":254,"end":257},"obj":"Chemical:MESH:D013912"},{"id":"T8","span":{"begin":282,"end":285},"obj":"Chemical:MESH:D018698"},{"id":"T9","span":{"begin":287,"end":290},"obj":"Chemical:MESH:D010649"}],"attributes":[{"subj":"T1","pred":"source","obj":"silkwormbase"},{"subj":"T10","pred":"source","obj":"silkwormbase"},{"subj":"T11","pred":"source","obj":"silkwormbase"},{"subj":"T12","pred":"source","obj":"silkwormbase"},{"subj":"T13","pred":"source","obj":"silkwormbase"},{"subj":"T14","pred":"source","obj":"silkwormbase"},{"subj":"T15","pred":"source","obj":"silkwormbase"},{"subj":"T16","pred":"source","obj":"silkwormbase"},{"subj":"T2","pred":"source","obj":"silkwormbase"},{"subj":"T3","pred":"source","obj":"silkwormbase"},{"subj":"T4","pred":"source","obj":"silkwormbase"},{"subj":"T5","pred":"source","obj":"silkwormbase"},{"subj":"T6","pred":"source","obj":"silkwormbase"},{"subj":"T7","pred":"source","obj":"silkwormbase"},{"subj":"T8","pred":"source","obj":"silkwormbase"},{"subj":"T9","pred":"source","obj":"silkwormbase"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"silkworm","color":"#93ecbf","default":true},{"id":"silkwormbase","color":"#eca593"}]}]}}