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PubMed:16177264 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 911-917 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T2 1028-1039 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 1541-1555 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl-Lewis x

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 911-917 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO
T2 1028-1039 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T3 1541-1555 Glycan_Motif denotes sialyl-Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T4 1548-1555 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 1541-1555 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl-Lewis x
T2 1548-1555 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
TextSentencer_T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
TextSentencer_T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
TextSentencer_T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
TextSentencer_T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
TextSentencer_T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
TextSentencer_T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
TextSentencer_T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
TextSentencer_T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
TextSentencer_T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 911-917 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T2 1028-1039 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 1541-1555 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl-Lewis x
T4 1548-1555 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T5 1548-1555 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 31-39 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T2 62-70 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T3 118-126 http://purl.obolibrary.org/obo/MAT_0000078 denotes Prostate
T4 187-195 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T5 271-279 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T6 532-540 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T7 1772-1780 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 155-160 HP_0002664 denotes tumor
T2 187-202 HP_0012125 denotes prostate cancer
T3 196-202 HP_0002664 denotes cancer
T4 264-291 HP_0008711 denotes benign prostate hyperplasia
T5 342-348 HP_0002664 denotes tumors
T6 526-531 HP_0002664 denotes tumor
T7 526-540 HP_0012125 denotes tumor prostate
T8 1346-1351 HP_0002664 denotes tumor

ICD10

Id Subject Object Predicate Lexical cue
T1 271-291 http://purl.bioontology.org/ontology/ICD10/N40 denotes prostate hyperplasia

uniprot-human

Id Subject Object Predicate Lexical cue
T1 31-56 http://www.uniprot.org/uniprot/P07288 denotes prostate-specific antigen
T2 113-116 http://www.uniprot.org/uniprot/P07288 denotes PSA
T3 145-148 http://www.uniprot.org/uniprot/P07288 denotes PSA
T4 412-415 http://www.uniprot.org/uniprot/P07288 denotes PSA
T5 506-509 http://www.uniprot.org/uniprot/P07288 denotes PSA
T6 592-595 http://www.uniprot.org/uniprot/P07288 denotes PSA
T7 687-690 http://www.uniprot.org/uniprot/P07288 denotes PSA
T8 797-800 http://www.uniprot.org/uniprot/P07288 denotes PSA
T9 838-841 http://www.uniprot.org/uniprot/P07288 denotes PSA
T10 902-905 http://www.uniprot.org/uniprot/P07288 denotes PSA
T11 929-932 http://www.uniprot.org/uniprot/P07288 denotes PSA
T12 1077-1080 http://www.uniprot.org/uniprot/P07288 denotes PSA
T13 1609-1612 http://www.uniprot.org/uniprot/P07288 denotes PSA
T14 31-56 http://www.uniprot.org/uniprot/Q16305 denotes prostate-specific antigen
T15 118-143 http://www.uniprot.org/uniprot/Q16305 denotes Prostate-specific antigen
T16 113-116 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T17 145-148 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T18 412-415 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T19 506-509 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T20 592-595 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T21 687-690 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T22 797-800 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T23 838-841 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T24 902-905 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T25 929-932 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T26 1077-1080 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T27 1609-1612 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T28 113-116 http://www.uniprot.org/uniprot/P55786 denotes PSA
T29 145-148 http://www.uniprot.org/uniprot/P55786 denotes PSA
T30 412-415 http://www.uniprot.org/uniprot/P55786 denotes PSA
T31 506-509 http://www.uniprot.org/uniprot/P55786 denotes PSA
T32 592-595 http://www.uniprot.org/uniprot/P55786 denotes PSA
T33 687-690 http://www.uniprot.org/uniprot/P55786 denotes PSA
T34 797-800 http://www.uniprot.org/uniprot/P55786 denotes PSA
T35 838-841 http://www.uniprot.org/uniprot/P55786 denotes PSA
T36 902-905 http://www.uniprot.org/uniprot/P55786 denotes PSA
T37 929-932 http://www.uniprot.org/uniprot/P55786 denotes PSA
T38 1077-1080 http://www.uniprot.org/uniprot/P55786 denotes PSA
T39 1609-1612 http://www.uniprot.org/uniprot/P55786 denotes PSA

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 113-116 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T2 145-148 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T3 412-415 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T4 506-509 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T5 592-595 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T6 687-690 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T7 797-800 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T8 838-841 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T9 902-905 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T10 929-932 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T11 1077-1080 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T12 1609-1612 http://www.uniprot.org/uniprot/Q11011 denotes PSA

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 71-77 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T2 86-94 http://purl.bioontology.org/ontology/NCBITAXON/353209 denotes relation
T3 196-202 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T4 1140-1145 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 78-82 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T2 704-708 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T3 1108-1112 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T4 1630-1634 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T5 395-408 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 489-502 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T7 766-779 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T8 1060-1073 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T9 1192-1205 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T10 1307-1320 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T11 1592-1605 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T12 510-518 http://purl.obolibrary.org/obo/GO_0046903 denotes secreted
T13 1541-1547 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl

GO-CC

Id Subject Object Predicate Lexical cue
T1 541-545 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 857-861 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1140-1145 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 791-796 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2 954-959 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T3 1373-1378 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T4 1466-1471 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T5 1493-1498 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 31-39 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T2 62-70 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T3 118-126 http://purl.obolibrary.org/obo/MAT_0000078 denotes Prostate
T4 187-195 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T5 271-279 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T6 532-540 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T7 1772-1780 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 1541-1553 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl-Lewis
T2 1541-1555 http://rdf.glycoinfo.org/glycan/G00054MO denotes sialyl-Lewis x
T3 1548-1553 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T4 1548-1555 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 113-116 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T2 145-148 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T3 412-415 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T4 506-509 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T5 592-595 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T6 687-690 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T7 797-800 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T8 838-841 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T9 902-905 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T10 929-932 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T11 1077-1080 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T12 1609-1612 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 1548-1555 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T2 1541-1553 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl-Lewis
PD-GlycoEpitope-B_T3 1541-1555 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl-Lewis x

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 791-796 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T2 954-959 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T3 1373-1378 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T4 1466-1471 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T5 1493-1498 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 62-77 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 155-160 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 187-202 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T4 204-207 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T5 256-259 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T6 264-291 Disease denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/MONDO_0010811
T7 293-296 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T8 342-348 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070
T9 522-540 Disease denotes the tumor prostate http://purl.obolibrary.org/obo/MONDO_0008315
T10 526-540 Disease denotes tumor prostate http://purl.obolibrary.org/obo/MONDO_0021259
T11 714-717 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T12 787-790 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T13 942-945 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T14 1094-1097 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T15 1346-1351 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T16 1454-1457 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T17 1618-1621 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T18 1626-1629 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 31-39 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 62-70 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T3 118-126 Body_part denotes Prostate http://purl.obolibrary.org/obo/MAT_0000078
T4 187-195 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T5 271-279 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T6 532-540 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T7 1772-1780 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 62-77 Phenotype denotes prostate cancer HP:0012125
T2 155-160 Phenotype denotes tumor HP:0002664
T3 187-202 Phenotype denotes prostate cancer HP:0012125
T4 204-207 Phenotype denotes PCa HP:0012125
T5 256-259 Phenotype denotes PCa HP:0012125
T6 264-291 Phenotype denotes benign prostate hyperplasia HP:0008711
T7 293-296 Phenotype denotes BPH HP:0008711
T8 526-531 Phenotype denotes tumor HP:0002664
T9 714-717 Phenotype denotes PCa HP:0012125
T10 787-790 Phenotype denotes PCa HP:0012125
T11 942-945 Phenotype denotes PCa HP:0012125
T12 1094-1097 Phenotype denotes PCa HP:0012125
T13 1346-1351 Phenotype denotes tumor HP:0002664
T14 1454-1457 Phenotype denotes PCa HP:0012125
T15 1618-1621 Phenotype denotes PCa HP:0012125
T16 1626-1629 Phenotype denotes BPH HP:0008711

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1541-1555 Glycan denotes sialyl-Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1541-1555 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl-Lewis x http://www.glycoepitope.jp/epitopes/EP0012

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 62-77 Phenotype denotes prostate cancer HP:0012125
T2 155-160 Phenotype denotes tumor HP:0002664
T3 187-202 Phenotype denotes prostate cancer HP:0012125
T4 204-207 Phenotype denotes PCa HP:0012125
T5 256-259 Phenotype denotes PCa HP:0012125
T6 264-291 Phenotype denotes benign prostate hyperplasia HP:0008711
T7 293-296 Phenotype denotes BPH HP:0008711
T8 526-531 Phenotype denotes tumor HP:0002664
T9 714-717 Phenotype denotes PCa HP:0012125
T10 787-790 Phenotype denotes PCa HP:0012125
T11 942-945 Phenotype denotes PCa HP:0012125
T12 1094-1097 Phenotype denotes PCa HP:0012125
T13 1346-1351 Phenotype denotes tumor HP:0002664
T14 1454-1457 Phenotype denotes PCa HP:0012125
T15 1618-1621 Phenotype denotes PCa HP:0012125
T16 1626-1629 Phenotype denotes BPH HP:0008711

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 62-77 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 155-160 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 187-202 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T4 204-207 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T5 256-259 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T6 264-291 Disease denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/MONDO_0010811
T7 293-296 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T8 342-348 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070
T9 522-540 Disease denotes the tumor prostate http://purl.obolibrary.org/obo/MONDO_0008315
T10 526-540 Disease denotes tumor prostate http://purl.obolibrary.org/obo/MONDO_0021259
T11 714-717 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T12 787-790 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T13 942-945 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T14 1094-1097 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T15 1346-1351 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T16 1454-1457 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T17 1618-1621 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T18 1626-1629 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 946-953 OrganismTaxon denotes patient 9606
T2 1458-1465 OrganismTaxon denotes patient 9606

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 31-39 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 62-70 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T3 98-112 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T4 118-126 Body_part denotes Prostate http://purl.obolibrary.org/obo/UBERON_0002367
T5 187-195 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T6 271-279 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T7 532-540 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T8 601-615 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T9 887-901 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T10 1114-1128 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T11 1772-1780 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 31-39 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 62-70 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T3 118-126 Body_part denotes Prostate http://purl.obolibrary.org/obo/MAT_0000078
T4 187-195 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T5 271-279 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T6 532-540 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T7 1772-1780 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
TextSentencer_T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
TextSentencer_T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
TextSentencer_T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
TextSentencer_T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
TextSentencer_T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
TextSentencer_T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
TextSentencer_T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
TextSentencer_T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
TextSentencer_T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue glycosmos_id image
T1 1541-1555 Glycan denotes sialyl-Lewis x https://glycosmos.org/glycans/show/G00054MO https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1541-1555 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl-Lewis x http://www.glycoepitope.jp/epitopes/EP0012

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 113-116 Lectin denotes PSA GL_000021
T2 145-148 Lectin denotes PSA GL_000021
T3 412-415 Lectin denotes PSA GL_000021
T4 506-509 Lectin denotes PSA GL_000021
T5 592-595 Lectin denotes PSA GL_000021
T6 687-690 Lectin denotes PSA GL_000021
T7 797-800 Lectin denotes PSA GL_000021
T8 838-841 Lectin denotes PSA GL_000021
T9 902-905 Lectin denotes PSA GL_000021
T10 929-932 Lectin denotes PSA GL_000021
T11 1077-1080 Lectin denotes PSA GL_000021
T12 1609-1612 Lectin denotes PSA GL_000021

Lectin-Jamboree

Id Subject Object Predicate Lexical cue
T1 1174-1180 lectin denotes lectin

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-117 Sentence denotes Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
T2 118-298 Sentence denotes Prostate-specific antigen (PSA), the tumor marker currently used for prostate cancer (PCa), is not specific enough to distinguish between PCa and benign prostate hyperplasia (BPH).
T3 299-454 Sentence denotes Glycan processing is normally perturbed in tumors, therefore we investigated whether changes in glycosylation of PSA could be useful diagnostic indicators.
T4 455-633 Sentence denotes Previously we determined that the glycosylation of PSA secreted by the tumor prostate cell line LNCaP differs significantly from that of PSA from seminal plasma (normal control).
T5 634-867 Sentence denotes We therefore undertook a detailed glycan analysis of PSA derived from sera from PCa patients and, importantly, established that the glycosylation of the PCa serum PSA was significantly different from the PSA from the LNCaP cell line.
T6 868-1040 Sentence denotes In comparison with seminal plasma PSA, the fucose content of PSA from the PCa patient serum was significantly lower and there was a decrease in alpha2,3-linked sialic acid.
T7 1041-1263 Sentence denotes Differences in the glycosylation of PSA derived from PCa patients' sera, seminal plasma, and LNCaP cells were further established by lectin detection, glycosylation immunosorbent assay, and two-dimensional electrophoresis.
T8 1264-1387 Sentence denotes We also investigated whether the impact of glycosylation changes initiated by the tumor was reflected in the serum glycome.
T9 1388-1567 Sentence denotes By comparing the glycans released from the total glycoproteins in PCa patient serum with those of normal serum we found an increase in the proportion of sialyl-Lewis x structures.
T10 1568-1788 Sentence denotes Further analysis of the glycosylation of PSA from PCa and BPH sera will be required in order to determine the utility of these glycan differences to discriminate specifically between benign and malignant prostate states.

Lectin-Jamboree-small

Id Subject Object Predicate Lexical cue glycosmos_id
T1 113-116 Lectin denotes PSA GL_002304
T2 145-148 Lectin denotes PSA GL_002304
T3 412-415 Lectin denotes PSA GL_002304
T4 506-509 Lectin denotes PSA GL_002304
T5 592-595 Lectin denotes PSA GL_002304
T6 687-690 Lectin denotes PSA GL_002304
T7 797-800 Lectin denotes PSA GL_002304
T8 838-841 Lectin denotes PSA GL_002304
T9 902-905 Lectin denotes PSA GL_002304
T10 929-932 Lectin denotes PSA GL_002304
T11 1077-1080 Lectin denotes PSA GL_002304
T12 1609-1612 Lectin denotes PSA GL_002304

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 946-953 OrganismTaxon denotes patient 9606
T2 1458-1465 OrganismTaxon denotes patient 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 31-39 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 62-70 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T3 98-112 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T4 118-126 Body_part denotes Prostate http://purl.obolibrary.org/obo/UBERON_0002367
T5 187-195 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T6 271-279 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T7 532-540 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T8 601-615 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T9 887-901 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T10 1114-1128 Body_part denotes seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530
T11 1772-1780 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367