PubMed:16200390 / 399-750
Annnotations
LitCoin-sentences
{"project":"LitCoin-sentences","denotations":[{"id":"T4","span":{"begin":0,"end":351},"obj":"Sentence"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-entities-OrganismTaxon-PD
{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":219,"end":224},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:9606"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-entities
{"project":"LitCoin-entities","denotations":[{"id":"2395","span":{"begin":96,"end":100},"obj":"ChemicalEntity"},{"id":"2396","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2397","span":{"begin":219,"end":224},"obj":"OrganismTaxon"},{"id":"2398","span":{"begin":225,"end":247},"obj":"GeneOrGeneProduct"},{"id":"2399","span":{"begin":249,"end":252},"obj":"GeneOrGeneProduct"},{"id":"2400","span":{"begin":255,"end":279},"obj":"GeneOrGeneProduct"},{"id":"2401","span":{"begin":281,"end":285},"obj":"GeneOrGeneProduct"},{"id":"2402","span":{"begin":291,"end":310},"obj":"GeneOrGeneProduct"},{"id":"2403","span":{"begin":312,"end":316},"obj":"GeneOrGeneProduct"},{"id":"2404","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A9","pred":"db_id","subj":"2395","obj":"MESH:D012701"},{"id":"A10","pred":"db_id","subj":"2396","obj":"MESH:D008881"},{"id":"A11","pred":"db_id","subj":"2397","obj":"NCBITaxon:9606"},{"id":"A12","pred":"db_id","subj":"2398","obj":"NCBIGene:7166"},{"id":"A13","pred":"db_id","subj":"2399","obj":"NCBIGene:7166"},{"id":"A14","pred":"db_id","subj":"2400","obj":"NCBIGene:1644"},{"id":"A15","pred":"db_id","subj":"2401","obj":"NCBIGene:1644"},{"id":"A16","pred":"db_id","subj":"2402","obj":"NCBIGene:4128"},{"id":"A17","pred":"db_id","subj":"2403","obj":"NCBIGene:4128"},{"id":"A18","pred":"db_id","subj":"2404","obj":"MESH:D008881"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-GeneOrGeneProduct-v0
{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T9","span":{"begin":66,"end":73},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":96,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":101,"end":109},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":136,"end":144},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":225,"end":247},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":249,"end":252},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":255,"end":279},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":281,"end":285},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":291,"end":310},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":312,"end":316},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":327,"end":335},"obj":"GeneOrGeneProduct"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-GeneOrGeneProduct-v2
{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T6","span":{"begin":96,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":136,"end":144},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":225,"end":247},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":249,"end":252},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":255,"end":279},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":281,"end":285},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":291,"end":310},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":312,"end":316},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":327,"end":335},"obj":"GeneOrGeneProduct"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-Disease-MeSH
{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T5","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D008881"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D008881"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-GeneOrGeneProduct-v3
{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":225,"end":247},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":249,"end":252},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":255,"end":279},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":281,"end":285},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":291,"end":310},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":312,"end":316},"obj":"GeneOrGeneProduct"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin_Mondo_095
{"project":"LitCoin_Mondo_095","denotations":[{"id":"T6","span":{"begin":98,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0007699"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0005277"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"0005277"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-MeSH-Disease-2
{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T5","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"ID:","subj":"T5","obj":"D008881"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D008881"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-MONDO_bioort2019
{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T5","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"#label","subj":"T5","obj":"D008881"},{"id":"A6","pred":"#label","subj":"T6","obj":"D008881"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-Chemical-MeSH-CHEBI
{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T8","span":{"begin":96,"end":100},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":225,"end":247},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":249,"end":252},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":266,"end":279},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":291,"end":308},"obj":"ChemicalEntity"}],"attributes":[{"id":"A8","pred":"ID:","subj":"T8","obj":"D012701"},{"id":"A9","pred":"ID:","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_28790"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D014365"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D014365"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D002262"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D008995"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-NCBITaxon-2
{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":219,"end":224},"obj":"OrganismTaxon"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
LitCoin-training-merged
{"project":"LitCoin-training-merged","denotations":[{"id":"T13","span":{"begin":291,"end":308},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":266,"end":279},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":249,"end":252},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":225,"end":247},"obj":"ChemicalEntity"},{"id":"T8","span":{"begin":96,"end":100},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":312,"end":316},"obj":"GeneOrGeneProduct"},{"id":"T30007","span":{"begin":291,"end":310},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":281,"end":285},"obj":"GeneOrGeneProduct"},{"id":"T89820","span":{"begin":255,"end":279},"obj":"GeneOrGeneProduct"},{"id":"T95821","span":{"begin":249,"end":252},"obj":"GeneOrGeneProduct"},{"id":"T80664","span":{"begin":225,"end":247},"obj":"GeneOrGeneProduct"},{"id":"T32450","span":{"begin":327,"end":335},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T91210","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T46901","span":{"begin":219,"end":224},"obj":"OrganismTaxon"}],"attributes":[{"id":"A13","pred":"ID:","subj":"T13","obj":"D008995"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D002262"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D014365"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D014365"},{"id":"A9","pred":"ID:","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_28790"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D012701"},{"id":"A27522","pred":"#label","subj":"T32450","obj":"D008881"},{"id":"A1610","pred":"#label","subj":"T91210","obj":"D008881"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
PubmedHPO
{"project":"PubmedHPO","denotations":[{"id":"T4","span":{"begin":136,"end":144},"obj":"HP_0002076"},{"id":"T5","span":{"begin":327,"end":335},"obj":"HP_0002076"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}
DisGeNET
{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":291,"end":310},"obj":"gene:4128"},{"id":"T1","span":{"begin":136,"end":144},"obj":"disease:C0149931"},{"id":"T2","span":{"begin":291,"end":310},"obj":"gene:4128"},{"id":"T3","span":{"begin":327,"end":335},"obj":"disease:C0149931"},{"id":"T4","span":{"begin":312,"end":316},"obj":"gene:4128"},{"id":"T5","span":{"begin":327,"end":335},"obj":"disease:C0149931"},{"id":"T6","span":{"begin":312,"end":316},"obj":"gene:4128"},{"id":"T7","span":{"begin":136,"end":144},"obj":"disease:C0149931"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"With few genetic studies investigating biosynthetic and metabolic enzymes governing the rate of 5-HT activity and their relationship to migraine, it was the objective of this study to assess genetic variants within the human tryptophan hydroxylase (TPH), amino acid decarboxylase (AADC) and monoamine oxidase A (MAOA) genes in migraine susceptibility."}