PubMed:16219954 JSONTXT

{"project":"LitCoin-PubTator-for-Tuning","denotations":[{"id":"2","span":{"begin":32,"end":50},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3","span":{"begin":164,"end":171},"obj":"ChemicalEntity"},{"id":"13","span":{"begin":275,"end":293},"obj":"DiseaseOrPhenotypicFeature"},{"id":"14","span":{"begin":387,"end":395},"obj":"OrganismTaxon"},{"id":"15","span":{"begin":412,"end":420},"obj":"OrganismTaxon"},{"id":"16","span":{"begin":537,"end":544},"obj":"ChemicalEntity"},{"id":"17","span":{"begin":568,"end":575},"obj":"OrganismTaxon"},{"id":"18","span":{"begin":586,"end":596},"obj":"DiseaseOrPhenotypicFeature"},{"id":"19","span":{"begin":714,"end":722},"obj":"OrganismTaxon"},{"id":"20","span":{"begin":1286,"end":1294},"obj":"OrganismTaxon"},{"id":"21","span":{"begin":1332,"end":1353},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"MESH:D007495"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:D009369"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:C535434"},{"id":"A2","pred":"tao:has_database_id","subj":"2","obj":"MESH:D008048"},{"id":"A17","pred":"tao:has_database_id","subj":"17","obj":"Tax:9606"},{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"MESH:D007495"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:9606"},{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"Tax:9606"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"Tax:9606"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"Tax:9606"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"MESH:D008048"}],"text":"Curative radiotherapy for early cancers of the lip, buccal mucosa, and nose--a simple interstitial brachytherapy technique employing angiocatheters as carriers for Iridium-192 wire implants.\nOBJECTIVES: To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose.\nDESIGN: Retrospective study.\nSETTING: Regional hospital, Hong Kong.\nPATIENTS: A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carriers for Iridium-192 wires: all but one patient had T1 or T2 tumours and all but one had N0 disease.\nMAIN OUTCOME MEASURES: Local and loco-regional control rates.\nRESULTS: Six of the 13 patients received external radiotherapy prior to interstitial brachytherapy. A median brachytherapy dose of 70 Gy was delivered to those treated with brachytherapy alone, while 35 Gy was delivered after a median external radiotherapy dose of 50 Gy to those receiving combined treatment. The 3-year actuarial local control rate was 75%. No significant late complications were observed.\nCONCLUSIONS: Employing a simple brachytherapy technique using angiocatheters and Iridium-192 wires, in conjunction with external radiotherapy when appropriate, produces good outcomes for patients with early lip, nasal vestibule, and buccal mucosa cancers."}

{"project":"LitCoin-Disease-Tuning-1","denotations":[{"id":"T1","span":{"begin":32,"end":50},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":275,"end":293},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":589,"end":596},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":620,"end":627},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1346,"end":1353},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A3","pred":"ID:","subj":"T3","obj":"DISEASE"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D008048"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D008048"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D009369"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D004194"}],"text":"Curative radiotherapy for early cancers of the lip, buccal mucosa, and nose--a simple interstitial brachytherapy technique employing angiocatheters as carriers for Iridium-192 wire implants.\nOBJECTIVES: To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose.\nDESIGN: Retrospective study.\nSETTING: Regional hospital, Hong Kong.\nPATIENTS: A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carriers for Iridium-192 wires: all but one patient had T1 or T2 tumours and all but one had N0 disease.\nMAIN OUTCOME MEASURES: Local and loco-regional control rates.\nRESULTS: Six of the 13 patients received external radiotherapy prior to interstitial brachytherapy. A median brachytherapy dose of 70 Gy was delivered to those treated with brachytherapy alone, while 35 Gy was delivered after a median external radiotherapy dose of 50 Gy to those receiving combined treatment. The 3-year actuarial local control rate was 75%. No significant late complications were observed.\nCONCLUSIONS: Employing a simple brachytherapy technique using angiocatheters and Iridium-192 wires, in conjunction with external radiotherapy when appropriate, produces good outcomes for patients with early lip, nasal vestibule, and buccal mucosa cancers."}

{"project":"LitEisuke","denotations":[{"id":"T1","span":{"begin":32,"end":50},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":275,"end":293},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":589,"end":596},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1346,"end":1353},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D008048"},{"id":"A2","pred":"#label","subj":"T2","obj":"D008048"},{"id":"A3","pred":"#label","subj":"T3","obj":"DISEASE"},{"id":"A4","pred":"#label","subj":"T4","obj":"D009369"}],"text":"Curative radiotherapy for early cancers of the lip, buccal mucosa, and nose--a simple interstitial brachytherapy technique employing angiocatheters as carriers for Iridium-192 wire implants.\nOBJECTIVES: To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose.\nDESIGN: Retrospective study.\nSETTING: Regional hospital, Hong Kong.\nPATIENTS: A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carriers for Iridium-192 wires: all but one patient had T1 or T2 tumours and all but one had N0 disease.\nMAIN OUTCOME MEASURES: Local and loco-regional control rates.\nRESULTS: Six of the 13 patients received external radiotherapy prior to interstitial brachytherapy. A median brachytherapy dose of 70 Gy was delivered to those treated with brachytherapy alone, while 35 Gy was delivered after a median external radiotherapy dose of 50 Gy to those receiving combined treatment. The 3-year actuarial local control rate was 75%. No significant late complications were observed.\nCONCLUSIONS: Employing a simple brachytherapy technique using angiocatheters and Iridium-192 wires, in conjunction with external radiotherapy when appropriate, produces good outcomes for patients with early lip, nasal vestibule, and buccal mucosa cancers."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":275,"end":282},"obj":"HP_0002664"},{"id":"T2","span":{"begin":275,"end":293},"obj":"HP_0100604"}],"text":"Curative radiotherapy for early cancers of the lip, buccal mucosa, and nose--a simple interstitial brachytherapy technique employing angiocatheters as carriers for Iridium-192 wire implants.\nOBJECTIVES: To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose.\nDESIGN: Retrospective study.\nSETTING: Regional hospital, Hong Kong.\nPATIENTS: A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carriers for Iridium-192 wires: all but one patient had T1 or T2 tumours and all but one had N0 disease.\nMAIN OUTCOME MEASURES: Local and loco-regional control rates.\nRESULTS: Six of the 13 patients received external radiotherapy prior to interstitial brachytherapy. A median brachytherapy dose of 70 Gy was delivered to those treated with brachytherapy alone, while 35 Gy was delivered after a median external radiotherapy dose of 50 Gy to those receiving combined treatment. The 3-year actuarial local control rate was 75%. No significant late complications were observed.\nCONCLUSIONS: Employing a simple brachytherapy technique using angiocatheters and Iridium-192 wires, in conjunction with external radiotherapy when appropriate, produces good outcomes for patients with early lip, nasal vestibule, and buccal mucosa cancers."}