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PubMed:16373355 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1293-1304 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT

sentences

Id Subject Object Predicate Lexical cue
T1 0-104 Sentence denotes Proteoglycan mechanics studied by single-molecule force spectroscopy of allotypic cell adhesion glycans.
T2 105-260 Sentence denotes Early Metazoans had to evolve the first cell adhesion system addressed to maintaining stable interactions between cells constituting different individuals.
T3 261-407 Sentence denotes As the oldest extant multicellular animals, sponges are good candidates to have remnants of the molecules responsible for that crucial innovation.
T4 408-613 Sentence denotes Sponge cells associate in a species-specific process through multivalent calcium-dependent interactions of carbohydrate structures on an extracellular membrane-bound proteoglycan termed aggregation factor.
T5 614-780 Sentence denotes Single-molecule force spectroscopy studies of the mechanics of aggregation factor self-binding indicate the existence of intermolecular carbohydrate adhesion domains.
T6 781-963 Sentence denotes A 200-kDa aggregation factor glycan (g200) involved in cell adhesion exhibits interindividual differences in size and epitope content which suggest the existence of allelic variants.
T7 964-1062 Sentence denotes We have purified two of these g200 distinct forms from two individuals of the same sponge species.
T8 1063-1155 Sentence denotes Comparison of allotypic versus isotypic g200 binding forces reveals significant differences.
T9 1156-1313 Sentence denotes Surface plasmon resonance measurements show that g200 self-adhesion is much stronger than its binding to other unrelated glycans such as chondroitin sulfate.
T10 1314-1505 Sentence denotes This adhesive specificity through multiple carbohydrate binding domains is a type of cooperative interaction that can contribute to explain some functions of modular proteoglycans in general.
T11 1506-1787 Sentence denotes From our results it can be deduced that the binding strength/surface area between two aggregation factor molecules is comparable with that of focal contacts in vertebrate cells, indicating that strong carbohydrate-based cell adhesions evolved at the very start of Metazoan history.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1666-1676 http://purl.obolibrary.org/obo/MAT_0000373 denotes vertebrate

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1293-1304 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 1293-1304 GlycoEpitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1666-1676 Body_part denotes vertebrate http://purl.obolibrary.org/obo/MAT_0000373

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1293-1304 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1293-1304 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 282-303 OrganismTaxon denotes multicellular animals 33208

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 545-558 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T2 559-567 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1666-1676 Body_part denotes vertebrate http://purl.obolibrary.org/obo/MAT_0000373

sentences

Id Subject Object Predicate Lexical cue
T1 0-104 Sentence denotes Proteoglycan mechanics studied by single-molecule force spectroscopy of allotypic cell adhesion glycans.
T2 105-260 Sentence denotes Early Metazoans had to evolve the first cell adhesion system addressed to maintaining stable interactions between cells constituting different individuals.
T3 261-407 Sentence denotes As the oldest extant multicellular animals, sponges are good candidates to have remnants of the molecules responsible for that crucial innovation.
T4 408-613 Sentence denotes Sponge cells associate in a species-specific process through multivalent calcium-dependent interactions of carbohydrate structures on an extracellular membrane-bound proteoglycan termed aggregation factor.
T5 614-780 Sentence denotes Single-molecule force spectroscopy studies of the mechanics of aggregation factor self-binding indicate the existence of intermolecular carbohydrate adhesion domains.
T6 781-963 Sentence denotes A 200-kDa aggregation factor glycan (g200) involved in cell adhesion exhibits interindividual differences in size and epitope content which suggest the existence of allelic variants.
T7 964-1062 Sentence denotes We have purified two of these g200 distinct forms from two individuals of the same sponge species.
T8 1063-1155 Sentence denotes Comparison of allotypic versus isotypic g200 binding forces reveals significant differences.
T9 1156-1313 Sentence denotes Surface plasmon resonance measurements show that g200 self-adhesion is much stronger than its binding to other unrelated glycans such as chondroitin sulfate.
T10 1314-1505 Sentence denotes This adhesive specificity through multiple carbohydrate binding domains is a type of cooperative interaction that can contribute to explain some functions of modular proteoglycans in general.
T11 1506-1787 Sentence denotes From our results it can be deduced that the binding strength/surface area between two aggregation factor molecules is comparable with that of focal contacts in vertebrate cells, indicating that strong carbohydrate-based cell adhesions evolved at the very start of Metazoan history.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-104 Sentence denotes Proteoglycan mechanics studied by single-molecule force spectroscopy of allotypic cell adhesion glycans.
T2 105-260 Sentence denotes Early Metazoans had to evolve the first cell adhesion system addressed to maintaining stable interactions between cells constituting different individuals.
T3 261-407 Sentence denotes As the oldest extant multicellular animals, sponges are good candidates to have remnants of the molecules responsible for that crucial innovation.
T4 408-613 Sentence denotes Sponge cells associate in a species-specific process through multivalent calcium-dependent interactions of carbohydrate structures on an extracellular membrane-bound proteoglycan termed aggregation factor.
T5 614-780 Sentence denotes Single-molecule force spectroscopy studies of the mechanics of aggregation factor self-binding indicate the existence of intermolecular carbohydrate adhesion domains.
T6 781-963 Sentence denotes A 200-kDa aggregation factor glycan (g200) involved in cell adhesion exhibits interindividual differences in size and epitope content which suggest the existence of allelic variants.
T7 964-1062 Sentence denotes We have purified two of these g200 distinct forms from two individuals of the same sponge species.
T8 1063-1155 Sentence denotes Comparison of allotypic versus isotypic g200 binding forces reveals significant differences.
T9 1156-1313 Sentence denotes Surface plasmon resonance measurements show that g200 self-adhesion is much stronger than its binding to other unrelated glycans such as chondroitin sulfate.
T10 1314-1505 Sentence denotes This adhesive specificity through multiple carbohydrate binding domains is a type of cooperative interaction that can contribute to explain some functions of modular proteoglycans in general.
T11 1506-1787 Sentence denotes From our results it can be deduced that the binding strength/surface area between two aggregation factor molecules is comparable with that of focal contacts in vertebrate cells, indicating that strong carbohydrate-based cell adhesions evolved at the very start of Metazoan history.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1293-1304 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1293-1304 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 282-303 OrganismTaxon denotes multicellular animals 33208

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 545-558 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T2 559-567 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158