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PubMed:16292950 JSONTXT

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c_corpus

Id Subject Object Predicate Lexical cue
T1 101-110 D009369 denotes neoplasia
T2 101-110 D009369 denotes neoplasia
T3 126-136 SO:0000783 denotes engineered
T4 137-142 10090 denotes mouse
T5 137-142 D051379 denotes mouse
T6 153-159 UBERON:0000310 denotes breast
T7 153-166 D001943 denotes breast cancer
T8 153-166 D001943 denotes breast cancer
T9 190-196 UBERON:0000310 denotes breast
T10 190-203 D001943 denotes breast cancer
T11 190-203 D001943 denotes breast cancer
T12 338-344 UBERON:0000479 denotes tissue
T13 420-429 GO:0023052 denotes signaling
T14 510-514 C052968 denotes TiBa
T15 510-514 C052968 denotes TiBa
T16 510-514 CHEBI:73175 denotes TiBa
T17 596-607 UBERON:0002049 denotes vasculature
T18 626-635 SO:0000817 denotes wild-type
T19 652-662 SO:0000783 denotes engineered
T20 663-667 PR:000005054 denotes mice
T22 663-667 O89094 denotes mice
T21 663-667 D051379 denotes mice
T23 663-667 10095 denotes mice
T24 681-689 Q9PVZ9 denotes ER alpha
T25 681-689 Q9YHT3 denotes ER alpha
T26 681-689 P57717 denotes ER alpha
T27 681-689 Q9QZJ5 denotes ER alpha
T28 681-689 Q29040 denotes ER alpha
T29 681-689 P49886 denotes ER alpha
T30 681-689 P50240 denotes ER alpha
T31 681-689 Q91424 denotes ER alpha
T32 681-689 Q9YHZ7 denotes ER alpha
T33 681-689 P06211 denotes ER alpha
T34 681-689 P16058 denotes ER alpha
T35 681-689 P50242 denotes ER alpha
T36 681-689 Q53AD2 denotes ER alpha
T37 681-689 P49885 denotes ER alpha
T38 681-689 P49884 denotes ER alpha
T39 681-689 P19785 denotes ER alpha
T40 681-689 Q91250 denotes ER alpha
T41 681-689 P81559 denotes ER alpha
T42 681-689 Q9TV98 denotes ER alpha
T43 681-689 PR:000007204 denotes ER alpha
T44 681-689 Q9YH33 denotes ER alpha
T45 681-689 P50241 denotes ER alpha
T46 681-689 P06212 denotes ER alpha
T47 681-689 P03372 denotes ER alpha
T48 681-689 O42132 denotes ER alpha
T49 681-689 P57753 denotes ER alpha
T50 684-689 CHEBI:30216 denotes alpha
T53 700-724 D002285 denotes ductal carcinoma in situ
T54 700-724 D002285 denotes ductal carcinoma in situ
T60 726-730 CVCL_5552 denotes DCIS
T59 726-730 D002285 denotes DCIS
T61 726-730 D002285 denotes DCIS
T62 736-744 Q9PVZ9 denotes ER alpha
T63 736-744 Q9YHT3 denotes ER alpha
T64 736-744 P57717 denotes ER alpha
T65 736-744 Q9QZJ5 denotes ER alpha
T66 736-744 Q29040 denotes ER alpha
T67 736-744 P49886 denotes ER alpha
T68 736-744 P50240 denotes ER alpha
T69 736-744 Q91424 denotes ER alpha
T70 736-744 Q9YHZ7 denotes ER alpha
T71 736-744 P06211 denotes ER alpha
T72 736-744 P16058 denotes ER alpha
T73 736-744 P50242 denotes ER alpha
T74 736-744 Q53AD2 denotes ER alpha
T75 736-744 P49885 denotes ER alpha
T76 736-744 P49884 denotes ER alpha
T77 736-744 P19785 denotes ER alpha
T78 736-744 Q91250 denotes ER alpha
T79 736-744 P81559 denotes ER alpha
T80 736-744 Q9TV98 denotes ER alpha
T81 736-744 PR:000007204 denotes ER alpha
T82 736-744 Q9YH33 denotes ER alpha
T83 736-744 P50241 denotes ER alpha
T84 736-744 P06212 denotes ER alpha
T85 736-744 P03372 denotes ER alpha
T86 736-744 O42132 denotes ER alpha
T87 736-744 P57753 denotes ER alpha
T88 739-744 CHEBI:30216 denotes alpha
T89 761-775 D001943 denotes mammary cancer
T90 761-775 D001943 denotes mammary cancer
T91 780-789 SO:0000817 denotes wild-type
T92 790-794 PR:000005054 denotes mice
T94 790-794 O89094 denotes mice
T93 790-794 D051379 denotes mice
T95 790-794 10095 denotes mice
T96 846-853 GO:0003006 denotes puberty
T97 862-871 GO:0007595 denotes lactation
T98 941-946 UBERON:0001092 denotes atlas
T99 968-974 UBERON:0000479 denotes tissue
T100 1016-1027 UBERON:0002049 denotes vasculature
T101 1082-1092 SO:0000783 denotes engineered
T102 1093-1097 PR:000005054 denotes mice
T104 1093-1097 O89094 denotes mice
T103 1093-1097 D051379 denotes mice
T105 1093-1097 10095 denotes mice
T106 1138-1145 D009369 denotes cancers
T107 1138-1145 D009369 denotes cancers
T108 1260-1266 UBERON:0000479 denotes tissue
T111 1305-1308 GO:0005562 denotes RNA
T112 1305-1308 SO:0000356 denotes RNA
T109 1305-1308 CHEBI:33697 denotes RNA
T110 1305-1308 D012313 denotes RNA
T113 1421-1428 CHEBI:78310 denotes carmine
T114 1421-1428 D002329 denotes carmine
T115 1421-1428 D002329 denotes carmine
T116 1429-1433 C041524 denotes alum
T117 1429-1433 CHEBI:74768 denotes alum
T118 1429-1433 C041524 denotes alum
T119 1442-1455 UBERON:0001911 denotes mammary gland
T120 1442-1455 UBERON:0005200 denotes mammary gland
T122 1496-1507 D006416 denotes hematoxylin
T123 1496-1507 CHEBI:51686 denotes hematoxylin
T124 1496-1507 CHEBI:5601 denotes hematoxylin
T125 1496-1507 D006416 denotes hematoxylin
T126 1512-1517 1310593 denotes eosin
T127 1512-1517 D004801 denotes eosin
T128 1512-1517 D004801 denotes eosin
T129 1526-1532 UBERON:0000479 denotes tissue
T130 1648-1661 UBERON:0001911 denotes mammary gland
T131 1648-1661 UBERON:0005200 denotes mammary gland

UseCases_ArguminSci_Discourse

Id Subject Object Predicate Lexical cue
T1 0-167 DRI_Background denotes Reflectance confocal microscopy for characterization of mammary ductal structures and development of neoplasia in genetically engineered mouse models of breast cancer.
T2 168-255 DRI_Background denotes The earliest steps of breast cancer begin with aberrations in mammary ductal structure.
T3 256-470 DRI_Background denotes Techniques that enable an investigator to image in situ and then analyze the same tissue using biochemical tools facilitates identification of genetic networks and signaling pathways active in the imaged structure.
T4 471-776 DRI_Background denotes Cellular confocal microscopy (VivaCell-TiBa, Rochester, New York) is used to image mammary ductal structures and surrounding vasculature in situ in intact wild-type and genetically engineered mice that develop ER alpha-initiated ductal carcinoma in situ (DCIS) and ER alpha-driven invasive mammary cancer.
T5 777-958 DRI_Background denotes In wild-type mice, normal mammary ductal structures that appear from puberty through lactation are visualized and serially sectioned optically, and a developmental atlas is created.
T6 959-1062 DRI_Background denotes Altering tissue preparation enabled visualization of the vasculature surrounding the ductal structures.
T7 1063-1205 DRI_Background denotes In the genetically engineered mice, aberrant mammary ductal structures and cancers are imaged and compared to corresponding normal structures.
T8 1206-1319 DRI_Background denotes Different preparation techniques are able to preserve tissue for routine histological analyses and RNA isolation.
T9 1320-1542 DRI_Background denotes Comparative studies demonstrate that reflectance confocal imaging provides more cellular detail than carmine-alum-stained mammary gland whole mounts and equivalent detail with hematoxylin and eosin stained tissue sections.
T10 1543-1672 DRI_Challenge denotes In summary, reflectance confocal microscopy is a tool that can be used to rapidly and accurately analyze mammary gland structure.