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PubMed:1601871 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 870-873 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T3 959-976 Glycan_Motif denotes glucosyl ceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T4 1024-1041 Glycan_Motif denotes lactosyl ceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G74621DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G20420WT
T7 1058-1061 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T9 1164-1167 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T11 1352-1355 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH

sentences

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Endogenous glycosphingolipids move to the cell surface at a rate consistent with bulk flow estimates.
T2 102-323 Sentence denotes The bulk flow model of intracellular trafficking predicts that forward transport from the ER through the Golgi to the plasma membrane proceeds by default without a special signal being required (Wieland, F.T., Gleason, M.
T3 324-340 Sentence denotes L., Serafini, T.
T4 341-360 Sentence denotes A., and Rothman, J.
T5 361-389 Sentence denotes E. (1987) Cell 50, 289-300).
T6 390-571 Sentence denotes We tested a crucial prediction of this model, which is that the endogenous lipid components of the transport vesicles would reach the plasma membrane at the rapid rate of bulk flow.
T7 572-890 Sentence denotes The rate at which endogenous glycosphingolipids moved from the ER through the Golgi to the plasma membrane was determined in Chinese hamster ovary cells using metabolic labeling with tritiated palmitate and oxidation of cell surface ganglioside NeuAc alpha 2----3Gal beta 1----4Glc beta 1----4Cer (GM3) with periodate.
T8 891-1155 Sentence denotes Whereas radioactive precursor became incorporated into ceramide and glucosyl ceramide without a detectable lag, synthesis of labeled lactosyl ceramide and ganglioside GM3 did not begin until 5-6 min and 11-12 min, respectively, after addition of labeled precursor.
T9 1156-1228 Sentence denotes Labeled GM3 reached the plasma membrane 5-6 min following its synthesis.
T10 1229-1384 Sentence denotes Overall, approximately 18 min transpired from the time that the ceramide precursor was synthesized in the ER until labeled GM3 reached the plasma membrane.
T11 1385-1520 Sentence denotes These results indicate that lipid transport vesicles move rapidly to the plasma membrane at a rate consistent with bulk flow estimates.
T1 0-101 Sentence denotes Endogenous glycosphingolipids move to the cell surface at a rate consistent with bulk flow estimates.
T2 102-323 Sentence denotes The bulk flow model of intracellular trafficking predicts that forward transport from the ER through the Golgi to the plasma membrane proceeds by default without a special signal being required (Wieland, F.T., Gleason, M.
T3 324-340 Sentence denotes L., Serafini, T.
T4 341-360 Sentence denotes A., and Rothman, J.
T5 361-389 Sentence denotes E. (1987) Cell 50, 289-300).
T6 390-571 Sentence denotes We tested a crucial prediction of this model, which is that the endogenous lipid components of the transport vesicles would reach the plasma membrane at the rapid rate of bulk flow.
T7 572-890 Sentence denotes The rate at which endogenous glycosphingolipids moved from the ER through the Golgi to the plasma membrane was determined in Chinese hamster ovary cells using metabolic labeling with tritiated palmitate and oxidation of cell surface ganglioside NeuAc alpha 2----3Gal beta 1----4Glc beta 1----4Cer (GM3) with periodate.
T8 891-1155 Sentence denotes Whereas radioactive precursor became incorporated into ceramide and glucosyl ceramide without a detectable lag, synthesis of labeled lactosyl ceramide and ganglioside GM3 did not begin until 5-6 min and 11-12 min, respectively, after addition of labeled precursor.
T9 1156-1228 Sentence denotes Labeled GM3 reached the plasma membrane 5-6 min following its synthesis.
T10 1229-1384 Sentence denotes Overall, approximately 18 min transpired from the time that the ceramide precursor was synthesized in the ER until labeled GM3 reached the plasma membrane.
T11 1385-1520 Sentence denotes These results indicate that lipid transport vesicles move rapidly to the plasma membrane at a rate consistent with bulk flow estimates.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 870-873 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T2 870-873 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T3 959-976 https://glytoucan.org/Structures/Glycans/G71142DF denotes glucosyl ceramide
T4 1024-1041 https://glytoucan.org/Structures/Glycans/G20420WT denotes lactosyl ceramide
T5 1024-1041 https://glytoucan.org/Structures/Glycans/G74621DY denotes lactosyl ceramide
T6 1024-1041 https://glytoucan.org/Structures/Glycans/G84224TW denotes lactosyl ceramide
T7 1058-1061 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T8 1058-1061 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T9 1164-1167 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T10 1164-1167 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T11 1352-1355 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T12 1352-1355 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 1024-1041 http://www.glycoepitope.jp/epitopes/EP0078 denotes lactosyl ceramide

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 817-822 Glycan denotes NeuAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 870-873 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T3 1024-1041 Glycan denotes lactosyl ceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T4 1058-1061 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T5 1164-1167 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 1352-1355 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 817-822 Glycan denotes NeuAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 870-873 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T3 1024-1041 Glycan denotes lactosyl ceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T4 1058-1061 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T5 1164-1167 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 1352-1355 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1024-1041 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosyl ceramide http://www.glycoepitope.jp/epitopes/EP0078

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 697-712 Organism denotes Chinese hamster 10029

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Endogenous glycosphingolipids move to the cell surface at a rate consistent with bulk flow estimates.
T2 102-389 Sentence denotes The bulk flow model of intracellular trafficking predicts that forward transport from the ER through the Golgi to the plasma membrane proceeds by default without a special signal being required (Wieland, F.T., Gleason, M. L., Serafini, T. A., and Rothman, J. E. (1987) Cell 50, 289-300).
T3 390-571 Sentence denotes We tested a crucial prediction of this model, which is that the endogenous lipid components of the transport vesicles would reach the plasma membrane at the rapid rate of bulk flow.
T4 572-890 Sentence denotes The rate at which endogenous glycosphingolipids moved from the ER through the Golgi to the plasma membrane was determined in Chinese hamster ovary cells using metabolic labeling with tritiated palmitate and oxidation of cell surface ganglioside NeuAc alpha 2----3Gal beta 1----4Glc beta 1----4Cer (GM3) with periodate.
T5 891-1155 Sentence denotes Whereas radioactive precursor became incorporated into ceramide and glucosyl ceramide without a detectable lag, synthesis of labeled lactosyl ceramide and ganglioside GM3 did not begin until 5-6 min and 11-12 min, respectively, after addition of labeled precursor.
T6 1156-1228 Sentence denotes Labeled GM3 reached the plasma membrane 5-6 min following its synthesis.
T7 1229-1384 Sentence denotes Overall, approximately 18 min transpired from the time that the ceramide precursor was synthesized in the ER until labeled GM3 reached the plasma membrane.
T8 1385-1520 Sentence denotes These results indicate that lipid transport vesicles move rapidly to the plasma membrane at a rate consistent with bulk flow estimates.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 1024-1041 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosyl ceramide http://www.glycoepitope.jp/epitopes/EP0078

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 125-138 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T2 207-212 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T3 220-235 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T4 489-507 Body_part denotes transport vesicles http://purl.obolibrary.org/obo/GO_0030133
T5 524-539 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T6 650-655 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T7 663-678 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T8 713-718 Body_part denotes ovary http://purl.obolibrary.org/obo/UBERON_0000992
T9 1180-1195 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T10 1368-1383 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T11 1419-1437 Body_part denotes transport vesicles http://purl.obolibrary.org/obo/GO_0030133
T12 1458-1473 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 42-54 Body_part denotes cell surface FMA:67653
T2 220-235 Body_part denotes plasma membrane FMA:63841
T3 489-507 Body_part denotes transport vesicles FMA:84759
T4 524-539 Body_part denotes plasma membrane FMA:63841
T5 663-678 Body_part denotes plasma membrane FMA:63841
T6 713-718 Body_part denotes ovary FMA:7209
T7 792-804 Body_part denotes cell surface FMA:67653
T8 1180-1195 Body_part denotes plasma membrane FMA:63841
T9 1368-1383 Body_part denotes plasma membrane FMA:63841
T10 1419-1437 Body_part denotes transport vesicles FMA:84759
T11 1458-1473 Body_part denotes plasma membrane FMA:63841

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 697-712 OrganismTaxon denotes Chinese hamster 10029

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 125-138 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T2 207-212 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T3 220-235 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T4 489-507 Body_part denotes transport vesicles http://purl.obolibrary.org/obo/GO_0030133
T5 524-539 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T6 650-655 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T7 663-678 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T8 713-718 Body_part denotes ovary http://purl.obolibrary.org/obo/UBERON_0000992
T9 1180-1195 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T10 1368-1383 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T11 1419-1437 Body_part denotes transport vesicles http://purl.obolibrary.org/obo/GO_0030133
T12 1458-1473 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886