PubMed:16361247 / 1086-1550 JSONTXT

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    sentences

    {"project":"sentences","denotations":[{"id":"TextSentencer_T5","span":{"begin":0,"end":464},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":464},"obj":"Sentence"},{"id":"T5","span":{"begin":0,"end":464},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    GlycoBiology-GDGDB

    {"project":"GlycoBiology-GDGDB","denotations":[{"id":"_T19","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00012"},{"id":"_T20","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00013"},{"id":"_T21","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00014"},{"id":"_T22","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00015"},{"id":"_T23","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00016"},{"id":"_T24","span":{"begin":286,"end":290},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00017"},{"id":"_T25","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00012"},{"id":"_T26","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00013"},{"id":"_T27","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00014"},{"id":"_T28","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00015"},{"id":"_T29","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00016"},{"id":"_T30","span":{"begin":338,"end":342},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00017"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    uniprot-human

    {"project":"uniprot-human","denotations":[{"id":"T5","span":{"begin":286,"end":290},"obj":"http://www.uniprot.org/uniprot/Q99519"},{"id":"T6","span":{"begin":338,"end":342},"obj":"http://www.uniprot.org/uniprot/Q99519"},{"id":"T10","span":{"begin":386,"end":390},"obj":"http://www.uniprot.org/uniprot/P10619"},{"id":"T13","span":{"begin":352,"end":354},"obj":"http://www.uniprot.org/uniprot/P69208"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    uniprot-mouse

    {"project":"uniprot-mouse","denotations":[{"id":"T4","span":{"begin":386,"end":390},"obj":"http://www.uniprot.org/uniprot/P16675"},{"id":"T7","span":{"begin":343,"end":348},"obj":"http://www.uniprot.org/uniprot/O35625"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    GlycoBiology-NCBITAXON

    {"project":"GlycoBiology-NCBITAXON","denotations":[{"id":"T5","span":{"begin":235,"end":243},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/871272"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T5","span":{"begin":13,"end":36},"obj":"http://purl.obolibrary.org/obo/GO_0006487"},{"id":"T7","span":{"begin":15,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0070085"},{"id":"T9","span":{"begin":15,"end":36},"obj":"http://purl.obolibrary.org/obo/GO_0006486"},{"id":"T11","span":{"begin":162,"end":171},"obj":"http://purl.obolibrary.org/obo/GO_0000746"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T4","span":{"begin":93,"end":102},"obj":"http://purl.obolibrary.org/obo/GO_0005764"},{"id":"T5","span":{"begin":272,"end":285},"obj":"http://purl.obolibrary.org/obo/GO_0005622"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    EDAM-topics

    {"project":"EDAM-topics","denotations":[{"id":"T8","span":{"begin":28,"end":36},"obj":"http://edamontology.org/topic_0078"},{"id":"T9","span":{"begin":28,"end":45},"obj":"http://edamontology.org/topic_3074"},{"id":"T10","span":{"begin":93,"end":102},"obj":"http://edamontology.org/topic_0616"},{"id":"T11","span":{"begin":359,"end":367},"obj":"http://edamontology.org/topic_0080"},{"id":"T12","span":{"begin":359,"end":367},"obj":"http://edamontology.org/topic_3168"},{"id":"T13","span":{"begin":391,"end":395},"obj":"http://edamontology.org/topic_3512"},{"id":"T14","span":{"begin":456,"end":463},"obj":"http://edamontology.org/topic_0078"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    EDAM-DFO

    {"project":"EDAM-DFO","denotations":[{"id":"T10","span":{"begin":28,"end":36},"obj":"http://edamontology.org/data_1467"},{"id":"T11","span":{"begin":28,"end":36},"obj":"http://edamontology.org/format_1208"},{"id":"T12","span":{"begin":28,"end":45},"obj":"http://edamontology.org/operation_3087"},{"id":"T13","span":{"begin":28,"end":45},"obj":"http://edamontology.org/operation_3092"},{"id":"T14","span":{"begin":37,"end":45},"obj":"http://edamontology.org/operation_2423"},{"id":"T15","span":{"begin":359,"end":367},"obj":"http://edamontology.org/data_2044"},{"id":"T16","span":{"begin":359,"end":367},"obj":"http://edamontology.org/operation_3218"},{"id":"T17","span":{"begin":456,"end":463},"obj":"http://edamontology.org/data_1467"},{"id":"T18","span":{"begin":456,"end":463},"obj":"http://edamontology.org/format_1208"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    DisGeNET5_gene_disease

    {"project":"DisGeNET5_gene_disease","denotations":[{"id":"16361247-4#286#290#gene4758","span":{"begin":286,"end":290},"obj":"gene4758"},{"id":"16361247-4#338#342#gene4758","span":{"begin":338,"end":342},"obj":"gene4758"},{"id":"16361247-4#286#290#gene4758","span":{"begin":286,"end":290},"obj":"gene4758"},{"id":"16361247-4#338#342#gene4758","span":{"begin":338,"end":342},"obj":"gene4758"},{"id":"16361247-4#175#185#diseaseC0026697","span":{"begin":175,"end":185},"obj":"diseaseC0026697"},{"id":"16361247-4#175#185#diseaseC0268226","span":{"begin":175,"end":185},"obj":"diseaseC0268226"},{"id":"16361247-4#175#185#diseaseC0026697","span":{"begin":175,"end":185},"obj":"diseaseC0026697"},{"id":"16361247-4#175#185#diseaseC0268226","span":{"begin":175,"end":185},"obj":"diseaseC0268226"},{"id":"16361247-4#190#207#diseaseC0268233","span":{"begin":190,"end":207},"obj":"diseaseC0268233"}],"relations":[{"id":"286#290#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"286#290#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"286#290#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"286#290#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"286#290#gene4758190#207#diseaseC0268233","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#190#207#diseaseC0268233"},{"id":"338#342#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"338#342#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"338#342#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"338#342#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"338#342#gene4758190#207#diseaseC0268233","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#190#207#diseaseC0268233"},{"id":"286#290#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"286#290#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"286#290#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"286#290#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"286#290#gene4758190#207#diseaseC0268233","pred":"associated_with","subj":"16361247-4#286#290#gene4758","obj":"16361247-4#190#207#diseaseC0268233"},{"id":"338#342#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"338#342#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"338#342#gene4758175#185#diseaseC0026697","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0026697"},{"id":"338#342#gene4758175#185#diseaseC0268226","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#175#185#diseaseC0268226"},{"id":"338#342#gene4758190#207#diseaseC0268233","pred":"associated_with","subj":"16361247-4#338#342#gene4758","obj":"16361247-4#190#207#diseaseC0268233"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    Lectin

    {"project":"Lectin","denotations":[{"id":"Lectin_T2","span":{"begin":49,"end":52},"obj":"https://acgg.asia/db/lfdb/LfDB0228"},{"id":"Lectin_T3","span":{"begin":151,"end":154},"obj":"https://acgg.asia/db/lfdb/LfDB0228"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    DisGeNET

    {"project":"DisGeNET","denotations":[{"id":"T38","span":{"begin":286,"end":290},"obj":"gene:4758"},{"id":"T39","span":{"begin":175,"end":185},"obj":"disease:C0268226"},{"id":"T40","span":{"begin":286,"end":290},"obj":"gene:51162"},{"id":"T41","span":{"begin":175,"end":185},"obj":"disease:C0268226"},{"id":"T42","span":{"begin":286,"end":290},"obj":"gene:4758"},{"id":"T43","span":{"begin":190,"end":207},"obj":"disease:C0268233"},{"id":"T44","span":{"begin":286,"end":290},"obj":"gene:51162"},{"id":"T45","span":{"begin":190,"end":207},"obj":"disease:C0268233"},{"id":"T46","span":{"begin":338,"end":342},"obj":"gene:4758"},{"id":"T47","span":{"begin":190,"end":207},"obj":"disease:C0268233"},{"id":"T48","span":{"begin":338,"end":342},"obj":"gene:51162"},{"id":"T49","span":{"begin":190,"end":207},"obj":"disease:C0268233"}],"relations":[{"id":"R20","pred":"associated_with","subj":"T38","obj":"T39"},{"id":"R21","pred":"associated_with","subj":"T40","obj":"T41"},{"id":"R22","pred":"associated_with","subj":"T42","obj":"T43"},{"id":"R23","pred":"associated_with","subj":"T44","obj":"T45"},{"id":"R24","pred":"associated_with","subj":"T46","obj":"T47"},{"id":"R25","pred":"associated_with","subj":"T48","obj":"T49"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    mondo_disease

    {"project":"mondo_disease","denotations":[{"id":"T11","span":{"begin":175,"end":185},"obj":"Disease"},{"id":"T12","span":{"begin":190,"end":207},"obj":"Disease"}],"attributes":[{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0017734"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0009737"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    Lectin-Jamboree

    {"project":"Lectin-Jamboree","denotations":[{"id":"T2","span":{"begin":53,"end":59},"obj":"lectin"},{"id":"T3","span":{"begin":155,"end":161},"obj":"lectin"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    Lectin-Jamboree-small

    {"project":"Lectin-Jamboree-small","denotations":[{"id":"T2","span":{"begin":49,"end":52},"obj":"Lectin"},{"id":"T3","span":{"begin":151,"end":154},"obj":"Lectin"}],"attributes":[{"id":"A2","pred":"glycosmos_id","subj":"T2","obj":"GL_001868"},{"id":"A3","pred":"glycosmos_id","subj":"T3","obj":"GL_001868"}],"namespaces":[{"prefix":"_base","uri":"https://glycosmos.org/lectins/"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    Lectin-Jamboree-Sentence

    {"project":"Lectin-Jamboree-Sentence","blocks":[{"id":"T4","span":{"begin":0,"end":464},"obj":"Sentence"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    NCBITAXON

    {"project":"NCBITAXON","denotations":[{"id":"T3","span":{"begin":49,"end":52},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":151,"end":154},"obj":"OrganismTaxon"}],"attributes":[{"id":"A3","pred":"db_id","subj":"T3","obj":"37501"},{"id":"A4","pred":"db_id","subj":"T4","obj":"37501"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    Anatomy-UBERON

    {"project":"Anatomy-UBERON","denotations":[{"id":"T4","span":{"begin":208,"end":219},"obj":"Body_part"},{"id":"T5","span":{"begin":272,"end":285},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/GO_0005622"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}

    CL-cell

    {"project":"CL-cell","denotations":[{"id":"T4","span":{"begin":208,"end":219},"obj":"Cell"}],"attributes":[{"id":"A4","pred":"cl_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL:0000057"}],"text":"The specific N-glycosylated proteins detected on MAM lectin blotting as well as the granular lysosomal fluorescence due to an avidin-FITC/biotinylated MAM lectin conjugate in sialidosis and galactosialidosis fibroblasts disappeared in parallel with the restoration of the intracellular NEU1 activity after transfection of the recombinant NEU1 fused to HA tag sequence and the wild-type PPCA cDNA as well as administration of the recombinant PPCA precursor protein."}