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PubMed:16373330 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 465-471 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 465-471 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 465-471 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 239-246 HP_0012393 denotes allergy
T2 1487-1494 HP_0012393 denotes allergy

ICD10

Id Subject Object Predicate Lexical cue
T1 239-246 http://purl.bioontology.org/ontology/ICD10/T78.4 denotes allergy
T2 1487-1494 http://purl.bioontology.org/ontology/ICD10/T78.4 denotes allergy

uniprot-human

Id Subject Object Predicate Lexical cue
T1 1234-1246 http://www.uniprot.org/uniprot/P02787 denotes transferrins

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 1196-1201 http://www.uniprot.org/uniprot/Q9WUD1 denotes chips
T2 1234-1246 http://www.uniprot.org/uniprot/Q63915 denotes transferrins

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 333-343 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal

GO-BP

Id Subject Object Predicate Lexical cue
T1 150-161 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T2 750-761 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T3 944-955 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T4 150-171 http://purl.obolibrary.org/obo/GO_0036071 denotes fucosylated N-glycans
T5 906-910 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T6 1004-1008 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T7 1102-1106 http://purl.obolibrary.org/obo/GO_0004617 denotes sera

GO-MF

Id Subject Object Predicate Lexical cue
T1 0-14 http://purl.obolibrary.org/obo/GO_0003823 denotes Immunoglobulin
T2 30-37 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 362-369 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T4 1421-1428 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T5 30-37 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T6 362-369 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T7 1421-1428 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T8 30-37 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T9 362-369 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T10 1421-1428 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T11 30-37 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12 362-369 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T13 1421-1428 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T14 344-354 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T15 522-532 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T16 685-695 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T17 1338-1348 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T18 1473-1483 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies

GO-CC

Id Subject Object Predicate Lexical cue
T1 136-140 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T2 451-455 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T3 832-836 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T4 625-629 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 1334-1348 http://purl.obolibrary.org/obo/GO_0071736 denotes IgG antibodies
T6 1469-1483 http://purl.obolibrary.org/obo/GO_0071743 denotes IgE antibodies

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 38-43 http://edamontology.org/topic_0780 denotes plant
T2 177-183 http://edamontology.org/topic_0780 denotes plants
T3 188-199 http://edamontology.org/topic_2830 denotes immunogenic
T4 239-246 http://edamontology.org/topic_3400 denotes allergy
T5 267-272 http://edamontology.org/topic_0780 denotes plant
T6 278-285 http://edamontology.org/topic_0078 denotes protein
T7 370-375 http://edamontology.org/topic_0780 denotes plant
T8 585-590 http://edamontology.org/topic_0780 denotes plant
T9 1196-1201 http://edamontology.org/topic_3179 denotes chips
T10 1356-1368 http://edamontology.org/topic_0152 denotes carbohydrate
T11 1487-1494 http://edamontology.org/topic_3400 denotes allergy

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 82-91 http://edamontology.org/operation_3429 denotes generated
T2 278-285 http://edamontology.org/data_1467 denotes protein
T3 278-285 http://edamontology.org/format_1208 denotes protein
T4 324-332 http://edamontology.org/operation_3429 denotes generate
T5 472-479 http://edamontology.org/data_1756 denotes residue
T6 641-649 http://edamontology.org/operation_3429 denotes generate
T7 1075-1081 http://edamontology.org/data_2082 denotes matrix
T8 1170-1182 http://edamontology.org/data_3108 denotes measurements

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-119 Sentence denotes Immunoglobulin G specifically binding plant N-glycans with high affinity could be generated in rabbits but not in mice.
TextSentencer_T2 120-302 Sentence denotes Xylosylated and core alpha1,3-fucosylated N-glycans from plants are immunogenic, and they play a still obscure role in allergy and in the field of plant-made protein pharmaceuticals.
TextSentencer_T3 303-480 Sentence denotes We immunized mice to generate monoclonal antibodies (mAbs) binding plant N-glycans specifically via the epitope containing either the xylose or the core alpha1,3-fucose residue.
TextSentencer_T4 481-696 Sentence denotes Splenocytes expressing N-glycan-specific antibodies derived from C57BL/6 mice previously immunized with plant glycoproteins were preselected by cell sorting to generate hybridoma lines producing specific antibodies.
TextSentencer_T5 697-849 Sentence denotes However, we obtained only mAbs unable to distinguish fucosylated from xylosylated N-glycans and reactive even with the pentasaccharide core Man3GlcNAc2.
TextSentencer_T6 850-981 Sentence denotes In contrast, immunization of rabbits yielded polyclonal sera selectively reactive with either fucosylated or xylosylated N-glycans.
TextSentencer_T7 982-1143 Sentence denotes Purification of these sera using glyco-modified neoglycoproteins coupled to a chromatography matrix provided polyclonal sera suitable for affinity determination.
TextSentencer_T8 1144-1298 Sentence denotes Surface plasmon resonance measurements using sensor chips with immobilized glyco-modified transferrins revealed dissociation constants of around 10(-9) M.
TextSentencer_T9 1299-1495 Sentence denotes This unexpectedly high affinity of IgG antibodies toward carbohydrate epitopes has repercussions on our conception of the binding strength and significance of antiglycan IgE antibodies in allergy.
T1 0-119 Sentence denotes Immunoglobulin G specifically binding plant N-glycans with high affinity could be generated in rabbits but not in mice.
T2 120-302 Sentence denotes Xylosylated and core alpha1,3-fucosylated N-glycans from plants are immunogenic, and they play a still obscure role in allergy and in the field of plant-made protein pharmaceuticals.
T3 303-480 Sentence denotes We immunized mice to generate monoclonal antibodies (mAbs) binding plant N-glycans specifically via the epitope containing either the xylose or the core alpha1,3-fucose residue.
T4 481-696 Sentence denotes Splenocytes expressing N-glycan-specific antibodies derived from C57BL/6 mice previously immunized with plant glycoproteins were preselected by cell sorting to generate hybridoma lines producing specific antibodies.
T5 697-849 Sentence denotes However, we obtained only mAbs unable to distinguish fucosylated from xylosylated N-glycans and reactive even with the pentasaccharide core Man3GlcNAc2.
T6 850-981 Sentence denotes In contrast, immunization of rabbits yielded polyclonal sera selectively reactive with either fucosylated or xylosylated N-glycans.
T7 982-1143 Sentence denotes Purification of these sera using glyco-modified neoglycoproteins coupled to a chromatography matrix provided polyclonal sera suitable for affinity determination.
T8 1144-1495 Sentence denotes Surface plasmon resonance measurements using sensor chips with immobilized glyco-modified transferrins revealed dissociation constants of around 10(-9) M. This unexpectedly high affinity of IgG antibodies toward carbohydrate epitopes has repercussions on our conception of the binding strength and significance of antiglycan IgE antibodies in allergy.
T1 0-119 Sentence denotes Immunoglobulin G specifically binding plant N-glycans with high affinity could be generated in rabbits but not in mice.
T2 120-302 Sentence denotes Xylosylated and core alpha1,3-fucosylated N-glycans from plants are immunogenic, and they play a still obscure role in allergy and in the field of plant-made protein pharmaceuticals.
T3 303-480 Sentence denotes We immunized mice to generate monoclonal antibodies (mAbs) binding plant N-glycans specifically via the epitope containing either the xylose or the core alpha1,3-fucose residue.
T4 481-696 Sentence denotes Splenocytes expressing N-glycan-specific antibodies derived from C57BL/6 mice previously immunized with plant glycoproteins were preselected by cell sorting to generate hybridoma lines producing specific antibodies.
T5 697-849 Sentence denotes However, we obtained only mAbs unable to distinguish fucosylated from xylosylated N-glycans and reactive even with the pentasaccharide core Man3GlcNAc2.
T6 850-981 Sentence denotes In contrast, immunization of rabbits yielded polyclonal sera selectively reactive with either fucosylated or xylosylated N-glycans.
T7 982-1143 Sentence denotes Purification of these sera using glyco-modified neoglycoproteins coupled to a chromatography matrix provided polyclonal sera suitable for affinity determination.
T8 1144-1298 Sentence denotes Surface plasmon resonance measurements using sensor chips with immobilized glyco-modified transferrins revealed dissociation constants of around 10(-9) M.
T9 1299-1495 Sentence denotes This unexpectedly high affinity of IgG antibodies toward carbohydrate epitopes has repercussions on our conception of the binding strength and significance of antiglycan IgE antibodies in allergy.

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 44-53 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T2 162-171 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T3 376-385 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T4 779-788 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T5 504-512 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycan

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 239-246 Disease denotes allergy http://purl.obolibrary.org/obo/MONDO_0005271
T2 1487-1494 Disease denotes allergy http://purl.obolibrary.org/obo/MONDO_0005271

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 239-246 Phenotype denotes allergy HP:0012393
T2 1487-1494 Phenotype denotes allergy HP:0012393

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 95-102 OrganismTaxon denotes rabbits 9986
T2 114-118 OrganismTaxon denotes mice 10088
T3 316-320 OrganismTaxon denotes mice 10088
T4 554-558 OrganismTaxon denotes mice 10088
T5 879-886 OrganismTaxon denotes rabbits 9986

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 481-492 Body_part denotes Splenocytes http://purl.obolibrary.org/obo/CL_2000074

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 481-492 Cell denotes Splenocytes http://purl.obolibrary.org/obo/CL:2000074