PubMed:16181814
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-127 | Sentence | denotes | Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome. |
| T2 | 128-246 | Sentence | denotes | Alpers syndrome is an autosomal recessive mitochondrial DNA depletion disorder that affects children and young adults. |
| T3 | 247-315 | Sentence | denotes | It is characterized by a progressive, fatal brain and liver disease. |
| T4 | 316-437 | Sentence | denotes | This syndrome has been associated with mutations in POLG, the gene encoding the mitochondrial DNA polymerase (pol gamma). |
| T5 | 438-580 | Sentence | denotes | Most patients with Alpers syndrome have been found to be compound heterozygotes, carrying two pathogenic mutations in trans at the POLG locus. |
| T6 | 581-720 | Sentence | denotes | POLG is a nuclear-encoded gene whose protein product is imported into mitochondria, where it is essential for mtDNA replication and repair. |
| T7 | 721-822 | Sentence | denotes | We studied the skin fibroblasts of a patient with Alpers syndrome having the genotype E873stop/A467T. |
| T8 | 823-901 | Sentence | denotes | The E873stop mutation produces a premature termination codon (TAG) in exon 17. |
| T9 | 902-1003 | Sentence | denotes | The A467T mutation produces a threonine to alanine substitution at a highly conserved site in exon 7. |
| T10 | 1004-1120 | Sentence | denotes | The allele bearing the stop codon (E873-TAG) is predicted to produce a truncated, catalytically inactive polymerase. |
| T11 | 1121-1203 | Sentence | denotes | However, only full-length pol gamma protein was detected by Western blot analysis. |
| T12 | 1204-1339 | Sentence | denotes | Here, we show that transcripts containing this stop codon undergo nonsense-associated alternative splicing and nonsense-mediated decay. |
| T13 | 1340-1486 | Sentence | denotes | More than 95% of the functional POLG mRNA was derived from the allele bearing the A467T mutation and less than 5% contained the E873stop mutation. |
| T14 | 1487-1588 | Sentence | denotes | These events ensured that virtually all POLG protein in the cell was expressed from the A467T allele. |
| T15 | 1589-1774 | Sentence | denotes | Therefore, the Alpers phenotype in this patient was a consequence of a single-copy gene dose of the A467T allele, and selective elimination of transcripts bearing the E873stop mutation. |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 878-883 | OrganismTaxon | denotes | codon | NCBItxid:79338 |
| T2 | 1032-1037 | OrganismTaxon | denotes | codon | NCBItxid:79338 |
| T3 | 1256-1261 | OrganismTaxon | denotes | codon | NCBItxid:79338 |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 2331 | 13-17 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2332 | 98-105 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 2333 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | MESH:D002549 |
| 2334 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | MESH:D002549 |
| 2335 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion | MESH:D028361 |
| 2336 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | MESH:D008107 |
| 2337 | 368-372 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2338 | 426-435 | GeneOrGeneProduct | denotes | pol gamma | NCBIGene:5428 |
| 2339 | 443-451 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 2340 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | MESH:D002549 |
| 2341 | 569-573 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2342 | 581-585 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2343 | 758-765 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 2344 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | MESH:D002549 |
| 2345 | 807-815 | SequenceVariant | denotes | E873stop | DBSNP:rs121918047 |
| 2346 | 816-821 | SequenceVariant | denotes | A467T | DBSNP:rs113994095 |
| 2347 | 827-835 | SequenceVariant | denotes | E873stop | DBSNP:rs121918047 |
| 2348 | 906-911 | SequenceVariant | denotes | A467T | DBSNP:rs113994095 |
| 2349 | 932-952 | SequenceVariant | denotes | threonine to alanine | DBSNP:rs113994095 |
| 2350 | 1039-1047 | SequenceVariant | denotes | E873-TAG | DBSNP:rs121918047 |
| 2351 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma | NCBIGene:5428 |
| 2352 | 1372-1376 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2353 | 1422-1427 | SequenceVariant | denotes | A467T | DBSNP:rs113994095 |
| 2354 | 1468-1476 | SequenceVariant | denotes | E873stop | DBSNP:rs121918047 |
| 2355 | 1527-1531 | GeneOrGeneProduct | denotes | POLG | NCBIGene:5428 |
| 2356 | 1575-1580 | SequenceVariant | denotes | A467T | DBSNP:rs113994095 |
| 2357 | 1629-1636 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 2358 | 1689-1694 | SequenceVariant | denotes | A467T | DBSNP:rs113994095 |
| 2359 | 1756-1764 | SequenceVariant | denotes | E873stop | DBSNP:rs121918047 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | 0005154 |
LitCoin-SeqVar
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 807-815 | SequenceVariant | denotes | E873stop |
| T2 | 816-821 | SequenceVariant | denotes | A467T |
| T3 | 827-835 | SequenceVariant | denotes | E873stop |
| T4 | 906-911 | SequenceVariant | denotes | A467T |
| T5 | 1422-1427 | SequenceVariant | denotes | A467T |
| T6 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T7 | 1575-1580 | SequenceVariant | denotes | A467T |
| T8 | 1689-1694 | SequenceVariant | denotes | A467T |
| T9 | 1756-1764 | SequenceVariant | denotes | E873stop |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | GeneOrGeneProduct | denotes | Mono |
| T2 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T3 | 53-61 | GeneOrGeneProduct | denotes | mediated |
| T4 | 62-67 | GeneOrGeneProduct | denotes | decay |
| T5 | 84-92 | GeneOrGeneProduct | denotes | splicing |
| T6 | 118-126 | GeneOrGeneProduct | denotes | syndrome |
| T7 | 135-143 | GeneOrGeneProduct | denotes | syndrome |
| T8 | 170-183 | GeneOrGeneProduct | denotes | mitochondrial |
| T9 | 188-197 | GeneOrGeneProduct | denotes | depletion |
| T10 | 233-238 | GeneOrGeneProduct | denotes | young |
| T11 | 291-296 | GeneOrGeneProduct | denotes | brain |
| T12 | 301-306 | GeneOrGeneProduct | denotes | liver |
| T13 | 321-329 | GeneOrGeneProduct | denotes | syndrome |
| T14 | 355-364 | GeneOrGeneProduct | denotes | mutations |
| T15 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T16 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T17 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T18 | 464-472 | GeneOrGeneProduct | denotes | syndrome |
| T19 | 543-552 | GeneOrGeneProduct | denotes | mutations |
| T20 | 553-561 | GeneOrGeneProduct | denotes | in trans |
| T21 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T22 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T23 | 618-625 | GeneOrGeneProduct | denotes | protein |
| T24 | 626-633 | GeneOrGeneProduct | denotes | product |
| T25 | 651-663 | GeneOrGeneProduct | denotes | mitochondria |
| T26 | 736-740 | GeneOrGeneProduct | denotes | skin |
| T27 | 778-786 | GeneOrGeneProduct | denotes | syndrome |
| T28 | 836-844 | GeneOrGeneProduct | denotes | mutation |
| T29 | 912-920 | GeneOrGeneProduct | denotes | mutation |
| T30 | 945-952 | GeneOrGeneProduct | denotes | alanine |
| T31 | 971-977 | GeneOrGeneProduct | denotes | highly |
| T32 | 978-987 | GeneOrGeneProduct | denotes | conserved |
| T33 | 1027-1031 | GeneOrGeneProduct | denotes | stop |
| T34 | 1052-1061 | GeneOrGeneProduct | denotes | predicted |
| T35 | 1075-1084 | GeneOrGeneProduct | denotes | truncated |
| T36 | 1086-1099 | GeneOrGeneProduct | denotes | catalytically |
| T37 | 1100-1108 | GeneOrGeneProduct | denotes | inactive |
| T38 | 1109-1119 | GeneOrGeneProduct | denotes | polymerase |
| T39 | 1135-1139 | GeneOrGeneProduct | denotes | full |
| T40 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T41 | 1157-1164 | GeneOrGeneProduct | denotes | protein |
| T42 | 1189-1193 | GeneOrGeneProduct | denotes | blot |
| T43 | 1223-1234 | GeneOrGeneProduct | denotes | transcripts |
| T44 | 1251-1255 | GeneOrGeneProduct | denotes | stop |
| T45 | 1302-1314 | GeneOrGeneProduct | denotes | splicing and |
| T46 | 1324-1332 | GeneOrGeneProduct | denotes | mediated |
| T47 | 1333-1338 | GeneOrGeneProduct | denotes | decay |
| T48 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T49 | 1377-1381 | GeneOrGeneProduct | denotes | mRNA |
| T50 | 1428-1436 | GeneOrGeneProduct | denotes | mutation |
| T51 | 1477-1485 | GeneOrGeneProduct | denotes | mutation |
| T52 | 1523-1526 | GeneOrGeneProduct | denotes | all |
| T53 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
| T54 | 1532-1539 | GeneOrGeneProduct | denotes | protein |
| T55 | 1547-1551 | GeneOrGeneProduct | denotes | cell |
| T56 | 1732-1743 | GeneOrGeneProduct | denotes | transcripts |
| T57 | 1765-1773 | GeneOrGeneProduct | denotes | mutation |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 62-67 | GeneOrGeneProduct | denotes | decay |
| T3 | 118-126 | GeneOrGeneProduct | denotes | syndrome |
| T4 | 135-143 | GeneOrGeneProduct | denotes | syndrome |
| T5 | 170-183 | GeneOrGeneProduct | denotes | mitochondrial |
| T6 | 233-238 | GeneOrGeneProduct | denotes | young |
| T7 | 291-296 | GeneOrGeneProduct | denotes | brain |
| T8 | 301-306 | GeneOrGeneProduct | denotes | liver |
| T9 | 321-329 | GeneOrGeneProduct | denotes | syndrome |
| T10 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T11 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T12 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T13 | 464-472 | GeneOrGeneProduct | denotes | syndrome |
| T14 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T15 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T16 | 618-625 | GeneOrGeneProduct | denotes | protein |
| T17 | 626-633 | GeneOrGeneProduct | denotes | product |
| T18 | 651-663 | GeneOrGeneProduct | denotes | mitochondria |
| T19 | 778-786 | GeneOrGeneProduct | denotes | syndrome |
| T20 | 945-952 | GeneOrGeneProduct | denotes | alanine |
| T21 | 978-987 | GeneOrGeneProduct | denotes | conserved |
| T22 | 1027-1031 | GeneOrGeneProduct | denotes | stop |
| T23 | 1075-1084 | GeneOrGeneProduct | denotes | truncated |
| T24 | 1100-1108 | GeneOrGeneProduct | denotes | inactive |
| T25 | 1109-1119 | GeneOrGeneProduct | denotes | polymerase |
| T26 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T27 | 1157-1164 | GeneOrGeneProduct | denotes | protein |
| T28 | 1189-1193 | GeneOrGeneProduct | denotes | blot |
| T29 | 1251-1255 | GeneOrGeneProduct | denotes | stop |
| T30 | 1333-1338 | GeneOrGeneProduct | denotes | decay |
| T31 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T32 | 1377-1381 | GeneOrGeneProduct | denotes | mRNA |
| T33 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
| T34 | 1532-1539 | GeneOrGeneProduct | denotes | protein |
| T35 | 1547-1551 | GeneOrGeneProduct | denotes | cell |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T2 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T3 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion | DISEASE |
| T4 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | D008107 |
| T5 | 321-329 | DiseaseOrPhenotypicFeature | denotes | syndrome | D013577 |
| T6 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T7 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T3 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T4 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T5 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T6 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T7 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T9 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-4 | DiseaseOrPhenotypicFeature | denotes | Mono | 0005810 |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | 0008758 |
| T3 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | 0008758 |
| T4 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | 0005154 |
| T5 | 321-329 | DiseaseOrPhenotypicFeature | denotes | syndrome | 0002254 |
| T6 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | 0008758 |
| T7 | 736-740 | DiseaseOrPhenotypicFeature | denotes | skin | 0002531 |
| T8 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | 0008758 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T2 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T3 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion | DISEASE |
| T4 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | D008107 |
| T5 | 321-329 | DiseaseOrPhenotypicFeature | denotes | syndrome | D013577 |
| T6 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T7 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T2 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T3 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion | DISEASE |
| T4 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | D008107 |
| T5 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
| T6 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 410-424 | ChemicalEntity | denotes | DNA polymerase | D004259 |
| T2 | 932-941 | ChemicalEntity | denotes | threonine | http://purl.obolibrary.org/obo/CHEBI_26986 |
| T3 | 945-952 | ChemicalEntity | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 98-105 | OrganismTaxon | denotes | patient |
| T2 | 443-451 | OrganismTaxon | denotes | patients |
| T3 | 758-765 | OrganismTaxon | denotes | patient |
| T4 | 1629-1636 | OrganismTaxon | denotes | patient |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T3 | 945-952 | ChemicalEntity | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 | |
| T2 | 932-941 | ChemicalEntity | denotes | threonine | http://purl.obolibrary.org/obo/CHEBI_26986 | |
| T1 | 410-424 | ChemicalEntity | denotes | DNA polymerase | D004259 | |
| T9 | 1527-1531 | GeneOrGeneProduct | denotes | POLG | ||
| T8 | 1372-1376 | GeneOrGeneProduct | denotes | POLG | ||
| T7 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma | ||
| T6 | 581-585 | GeneOrGeneProduct | denotes | POLG | ||
| T5 | 569-573 | GeneOrGeneProduct | denotes | POLG | ||
| T4 | 426-435 | GeneOrGeneProduct | denotes | pol gamma | ||
| T6013 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase | ||
| T29019 | 368-372 | GeneOrGeneProduct | denotes | POLG | ||
| T3983 | 13-17 | GeneOrGeneProduct | denotes | POLG | ||
| T94004 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 | |
| T22101 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 | |
| T96460 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease | D008107 | |
| T37509 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion | DISEASE | |
| T25423 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 | |
| T73252 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome | D002549 | |
| T15051 | 1629-1636 | OrganismTaxon | denotes | patient | ||
| T69776 | 758-765 | OrganismTaxon | denotes | patient | ||
| T66514 | 443-451 | OrganismTaxon | denotes | patients | ||
| T53321 | 98-105 | OrganismTaxon | denotes | patient | ||
| T89866 | 1756-1764 | SequenceVariant | denotes | E873stop | ||
| T71980 | 1689-1694 | SequenceVariant | denotes | A467T | ||
| T2663 | 1575-1580 | SequenceVariant | denotes | A467T | ||
| T18412 | 1468-1476 | SequenceVariant | denotes | E873stop | ||
| T5305 | 1422-1427 | SequenceVariant | denotes | A467T | ||
| T81214 | 906-911 | SequenceVariant | denotes | A467T | ||
| T56637 | 827-835 | SequenceVariant | denotes | E873stop | ||
| T2202 | 816-821 | SequenceVariant | denotes | A467T | ||
| T36131 | 807-815 | SequenceVariant | denotes | E873stop |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 16181814-0#13#17#gene5428 | 13-17 | gene5428 | denotes | POLG |
| 16181814-0#111#126#diseaseC0007795 | 111-126 | diseaseC0007795 | denotes | Alpers syndrome |
| 16181814-0#111#126#diseaseC0205710 | 111-126 | diseaseC0205710 | denotes | Alpers syndrome |
| 13#17#gene5428111#126#diseaseC0007795 | 16181814-0#13#17#gene5428 | 16181814-0#111#126#diseaseC0007795 | associated_with | POLG,Alpers syndrome |
| 13#17#gene5428111#126#diseaseC0205710 | 16181814-0#13#17#gene5428 | 16181814-0#111#126#diseaseC0205710 | associated_with | POLG,Alpers syndrome |
tmVarCorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 807-815 | ProteinMutation:p|SUB|E|873|X | denotes | E873stop |
| T2 | 816-821 | ProteinMutation:p|SUB|A|467|T | denotes | A467T |
| T3 | 827-835 | ProteinMutation:p|SUB|E|873|X | denotes | E873stop |
| T4 | 906-911 | ProteinMutation:p|SUB|A|467|T | denotes | A467T |
| T5 | 1039-1047 | ProteinMutation:p|SUB|E|873|X | denotes | E873-TAG |
| T6 | 1422-1427 | ProteinMutation:p|SUB|A|467|T | denotes | A467T |
| T7 | 1468-1476 | ProteinMutation:p|SUB|E|873|X | denotes | E873stop |
| T8 | 1575-1580 | ProteinMutation:p|SUB|A|467|T | denotes | A467T |
| T9 | 1689-1694 | ProteinMutation:p|SUB|A|467|T | denotes | A467T |
| T10 | 1756-1764 | ProteinMutation:p|SUB|E|873|X | denotes | E873stop |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 13-17 | gene:5428 | denotes | POLG |
| T1 | 111-126 | disease:C0007795 | denotes | Alpers syndrome |
| T2 | 13-17 | gene:5428 | denotes | POLG |
| T3 | 111-126 | disease:C0205710 | denotes | Alpers syndrome |
| R1 | T0 | T1 | associated_with | POLG,Alpers syndrome |
| R2 | T2 | T3 | associated_with | POLG,Alpers syndrome |
biored-valid-deepseek-nr-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-28 | GeneOrGeneProduct | denotes | Mono-allelic POLG expression |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T5 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T6 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T7 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T8 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 98-105 | OrganismTaxon | denotes | patient |
| T3 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T5 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion |
| T6 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease |
| T7 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T8 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T9 | 443-451 | OrganismTaxon | denotes | patients |
| T10 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T11 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T12 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T13 | 758-765 | OrganismTaxon | denotes | patient |
| T14 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T15 | 807-815 | SequenceVariant | denotes | E873stop |
| T16 | 816-821 | SequenceVariant | denotes | A467T |
| T17 | 827-835 | SequenceVariant | denotes | E873stop |
| T18 | 906-911 | SequenceVariant | denotes | A467T |
| T19 | 932-952 | SequenceVariant | denotes | threonine to alanine |
| T20 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T21 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T22 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T23 | 1422-1427 | SequenceVariant | denotes | A467T |
| T24 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T25 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
| T26 | 1575-1580 | SequenceVariant | denotes | A467T |
| T27 | 1629-1636 | OrganismTaxon | denotes | patient |
| T28 | 1689-1694 | SequenceVariant | denotes | A467T |
| T29 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-deepseek-nr-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | ChemicalEntity | denotes | Mono |
| T2 | 5-12 | SequenceVariant | denotes | allelic |
| T3 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T4 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T5 | 150-169 | DiseaseOrPhenotypicFeature | denotes | autosomal recessive |
| T6 | 170-197 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion |
| T7 | 198-206 | DiseaseOrPhenotypicFeature | denotes | disorder |
| T8 | 301-306 | DiseaseOrPhenotypicFeature | denotes | liver |
| T9 | 307-314 | DiseaseOrPhenotypicFeature | denotes | disease |
| T10 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T11 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T12 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T13 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T14 | 581-585 | GeneOrGeneProduct | denotes | POLG |
| T15 | 618-625 | GeneOrGeneProduct | denotes | protein |
| T16 | 691-708 | GeneOrGeneProduct | denotes | mtDNA replication |
| T17 | 713-719 | GeneOrGeneProduct | denotes | repair |
| T18 | 807-815 | SequenceVariant | denotes | E873stop |
| T19 | 816-821 | SequenceVariant | denotes | A467T |
| T20 | 827-835 | SequenceVariant | denotes | E873stop |
| T21 | 885-888 | SequenceVariant | denotes | TAG |
| T22 | 906-911 | SequenceVariant | denotes | A467T |
| T23 | 932-941 | ChemicalEntity | denotes | threonine |
| T24 | 945-952 | ChemicalEntity | denotes | alanine |
| T25 | 996-1002 | SequenceVariant | denotes | exon 7 |
| T26 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T27 | 1157-1164 | GeneOrGeneProduct | denotes | protein |
| T28 | 1377-1381 | GeneOrGeneProduct | denotes | mRNA |
| T29 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-deepseek-r-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T5 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T6 | 807-815 | SequenceVariant | denotes | E873stop |
| T7 | 816-821 | SequenceVariant | denotes | A467T |
| T8 | 885-888 | ChemicalEntity | denotes | TAG |
| T9 | 932-941 | ChemicalEntity | denotes | threonine |
| T10 | 945-952 | ChemicalEntity | denotes | alanine |
| T11 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T12 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T13 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T14 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-deepseek-r-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T4 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T5 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T6 | 807-815 | SequenceVariant | denotes | E873stop |
| T7 | 816-821 | SequenceVariant | denotes | A467T |
| T8 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T9 | 1147-1164 | GeneOrGeneProduct | denotes | pol gamma protein |
| T10 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T11 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T12 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-gemini-nr-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 150-169 | DiseaseOrPhenotypicFeature | denotes | autosomal recessive |
| T4 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T5 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease |
| T6 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T7 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T9 | 736-752 | CellLine | denotes | skin fibroblasts |
| T10 | 807-815 | SequenceVariant | denotes | E873stop |
| T11 | 816-821 | SequenceVariant | denotes | A467T |
| T12 | 827-835 | SequenceVariant | denotes | E873stop |
| T13 | 906-911 | SequenceVariant | denotes | A467T |
| T14 | 932-941 | ChemicalEntity | denotes | threonine |
| T15 | 945-952 | ChemicalEntity | denotes | alanine |
| T16 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T17 | 1109-1119 | GeneOrGeneProduct | denotes | polymerase |
| T18 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T19 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T20 | 1422-1427 | SequenceVariant | denotes | A467T |
| T21 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T22 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-gemini-r-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 150-206 | DiseaseOrPhenotypicFeature | denotes | autosomal recessive mitochondrial DNA depletion disorder |
| T4 | 291-314 | DiseaseOrPhenotypicFeature | denotes | brain and liver disease |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T7 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T9 | 495-517 | DiseaseOrPhenotypicFeature | denotes | compound heterozygotes |
| T10 | 569-579 | GeneOrGeneProduct | denotes | POLG locus |
| T11 | 691-696 | ChemicalEntity | denotes | mtDNA |
| T12 | 736-752 | CellLine | denotes | skin fibroblasts |
| T13 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T14 | 807-821 | SequenceVariant | denotes | E873stop/A467T |
| T15 | 827-844 | SequenceVariant | denotes | E873stop mutation |
| T16 | 856-883 | SequenceVariant | denotes | premature termination codon |
| T17 | 885-888 | ChemicalEntity | denotes | TAG |
| T18 | 906-920 | SequenceVariant | denotes | A467T mutation |
| T19 | 932-941 | ChemicalEntity | denotes | threonine |
| T20 | 945-952 | ChemicalEntity | denotes | alanine |
| T21 | 1027-1037 | SequenceVariant | denotes | stop codon |
| T22 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T23 | 1109-1119 | GeneOrGeneProduct | denotes | polymerase |
| T24 | 1147-1164 | GeneOrGeneProduct | denotes | pol gamma protein |
| T25 | 1251-1261 | SequenceVariant | denotes | stop codon |
| T26 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T27 | 1422-1436 | SequenceVariant | denotes | A467T mutation |
| T28 | 1468-1485 | SequenceVariant | denotes | E873stop mutation |
| T29 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T30 | 1575-1587 | GeneOrGeneProduct | denotes | A467T allele |
| T31 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
| T32 | 1756-1773 | SequenceVariant | denotes | E873stop mutation |
biored-valid-gemini-r-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 150-206 | DiseaseOrPhenotypicFeature | denotes | autosomal recessive mitochondrial DNA depletion disorder |
| T4 | 291-314 | DiseaseOrPhenotypicFeature | denotes | brain and liver disease |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T7 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T9 | 807-821 | SequenceVariant | denotes | E873stop/A467T |
| T10 | 827-844 | SequenceVariant | denotes | E873stop mutation |
| T11 | 906-920 | SequenceVariant | denotes | A467T mutation |
| T12 | 932-965 | SequenceVariant | denotes | threonine to alanine substitution |
| T13 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T14 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T15 | 1468-1485 | SequenceVariant | denotes | E873stop mutation |
| T16 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T17 | 1575-1587 | SequenceVariant | denotes | A467T allele |
| T18 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-gpt-nr-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T4 | 291-314 | DiseaseOrPhenotypicFeature | denotes | brain and liver disease |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T7 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T8 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T9 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T10 | 807-815 | SequenceVariant | denotes | E873stop |
| T11 | 816-821 | SequenceVariant | denotes | A467T |
| T12 | 906-911 | SequenceVariant | denotes | A467T |
| T13 | 932-941 | ChemicalEntity | denotes | threonine |
| T14 | 945-952 | ChemicalEntity | denotes | alanine |
| T15 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T16 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T17 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T18 | 1422-1427 | SequenceVariant | denotes | A467T |
| T19 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T20 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T21 | 1575-1580 | SequenceVariant | denotes | A467T |
| T22 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
| T23 | 1689-1694 | SequenceVariant | denotes | A467T |
| T24 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-gpt-r-ng
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 170-187 | ChemicalEntity | denotes | mitochondrial DNA |
| T4 | 291-314 | DiseaseOrPhenotypicFeature | denotes | brain and liver disease |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 396-413 | ChemicalEntity | denotes | mitochondrial DNA |
| T7 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T9 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T10 | 691-696 | ChemicalEntity | denotes | mtDNA |
| T11 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T12 | 807-815 | SequenceVariant | denotes | E873stop |
| T13 | 816-821 | SequenceVariant | denotes | A467T |
| T14 | 906-911 | SequenceVariant | denotes | A467T |
| T15 | 932-941 | ChemicalEntity | denotes | threonine |
| T16 | 945-952 | ChemicalEntity | denotes | alanine |
| T17 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T18 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T19 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T20 | 1422-1427 | SequenceVariant | denotes | A467T |
| T21 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T22 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T23 | 1575-1580 | SequenceVariant | denotes | A467T |
| T24 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
| T25 | 1689-1694 | SequenceVariant | denotes | A467T |
| T26 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-gpt-nr-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T4 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T5 | 396-436 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase (pol gamma) |
| T6 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T7 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T8 | 807-821 | SequenceVariant | denotes | E873stop/A467T |
| T9 | 906-911 | SequenceVariant | denotes | A467T |
| T10 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T11 | 1147-1164 | GeneOrGeneProduct | denotes | pol gamma protein |
| T12 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T13 | 1422-1427 | SequenceVariant | denotes | A467T |
| T14 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T15 | 1527-1539 | GeneOrGeneProduct | denotes | POLG protein |
| T16 | 1575-1580 | SequenceVariant | denotes | A467T |
| T17 | 1689-1694 | SequenceVariant | denotes | A467T |
| T18 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-gpt-r-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T4 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T5 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T6 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T7 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T8 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T9 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T10 | 807-815 | SequenceVariant | denotes | E873stop |
| T11 | 816-821 | SequenceVariant | denotes | A467T |
| T12 | 906-911 | SequenceVariant | denotes | A467T |
| T13 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T14 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T15 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T16 | 1422-1427 | SequenceVariant | denotes | A467T |
| T17 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T18 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
| T19 | 1575-1580 | SequenceVariant | denotes | A467T |
| T20 | 1689-1694 | SequenceVariant | denotes | A467T |
| T21 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-gemini-nr-g
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 150-206 | DiseaseOrPhenotypicFeature | denotes | autosomal recessive mitochondrial DNA depletion disorder |
| T4 | 301-314 | DiseaseOrPhenotypicFeature | denotes | liver disease |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T7 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T8 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T9 | 736-752 | CellLine | denotes | skin fibroblasts |
| T10 | 807-815 | SequenceVariant | denotes | E873stop |
| T11 | 816-821 | SequenceVariant | denotes | A467T |
| T12 | 827-835 | SequenceVariant | denotes | E873stop |
| T13 | 906-911 | SequenceVariant | denotes | A467T |
| T14 | 932-941 | ChemicalEntity | denotes | threonine |
| T15 | 945-952 | ChemicalEntity | denotes | alanine |
| T16 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T17 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T18 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T19 | 1422-1427 | SequenceVariant | denotes | A467T |
| T20 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T21 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
biored-valid-gpt-r-m
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 98-105 | OrganismTaxon | denotes | patient |
| T3 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T5 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T6 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T7 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T8 | 443-451 | OrganismTaxon | denotes | patients |
| T9 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T10 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T11 | 758-765 | OrganismTaxon | denotes | patient |
| T12 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T13 | 807-821 | SequenceVariant | denotes | E873stop/A467T |
| T14 | 906-911 | SequenceVariant | denotes | A467T |
| T15 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T16 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T17 | 1372-1376 | GeneOrGeneProduct | denotes | POLG |
| T18 | 1422-1427 | SequenceVariant | denotes | A467T |
| T19 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T20 | 1527-1531 | GeneOrGeneProduct | denotes | POLG |
| T21 | 1575-1580 | SequenceVariant | denotes | A467T |
| T22 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
| T23 | 1629-1636 | OrganismTaxon | denotes | patient |
| T24 | 1689-1694 | SequenceVariant | denotes | A467T |
| T25 | 1756-1764 | SequenceVariant | denotes | E873stop |
biored-valid-gemini-r-m
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 98-105 | OrganismTaxon | denotes | patient |
| T3 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 170-206 | DiseaseOrPhenotypicFeature | denotes | mitochondrial DNA depletion disorder |
| T5 | 220-228 | OrganismTaxon | denotes | children |
| T6 | 233-245 | OrganismTaxon | denotes | young adults |
| T7 | 291-314 | DiseaseOrPhenotypicFeature | denotes | brain and liver disease |
| T8 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T9 | 396-424 | GeneOrGeneProduct | denotes | mitochondrial DNA polymerase |
| T10 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T11 | 443-451 | OrganismTaxon | denotes | patients |
| T12 | 457-472 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T13 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T14 | 741-752 | CellLine | denotes | fibroblasts |
| T15 | 758-765 | OrganismTaxon | denotes | patient |
| T16 | 771-786 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T17 | 807-815 | SequenceVariant | denotes | E873stop |
| T18 | 816-821 | SequenceVariant | denotes | A467T |
| T19 | 932-965 | SequenceVariant | denotes | threonine to alanine substitution |
| T20 | 1039-1047 | SequenceVariant | denotes | E873-TAG |
| T21 | 1147-1156 | GeneOrGeneProduct | denotes | pol gamma |
| T22 | 1372-1381 | GeneOrGeneProduct | denotes | POLG mRNA |
| T23 | 1422-1427 | SequenceVariant | denotes | A467T |
| T24 | 1468-1476 | SequenceVariant | denotes | E873stop |
| T25 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |
| T26 | 1629-1636 | OrganismTaxon | denotes | patient |
biored-valid-deepseek-r-m
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 13-17 | GeneOrGeneProduct | denotes | POLG |
| T2 | 111-126 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T3 | 128-143 | DiseaseOrPhenotypicFeature | denotes | Alpers syndrome |
| T4 | 368-372 | GeneOrGeneProduct | denotes | POLG |
| T5 | 426-435 | GeneOrGeneProduct | denotes | pol gamma |
| T6 | 569-573 | GeneOrGeneProduct | denotes | POLG |
| T7 | 807-815 | SequenceVariant | denotes | E873stop |
| T8 | 816-821 | SequenceVariant | denotes | A467T |
| T9 | 885-888 | SequenceVariant | denotes | TAG |
| T10 | 1604-1620 | DiseaseOrPhenotypicFeature | denotes | Alpers phenotype |