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PubMed:16018252 JSONTXT

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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-69 Sentence denotes Two novel mutations in SRY gene form Chinese sex reversal XY females.
T2 70-190 Sentence denotes The SRY gene (sex determining region on Y chromosome) acts as TDF and is required for regulating male sex determination.
T3 191-353 Sentence denotes SRY represents a transcription factor belonging to the superfamily of genes sharing the HMG-box motif (high-mobility group-box), which acts as DNA binding region.
T4 354-443 Sentence denotes Deletion and inactivating mutations of SRY are among the known causes of XY sex reversal.
T5 444-584 Sentence denotes Here, we described the screening of 10 patients who presented with 46,XY sex reversal for mutations in open reading frame (ORF) of SRY gene.
T6 585-647 Sentence denotes DNA was isolated from blood samples using standard techniques.
T7 648-752 Sentence denotes A 609 bp fragment from the central portion of the SRY gene was amplified, using primers XES-2 and XES-7.
T8 753-920 Sentence denotes The amplified PCR fragments were cloned into the pUCm-T vectors, and direct sequencing were carried out on an ABI 377-3 automated DNA sequencer to detect the mutation.
T9 921-1006 Sentence denotes PCR-restriction enzyme digestion was applied to detect the results of DNA sequencing.
T10 1007-1075 Sentence denotes In two patients,de novo mutations led to an amino acid substitution.
T11 1076-1244 Sentence denotes An A was replaced by a G in codon 38 upstream of the 5' border outside the HMG box of the SRY gene, resulting in the replacement of the amino acid glutamate by glycine.
T12 1245-1431 Sentence denotes Another heterozygous T to A transition at the nucleotide position +387 which encodes for a Tyrosine (Tyr) instead of a Term, whereas her father was proven to have the wild-type sequence.
T13 1432-1506 Sentence denotes These point mutations have been confirmed with PCR-restrict enzyme method.
T14 1507-1757 Sentence denotes As demonstrated by the Human Gene Mutation Database analysis,homology search, and review of the literature, these two mutations were not described previously and brought the total number of SRY gene nucleotide substitutions (missense/nonsense) to 45.
T15 1758-1916 Sentence denotes These findings indicated that these amino acid substitutions may be responsible for the sex reversal,not only inside the HMG-box but also outside the HMG-box.
T16 1917-2071 Sentence denotes The two novel mutations in SRY gene provided valuable information for understanding the molecular mechanism of the patient with 46,XY female sex reversal.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 809-816 OrganismTaxon denotes vectors NCBItxid:29278
T2 1104-1109 OrganismTaxon denotes codon NCBItxid:79338
T3 1530-1535 OrganismTaxon denotes Human NCBItxid:9606

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
2069 23-26 GeneOrGeneProduct denotes SRY NCBIGene:6736
2070 45-60 DiseaseOrPhenotypicFeature denotes sex reversal XY OMIM:400044
2071 74-77 GeneOrGeneProduct denotes SRY NCBIGene:6736
2072 191-194 GeneOrGeneProduct denotes SRY NCBIGene:6736
2073 393-396 GeneOrGeneProduct denotes SRY NCBIGene:6736
2074 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal OMIM:400044
2075 483-491 OrganismTaxon denotes patients NCBITaxon:9606
2076 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal OMIM:400044
2077 575-578 GeneOrGeneProduct denotes SRY NCBIGene:6736
2078 698-701 GeneOrGeneProduct denotes SRY NCBIGene:6736
2079 1014-1022 OrganismTaxon denotes patients NCBITaxon:9606
2080 1079-1112 SequenceVariant denotes A was replaced by a G in codon 38 c|SUB|A|CODON38|G
2081 1166-1169 GeneOrGeneProduct denotes SRY NCBIGene:6736
2082 1223-1243 SequenceVariant denotes glutamate by glycine p|SUB|E||G
2083 1266-1315 SequenceVariant denotes T to A transition at the nucleotide position +387 c|SUB|T|387|A
2084 1336-1368 SequenceVariant denotes Tyrosine (Tyr) instead of a Term c|SUB|Y||X
2085 1530-1535 OrganismTaxon denotes Human NCBITaxon:9606
2086 1697-1700 GeneOrGeneProduct denotes SRY NCBIGene:6736
2087 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal OMIM:400044
2088 1944-1947 GeneOrGeneProduct denotes SRY NCBIGene:6736
2089 2032-2039 OrganismTaxon denotes patient NCBITaxon:9606
2090 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal OMIM:400044

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 4-9 GeneOrGeneProduct denotes novel
T2 10-19 GeneOrGeneProduct denotes mutations
T3 84-111 GeneOrGeneProduct denotes sex determining region on Y
T4 124-128 GeneOrGeneProduct denotes acts
T5 152-166 GeneOrGeneProduct denotes for regulating
T6 167-171 GeneOrGeneProduct denotes male
T7 176-189 GeneOrGeneProduct denotes determination
T8 208-228 GeneOrGeneProduct denotes transcription factor
T9 279-286 GeneOrGeneProduct denotes HMG-box
T10 294-298 GeneOrGeneProduct denotes high
T11 326-330 GeneOrGeneProduct denotes acts
T12 334-345 GeneOrGeneProduct denotes DNA binding
T13 380-389 GeneOrGeneProduct denotes mutations
T14 534-543 GeneOrGeneProduct denotes mutations
T15 547-565 GeneOrGeneProduct denotes open reading frame
T16 567-570 GeneOrGeneProduct denotes ORF
T17 740-745 GeneOrGeneProduct denotes 2 and
T18 786-792 GeneOrGeneProduct denotes cloned
T19 802-806 GeneOrGeneProduct denotes pUCm
T20 853-856 GeneOrGeneProduct denotes out
T21 911-919 GeneOrGeneProduct denotes mutation
T22 937-943 GeneOrGeneProduct denotes enzyme
T23 1031-1040 GeneOrGeneProduct denotes mutations
T24 1051-1061 GeneOrGeneProduct denotes amino acid
T25 1132-1138 GeneOrGeneProduct denotes border
T26 1139-1146 GeneOrGeneProduct denotes outside
T27 1151-1158 GeneOrGeneProduct denotes HMG box
T28 1212-1222 GeneOrGeneProduct denotes amino acid
T29 1223-1232 GeneOrGeneProduct denotes glutamate
T30 1336-1344 GeneOrGeneProduct denotes Tyrosine
T31 1346-1349 GeneOrGeneProduct denotes Tyr
T32 1364-1368 GeneOrGeneProduct denotes Term
T33 1438-1443 GeneOrGeneProduct denotes point
T34 1444-1453 GeneOrGeneProduct denotes mutations
T35 1492-1498 GeneOrGeneProduct denotes enzyme
T36 1499-1505 GeneOrGeneProduct denotes method
T37 1541-1549 GeneOrGeneProduct denotes Mutation
T38 1568-1576 GeneOrGeneProduct denotes homology
T39 1625-1634 GeneOrGeneProduct denotes mutations
T40 1681-1686 GeneOrGeneProduct denotes total
T41 1732-1740 GeneOrGeneProduct denotes missense
T42 1764-1772 GeneOrGeneProduct denotes findings
T43 1794-1804 GeneOrGeneProduct denotes amino acid
T44 1879-1886 GeneOrGeneProduct denotes HMG-box
T45 1896-1903 GeneOrGeneProduct denotes outside
T46 1908-1915 GeneOrGeneProduct denotes HMG-box
T47 1925-1930 GeneOrGeneProduct denotes novel
T48 1931-1940 GeneOrGeneProduct denotes mutations

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 4-9 GeneOrGeneProduct denotes novel
T2 84-111 GeneOrGeneProduct denotes sex determining region on Y
T3 208-228 GeneOrGeneProduct denotes transcription factor
T4 279-286 GeneOrGeneProduct denotes HMG-box
T5 294-298 GeneOrGeneProduct denotes high
T6 334-345 GeneOrGeneProduct denotes DNA binding
T7 547-565 GeneOrGeneProduct denotes open reading frame
T8 567-570 GeneOrGeneProduct denotes ORF
T9 937-943 GeneOrGeneProduct denotes enzyme
T10 1051-1061 GeneOrGeneProduct denotes amino acid
T11 1151-1158 GeneOrGeneProduct denotes HMG box
T12 1212-1222 GeneOrGeneProduct denotes amino acid
T13 1223-1232 GeneOrGeneProduct denotes glutamate
T14 1336-1344 GeneOrGeneProduct denotes Tyrosine
T15 1346-1349 GeneOrGeneProduct denotes Tyr
T16 1364-1368 GeneOrGeneProduct denotes Term
T17 1492-1498 GeneOrGeneProduct denotes enzyme
T18 1499-1505 GeneOrGeneProduct denotes method
T19 1794-1804 GeneOrGeneProduct denotes amino acid
T20 1879-1886 GeneOrGeneProduct denotes HMG-box
T21 1908-1915 GeneOrGeneProduct denotes HMG-box
T22 1925-1930 GeneOrGeneProduct denotes novel

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 58-68 DiseaseOrPhenotypicFeature denotes XY females C536769
T2 2048-2057 DiseaseOrPhenotypicFeature denotes XY female C536769

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 84-111 GeneOrGeneProduct denotes sex determining region on Y
T2 208-228 GeneOrGeneProduct denotes transcription factor
T3 294-317 GeneOrGeneProduct denotes high-mobility group-box
T4 1223-1232 GeneOrGeneProduct denotes glutamate

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal 0010765
T2 2048-2057 DiseaseOrPhenotypicFeature denotes XY female 0020040

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 45-57 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T2 58-68 DiseaseOrPhenotypicFeature denotes XY females C536769
T3 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal DISEASE
T4 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal DISEASE
T5 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T6 2048-2057 DiseaseOrPhenotypicFeature denotes XY female C536769
T7 2058-2070 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 45-57 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T2 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal DISEASE
T3 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal DISEASE
T4 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T5 2045-2057 DiseaseOrPhenotypicFeature denotes 46,XY female C536769
T6 2058-2070 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 132-135 ChemicalEntity denotes TDF http://purl.obolibrary.org/obo/CHEBI_63718
T2 1223-1232 ChemicalEntity denotes glutamate http://purl.obolibrary.org/obo/CHEBI_29987|http://purl.obolibrary.org/obo/CHEBI_14321
T4 1236-1243 ChemicalEntity denotes glycine http://purl.obolibrary.org/obo/CHEBI_57305|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_15428
T7 1336-1344 ChemicalEntity denotes Tyrosine http://purl.obolibrary.org/obo/CHEBI_18186|http://purl.obolibrary.org/obo/CHEBI_17895
T9 1346-1349 ChemicalEntity denotes Tyr http://purl.obolibrary.org/obo/CHEBI_46858|http://purl.obolibrary.org/obo/CHEBI_18186|http://purl.obolibrary.org/obo/CHEBI_17895

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 483-491 OrganismTaxon denotes patients
T2 1014-1022 OrganismTaxon denotes patients
T3 1530-1535 OrganismTaxon denotes Human
T4 2032-2039 OrganismTaxon denotes patient

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T9 1346-1349 ChemicalEntity denotes Tyr http://purl.obolibrary.org/obo/CHEBI_17895|http://purl.obolibrary.org/obo/CHEBI_18186|http://purl.obolibrary.org/obo/CHEBI_46858
T7 1336-1344 ChemicalEntity denotes Tyrosine http://purl.obolibrary.org/obo/CHEBI_17895|http://purl.obolibrary.org/obo/CHEBI_18186
T4 1236-1243 ChemicalEntity denotes glycine http://purl.obolibrary.org/obo/CHEBI_15428|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_57305
T2 1223-1232 ChemicalEntity denotes glutamate http://purl.obolibrary.org/obo/CHEBI_14321|http://purl.obolibrary.org/obo/CHEBI_29987
T1 132-135 ChemicalEntity denotes TDF http://purl.obolibrary.org/obo/CHEBI_63718
T96524 1223-1232 GeneOrGeneProduct denotes glutamate
T3 294-317 GeneOrGeneProduct denotes high-mobility group-box
T62972 208-228 GeneOrGeneProduct denotes transcription factor
T71784 84-111 GeneOrGeneProduct denotes sex determining region on Y
T6 2058-2070 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T5 2045-2057 DiseaseOrPhenotypicFeature denotes 46,XY female C536769
T75887 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T72282 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal DISEASE
T51551 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal DISEASE
T97328 45-57 DiseaseOrPhenotypicFeature denotes sex reversal DISEASE
T27634 2032-2039 OrganismTaxon denotes patient
T28486 1530-1535 OrganismTaxon denotes Human
T97862 1014-1022 OrganismTaxon denotes patients
T69269 483-491 OrganismTaxon denotes patients

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 430-442 HP_0012245 denotes sex reversal
T2 517-529 HP_0012245 denotes sex reversal
T3 1846-1858 HP_0012245 denotes sex reversal
T4 2058-2070 HP_0012245 denotes sex reversal

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1944-1947 gene:6736 denotes SRY
T1 2045-2057 disease:C0432470 denotes 46,XY female
R1 T0 T1 associated_with SRY,"46,XY female"

biored-valid

Id Subject Object Predicate Lexical cue
T1 23-26 GeneOrGeneProduct denotes SRY
T2 45-60 DiseaseOrPhenotypicFeature denotes sex reversal XY
T3 74-77 GeneOrGeneProduct denotes SRY
T4 191-194 GeneOrGeneProduct denotes SRY
T5 393-396 GeneOrGeneProduct denotes SRY
T6 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T7 483-491 OrganismTaxon denotes patients
T8 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T9 575-578 GeneOrGeneProduct denotes SRY
T10 698-701 GeneOrGeneProduct denotes SRY
T11 1014-1022 OrganismTaxon denotes patients
T12 1079-1112 SequenceVariant denotes A was replaced by a G in codon 38
T13 1166-1169 GeneOrGeneProduct denotes SRY
T14 1223-1243 SequenceVariant denotes glutamate by glycine
T15 1266-1315 SequenceVariant denotes T to A transition at the nucleotide position +387
T16 1336-1368 SequenceVariant denotes Tyrosine (Tyr) instead of a Term
T17 1530-1535 OrganismTaxon denotes Human
T18 1697-1700 GeneOrGeneProduct denotes SRY
T19 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T20 1944-1947 GeneOrGeneProduct denotes SRY
T21 2032-2039 OrganismTaxon denotes patient
T22 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-deepseek-nr-ng

Id Subject Object Predicate Lexical cue
T1 23-26 GeneOrGeneProduct denotes SRY
T2 58-68 DiseaseOrPhenotypicFeature denotes XY females
T3 132-135 GeneOrGeneProduct denotes TDF
T4 191-194 GeneOrGeneProduct denotes SRY
T5 334-337 ChemicalEntity denotes DNA
T6 393-396 GeneOrGeneProduct denotes SRY
T7 427-429 DiseaseOrPhenotypicFeature denotes XY
T8 430-442 DiseaseOrPhenotypicFeature denotes sex reversal
T9 514-516 DiseaseOrPhenotypicFeature denotes XY
T10 575-578 GeneOrGeneProduct denotes SRY
T11 585-588 ChemicalEntity denotes DNA
T12 698-701 GeneOrGeneProduct denotes SRY
T13 767-770 ChemicalEntity denotes PCR
T14 802-808 ChemicalEntity denotes pUCm-T
T15 863-866 ChemicalEntity denotes ABI
T16 867-870 ChemicalEntity denotes 377
T17 870-872 ChemicalEntity denotes -3
T18 921-924 ChemicalEntity denotes PCR
T19 925-943 ChemicalEntity denotes restriction enzyme
T20 1166-1169 GeneOrGeneProduct denotes SRY
T21 1336-1339 ChemicalEntity denotes Tyr
T22 1364-1368 ChemicalEntity denotes Term
T23 1483-1498 ChemicalEntity denotes restrict enzyme
T24 2051-2070 DiseaseOrPhenotypicFeature denotes female sex reversal

biored-valid-deepseek-nr-g

Id Subject Object Predicate Lexical cue
T1 23-26 GeneOrGeneProduct denotes SRY
T2 37-57 DiseaseOrPhenotypicFeature denotes Chinese sex reversal
T3 58-68 DiseaseOrPhenotypicFeature denotes XY females
T4 74-77 GeneOrGeneProduct denotes SRY
T5 84-122 GeneOrGeneProduct denotes sex determining region on Y chromosome
T6 132-135 GeneOrGeneProduct denotes TDF
T7 191-194 GeneOrGeneProduct denotes SRY
T8 279-286 GeneOrGeneProduct denotes HMG-box
T9 294-317 GeneOrGeneProduct denotes high-mobility group-box
T10 393-396 GeneOrGeneProduct denotes SRY
T11 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T12 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T13 575-578 GeneOrGeneProduct denotes SRY
T14 698-701 GeneOrGeneProduct denotes SRY
T15 1151-1158 GeneOrGeneProduct denotes HMG box
T16 1336-1339 ChemicalEntity denotes Tyr
T17 1364-1368 SequenceVariant denotes Term
T18 1530-1535 OrganismTaxon denotes Human
T19 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-deepseek-r-ng

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-68 DiseaseOrPhenotypicFeature denotes sex reversal XY females
T3 74-77 GeneOrGeneProduct denotes SRY
T4 132-135 GeneOrGeneProduct denotes TDF
T5 334-337 ChemicalEntity denotes DNA
T6 380-389 SequenceVariant denotes mutations
T7 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T8 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T9 534-543 SequenceVariant denotes mutations
T10 575-583 GeneOrGeneProduct denotes SRY gene
T11 698-706 GeneOrGeneProduct denotes SRY gene
T12 1079-1100 SequenceVariant denotes A was replaced by a G
T13 1223-1232 ChemicalEntity denotes glutamate
T14 1236-1243 ChemicalEntity denotes glycine
T15 1253-1283 SequenceVariant denotes heterozygous T to A transition
T16 1336-1344 ChemicalEntity denotes Tyrosine
T17 1438-1453 SequenceVariant denotes point mutations
T18 1530-1535 OrganismTaxon denotes Human
T19 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-deepseek-r-g

Id Subject Object Predicate Lexical cue
T1 4-19 SequenceVariant denotes novel mutations
T2 23-31 GeneOrGeneProduct denotes SRY gene
T3 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T4 74-82 GeneOrGeneProduct denotes SRY gene
T5 132-135 GeneOrGeneProduct denotes TDF
T6 191-194 GeneOrGeneProduct denotes SRY
T7 393-396 GeneOrGeneProduct denotes SRY
T8 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T9 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T10 575-583 GeneOrGeneProduct denotes SRY gene
T11 698-706 GeneOrGeneProduct denotes SRY gene
T12 1023-1040 SequenceVariant denotes de novo mutations
T13 1051-1074 SequenceVariant denotes amino acid substitution
T14 1076-1112 SequenceVariant denotes An A was replaced by a G in codon 38
T15 1166-1174 GeneOrGeneProduct denotes SRY gene
T16 1266-1315 SequenceVariant denotes T to A transition at the nucleotide position +387
T17 1438-1453 SequenceVariant denotes point mutations
T18 1697-1705 GeneOrGeneProduct denotes SRY gene
T19 1706-1750 SequenceVariant denotes nucleotide substitutions (missense/nonsense)
T20 1794-1818 SequenceVariant denotes amino acid substitutions
T21 1944-1952 GeneOrGeneProduct denotes SRY gene
T22 2051-2070 DiseaseOrPhenotypicFeature denotes female sex reversal

biored-valid-gemini-nr-ng

Id Subject Object Predicate Lexical cue
T1 23-26 GeneOrGeneProduct denotes SRY
T2 45-60 DiseaseOrPhenotypicFeature denotes sex reversal XY
T3 74-77 GeneOrGeneProduct denotes SRY
T4 132-135 GeneOrGeneProduct denotes TDF
T5 167-189 DiseaseOrPhenotypicFeature denotes male sex determination
T6 191-194 GeneOrGeneProduct denotes SRY
T7 279-286 GeneOrGeneProduct denotes HMG-box
T8 367-389 SequenceVariant denotes inactivating mutations
T9 393-396 GeneOrGeneProduct denotes SRY
T10 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T11 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T12 575-578 GeneOrGeneProduct denotes SRY
T13 585-588 ChemicalEntity denotes DNA
T14 698-701 GeneOrGeneProduct denotes SRY
T15 1023-1040 SequenceVariant denotes de novo mutations
T16 1051-1074 SequenceVariant denotes amino acid substitution
T17 1151-1158 GeneOrGeneProduct denotes HMG box
T18 1166-1169 GeneOrGeneProduct denotes SRY
T19 1223-1232 ChemicalEntity denotes glutamate
T20 1236-1243 ChemicalEntity denotes glycine
T21 1253-1283 SequenceVariant denotes heterozygous T to A transition
T22 1336-1344 ChemicalEntity denotes Tyrosine
T23 1364-1368 SequenceVariant denotes Term
T24 1438-1453 SequenceVariant denotes point mutations
T25 1625-1634 SequenceVariant denotes mutations
T26 1697-1700 GeneOrGeneProduct denotes SRY
T27 1706-1730 SequenceVariant denotes nucleotide substitutions
T28 1732-1740 SequenceVariant denotes missense
T29 1741-1749 SequenceVariant denotes nonsense
T30 1794-1818 SequenceVariant denotes amino acid substitutions
T31 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T32 1879-1886 GeneOrGeneProduct denotes HMG-box
T33 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gemini-r-ng

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 37-44 OrganismTaxon denotes Chinese
T3 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T4 58-68 DiseaseOrPhenotypicFeature denotes XY females
T5 74-82 GeneOrGeneProduct denotes SRY gene
T6 132-135 GeneOrGeneProduct denotes TDF
T7 191-194 GeneOrGeneProduct denotes SRY
T8 279-286 GeneOrGeneProduct denotes HMG-box
T9 294-317 GeneOrGeneProduct denotes high-mobility group-box
T10 334-337 ChemicalEntity denotes DNA
T11 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T12 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T13 575-583 GeneOrGeneProduct denotes SRY gene
T14 585-588 ChemicalEntity denotes DNA
T15 648-649 ChemicalEntity denotes A
T16 698-706 GeneOrGeneProduct denotes SRY gene
T17 736-741 GeneOrGeneProduct denotes XES-2
T18 746-751 GeneOrGeneProduct denotes XES-7
T19 802-816 GeneOrGeneProduct denotes pUCm-T vectors
T20 1051-1074 SequenceVariant denotes amino acid substitution
T21 1099-1100 ChemicalEntity denotes G
T22 1151-1158 GeneOrGeneProduct denotes HMG box
T23 1166-1174 GeneOrGeneProduct denotes SRY gene
T24 1223-1232 ChemicalEntity denotes glutamate
T25 1236-1243 ChemicalEntity denotes glycine
T26 1253-1315 SequenceVariant denotes heterozygous T to A transition at the nucleotide position +387
T27 1336-1344 ChemicalEntity denotes Tyrosine
T28 1438-1453 SequenceVariant denotes point mutations
T29 1732-1740 SequenceVariant denotes missense
T30 1741-1749 SequenceVariant denotes nonsense
T31 1794-1818 SequenceVariant denotes amino acid substitutions
T32 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T33 1879-1886 GeneOrGeneProduct denotes HMG-box
T34 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gemini-r-g

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 132-135 GeneOrGeneProduct denotes TDF
T4 191-194 GeneOrGeneProduct denotes SRY
T5 279-286 GeneOrGeneProduct denotes HMG-box
T6 294-317 GeneOrGeneProduct denotes high-mobility group-box
T7 354-362 SequenceVariant denotes Deletion
T8 393-396 GeneOrGeneProduct denotes SRY
T9 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T10 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T11 575-583 GeneOrGeneProduct denotes SRY gene
T12 698-706 GeneOrGeneProduct denotes SRY gene
T13 736-741 ChemicalEntity denotes XES-2
T14 746-751 ChemicalEntity denotes XES-7
T15 802-816 ChemicalEntity denotes pUCm-T vectors
T16 1023-1040 SequenceVariant denotes de novo mutations
T17 1051-1074 SequenceVariant denotes amino acid substitution
T18 1079-1100 SequenceVariant denotes A was replaced by a G
T19 1151-1158 GeneOrGeneProduct denotes HMG box
T20 1166-1174 GeneOrGeneProduct denotes SRY gene
T21 1253-1283 SequenceVariant denotes heterozygous T to A transition
T22 1438-1453 SequenceVariant denotes point mutations
T23 1530-1535 OrganismTaxon denotes Human
T24 1706-1750 SequenceVariant denotes nucleotide substitutions (missense/nonsense)
T25 1794-1818 SequenceVariant denotes amino acid substitutions
T26 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T27 1879-1886 GeneOrGeneProduct denotes HMG-box
T28 1944-1952 GeneOrGeneProduct denotes SRY gene
T29 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gpt-nr-ng

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 74-82 GeneOrGeneProduct denotes SRY gene
T4 132-135 GeneOrGeneProduct denotes TDF
T5 191-194 GeneOrGeneProduct denotes SRY
T6 334-337 ChemicalEntity denotes DNA
T7 393-396 GeneOrGeneProduct denotes SRY
T8 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T9 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T10 575-583 GeneOrGeneProduct denotes SRY gene
T11 585-588 ChemicalEntity denotes DNA
T12 698-706 GeneOrGeneProduct denotes SRY gene
T13 883-886 ChemicalEntity denotes DNA
T14 991-994 ChemicalEntity denotes DNA
T15 1023-1040 SequenceVariant denotes de novo mutations
T16 1076-1100 SequenceVariant denotes An A was replaced by a G
T17 1166-1174 GeneOrGeneProduct denotes SRY gene
T18 1223-1232 ChemicalEntity denotes glutamate
T19 1236-1243 ChemicalEntity denotes glycine
T20 1266-1283 SequenceVariant denotes T to A transition
T21 1336-1350 ChemicalEntity denotes Tyrosine (Tyr)
T22 1438-1453 SequenceVariant denotes point mutations
T23 1530-1535 OrganismTaxon denotes Human
T24 1697-1705 GeneOrGeneProduct denotes SRY gene
T25 1706-1750 SequenceVariant denotes nucleotide substitutions (missense/nonsense)
T26 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T27 1944-1952 GeneOrGeneProduct denotes SRY gene
T28 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gpt-nr-g

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 74-82 GeneOrGeneProduct denotes SRY gene
T4 84-122 GeneOrGeneProduct denotes sex determining region on Y chromosome
T5 132-135 GeneOrGeneProduct denotes TDF
T6 191-194 GeneOrGeneProduct denotes SRY
T7 393-396 GeneOrGeneProduct denotes SRY
T8 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T9 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T10 575-583 GeneOrGeneProduct denotes SRY gene
T11 698-706 GeneOrGeneProduct denotes SRY gene
T12 1076-1100 SequenceVariant denotes An A was replaced by a G
T13 1166-1174 GeneOrGeneProduct denotes SRY gene
T14 1223-1243 SequenceVariant denotes glutamate by glycine
T15 1266-1283 SequenceVariant denotes T to A transition
T16 1336-1368 SequenceVariant denotes Tyrosine (Tyr) instead of a Term
T17 1697-1705 GeneOrGeneProduct denotes SRY gene
T18 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T19 1944-1952 GeneOrGeneProduct denotes SRY gene
T20 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gpt-r-ng

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 74-82 GeneOrGeneProduct denotes SRY gene
T4 132-135 GeneOrGeneProduct denotes TDF
T5 191-194 GeneOrGeneProduct denotes SRY
T6 334-337 ChemicalEntity denotes DNA
T7 393-396 GeneOrGeneProduct denotes SRY
T8 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T9 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T10 575-583 GeneOrGeneProduct denotes SRY gene
T11 585-588 ChemicalEntity denotes DNA
T12 698-706 GeneOrGeneProduct denotes SRY gene
T13 883-886 ChemicalEntity denotes DNA
T14 991-994 ChemicalEntity denotes DNA
T15 1076-1100 SequenceVariant denotes An A was replaced by a G
T16 1166-1174 GeneOrGeneProduct denotes SRY gene
T17 1223-1232 ChemicalEntity denotes glutamate
T18 1236-1243 ChemicalEntity denotes glycine
T19 1253-1315 SequenceVariant denotes heterozygous T to A transition at the nucleotide position +387
T20 1336-1344 ChemicalEntity denotes Tyrosine
T21 1530-1535 OrganismTaxon denotes Human
T22 1697-1705 GeneOrGeneProduct denotes SRY gene
T23 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T24 1944-1952 GeneOrGeneProduct denotes SRY gene
T25 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gpt-r-g

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 74-82 GeneOrGeneProduct denotes SRY gene
T4 84-122 GeneOrGeneProduct denotes sex determining region on Y chromosome
T5 132-135 GeneOrGeneProduct denotes TDF
T6 191-194 GeneOrGeneProduct denotes SRY
T7 354-362 SequenceVariant denotes Deletion
T8 367-389 SequenceVariant denotes inactivating mutations
T9 393-396 GeneOrGeneProduct denotes SRY
T10 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T11 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T12 575-583 GeneOrGeneProduct denotes SRY gene
T13 698-706 GeneOrGeneProduct denotes SRY gene
T14 1051-1074 SequenceVariant denotes amino acid substitution
T15 1076-1100 SequenceVariant denotes An A was replaced by a G
T16 1166-1174 GeneOrGeneProduct denotes SRY gene
T17 1193-1243 SequenceVariant denotes replacement of the amino acid glutamate by glycine
T18 1253-1283 SequenceVariant denotes heterozygous T to A transition
T19 1336-1368 SequenceVariant denotes Tyrosine (Tyr) instead of a Term
T20 1438-1453 SequenceVariant denotes point mutations
T21 1697-1705 GeneOrGeneProduct denotes SRY gene
T22 1706-1730 SequenceVariant denotes nucleotide substitutions
T23 1732-1749 SequenceVariant denotes missense/nonsense
T24 1794-1818 SequenceVariant denotes amino acid substitutions
T25 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T26 1944-1952 GeneOrGeneProduct denotes SRY gene
T27 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gemini-nr-g

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-68 DiseaseOrPhenotypicFeature denotes sex reversal XY females
T3 167-189 DiseaseOrPhenotypicFeature denotes male sex determination
T4 191-194 GeneOrGeneProduct denotes SRY
T5 279-286 GeneOrGeneProduct denotes HMG-box
T6 334-337 ChemicalEntity denotes DNA
T7 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T8 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T9 575-583 GeneOrGeneProduct denotes SRY gene
T10 698-706 GeneOrGeneProduct denotes SRY gene
T11 767-770 ChemicalEntity denotes PCR
T12 802-816 ChemicalEntity denotes pUCm-T vectors
T13 863-864 ChemicalEntity denotes A
T14 883-886 ChemicalEntity denotes DNA
T15 921-924 ChemicalEntity denotes PCR
T16 1051-1074 SequenceVariant denotes amino acid substitution
T17 1099-1100 ChemicalEntity denotes G
T18 1151-1158 GeneOrGeneProduct denotes HMG box
T19 1223-1232 ChemicalEntity denotes glutamate
T20 1236-1243 ChemicalEntity denotes glycine
T21 1266-1283 SequenceVariant denotes T to A transition
T22 1336-1344 ChemicalEntity denotes Tyrosine
T23 1438-1453 SequenceVariant denotes point mutations
T24 1697-1750 SequenceVariant denotes SRY gene nucleotide substitutions (missense/nonsense)
T25 1794-1818 SequenceVariant denotes amino acid substitutions
T26 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T27 1879-1886 GeneOrGeneProduct denotes HMG-box
T28 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gpt-r-m

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 45-57 DiseaseOrPhenotypicFeature denotes sex reversal
T3 74-82 GeneOrGeneProduct denotes SRY gene
T4 84-122 GeneOrGeneProduct denotes sex determining region on Y chromosome
T5 132-135 GeneOrGeneProduct denotes TDF
T6 191-194 GeneOrGeneProduct denotes SRY
T7 334-337 ChemicalEntity denotes DNA
T8 354-362 SequenceVariant denotes Deletion
T9 367-389 SequenceVariant denotes inactivating mutations
T10 393-396 GeneOrGeneProduct denotes SRY
T11 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T12 483-491 OrganismTaxon denotes patients
T13 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T14 575-583 GeneOrGeneProduct denotes SRY gene
T15 585-588 ChemicalEntity denotes DNA
T16 698-706 GeneOrGeneProduct denotes SRY gene
T17 883-886 ChemicalEntity denotes DNA
T18 991-994 ChemicalEntity denotes DNA
T19 1014-1022 OrganismTaxon denotes patients
T20 1023-1040 SequenceVariant denotes de novo mutations
T21 1051-1074 SequenceVariant denotes amino acid substitution
T22 1079-1100 SequenceVariant denotes A was replaced by a G
T23 1166-1174 GeneOrGeneProduct denotes SRY gene
T24 1266-1283 SequenceVariant denotes T to A transition
T25 1438-1453 SequenceVariant denotes point mutations
T26 1697-1705 GeneOrGeneProduct denotes SRY gene
T27 1706-1730 SequenceVariant denotes nucleotide substitutions
T28 1732-1749 SequenceVariant denotes missense/nonsense
T29 1794-1818 SequenceVariant denotes amino acid substitutions
T30 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T31 1944-1952 GeneOrGeneProduct denotes SRY gene
T32 2032-2039 OrganismTaxon denotes patient
T33 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-gemini-r-m

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 37-44 OrganismTaxon denotes Chinese
T3 45-68 DiseaseOrPhenotypicFeature denotes sex reversal XY females
T4 74-123 GeneOrGeneProduct denotes SRY gene (sex determining region on Y chromosome)
T5 132-135 GeneOrGeneProduct denotes TDF
T6 191-194 GeneOrGeneProduct denotes SRY
T7 279-318 GeneOrGeneProduct denotes HMG-box motif (high-mobility group-box)
T8 334-337 ChemicalEntity denotes DNA
T9 393-396 GeneOrGeneProduct denotes SRY
T10 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T11 483-491 OrganismTaxon denotes patients
T12 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T13 575-583 GeneOrGeneProduct denotes SRY gene
T14 585-588 ChemicalEntity denotes DNA
T15 736-741 ChemicalEntity denotes XES-2
T16 746-751 ChemicalEntity denotes XES-7
T17 802-816 ChemicalEntity denotes pUCm-T vectors
T18 883-886 ChemicalEntity denotes DNA
T19 1014-1022 OrganismTaxon denotes patients
T20 1079-1112 SequenceVariant denotes A was replaced by a G in codon 38
T21 1151-1158 GeneOrGeneProduct denotes HMG box
T22 1166-1174 GeneOrGeneProduct denotes SRY gene
T23 1253-1315 SequenceVariant denotes heterozygous T to A transition at the nucleotide position +387
T24 1382-1388 OrganismTaxon denotes father
T25 1697-1705 GeneOrGeneProduct denotes SRY gene
T26 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T27 1879-1886 GeneOrGeneProduct denotes HMG-box
T28 2032-2039 OrganismTaxon denotes patient
T29 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal

biored-valid-deepseek-r-m

Id Subject Object Predicate Lexical cue
T1 23-31 GeneOrGeneProduct denotes SRY gene
T2 74-77 GeneOrGeneProduct denotes SRY
T3 132-135 GeneOrGeneProduct denotes TDF
T4 191-194 GeneOrGeneProduct denotes SRY
T5 279-292 GeneOrGeneProduct denotes HMG-box motif
T6 427-442 DiseaseOrPhenotypicFeature denotes XY sex reversal
T7 511-529 DiseaseOrPhenotypicFeature denotes 46,XY sex reversal
T8 575-583 GeneOrGeneProduct denotes SRY gene
T9 698-706 GeneOrGeneProduct denotes SRY gene
T10 1023-1040 SequenceVariant denotes de novo mutations
T11 1051-1074 SequenceVariant denotes amino acid substitution
T12 1151-1158 GeneOrGeneProduct denotes HMG box
T13 1166-1174 GeneOrGeneProduct denotes SRY gene
T14 1266-1283 SequenceVariant denotes T to A transition
T15 1438-1453 SequenceVariant denotes point mutations
T16 1706-1730 SequenceVariant denotes nucleotide substitutions
T17 1846-1858 DiseaseOrPhenotypicFeature denotes sex reversal
T18 1879-1886 GeneOrGeneProduct denotes HMG-box
T19 2045-2070 DiseaseOrPhenotypicFeature denotes 46,XY female sex reversal