PubMed:16680342
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/16680342","sourcedb":"PubMed","sourceid":"16680342","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/16680342","text":"Coffee and gastric cancer: systematic review and meta-analysis.\nWe systematically reviewed the literature on the association between coffee consumption and gastric cancer and performed a meta-analysis of the results. Published cohort and case-control studies were identified in PubMed and reference lists. Random effects meta-analysis was used to pool effects from 23 studies, and heterogeneity was explored by stratification and meta-regression. The odds ratio (OR) for the overall association between coffee and gastric cancer (highest vs. lowest category of exposure) was 0.97 (95%CI: 0.86-1.09), similar for cohort (OR = 1.02; 95%CI: 0.76-1.37) and case-control studies (population-based: OR = 0.90; 95%CI: 0.70-1.15; hospital-based: OR = 0.97; 95%CI: 0.83-1.13). The OR was 1.26 (95%CI: 1.02-1.57) when considering five studies conducted in the USA, 0.97 (95%CI: 0.82-1.14) for the five Japanese studies, 0.98 (95%CI: 0.81-1.17) for the six studies from Europe, and 0.64 (95%CI: 0.47-0.86) for the two studies from South America. In this meta-analysis we found no adverse effect of coffee associated with gastric cancer. Knowledge on the level of exposure to different coffee constituents may provide a deeper understanding of this reassuring result and the real role of coffee on cancer risk.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":156,"end":170},"obj":"HP_0012126"},{"id":"T2","span":{"begin":164,"end":170},"obj":"HP_0002664"},{"id":"T3","span":{"begin":514,"end":528},"obj":"HP_0012126"},{"id":"T4","span":{"begin":522,"end":528},"obj":"HP_0002664"},{"id":"T5","span":{"begin":1110,"end":1124},"obj":"HP_0012126"},{"id":"T6","span":{"begin":1118,"end":1124},"obj":"HP_0002664"},{"id":"T7","span":{"begin":1286,"end":1292},"obj":"HP_0002664"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"}]},{"project":"LitCoin-PubTator-for-Tuning","denotations":[{"id":"1","span":{"begin":11,"end":25},"obj":"DiseaseOrPhenotypicFeature"},{"id":"6","span":{"begin":156,"end":170},"obj":"DiseaseOrPhenotypicFeature"},{"id":"7","span":{"begin":514,"end":528},"obj":"DiseaseOrPhenotypicFeature"},{"id":"8","span":{"begin":1110,"end":1124},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9","span":{"begin":1286,"end":1292},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A8","pred":"tao:has_database_id","subj":"8","obj":"MESH:D013274"},{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"MESH:D009369"},{"id":"A6","pred":"tao:has_database_id","subj":"6","obj":"MESH:D013274"},{"id":"A1","pred":"tao:has_database_id","subj":"1","obj":"MESH:D013274"},{"id":"A7","pred":"tao:has_database_id","subj":"7","obj":"MESH:D013274"},{"subj":"1","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"6","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"7","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"8","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"9","pred":"source","obj":"LitCoin-PubTator-for-Tuning"}]},{"project":"LitCoin-Disease-Tuning-1","denotations":[{"id":"T1","span":{"begin":11,"end":25},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":156,"end":170},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":514,"end":528},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1110,"end":1124},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1286,"end":1292},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D013274"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D009369"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D013274"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D013274"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D013274"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-Tuning-1"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-Tuning-1"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-Tuning-1"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-Tuning-1"},{"subj":"T5","pred":"source","obj":"LitCoin-Disease-Tuning-1"}]},{"project":"LitEisuke","denotations":[{"id":"T1","span":{"begin":11,"end":25},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":156,"end":170},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":514,"end":528},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1110,"end":1124},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1286,"end":1292},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A3","pred":"#label","subj":"T3","obj":"D013274"},{"id":"A1","pred":"#label","subj":"T1","obj":"D013274"},{"id":"A2","pred":"#label","subj":"T2","obj":"D013274"},{"id":"A4","pred":"#label","subj":"T4","obj":"D013274"},{"id":"A5","pred":"#label","subj":"T5","obj":"D009369"},{"subj":"T1","pred":"source","obj":"LitEisuke"},{"subj":"T2","pred":"source","obj":"LitEisuke"},{"subj":"T3","pred":"source","obj":"LitEisuke"},{"subj":"T4","pred":"source","obj":"LitEisuke"},{"subj":"T5","pred":"source","obj":"LitEisuke"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#ecea93","default":true},{"id":"LitCoin-PubTator-for-Tuning","color":"#d093ec"},{"id":"LitCoin-Disease-Tuning-1","color":"#93ecb6"},{"id":"LitEisuke","color":"#ec9c93"}]}]}}