PubMed:16046395 / 682-1022 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T6","span":{"begin":0,"end":340},"obj":"Sentence"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T3","span":{"begin":18,"end":33},"obj":"OrganismTaxon"}],"attributes":[{"id":"A3","pred":"db_id","subj":"T3","obj":"NCBItxid:10029"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-entities","denotations":[{"id":"2107","span":{"begin":18,"end":33},"obj":"OrganismTaxon"},{"id":"2108","span":{"begin":95,"end":100},"obj":"GeneOrGeneProduct"},{"id":"2109","span":{"begin":111,"end":172},"obj":"SequenceVariant"},{"id":"2110","span":{"begin":222,"end":227},"obj":"GeneOrGeneProduct"},{"id":"2111","span":{"begin":228,"end":232},"obj":"SequenceVariant"},{"id":"2112","span":{"begin":262,"end":267},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A17","pred":"db_id","subj":"2107","obj":"NCBITaxon:10029"},{"id":"A18","pred":"db_id","subj":"2108","obj":"NCBIGene:100770962"},{"id":"A19","pred":"db_id","subj":"2109","obj":"DBSNP:rs1799971"},{"id":"A20","pred":"db_id","subj":"2110","obj":"NCBIGene:100770962"},{"id":"A21","pred":"db_id","subj":"2111","obj":"DBSNP:rs1799971"},{"id":"A22","pred":"db_id","subj":"2112","obj":"NCBIGene:100770962"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T15","span":{"begin":34,"end":39},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":40,"end":45},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":51,"end":55},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":95,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":190,"end":194},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":201,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":222,"end":227},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":228,"end":232},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":251,"end":255},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":262,"end":267},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":268,"end":275},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":304,"end":312},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":317,"end":333},"obj":"GeneOrGeneProduct"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T13","span":{"begin":51,"end":55},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":95,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":190,"end":194},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":201,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":222,"end":227},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":251,"end":255},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":262,"end":267},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":268,"end":275},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":317,"end":333},"obj":"GeneOrGeneProduct"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T7","span":{"begin":95,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":222,"end":227},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":262,"end":267},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":317,"end":333},"obj":"GeneOrGeneProduct"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T4","span":{"begin":111,"end":120},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":122,"end":131},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":133,"end":141},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":147,"end":156},"obj":"ChemicalEntity"}],"attributes":[{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A5","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_16750"},{"id":"A6","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_17562"},{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17748"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T3","span":{"begin":18,"end":33},"obj":"OrganismTaxon"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T7","span":{"begin":147,"end":156},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":133,"end":141},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":122,"end":131},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":111,"end":120},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":317,"end":333},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":262,"end":267},"obj":"GeneOrGeneProduct"},{"id":"T70344","span":{"begin":222,"end":227},"obj":"GeneOrGeneProduct"},{"id":"T15751","span":{"begin":95,"end":100},"obj":"GeneOrGeneProduct"},{"id":"T95427","span":{"begin":18,"end":33},"obj":"OrganismTaxon"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17748"},{"id":"A6","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_17562"},{"id":"A5","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_16750"},{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"sentences","denotations":[{"id":"T6","span":{"begin":0,"end":340},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"NCBITAXON","denotations":[{"id":"T3","span":{"begin":18,"end":33},"obj":"OrganismTaxon"}],"attributes":[{"id":"A3","pred":"db_id","subj":"T3","obj":"10029"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T3","span":{"begin":34,"end":39},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000992"}],"text":"Transfection into Chinese hamster ovary cells of a cDNA representing only the coding region of OPRM1, carrying adenosine, guanosine, cytidine, and thymidine in position 118, resulted in 1.5-fold lower mRNA levels only for OPRM1-G118, and more than 10-fold lower OPRM1 protein levels, measured by Western blotting and receptor binding assay."}