PubMed:16371368 / 0-199 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/16371368","sourcedb":"PubMed","sourceid":"16371368","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/16371368","text":"Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling.\nMutations in SHP-2 phosphatase that cause hyperactivation of its catalytic activity have be","tracks":[{"project":"sonoma2","denotations":[{"id":"T-0","span":{"begin":108,"end":117},"obj":"VAR"},{"id":"T-1","span":{"begin":121,"end":126},"obj":"GENE"},{"id":"T-2","span":{"begin":144,"end":149},"obj":"REG"},{"id":"T-3","span":{"begin":150,"end":165},"obj":"POSREG"},{"id":"T-4","span":{"begin":173,"end":191},"obj":"MPA"}],"relations":[{"id":"R-0","pred":"CauseOf","subj":"T-0","obj":"T-2"},{"id":"R-1","pred":"CauseOf","subj":"T-0","obj":"T-3"},{"id":"R-3","pred":"ThemeOf","subj":"T-1","obj":"T-0"},{"id":"R-4","pred":"ThemeOf","subj":"T-4","obj":"T-3"}],"attributes":[{"subj":"T-0","pred":"source","obj":"sonoma2"},{"subj":"T-1","pred":"source","obj":"sonoma2"},{"subj":"T-2","pred":"source","obj":"sonoma2"},{"subj":"T-3","pred":"source","obj":"sonoma2"},{"subj":"T-4","pred":"source","obj":"sonoma2"}]},{"project":"sonoma","denotations":[{"id":"T-0","span":{"begin":0,"end":7},"obj":"REG"},{"id":"T-1","span":{"begin":33,"end":49},"obj":"POSREG"},{"id":"T-2","span":{"begin":50,"end":58},"obj":"VAR"},{"id":"T-3","span":{"begin":62,"end":79},"obj":"GENE"},{"id":"T-4","span":{"begin":108,"end":117},"obj":"VAR"},{"id":"T-5","span":{"begin":121,"end":138},"obj":"GENE"},{"id":"T-6","span":{"begin":144,"end":149},"obj":"REG"},{"id":"T-7","span":{"begin":150,"end":165},"obj":"POSREG"},{"id":"T-8","span":{"begin":173,"end":191},"obj":"MPA"}],"relations":[{"id":"R-0","pred":"CauseOf","subj":"T-0","obj":"T-2"},{"id":"R-1","pred":"ThemeOf","subj":"T-0","obj":"T-3"},{"id":"R-2","pred":"CauseOf","subj":"T-1","obj":"T-2"},{"id":"R-3","pred":"ThemeOf","subj":"T-1","obj":"T-3"},{"id":"R-4","pred":"ThemeOf","subj":"T-2","obj":"T-3"},{"id":"R-5","pred":"ThemeOf","subj":"T-4","obj":"T-5"},{"id":"R-6","pred":"CauseOf","subj":"T-4","obj":"T-6"},{"id":"R-7","pred":"CauseOf","subj":"T-4","obj":"T-7"},{"id":"R-13","pred":"ThemeOf","subj":"T-6","obj":"T-8"},{"id":"R-16","pred":"ThemeOf","subj":"T-7","obj":"T-8"}],"attributes":[{"subj":"T-0","pred":"source","obj":"sonoma"},{"subj":"T-1","pred":"source","obj":"sonoma"},{"subj":"T-2","pred":"source","obj":"sonoma"},{"subj":"T-3","pred":"source","obj":"sonoma"},{"subj":"T-4","pred":"source","obj":"sonoma"},{"subj":"T-5","pred":"source","obj":"sonoma"},{"subj":"T-6","pred":"source","obj":"sonoma"},{"subj":"T-7","pred":"source","obj":"sonoma"},{"subj":"T-8","pred":"source","obj":"sonoma"}]},{"project":"sentences","denotations":[{"id":"T1","span":{"begin":0,"end":107},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T1","pred":"source","obj":"sentences"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":150,"end":165},"obj":"HP_0000752"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"16371368-0#62#67#gene5781","span":{"begin":62,"end":67},"obj":"gene5781"},{"id":"16371368-0#13#21#diseaseC0023418","span":{"begin":13,"end":21},"obj":"diseaseC0023418"}],"relations":[{"id":"62#67#gene578113#21#diseaseC0023418","pred":"associated_with","subj":"16371368-0#62#67#gene5781","obj":"16371368-0#13#21#diseaseC0023418"}],"attributes":[{"subj":"16371368-0#62#67#gene5781","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16371368-0#13#21#diseaseC0023418","pred":"source","obj":"DisGeNET5_gene_disease"}]},{"project":"kaiyin_test","denotations":[{"id":"T1","span":{"begin":108,"end":117},"obj":"Var"},{"id":"T2","span":{"begin":121,"end":126},"obj":"Gene"},{"id":"T3","span":{"begin":127,"end":138},"obj":"Enzyme"},{"id":"T4","span":{"begin":150,"end":165},"obj":"PosReg"},{"id":"T5","span":{"begin":173,"end":191},"obj":"MPA"}],"relations":[{"id":"R1","pred":"ThemeOf","subj":"T3","obj":"T2"},{"id":"R2","pred":"ThemeOf","subj":"T2","obj":"T1"},{"id":"R3","pred":"CauseOf","subj":"T1","obj":"T4"},{"id":"R4","pred":"ThemeOf","subj":"T5","obj":"T4"}],"attributes":[{"subj":"T1","pred":"source","obj":"kaiyin_test"},{"subj":"T2","pred":"source","obj":"kaiyin_test"},{"subj":"T3","pred":"source","obj":"kaiyin_test"},{"subj":"T4","pred":"source","obj":"kaiyin_test"},{"subj":"T5","pred":"source","obj":"kaiyin_test"}]},{"project":"name_no","denotations":[{"id":"T1","span":{"begin":108,"end":117},"obj":"Var"},{"id":"T2","span":{"begin":121,"end":126},"obj":"Gene"},{"id":"T3","span":{"begin":127,"end":138},"obj":"Enzyme"},{"id":"T4","span":{"begin":150,"end":165},"obj":"PosReg"},{"id":"T5","span":{"begin":173,"end":191},"obj":"MPA"}],"relations":[{"id":"R1","pred":"ThemeOf","subj":"T3","obj":"T2"},{"id":"R2","pred":"ThemeOf","subj":"T2","obj":"T1"},{"id":"R3","pred":"CauseOf","subj":"T1","obj":"T4"},{"id":"R4","pred":"ThemeOf","subj":"T5","obj":"T4"}],"attributes":[{"subj":"T1","pred":"source","obj":"name_no"},{"subj":"T2","pred":"source","obj":"name_no"},{"subj":"T3","pred":"source","obj":"name_no"},{"subj":"T4","pred":"source","obj":"name_no"},{"subj":"T5","pred":"source","obj":"name_no"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":62,"end":67},"obj":"gene:5781"},{"id":"T1","span":{"begin":13,"end":21},"obj":"disease:C0023418"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"}]},{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":13,"end":21},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005059"},{"subj":"T1","pred":"source","obj":"mondo_disease"}]},{"project":"HP-phenotype","denotations":[{"id":"T1","span":{"begin":13,"end":21},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"HP:0001909"},{"subj":"T1","pred":"source","obj":"HP-phenotype"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sonoma2","color":"#ec93bd","default":true},{"id":"sonoma","color":"#93d7ec"},{"id":"sentences","color":"#ece793"},{"id":"PubmedHPO","color":"#cd93ec"},{"id":"DisGeNET5_gene_disease","color":"#93ecb3"},{"id":"kaiyin_test","color":"#ec9993"},{"id":"name_no","color":"#93a7ec"},{"id":"DisGeNET","color":"#c1ec93"},{"id":"mondo_disease","color":"#ec93db"},{"id":"HP-phenotype","color":"#93ece3"}]}]}}