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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-146 Sentence denotes Tumor thymidylate synthase 1494del6 genotype as a prognostic factor in colorectal cancer patients receiving fluorouracil-based adjuvant treatment.
T2 147-155 Sentence denotes PURPOSE:
T3 156-385 Sentence denotes The purpose of this study was to analyze the value of germline and tumor thymidylate synthase (TS) genotyping as a prognostic marker in a series of colorectal cancer patients receiving adjuvant fluorouracil (FU) -based treatment.
T4 386-407 Sentence denotes PATIENTS AND METHODS:
T5 408-557 Sentence denotes One hundred twenty-nine colorectal cancer patients homogeneously treated with FU plus levamisole or leucovorin in the adjuvant setting were included.
T6 558-714 Sentence denotes TS enhancer region, 3R G > C single nucleotide polymorphism (SNP), and TS 1494del6 polymorphisms were assessed in both fresh-frozen normal mucosa and tumor.
T7 715-843 Sentence denotes Mutational analyses of TS and allelic imbalances were studied in all primary tumors and in 18 additional metachronic metastases.
T8 844-919 Sentence denotes TS protein immunostaining was assessed in an expanded series of 214 tumors.
T9 920-999 Sentence denotes Multivariate Cox models were adjusted for stage, differentiation, and location.
T10 1000-1008 Sentence denotes RESULTS:
T11 1009-1210 Sentence denotes Tumor genotyping (frequency of allelic loss, 26%) showed that the 3R/3R genotype was associated with a better outcome (hazard ratio [HR] = 0.38; 95% CI, 0.16 to 0.93; P = .020 for the recessive model).
T12 1211-1270 Sentence denotes 3R G > C SNP genotyping did not add prognostic information.
T13 1271-1452 Sentence denotes Tumor TS 1494del6 allele (frequency of allelic loss, 36%) was protective (for each allele with the deletion, based on an additive model, HR = 0.42; 95% CI, 0.22 to 0.82; P = .0034).
T14 1453-1713 Sentence denotes Both polymorphisms were in strong linkage disequilibrium (D' = 0.71, P < .001), and the 3R/-6 base pair (bp) haplotype showed a significant overall survival benefit compared with the most prevalent haplotype 2R/+6bp (HR = 0.42; 95% CI, 0.20 to 0.85; P = .017).
T15 1714-1780 Sentence denotes No TS point mutation was detected in primary tumors or metastases.
T16 1781-1873 Sentence denotes TS protein immunostaining was not associated with survival or any of the genotypes analyzed.
T17 1874-1885 Sentence denotes CONCLUSION:
T18 1886-2001 Sentence denotes Tumor TS 1494del6 genotype may be a prognostic factor in FU-based adjuvant treatment of colorectal cancer patients.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
2883 0-5 DiseaseOrPhenotypicFeature denotes Tumor MESH:D009369
2884 6-26 GeneOrGeneProduct denotes thymidylate synthase NCBIGene:7298
2885 27-35 SequenceVariant denotes 1494del6 c|DEL|1494|6
2886 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer MESH:D015179
2887 89-97 OrganismTaxon denotes patients NCBITaxon:9606
2888 108-120 ChemicalEntity denotes fluorouracil MESH:D005472
2889 223-228 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
2890 229-249 GeneOrGeneProduct denotes thymidylate synthase NCBIGene:7298
2891 251-253 GeneOrGeneProduct denotes TS NCBIGene:7298
2892 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer MESH:D015179
2893 322-330 OrganismTaxon denotes patients NCBITaxon:9606
2894 350-362 ChemicalEntity denotes fluorouracil MESH:D005472
2895 364-366 ChemicalEntity denotes FU MESH:D005472
2896 386-394 OrganismTaxon denotes PATIENTS NCBITaxon:9606
2897 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer MESH:D015179
2898 450-458 OrganismTaxon denotes patients NCBITaxon:9606
2899 486-488 ChemicalEntity denotes FU MESH:D005472
2900 494-504 ChemicalEntity denotes levamisole MESH:D007978
2901 508-518 ChemicalEntity denotes leucovorin MESH:D002955
2902 558-560 GeneOrGeneProduct denotes TS NCBIGene:7298
2903 581-586 SequenceVariant denotes G > C c|SUB|G||C
2904 629-631 GeneOrGeneProduct denotes TS NCBIGene:7298
2905 632-640 SequenceVariant denotes 1494del6 c|DEL|1494|6
2906 708-713 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
2907 738-740 GeneOrGeneProduct denotes TS NCBIGene:7298
2908 792-798 DiseaseOrPhenotypicFeature denotes tumors MESH:D009369
2909 832-842 DiseaseOrPhenotypicFeature denotes metastases MESH:D009362
2910 844-846 GeneOrGeneProduct denotes TS NCBIGene:7298
2911 912-918 DiseaseOrPhenotypicFeature denotes tumors MESH:D009369
2912 1009-1014 DiseaseOrPhenotypicFeature denotes Tumor MESH:D009369
2913 1214-1219 SequenceVariant denotes G > C c|SUB|G||C
2914 1271-1276 DiseaseOrPhenotypicFeature denotes Tumor MESH:D009369
2915 1277-1279 GeneOrGeneProduct denotes TS NCBIGene:7298
2916 1280-1288 SequenceVariant denotes 1494del6 c|DEL|1494|6
2917 1717-1719 GeneOrGeneProduct denotes TS NCBIGene:7298
2918 1759-1765 DiseaseOrPhenotypicFeature denotes tumors MESH:D009369
2919 1769-1779 DiseaseOrPhenotypicFeature denotes metastases MESH:D009362
2920 1781-1783 GeneOrGeneProduct denotes TS NCBIGene:7298
2921 1886-1891 DiseaseOrPhenotypicFeature denotes Tumor MESH:D009369
2922 1892-1894 GeneOrGeneProduct denotes TS NCBIGene:7298
2923 1895-1903 SequenceVariant denotes 1494del6 c|DEL|1494|6
2924 1943-1945 ChemicalEntity denotes FU MESH:D005472
2925 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer MESH:D015179
2926 1992-2000 OrganismTaxon denotes patients NCBITaxon:9606

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer 0005575
T2 82-88 DiseaseOrPhenotypicFeature denotes cancer 0004992
T3 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer 0005575
T4 315-321 DiseaseOrPhenotypicFeature denotes cancer 0004992
T5 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer 0005575
T6 443-449 DiseaseOrPhenotypicFeature denotes cancer 0004992
T7 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer 0005575
T8 1985-1991 DiseaseOrPhenotypicFeature denotes cancer 0004992

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 27-35 SequenceVariant denotes 1494del6
T2 632-640 SequenceVariant denotes 1494del6
T3 1280-1288 SequenceVariant denotes 1494del6
T4 1895-1903 SequenceVariant denotes 1494del6

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 6-26 GeneOrGeneProduct denotes thymidylate synthase
T2 61-67 GeneOrGeneProduct denotes factor
T3 229-249 GeneOrGeneProduct denotes thymidylate synthase
T4 251-253 GeneOrGeneProduct denotes TS
T5 558-560 GeneOrGeneProduct denotes TS
T6 629-631 GeneOrGeneProduct denotes TS
T7 738-740 GeneOrGeneProduct denotes TS
T8 844-846 GeneOrGeneProduct denotes TS
T9 847-854 GeneOrGeneProduct denotes protein
T10 889-897 GeneOrGeneProduct denotes expanded
T11 1027-1036 GeneOrGeneProduct denotes frequency
T12 1277-1279 GeneOrGeneProduct denotes TS
T13 1297-1306 GeneOrGeneProduct denotes frequency
T14 1717-1719 GeneOrGeneProduct denotes TS
T15 1781-1783 GeneOrGeneProduct denotes TS
T16 1784-1791 GeneOrGeneProduct denotes protein
T17 1892-1894 GeneOrGeneProduct denotes TS
T18 1933-1939 GeneOrGeneProduct denotes factor

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-5 GeneOrGeneProduct denotes Tumor
T2 6-26 GeneOrGeneProduct denotes thymidylate synthase
T3 61-67 GeneOrGeneProduct denotes factor
T4 121-126 GeneOrGeneProduct denotes based
T5 201-206 GeneOrGeneProduct denotes value
T6 223-228 GeneOrGeneProduct denotes tumor
T7 229-249 GeneOrGeneProduct denotes thymidylate synthase
T8 251-253 GeneOrGeneProduct denotes TS
T9 289-293 GeneOrGeneProduct denotes in a
T10 369-374 GeneOrGeneProduct denotes based
T11 395-406 GeneOrGeneProduct denotes AND METHODS
T12 427-431 GeneOrGeneProduct denotes nine
T13 558-560 GeneOrGeneProduct denotes TS
T14 581-586 GeneOrGeneProduct denotes G > C
T15 629-631 GeneOrGeneProduct denotes TS
T16 708-713 GeneOrGeneProduct denotes tumor
T17 715-725 GeneOrGeneProduct denotes Mutational
T18 738-740 GeneOrGeneProduct denotes TS
T19 780-783 GeneOrGeneProduct denotes all
T20 792-798 GeneOrGeneProduct denotes tumors
T21 803-808 GeneOrGeneProduct denotes in 18
T22 844-846 GeneOrGeneProduct denotes TS
T23 847-854 GeneOrGeneProduct denotes protein
T24 889-897 GeneOrGeneProduct denotes expanded
T25 912-918 GeneOrGeneProduct denotes tumors
T26 1009-1014 GeneOrGeneProduct denotes Tumor
T27 1027-1036 GeneOrGeneProduct denotes frequency
T28 1176-1184 GeneOrGeneProduct denotes P = .020
T29 1214-1219 GeneOrGeneProduct denotes G > C
T30 1271-1276 GeneOrGeneProduct denotes Tumor
T31 1277-1279 GeneOrGeneProduct denotes TS
T32 1297-1306 GeneOrGeneProduct denotes frequency
T33 1380-1385 GeneOrGeneProduct denotes based
T34 1547-1551 GeneOrGeneProduct denotes base
T35 1552-1556 GeneOrGeneProduct denotes pair
T36 1717-1719 GeneOrGeneProduct denotes TS
T37 1720-1725 GeneOrGeneProduct denotes point
T38 1726-1734 GeneOrGeneProduct denotes mutation
T39 1759-1765 GeneOrGeneProduct denotes tumors
T40 1781-1783 GeneOrGeneProduct denotes TS
T41 1784-1791 GeneOrGeneProduct denotes protein
T42 1886-1891 GeneOrGeneProduct denotes Tumor
T43 1892-1894 GeneOrGeneProduct denotes TS
T44 1913-1921 GeneOrGeneProduct denotes may be a
T45 1933-1939 GeneOrGeneProduct denotes factor
T46 1946-1951 GeneOrGeneProduct denotes based

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 0-5 DiseaseOrPhenotypicFeature denotes Tumor D009369
T2 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T3 223-228 DiseaseOrPhenotypicFeature denotes tumor D009369
T4 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T5 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T6 708-713 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 792-798 DiseaseOrPhenotypicFeature denotes tumors D009369
T8 832-842 DiseaseOrPhenotypicFeature denotes metastases D009362
T9 912-918 DiseaseOrPhenotypicFeature denotes tumors D009369
T10 1009-1014 DiseaseOrPhenotypicFeature denotes Tumor D009369
T11 1271-1276 DiseaseOrPhenotypicFeature denotes Tumor D009369
T12 1759-1765 DiseaseOrPhenotypicFeature denotes tumors D009369
T13 1769-1779 DiseaseOrPhenotypicFeature denotes metastases D009362
T14 1886-1891 DiseaseOrPhenotypicFeature denotes Tumor D009369
T15 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 6-26 GeneOrGeneProduct denotes thymidylate synthase
T2 229-249 GeneOrGeneProduct denotes thymidylate synthase
T3 251-253 GeneOrGeneProduct denotes TS
T4 558-560 GeneOrGeneProduct denotes TS
T5 629-631 GeneOrGeneProduct denotes TS
T6 738-740 GeneOrGeneProduct denotes TS
T7 844-846 GeneOrGeneProduct denotes TS
T8 1277-1279 GeneOrGeneProduct denotes TS
T9 1717-1719 GeneOrGeneProduct denotes TS
T10 1781-1783 GeneOrGeneProduct denotes TS
T11 1892-1894 GeneOrGeneProduct denotes TS

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer 0024331|0005575
T3 223-228 DiseaseOrPhenotypicFeature denotes tumor 0005070
T4 251-253 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T6 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer 0024331|0005575
T8 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer 0024331|0005575
T10 558-560 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T12 629-631 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T14 708-713 DiseaseOrPhenotypicFeature denotes tumor 0005070
T15 738-740 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T17 844-846 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T19 1277-1279 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T21 1717-1719 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T23 1781-1783 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T25 1892-1894 DiseaseOrPhenotypicFeature denotes TS 0016455|0010979
T27 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer 0024331|0005575

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 0-5 DiseaseOrPhenotypicFeature denotes Tumor D009369
T2 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T3 223-228 DiseaseOrPhenotypicFeature denotes tumor D009369
T4 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T5 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T6 708-713 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 792-798 DiseaseOrPhenotypicFeature denotes tumors DISEASE|D009369
T9 832-842 DiseaseOrPhenotypicFeature denotes metastases D009362
T10 912-918 DiseaseOrPhenotypicFeature denotes tumors DISEASE|D009369
T12 1009-1014 DiseaseOrPhenotypicFeature denotes Tumor D009369
T13 1271-1276 DiseaseOrPhenotypicFeature denotes Tumor D009369
T14 1759-1765 DiseaseOrPhenotypicFeature denotes tumors D009369
T15 1769-1779 DiseaseOrPhenotypicFeature denotes metastases D009362
T16 1886-1891 DiseaseOrPhenotypicFeature denotes Tumor D009369
T17 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 0-5 DiseaseOrPhenotypicFeature denotes Tumor D009369
T2 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T3 223-228 DiseaseOrPhenotypicFeature denotes tumor D009369
T4 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T5 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T6 708-713 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 792-798 DiseaseOrPhenotypicFeature denotes tumors D009369
T8 832-842 DiseaseOrPhenotypicFeature denotes metastases D009362
T9 912-918 DiseaseOrPhenotypicFeature denotes tumors D009369
T10 1009-1014 DiseaseOrPhenotypicFeature denotes Tumor D009369
T11 1271-1276 DiseaseOrPhenotypicFeature denotes Tumor D009369
T12 1759-1765 DiseaseOrPhenotypicFeature denotes tumors D009369
T13 1769-1779 DiseaseOrPhenotypicFeature denotes metastases D009362
T14 1886-1891 DiseaseOrPhenotypicFeature denotes Tumor D009369
T15 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 6-26 ChemicalEntity denotes thymidylate synthase D013940
T2 108-120 ChemicalEntity denotes fluorouracil D005472|http://purl.obolibrary.org/obo/CHEBI_46345
T4 229-249 ChemicalEntity denotes thymidylate synthase D013940
T5 251-253 ChemicalEntity denotes TS D013940
T6 350-362 ChemicalEntity denotes fluorouracil D005472|http://purl.obolibrary.org/obo/CHEBI_46345
T8 364-366 ChemicalEntity denotes FU D005472
T9 486-488 ChemicalEntity denotes FU D005472
T10 494-504 ChemicalEntity denotes levamisole D007978|http://purl.obolibrary.org/obo/CHEBI_6432
T12 508-518 ChemicalEntity denotes leucovorin D002955
T13 558-560 ChemicalEntity denotes TS D013940
T14 629-631 ChemicalEntity denotes TS D013940
T15 738-740 ChemicalEntity denotes TS D013940
T16 844-846 ChemicalEntity denotes TS D013940
T17 1277-1279 ChemicalEntity denotes TS D013940
T18 1717-1719 ChemicalEntity denotes TS D013940
T19 1781-1783 ChemicalEntity denotes TS D013940
T20 1892-1894 ChemicalEntity denotes TS D013940
T21 1943-1945 ChemicalEntity denotes FU D005472

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 89-97 OrganismTaxon denotes patients
T2 322-330 OrganismTaxon denotes patients
T3 450-458 OrganismTaxon denotes patients
T4 1992-2000 OrganismTaxon denotes patients

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T21 1943-1945 ChemicalEntity denotes FU D005472
T20 1892-1894 ChemicalEntity denotes TS D013940
T19 1781-1783 ChemicalEntity denotes TS D013940
T18 1717-1719 ChemicalEntity denotes TS D013940
T17 1277-1279 ChemicalEntity denotes TS D013940
T16 844-846 ChemicalEntity denotes TS D013940
T15 738-740 ChemicalEntity denotes TS D013940
T14 629-631 ChemicalEntity denotes TS D013940
T13 558-560 ChemicalEntity denotes TS D013940
T12 508-518 ChemicalEntity denotes leucovorin D002955
T10 494-504 ChemicalEntity denotes levamisole http://purl.obolibrary.org/obo/CHEBI_6432|D007978
T9 486-488 ChemicalEntity denotes FU D005472
T8 364-366 ChemicalEntity denotes FU D005472
T6 350-362 ChemicalEntity denotes fluorouracil http://purl.obolibrary.org/obo/CHEBI_46345|D005472
T5 251-253 ChemicalEntity denotes TS D013940
T4 229-249 ChemicalEntity denotes thymidylate synthase D013940
T2 108-120 ChemicalEntity denotes fluorouracil http://purl.obolibrary.org/obo/CHEBI_46345|D005472
T1 6-26 ChemicalEntity denotes thymidylate synthase D013940
T11 1892-1894 GeneOrGeneProduct denotes TS
T75100 1781-1783 GeneOrGeneProduct denotes TS
T10468 1717-1719 GeneOrGeneProduct denotes TS
T61565 1277-1279 GeneOrGeneProduct denotes TS
T7 844-846 GeneOrGeneProduct denotes TS
T82298 738-740 GeneOrGeneProduct denotes TS
T97072 629-631 GeneOrGeneProduct denotes TS
T45520 558-560 GeneOrGeneProduct denotes TS
T3 251-253 GeneOrGeneProduct denotes TS
T89156 229-249 GeneOrGeneProduct denotes thymidylate synthase
T3816 6-26 GeneOrGeneProduct denotes thymidylate synthase
T52260 1974-1991 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T75272 1886-1891 DiseaseOrPhenotypicFeature denotes Tumor D009369
T25332 1769-1779 DiseaseOrPhenotypicFeature denotes metastases D009362
T23696 1759-1765 DiseaseOrPhenotypicFeature denotes tumors D009369
T61220 1271-1276 DiseaseOrPhenotypicFeature denotes Tumor D009369
T59 1009-1014 DiseaseOrPhenotypicFeature denotes Tumor D009369
T25142 912-918 DiseaseOrPhenotypicFeature denotes tumors D009369
T82527 832-842 DiseaseOrPhenotypicFeature denotes metastases D009362
T45078 792-798 DiseaseOrPhenotypicFeature denotes tumors D009369
T6600 708-713 DiseaseOrPhenotypicFeature denotes tumor D009369
T89114 432-449 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T11093 304-321 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T21034 223-228 DiseaseOrPhenotypicFeature denotes tumor D009369
T72992 71-88 DiseaseOrPhenotypicFeature denotes colorectal cancer D015179
T58484 0-5 DiseaseOrPhenotypicFeature denotes Tumor D009369
T3402 1992-2000 OrganismTaxon denotes patients
T33755 450-458 OrganismTaxon denotes patients
T1525 322-330 OrganismTaxon denotes patients
T46258 89-97 OrganismTaxon denotes patients
T89547 1895-1903 SequenceVariant denotes 1494del6
T86536 1280-1288 SequenceVariant denotes 1494del6
T55846 632-640 SequenceVariant denotes 1494del6
T8135 27-35 SequenceVariant denotes 1494del6

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 223-228 HP_0002664 denotes tumor
T2 315-321 HP_0002664 denotes cancer

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
16575011-0#6#26#gene7298 6-26 gene7298 denotes thymidylate synthase
16575011-0#71#88#diseaseC0009402 71-88 diseaseC0009402 denotes colorectal cancer
16575011-0#71#88#diseaseC1527249 71-88 diseaseC1527249 denotes colorectal cancer
16575011-11#3#5#gene7298 1717-1719 gene7298 denotes TS
16575011-11#55#65#diseaseC0027627 1769-1779 diseaseC0027627 denotes metastases
6#26#gene729871#88#diseaseC0009402 16575011-0#6#26#gene7298 16575011-0#71#88#diseaseC0009402 associated_with thymidylate synthase,colorectal cancer
6#26#gene729871#88#diseaseC1527249 16575011-0#6#26#gene7298 16575011-0#71#88#diseaseC1527249 associated_with thymidylate synthase,colorectal cancer
3#5#gene729855#65#diseaseC0027627 16575011-11#3#5#gene7298 16575011-11#55#65#diseaseC0027627 associated_with TS,metastases

tmVarCorpus

Id Subject Object Predicate Lexical cue
T1 27-35 DNAMutation:|DEL|1494|6 denotes 1494del6
T2 581-586 DNAMutation:|SUB|G||C denotes G > C
T3 632-640 DNAMutation:|DEL|1494|6 denotes 1494del6
T4 1214-1219 DNAMutation:|SUB|G||C denotes G > C
T5 1280-1288 DNAMutation:|DEL|1494|6 denotes 1494del6
T6 1895-1903 DNAMutation:|DEL|1494|6 denotes 1494del6

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1717-1719 gene:7298 denotes TS
T1 1769-1779 disease:C0027627 denotes metastases
T2 1717-1719 gene:7298 denotes TS
T3 1769-1779 disease:C2939419 denotes metastases
R1 T0 T1 associated_with TS,metastases
R2 T2 T3 associated_with TS,metastases