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PubMed:1618911 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes Heterodimerization and transcriptional activation in vitro by NF-kappa B proteins.
T2 83-334 Sentence denotes The NF-kappa B family of transcription proteins represents multiple DNA binding, rel related polypeptides that contribute to regulation of genes involved in immune responsiveness and inflammation, as well as activation of the HIV long terminal repeat.
T3 335-700 Sentence denotes In this study multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa were examined for their capacity to interact with the PRDII regulatory element of interferon beta and were shown to possess distinct intrinsic DNA binding affinities for this NF-kappa B site and form multiple DNA binding homo- and heterodimer complexes in co-renaturation experiments.
T4 701-978 Sentence denotes Furthermore, using DNA templates containing two copies of the PRDII domain linked to the rabbit beta globin gene, the purified polypeptides specifically stimulated NF-kappa B dependent transcription in an in vitro reconstitution assay as heterodimers but not as p50 homodimers.
T5 979-1176 Sentence denotes These experiments emphasize the role of NF-kappa B dimerization as a distinct level of transcriptional control that may permit functional diversification of a limited number of regulatory proteins.
T1 0-82 Sentence denotes Heterodimerization and transcriptional activation in vitro by NF-kappa B proteins.
T2 83-334 Sentence denotes The NF-kappa B family of transcription proteins represents multiple DNA binding, rel related polypeptides that contribute to regulation of genes involved in immune responsiveness and inflammation, as well as activation of the HIV long terminal repeat.
T3 335-700 Sentence denotes In this study multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa were examined for their capacity to interact with the PRDII regulatory element of interferon beta and were shown to possess distinct intrinsic DNA binding affinities for this NF-kappa B site and form multiple DNA binding homo- and heterodimer complexes in co-renaturation experiments.
T4 701-978 Sentence denotes Furthermore, using DNA templates containing two copies of the PRDII domain linked to the rabbit beta globin gene, the purified polypeptides specifically stimulated NF-kappa B dependent transcription in an in vitro reconstitution assay as heterodimers but not as p50 homodimers.
T5 979-1176 Sentence denotes These experiments emphasize the role of NF-kappa B dimerization as a distinct level of transcriptional control that may permit functional diversification of a limited number of regulatory proteins.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 62-81 protein denotes NF-kappa B proteins
T2 87-104 protein denotes NF-kappa B family
T3 108-130 protein denotes transcription proteins
T4 164-188 protein denotes rel related polypeptides
T5 309-333 DNA denotes HIV long terminal repeat
T6 358-389 protein denotes NF-kappa B related polypeptides
T7 470-494 DNA denotes PRDII regulatory element
T8 498-513 DNA denotes interferon beta
T9 591-606 DNA denotes NF-kappa B site
T10 616-668 protein denotes multiple DNA binding homo- and heterodimer complexes
T11 720-733 DNA denotes DNA templates
T12 763-775 DNA denotes PRDII domain
T13 790-813 DNA denotes rabbit beta globin gene
T14 865-875 protein denotes NF-kappa B
T15 963-977 protein denotes p50 homodimers
T16 1019-1029 protein denotes NF-kappa B
T17 1156-1175 protein denotes regulatory proteins

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 62-81 NP denotes NF-kappa B proteins
C2 83-130 NP denotes The NF-kappa B family of transcription proteins
C3 142-188 NP denotes multiple DNA binding, rel related polypeptides
C4 189-193 NP denotes that
C5 349-415 NP denotes multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa
C6 434-439 NP denotes their
C7 466-513 NP denotes the PRDII regulatory element of interferon beta
C8 586-606 NP denotes this NF-kappa B site
C9 815-840 NP denotes the purified polypeptides
C10 1046-1089 NP denotes a distinct level of transcriptional control
C11 1090-1094 NP denotes that
R1 C2 C1 coref-other The NF-kappa B family of transcription proteins,NF-kappa B proteins
R2 C4 C3 coref-relat that,"multiple DNA binding, rel related polypeptides"
R3 C5 C3 coref-other multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa,"multiple DNA binding, rel related polypeptides"
R4 C6 C5 coref-other their,multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa
R5 C8 C7 coref-other this NF-kappa B site,the PRDII regulatory element of interferon beta
R6 C9 C5 coref-other the purified polypeptides,multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa
R7 C11 C10 coref-relat that,a distinct level of transcriptional control

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-82 Sentence denotes Heterodimerization and transcriptional activation in vitro by NF-kappa B proteins.
S2 83-334 Sentence denotes The NF-kappa B family of transcription proteins represents multiple DNA binding, rel related polypeptides that contribute to regulation of genes involved in immune responsiveness and inflammation, as well as activation of the HIV long terminal repeat.
S3 335-700 Sentence denotes In this study multiple NF-kappa B related polypeptides ranging from 85 to 45 kDa were examined for their capacity to interact with the PRDII regulatory element of interferon beta and were shown to possess distinct intrinsic DNA binding affinities for this NF-kappa B site and form multiple DNA binding homo- and heterodimer complexes in co-renaturation experiments.
S4 701-978 Sentence denotes Furthermore, using DNA templates containing two copies of the PRDII domain linked to the rabbit beta globin gene, the purified polypeptides specifically stimulated NF-kappa B dependent transcription in an in vitro reconstitution assay as heterodimers but not as p50 homodimers.
S5 979-1176 Sentence denotes These experiments emphasize the role of NF-kappa B dimerization as a distinct level of transcriptional control that may permit functional diversification of a limited number of regulatory proteins.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-18 other_name denotes Heterodimerization
T2 23-49 other_name denotes transcriptional activation
T3 62-72 protein_molecule denotes NF-kappa B
T4 87-97 protein_molecule denotes NF-kappa B
T5 108-130 protein_family_or_group denotes transcription proteins
T6 142-162 other_name denotes multiple DNA binding
T7 164-188 protein_family_or_group denotes rel related polypeptides
T8 240-261 other_name denotes immune responsiveness
T9 266-278 other_name denotes inflammation
T10 309-312 virus denotes HIV
T11 358-368 protein_molecule denotes NF-kappa B
T12 470-494 DNA_domain_or_region denotes PRDII regulatory element
T13 498-513 DNA_domain_or_region denotes interferon beta
T14 559-581 other_name denotes DNA binding affinities
T15 591-601 protein_molecule denotes NF-kappa B
T16 720-733 DNA_molecule denotes DNA templates
T17 763-775 DNA_family_or_group denotes PRDII domain
T18 790-813 DNA_family_or_group denotes rabbit beta globin gene
T19 819-840 peptide denotes purified polypeptides
T20 865-875 protein_molecule denotes NF-kappa B
T21 963-977 protein_subunit denotes p50 homodimers
T22 1019-1029 protein_molecule denotes NF-kappa B
T23 1066-1089 other_name denotes transcriptional control
T24 1106-1132 other_name denotes functional diversification
T25 1156-1175 protein_family_or_group denotes regulatory proteins