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PubMed:16208259 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-61 Sentence denotes [Intravenous ketoprofen for severe lithium-induced polyuria].
TextSentencer_T2 62-172 Sentence denotes Traitement par kétoprofène intraveineux d'une polyurie sévère survenue au cours d'une intoxication au lithium.
TextSentencer_T3 173-186 Sentence denotes INTRODUCTION:
TextSentencer_T4 187-327 Sentence denotes Although lithium has a narrow therapeutic range, it is widely used in psychiatry because of its antipsychotic and antidepressant properties.
TextSentencer_T5 328-512 Sentence denotes During long-term treatment, the onset of nephrogenic diabetes insipidus is common, but few cases of severe hypotonic polyuria, which would be an aggravating factor, have been reported.
TextSentencer_T6 513-569 Sentence denotes Appropriate treatment in such cases is an open question.
TextSentencer_T7 570-575 Sentence denotes CASE:
TextSentencer_T8 576-703 Sentence denotes We report a case of acute lithium poisoning in a 42-year-old man, due to chronic lithium treatment (plasma lithium=2.6 mmol/L).
TextSentencer_T9 704-864 Sentence denotes This patient, admitted to our intensive care unit, presented neurological disorders complicated by the early emergence of severe nephrogenic diabetes insipidus.
TextSentencer_T10 865-994 Sentence denotes After perfusion of hypotonic solution and intravenous treatment with ketoprofen (100 mg x 3/24 h), the polyuria improved rapidly.
TextSentencer_T11 995-1004 Sentence denotes COMMENTS:
TextSentencer_T12 1005-1124 Sentence denotes The beneficial action of nonsteroidal antiinflammatory drugs lies in their capacity to inhibit prostaglandin synthesis.
TextSentencer_T13 1125-1238 Sentence denotes Lithium causes excess production of prostaglandins, which decrease the ability of kidneys to reabsorb free water.
TextSentencer_T14 1239-1306 Sentence denotes Some publications report indomethacin to be effective in this case.
TextSentencer_T15 1307-1396 Sentence denotes Because it is available only in oral or rectal forms, however, its effect may be delayed.
TextSentencer_T16 1397-1563 Sentence denotes Our case suggests that intravenous ketoprofen, with its rapid onset of action, is effective in the treatment of severe lithium-induced nephrogenic diabetes insipidus.
TextSentencer_T17 1564-1691 Sentence denotes Rehydration must be strictly monitored because of the risk of renal failure connected with nonsteroidal antiinflammatory drugs.
T1 0-61 Sentence denotes [Intravenous ketoprofen for severe lithium-induced polyuria].
T2 62-172 Sentence denotes Traitement par kétoprofène intraveineux d'une polyurie sévère survenue au cours d'une intoxication au lithium.
T3 173-186 Sentence denotes INTRODUCTION:
T4 187-327 Sentence denotes Although lithium has a narrow therapeutic range, it is widely used in psychiatry because of its antipsychotic and antidepressant properties.
T5 328-512 Sentence denotes During long-term treatment, the onset of nephrogenic diabetes insipidus is common, but few cases of severe hypotonic polyuria, which would be an aggravating factor, have been reported.
T6 513-569 Sentence denotes Appropriate treatment in such cases is an open question.
T7 570-575 Sentence denotes CASE:
T8 576-703 Sentence denotes We report a case of acute lithium poisoning in a 42-year-old man, due to chronic lithium treatment (plasma lithium=2.6 mmol/L).
T9 704-864 Sentence denotes This patient, admitted to our intensive care unit, presented neurological disorders complicated by the early emergence of severe nephrogenic diabetes insipidus.
T10 865-994 Sentence denotes After perfusion of hypotonic solution and intravenous treatment with ketoprofen (100 mg x 3/24 h), the polyuria improved rapidly.
T11 995-1004 Sentence denotes COMMENTS:
T12 1005-1124 Sentence denotes The beneficial action of nonsteroidal antiinflammatory drugs lies in their capacity to inhibit prostaglandin synthesis.
T13 1125-1238 Sentence denotes Lithium causes excess production of prostaglandins, which decrease the ability of kidneys to reabsorb free water.
T14 1239-1306 Sentence denotes Some publications report indomethacin to be effective in this case.
T15 1307-1396 Sentence denotes Because it is available only in oral or rectal forms, however, its effect may be delayed.
T16 1397-1563 Sentence denotes Our case suggests that intravenous ketoprofen, with its rapid onset of action, is effective in the treatment of severe lithium-induced nephrogenic diabetes insipidus.
T17 1564-1691 Sentence denotes Rehydration must be strictly monitored because of the risk of renal failure connected with nonsteroidal antiinflammatory drugs.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 369-399 HP_0009806 denotes nephrogenic diabetes insipidus
T2 381-399 HP_0000873 denotes diabetes insipidus
T3 445-453 HP_0000103 denotes polyuria

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 51-59 HP:0000103 denotes polyuria
AB1 369-399 HP:0009806 denotes nephrogenic diabetes insipidus
AB2 445-453 HP:0000103 denotes polyuria
AB3 833-863 HP:0009806 denotes nephrogenic diabetes insipidus
AB4 968-976 HP:0000103 denotes polyuria
AB5 1532-1562 HP:0009806 denotes nephrogenic diabetes insipidus

PubCasesORDO

Id Subject Object Predicate Lexical cue
AB1 369-399 ORDO:223 denotes nephrogenic diabetes insipidus
AB2 833-863 ORDO:223 denotes nephrogenic diabetes insipidus
AB3 1532-1562 ORDO:223 denotes nephrogenic diabetes insipidus

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1207-1214 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys

QFMC_MEDLINE

Id Subject Object Predicate Lexical cue
T1 62-72 PROC denotes Traitement
T1c 62-72 UMLS:C0087111 denotes Traitement
T2 77-88 CHEM denotes kétoprofène
T2c 77-88 UMLS:C0022635 denotes kétoprofène
T3 108-116 DISO denotes polyurie
T3c 108-116 UMLS:C0032617 denotes polyurie
T4 148-171 DISO denotes intoxication au lithium
T4c 148-171 UMLS:C0568180 denotes intoxication au lithium
#1 T1 T1c Normalization Traitement,Traitement
#2 T2 T2c Normalization kétoprofène,kétoprofène
#3 T3 T3c Normalization polyurie,polyurie
#4 T4 T4c Normalization intoxication au lithium,intoxication au lithium