> top > docs > PubMed:164448 > annotations

PubMed:164448 JSONTXT

Annnotations TAB JSON ListView MergeView

Test-Species-PubTator

Id Subject Object Predicate Lexical cue resolved_to
3 10-32 Chemical denotes Ricinus communis toxin -
4 36-72 Chemical denotes cyclic adenosine 3':5'-monophosphate -
5 87-110 CellLine denotes Yoshida ascites sarcoma CVCL:4U54
35 118-134 Chemical denotes Prostaglandin E1 MESH:D000527
36 170-206 Chemical denotes cyclic adenosine 3':5'-monophosphate -
37 208-218 Chemical denotes cyclic AMP -
38 243-266 Disease denotes Yoshida ascites sarcoma MESH:D012517
39 268-270 CellLine denotes YS CVCL:4U54
40 302-324 Chemical denotes Ricinus communis toxin -
41 326-334 Chemical denotes RC-toxin -
42 375-391 Chemical denotes prostaglandin E1 MESH:D000527
43 415-425 Chemical denotes cyclic AMP -
44 433-435 CellLine denotes YS CVCL:4U54
45 464-472 Chemical denotes RC-toxin -
46 547-554 Chemical denotes lactose MESH:D007785
47 560-568 Chemical denotes RC-toxin -
48 595-603 Chemical denotes RC-toxin -
49 628-638 Chemical denotes cyclic AMP -
50 698-706 Chemical denotes RC-toxin -
51 787-797 Chemical denotes cyclic AMP -
52 858-868 Chemical denotes cyclic AMP -
53 912-940 Chemical denotes cyclic AMP phosphodiesterase -
54 968-970 CellLine denotes YS CVCL:4U54
55 982-990 Chemical denotes RC-toxin -
56 1110-1113 Chemical denotes ATP MESH:D000255
57 1215-1218 Chemical denotes ATP MESH:D000255
58 1294-1297 Chemical denotes ATP MESH:D000255
59 1313-1321 Chemical denotes RC-toxin -
60 1356-1360 Chemical denotes Mg2+ -
61 1487-1497 Chemical denotes cyclic AMP -
62 1501-1503 CellLine denotes YS CVCL:4U54
63 1521-1529 Chemical denotes RC-toxin -

Test-Species-PubDictionaries

Id Subject Object Predicate Lexical cue db_id
T1 10-26 OrganismTaxon denotes Ricinus communis 3988
T2 302-318 OrganismTaxon denotes Ricinus communis 3988

Test-Species-PubDictionaries-PubMedBERT

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Species denotes Ricinus communis 3988
T2 87-94 Species denotes Yoshida 1364882
T3 140-143 Species denotes mug 1311525
T4 243-250 Species denotes Yoshida 1364882
T5 302-318 Species denotes Ricinus communis 3988
T6 326-334 Species denotes RC-toxin 3988
T7 464-472 Species denotes RC-toxin 3988
T8 478-481 Species denotes mug 1311525
T9 560-568 Species denotes RC-toxin 3988
T10 595-603 Species denotes RC-toxin 3988
T11 698-706 Species denotes RC-toxin 3988
T12 886-892 Species denotes change 1766596
T13 982-990 Species denotes RC-toxin 3988
T14 1138-1144 Species denotes little 35885
T15 1313-1321 Species denotes RC-toxin 3988
T16 1521-1529 Species denotes RC-toxin 3988
T17 1559-1569 Species denotes the change 1766596

sentences

Id Subject Object Predicate Lexical cue
T1 0-117 Sentence denotes Effect of Ricinus communis toxin on cyclic adenosine 3':5'-monophosphate metabolism in Yoshida ascites sarcoma cells.
T2 118-296 Sentence denotes Prostaglandin E1 (2.5 mug/ml) enhanced the level of cyclic adenosine 3':5'-monophosphate (cyclic AMP) three to four times in Yoshida ascites sarcoma (YS) cells cultured in vitro.
T3 297-460 Sentence denotes When Ricinus communis toxin (RC-toxin) was added 30 min after the addition of prostaglandin E1, the enhanced level of cyclic AMP in the YS cells decreased rapidly.
T4 461-526 Sentence denotes Of RC-toxin, 0.2 mug/ml was enough to produce the maximum effect.
T5 527-653 Sentence denotes By addition of 5 mM lactose with RC-toxin, approximately 60% of the RC-toxin effect on the levels of cyclic AMP was abolished.
T6 654-804 Sentence denotes This indicates that the specific binding of RC-toxin on the surface membrane is largely responsible for the observed decrease of the cyclic AMP level.
T7 805-941 Sentence denotes The toxin treatment did not induce either leakage of cyclic AMP from the cell or change in the activity of cyclic AMP phosphodiesterase.
T8 942-1114 Sentence denotes However, the treatment of YS cells with RC-toxin caused a decrease of adenylate cyclase activity when the activity was measured at a substrate concentration of 0.15 mM ATP.
T9 1115-1242 Sentence denotes In contrast, there was little difference with the control when the activity was assayed at a higher ATP concentration, 0.24 mM.
T10 1243-1428 Sentence denotes It was found that the K-m of adenylate cyclase for ATP was changed by RC-toxin from 0.1 to 0.25 mM, and that the Mg2+ activation of the enzyme observable in untreated cells disappeared.
T11 1429-1611 Sentence denotes These results suggested that the decrease in the level of cyclic AMP in YS cells induced by RC-toxin can be explained in terms of the change in K-m of the adenylate cyclase activity.
T1 0-117 Sentence denotes Effect of Ricinus communis toxin on cyclic adenosine 3':5'-monophosphate metabolism in Yoshida ascites sarcoma cells.
T2 118-296 Sentence denotes Prostaglandin E1 (2.5 mug/ml) enhanced the level of cyclic adenosine 3':5'-monophosphate (cyclic AMP) three to four times in Yoshida ascites sarcoma (YS) cells cultured in vitro.
T3 297-460 Sentence denotes When Ricinus communis toxin (RC-toxin) was added 30 min after the addition of prostaglandin E1, the enhanced level of cyclic AMP in the YS cells decreased rapidly.
T4 461-526 Sentence denotes Of RC-toxin, 0.2 mug/ml was enough to produce the maximum effect.
T5 527-653 Sentence denotes By addition of 5 mM lactose with RC-toxin, approximately 60% of the RC-toxin effect on the levels of cyclic AMP was abolished.
T6 654-804 Sentence denotes This indicates that the specific binding of RC-toxin on the surface membrane is largely responsible for the observed decrease of the cyclic AMP level.
T7 805-941 Sentence denotes The toxin treatment did not induce either leakage of cyclic AMP from the cell or change in the activity of cyclic AMP phosphodiesterase.
T8 942-1114 Sentence denotes However, the treatment of YS cells with RC-toxin caused a decrease of adenylate cyclase activity when the activity was measured at a substrate concentration of 0.15 mM ATP.
T9 1115-1242 Sentence denotes In contrast, there was little difference with the control when the activity was assayed at a higher ATP concentration, 0.24 mM.
T10 1243-1428 Sentence denotes It was found that the K-m of adenylate cyclase for ATP was changed by RC-toxin from 0.1 to 0.25 mM, and that the Mg2+ activation of the enzyme observable in untreated cells disappeared.
T11 1429-1611 Sentence denotes These results suggested that the decrease in the level of cyclic AMP in YS cells induced by RC-toxin can be explained in terms of the change in K-m of the adenylate cyclase activity.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 251-258 HP_0001541 denotes ascites
T2 259-266 HP_0100242 denotes sarcoma

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 547-554 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 95-102 Phenotype denotes ascites HP:0001541
T2 103-110 Phenotype denotes sarcoma HP:0100242
T3 251-258 Phenotype denotes ascites HP:0001541
T4 259-266 Phenotype denotes sarcoma HP:0100242

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 103-110 Disease denotes sarcoma http://purl.obolibrary.org/obo/MONDO_0005089
T2 259-266 Disease denotes sarcoma http://purl.obolibrary.org/obo/MONDO_0005089

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 547-554 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 95-102 Phenotype denotes ascites HP:0001541
T2 103-110 Phenotype denotes sarcoma HP:0100242
T3 251-258 Phenotype denotes ascites HP:0001541
T4 259-266 Phenotype denotes sarcoma HP:0100242

Organism-PubDic

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Species denotes Ricinus communis 3988
T2 302-318 Species denotes Ricinus communis 3988

Organism-PubDic-Bert-9

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Species denotes Ricinus communis 3988
T2 302-318 Species denotes Ricinus communis 3988
T3 326-334 Species denotes RC-toxin 3988
T4 464-472 Species denotes RC-toxin 3988
T5 560-568 Species denotes RC-toxin 3988
T6 595-603 Species denotes RC-toxin 3988
T7 698-706 Species denotes RC-toxin 3988
T8 982-990 Species denotes RC-toxin 3988
T9 1313-1321 Species denotes RC-toxin 3988
T10 1521-1529 Species denotes RC-toxin 3988

Organism-PubDic-Bert-8

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Species denotes Ricinus communis 3988
T2 87-94 Species denotes Yoshida 1364882
T3 140-143 Species denotes mug 1311525
T4 243-250 Species denotes Yoshida 1364882
T5 302-318 Species denotes Ricinus communis 3988
T6 326-334 Species denotes RC-toxin 3988
T7 464-472 Species denotes RC-toxin 3988
T8 478-481 Species denotes mug 1311525
T9 560-568 Species denotes RC-toxin 3988
T10 595-603 Species denotes RC-toxin 3988
T11 698-706 Species denotes RC-toxin 3988
T12 886-892 Species denotes change 1766596
T13 982-990 Species denotes RC-toxin 3988
T14 1138-1144 Species denotes little 35885
T15 1313-1321 Species denotes RC-toxin 3988
T16 1521-1529 Species denotes RC-toxin 3988
T17 1559-1569 Species denotes the change 1766596

Organism-Gold

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Species denotes Ricinus communis 3988
T2 302-318 Species denotes Ricinus communis 3988

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 10-26 Organism denotes Ricinus communis 3988
T2 302-318 Organism denotes Ricinus communis 3988

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 95-102 Body_part denotes ascites http://purl.obolibrary.org/obo/UBERON_0007795
T2 251-258 Body_part denotes ascites http://purl.obolibrary.org/obo/UBERON_0007795
T3 722-730 Body_part denotes membrane http://purl.obolibrary.org/obo/UBERON_0000094

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 103-110 Disease denotes sarcoma MONDO:0005089
T2 259-266 Disease denotes sarcoma MONDO:0005089

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 10-26 OrganismTaxon denotes Ricinus communis 3988
T2 302-318 OrganismTaxon denotes Ricinus communis 3988

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-117 Sentence denotes Effect of Ricinus communis toxin on cyclic adenosine 3':5'-monophosphate metabolism in Yoshida ascites sarcoma cells.
T2 118-296 Sentence denotes Prostaglandin E1 (2.5 mug/ml) enhanced the level of cyclic adenosine 3':5'-monophosphate (cyclic AMP) three to four times in Yoshida ascites sarcoma (YS) cells cultured in vitro.
T3 297-460 Sentence denotes When Ricinus communis toxin (RC-toxin) was added 30 min after the addition of prostaglandin E1, the enhanced level of cyclic AMP in the YS cells decreased rapidly.
T4 461-526 Sentence denotes Of RC-toxin, 0.2 mug/ml was enough to produce the maximum effect.
T5 527-653 Sentence denotes By addition of 5 mM lactose with RC-toxin, approximately 60% of the RC-toxin effect on the levels of cyclic AMP was abolished.
T6 654-804 Sentence denotes This indicates that the specific binding of RC-toxin on the surface membrane is largely responsible for the observed decrease of the cyclic AMP level.
T7 805-941 Sentence denotes The toxin treatment did not induce either leakage of cyclic AMP from the cell or change in the activity of cyclic AMP phosphodiesterase.
T8 942-1114 Sentence denotes However, the treatment of YS cells with RC-toxin caused a decrease of adenylate cyclase activity when the activity was measured at a substrate concentration of 0.15 mM ATP.
T9 1115-1242 Sentence denotes In contrast, there was little difference with the control when the activity was assayed at a higher ATP concentration, 0.24 mM.
T10 1243-1428 Sentence denotes It was found that the K-m of adenylate cyclase for ATP was changed by RC-toxin from 0.1 to 0.25 mM, and that the Mg2+ activation of the enzyme observable in untreated cells disappeared.
T11 1429-1611 Sentence denotes These results suggested that the decrease in the level of cyclic AMP in YS cells induced by RC-toxin can be explained in terms of the change in K-m of the adenylate cyclase activity.

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 95-102 Body_part denotes ascites http://purl.obolibrary.org/obo/UBERON_0007795
T2 251-258 Body_part denotes ascites http://purl.obolibrary.org/obo/UBERON_0007795
T3 722-730 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158