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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-92 Sentence denotes Nicotine antagonizes caffeine- but not pentylenetetrazole-induced anxiogenic effect in mice.
T2 93-103 Sentence denotes RATIONALE:
T3 104-181 Sentence denotes Nicotine and caffeine are widely consumed licit psychoactive drugs worldwide.
T4 182-256 Sentence denotes Epidemiological studies showed that they were generally used concurrently.
T5 257-427 Sentence denotes Although some studies in experimental animals indicate clear pharmacological interactions between them, no studies have shown a specific interaction on anxiety responses.
T6 428-439 Sentence denotes OBJECTIVES:
T7 440-583 Sentence denotes The present study investigates the effects of nicotine on anxiety induced by caffeine and another anxiogenic drug, pentylenetetrazole, in mice.
T8 584-671 Sentence denotes The elevated plus-maze (EPM) test was used to evaluate the effects of drugs on anxiety.
T9 672-680 Sentence denotes METHODS:
T10 681-869 Sentence denotes Adult male Swiss Webster mice (25-32 g) were given nicotine (0.05-0.25 mg/kg s.c.) or saline 10 min before caffeine (70 mg/kg i.p.) or pentylenetetrazole (15 and 30 mg/kg i.p.) injections.
T11 870-984 Sentence denotes After 15 min, mice were evaluated for their open- and closed-arm time and entries on the EPM for a 10-min session.
T12 985-1094 Sentence denotes Locomotor activity was recorded for individual groups by using the same treatment protocol with the EPM test.
T13 1095-1103 Sentence denotes RESULTS:
T14 1104-1338 Sentence denotes Nicotine (0.05-0.25 mg/kg) itself did not produce any significant effect in the EPM test, whereas caffeine (70 mg/kg) and pentylenetetrazole (30 mg/kg) produced an anxiogenic effect, apparent with decreases in open-arm time and entry.
T15 1339-1439 Sentence denotes Nicotine (0.25 mg/kg) pretreatment blocked the caffeine- but not pentylenetetrazole-induced anxiety.
T16 1440-1540 Sentence denotes Administration of each drug and their combinations did not produce any effect on locomotor activity.
T17 1541-1553 Sentence denotes CONCLUSIONS:
T18 1554-1712 Sentence denotes Our results suggest that the antagonistic effect of nicotine on caffeine-induced anxiety is specific to caffeine, instead of a non-specific anxiolytic effect.
T19 1713-1803 Sentence denotes Thus, it may extend the current findings on the interaction between nicotine and caffeine.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 87-91 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T3 578-582 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T5 706-710 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T7 884-888 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
1992 0-8 ChemicalEntity denotes Nicotine MESH:D009538
1993 21-29 ChemicalEntity denotes caffeine MESH:D002110
1994 39-57 ChemicalEntity denotes pentylenetetrazole MESH:D010433
1995 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect MESH:D001008
1996 87-91 OrganismTaxon denotes mice NCBITaxon:10090
1997 104-112 ChemicalEntity denotes Nicotine MESH:D009538
1998 117-125 ChemicalEntity denotes caffeine MESH:D002110
1999 152-170 ChemicalEntity denotes psychoactive drugs MESH:D011619
2000 409-416 DiseaseOrPhenotypicFeature denotes anxiety MESH:D001008
2001 486-494 ChemicalEntity denotes nicotine MESH:D009538
2002 498-505 DiseaseOrPhenotypicFeature denotes anxiety MESH:D001008
2003 517-525 ChemicalEntity denotes caffeine MESH:D002110
2004 538-553 ChemicalEntity denotes anxiogenic drug MESH:D014151
2005 555-573 ChemicalEntity denotes pentylenetetrazole MESH:D010433
2006 578-582 OrganismTaxon denotes mice NCBITaxon:10090
2007 663-670 DiseaseOrPhenotypicFeature denotes anxiety MESH:D001008
2008 706-710 OrganismTaxon denotes mice NCBITaxon:10090
2009 732-740 ChemicalEntity denotes nicotine MESH:D009538
2010 788-796 ChemicalEntity denotes caffeine MESH:D002110
2011 816-834 ChemicalEntity denotes pentylenetetrazole MESH:D010433
2012 884-888 OrganismTaxon denotes mice NCBITaxon:10090
2013 1104-1112 ChemicalEntity denotes Nicotine MESH:D009538
2014 1202-1210 ChemicalEntity denotes caffeine MESH:D002110
2015 1226-1244 ChemicalEntity denotes pentylenetetrazole MESH:D010433
2016 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect MESH:D001008
2017 1339-1347 ChemicalEntity denotes Nicotine MESH:D009538
2018 1386-1394 ChemicalEntity denotes caffeine MESH:D002110
2019 1404-1422 ChemicalEntity denotes pentylenetetrazole MESH:D010433
2020 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety MESH:D001008
2021 1606-1614 ChemicalEntity denotes nicotine MESH:D009538
2022 1618-1626 ChemicalEntity denotes caffeine MESH:D002110
2023 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety MESH:D001008
2024 1658-1666 ChemicalEntity denotes caffeine MESH:D002110
2025 1781-1789 ChemicalEntity denotes nicotine MESH:D009538
2026 1794-1802 ChemicalEntity denotes caffeine MESH:D002110

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 409-416 DiseaseOrPhenotypicFeature denotes anxiety 0011918
T2 498-505 DiseaseOrPhenotypicFeature denotes anxiety 0011918
T3 663-670 DiseaseOrPhenotypicFeature denotes anxiety 0011918
T4 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety 0011918
T5 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety 0011918

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 58-65 GeneOrGeneProduct denotes induced
T2 87-91 GeneOrGeneProduct denotes mice
T3 355-359 GeneOrGeneProduct denotes them
T4 409-416 GeneOrGeneProduct denotes anxiety
T5 498-505 GeneOrGeneProduct denotes anxiety
T6 506-513 GeneOrGeneProduct denotes induced
T7 578-582 GeneOrGeneProduct denotes mice
T8 602-606 GeneOrGeneProduct denotes maze
T9 613-617 GeneOrGeneProduct denotes test
T10 663-670 GeneOrGeneProduct denotes anxiety
T11 672-679 GeneOrGeneProduct denotes METHODS
T12 687-691 GeneOrGeneProduct denotes male
T13 706-710 GeneOrGeneProduct denotes mice
T14 752-754 GeneOrGeneProduct denotes mg
T15 801-803 GeneOrGeneProduct denotes mg
T16 846-848 GeneOrGeneProduct denotes mg
T17 884-888 GeneOrGeneProduct denotes mice
T18 914-918 GeneOrGeneProduct denotes open
T19 935-939 GeneOrGeneProduct denotes time
T20 967-971 GeneOrGeneProduct denotes a 10
T21 995-1003 GeneOrGeneProduct denotes activity
T22 1089-1093 GeneOrGeneProduct denotes test
T23 1124-1126 GeneOrGeneProduct denotes mg
T24 1188-1192 GeneOrGeneProduct denotes test
T25 1215-1217 GeneOrGeneProduct denotes mg
T26 1249-1251 GeneOrGeneProduct denotes mg
T27 1314-1318 GeneOrGeneProduct denotes open
T28 1323-1327 GeneOrGeneProduct denotes time
T29 1354-1356 GeneOrGeneProduct denotes mg
T30 1374-1381 GeneOrGeneProduct denotes blocked
T31 1423-1430 GeneOrGeneProduct denotes induced
T32 1431-1438 GeneOrGeneProduct denotes anxiety
T33 1531-1539 GeneOrGeneProduct denotes activity
T34 1583-1595 GeneOrGeneProduct denotes antagonistic
T35 1627-1634 GeneOrGeneProduct denotes induced
T36 1635-1642 GeneOrGeneProduct denotes anxiety
T37 1681-1693 GeneOrGeneProduct denotes non-specific
T38 1726-1732 GeneOrGeneProduct denotes extend
T39 1745-1753 GeneOrGeneProduct denotes findings

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 409-416 GeneOrGeneProduct denotes anxiety
T2 498-505 GeneOrGeneProduct denotes anxiety
T3 663-670 GeneOrGeneProduct denotes anxiety
T4 1374-1381 GeneOrGeneProduct denotes blocked
T5 1431-1438 GeneOrGeneProduct denotes anxiety
T6 1635-1642 GeneOrGeneProduct denotes anxiety
T7 1681-1693 GeneOrGeneProduct denotes non-specific
T8 1726-1732 GeneOrGeneProduct denotes extend

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 409-416 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T2 498-505 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T3 663-670 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T4 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T5 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety DISEASE

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 1681-1693 GeneOrGeneProduct denotes non-specific

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 409-416 DiseaseOrPhenotypicFeature denotes anxiety 0011918|0005618
T3 498-505 DiseaseOrPhenotypicFeature denotes anxiety 0011918|0005618
T5 663-670 DiseaseOrPhenotypicFeature denotes anxiety 0011918|0005618
T7 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety 0011918|0005618
T9 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety 0011918|0005618

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T2 409-416 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T3 498-505 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T4 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic DISEASE
T5 663-670 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T6 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T7 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T8 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T2 409-416 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T3 498-505 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T4 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic DISEASE
T5 663-670 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T6 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T7 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T8 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety DISEASE

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 87-91 OrganismTaxon denotes mice
T2 578-582 OrganismTaxon denotes mice
T3 706-710 OrganismTaxon denotes mice
T4 884-888 OrganismTaxon denotes mice

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-8 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T2 21-29 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T4 39-57 ChemicalEntity denotes pentylenetetrazole D010433
T5 104-112 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T6 117-125 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T8 152-170 ChemicalEntity denotes psychoactive drugs ChemicalEntity
T9 486-494 ChemicalEntity denotes nicotine D009538|http://purl.obolibrary.org/obo/CHEBI_18723
T11 517-525 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T13 538-553 ChemicalEntity denotes anxiogenic drug ChemicalEntity
T14 555-573 ChemicalEntity denotes pentylenetetrazole D010433
T15 732-740 ChemicalEntity denotes nicotine D009538|http://purl.obolibrary.org/obo/CHEBI_18723
T17 788-796 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T19 816-834 ChemicalEntity denotes pentylenetetrazole D010433
T20 1104-1112 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T21 1202-1210 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T23 1226-1244 ChemicalEntity denotes pentylenetetrazole D010433
T24 1339-1347 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T25 1386-1394 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T27 1404-1422 ChemicalEntity denotes pentylenetetrazole D010433
T28 1606-1614 ChemicalEntity denotes nicotine D009538|http://purl.obolibrary.org/obo/CHEBI_18723
T30 1618-1626 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T32 1658-1666 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732
T34 1781-1789 ChemicalEntity denotes nicotine D009538|http://purl.obolibrary.org/obo/CHEBI_18723
T36 1794-1802 ChemicalEntity denotes caffeine D002110|http://purl.obolibrary.org/obo/CHEBI_27732

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T36 1794-1802 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T34 1781-1789 ChemicalEntity denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723|D009538
T32 1658-1666 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T30 1618-1626 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T28 1606-1614 ChemicalEntity denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723|D009538
T27 1404-1422 ChemicalEntity denotes pentylenetetrazole D010433
T25 1386-1394 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T24 1339-1347 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T23 1226-1244 ChemicalEntity denotes pentylenetetrazole D010433
T21 1202-1210 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T20 1104-1112 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T19 816-834 ChemicalEntity denotes pentylenetetrazole D010433
T17 788-796 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T15 732-740 ChemicalEntity denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723|D009538
T14 555-573 ChemicalEntity denotes pentylenetetrazole D010433
T13 538-553 ChemicalEntity denotes anxiogenic drug ChemicalEntity
T11 517-525 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T9 486-494 ChemicalEntity denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723|D009538
T8 152-170 ChemicalEntity denotes psychoactive drugs ChemicalEntity
T6 117-125 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T5 104-112 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T4 39-57 ChemicalEntity denotes pentylenetetrazole D010433
T2 21-29 ChemicalEntity denotes caffeine http://purl.obolibrary.org/obo/CHEBI_27732|D002110
T1 0-8 ChemicalEntity denotes Nicotine http://purl.obolibrary.org/obo/CHEBI_17688
T39114 1681-1693 GeneOrGeneProduct denotes non-specific
T3289 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T7 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T88655 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T76927 663-670 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T70760 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic DISEASE
T3 498-505 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T17024 409-416 DiseaseOrPhenotypicFeature denotes anxiety DISEASE
T77307 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect DISEASE
T16991 884-888 OrganismTaxon denotes mice
T38843 706-710 OrganismTaxon denotes mice
T93447 578-582 OrganismTaxon denotes mice
T52943 87-91 OrganismTaxon denotes mice

biored-valid-deepseek-nr-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 87-91 OrganismTaxon denotes mice
T5 104-112 ChemicalEntity denotes Nicotine
T6 117-125 ChemicalEntity denotes caffeine
T7 486-494 ChemicalEntity denotes nicotine
T8 517-525 ChemicalEntity denotes caffeine
T9 555-573 ChemicalEntity denotes pentylenetetrazole
T10 578-582 OrganismTaxon denotes mice
T11 732-740 ChemicalEntity denotes nicotine
T12 788-796 ChemicalEntity denotes caffeine
T13 816-834 ChemicalEntity denotes pentylenetetrazole
T14 1104-1112 ChemicalEntity denotes Nicotine

biored-valid

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 152-170 ChemicalEntity denotes psychoactive drugs
T9 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T10 486-494 ChemicalEntity denotes nicotine
T11 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T12 517-525 ChemicalEntity denotes caffeine
T13 538-553 ChemicalEntity denotes anxiogenic drug
T14 555-573 ChemicalEntity denotes pentylenetetrazole
T15 578-582 OrganismTaxon denotes mice
T16 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T17 706-710 OrganismTaxon denotes mice
T18 732-740 ChemicalEntity denotes nicotine
T19 788-796 ChemicalEntity denotes caffeine
T20 816-834 ChemicalEntity denotes pentylenetetrazole
T21 884-888 OrganismTaxon denotes mice
T22 1104-1112 ChemicalEntity denotes Nicotine
T23 1202-1210 ChemicalEntity denotes caffeine
T24 1226-1244 ChemicalEntity denotes pentylenetetrazole
T25 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T26 1339-1347 ChemicalEntity denotes Nicotine
T27 1386-1394 ChemicalEntity denotes caffeine
T28 1404-1422 ChemicalEntity denotes pentylenetetrazole
T29 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T30 1606-1614 ChemicalEntity denotes nicotine
T31 1618-1626 ChemicalEntity denotes caffeine
T32 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety
T33 1658-1666 ChemicalEntity denotes caffeine
T34 1781-1789 ChemicalEntity denotes nicotine
T35 1794-1802 ChemicalEntity denotes caffeine

biored-valid-deepseek-nr-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 87-91 OrganismTaxon denotes mice
T5 104-112 ChemicalEntity denotes Nicotine
T6 117-125 ChemicalEntity denotes caffeine
T7 486-494 ChemicalEntity denotes nicotine
T8 517-525 ChemicalEntity denotes caffeine
T9 555-573 ChemicalEntity denotes pentylenetetrazole
T10 578-582 OrganismTaxon denotes mice
T11 608-611 DiseaseOrPhenotypicFeature denotes EPM
T12 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T13 732-740 ChemicalEntity denotes nicotine
T14 788-796 ChemicalEntity denotes caffeine
T15 816-834 ChemicalEntity denotes pentylenetetrazole

biored-valid-deepseek-r-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 87-91 OrganismTaxon denotes mice
T5 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T6 692-710 OrganismTaxon denotes Swiss Webster mice
T7 767-773 ChemicalEntity denotes saline

biored-valid-deepseek-r-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 104-112 ChemicalEntity denotes Nicotine
T5 117-125 ChemicalEntity denotes caffeine
T6 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T7 486-494 ChemicalEntity denotes nicotine
T8 517-525 ChemicalEntity denotes caffeine
T9 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T10 555-573 ChemicalEntity denotes pentylenetetrazole
T11 578-582 OrganismTaxon denotes mice
T12 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T13 706-710 OrganismTaxon denotes mice
T14 732-740 ChemicalEntity denotes nicotine
T15 788-796 ChemicalEntity denotes caffeine

biored-valid-gemini-nr-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-76 DiseaseOrPhenotypicFeature denotes anxiogenic
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T13 555-573 ChemicalEntity denotes pentylenetetrazole
T14 578-582 OrganismTaxon denotes mice
T15 687-705 OrganismTaxon denotes male Swiss Webster
T16 706-710 OrganismTaxon denotes mice
T17 767-773 ChemicalEntity denotes saline
T18 788-796 ChemicalEntity denotes caffeine
T19 816-834 ChemicalEntity denotes pentylenetetrazole
T20 1104-1112 ChemicalEntity denotes Nicotine
T21 1202-1210 ChemicalEntity denotes caffeine
T22 1226-1244 ChemicalEntity denotes pentylenetetrazole
T23 1268-1278 DiseaseOrPhenotypicFeature denotes anxiogenic
T24 1386-1394 ChemicalEntity denotes caffeine
T25 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T26 1606-1614 ChemicalEntity denotes nicotine
T27 1694-1704 DiseaseOrPhenotypicFeature denotes anxiolytic

biored-valid-gemini-r-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 555-573 ChemicalEntity denotes pentylenetetrazole
T13 578-582 OrganismTaxon denotes mice
T14 692-710 OrganismTaxon denotes Swiss Webster mice
T15 767-773 ChemicalEntity denotes saline
T16 788-796 ChemicalEntity denotes caffeine
T17 816-834 ChemicalEntity denotes pentylenetetrazole
T18 1104-1112 ChemicalEntity denotes Nicotine
T19 1202-1210 ChemicalEntity denotes caffeine
T20 1226-1244 ChemicalEntity denotes pentylenetetrazole
T21 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T22 1386-1394 ChemicalEntity denotes caffeine
T23 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T24 1606-1614 ChemicalEntity denotes nicotine
T25 1618-1642 DiseaseOrPhenotypicFeature denotes caffeine-induced anxiety
T26 1694-1711 DiseaseOrPhenotypicFeature denotes anxiolytic effect

biored-valid-gemini-r-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 555-573 ChemicalEntity denotes pentylenetetrazole
T13 578-582 OrganismTaxon denotes mice
T14 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T15 692-710 OrganismTaxon denotes Swiss Webster mice
T16 732-740 ChemicalEntity denotes nicotine
T17 788-796 ChemicalEntity denotes caffeine
T18 816-834 ChemicalEntity denotes pentylenetetrazole
T19 1104-1112 ChemicalEntity denotes Nicotine
T20 1202-1210 ChemicalEntity denotes caffeine
T21 1226-1244 ChemicalEntity denotes pentylenetetrazole
T22 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T23 1386-1394 ChemicalEntity denotes caffeine
T24 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T25 1606-1614 ChemicalEntity denotes nicotine
T26 1694-1711 DiseaseOrPhenotypicFeature denotes anxiolytic effect

biored-valid-gpt-nr-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 555-573 ChemicalEntity denotes pentylenetetrazole
T13 767-773 ChemicalEntity denotes saline
T14 788-796 ChemicalEntity denotes caffeine
T15 816-834 ChemicalEntity denotes pentylenetetrazole

biored-valid-gpt-r-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 87-91 OrganismTaxon denotes mice
T5 104-112 ChemicalEntity denotes Nicotine
T6 117-125 ChemicalEntity denotes caffeine
T7 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T8 486-494 ChemicalEntity denotes nicotine
T9 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T10 517-525 ChemicalEntity denotes caffeine
T11 555-573 ChemicalEntity denotes pentylenetetrazole
T12 578-582 OrganismTaxon denotes mice
T13 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T14 706-710 OrganismTaxon denotes mice
T15 732-740 ChemicalEntity denotes nicotine
T16 788-796 ChemicalEntity denotes caffeine
T17 816-834 ChemicalEntity denotes pentylenetetrazole
T18 884-888 OrganismTaxon denotes mice
T19 1104-1112 ChemicalEntity denotes Nicotine
T20 1202-1210 ChemicalEntity denotes caffeine
T21 1226-1244 ChemicalEntity denotes pentylenetetrazole
T22 1339-1347 ChemicalEntity denotes Nicotine
T23 1386-1394 ChemicalEntity denotes caffeine
T24 1404-1422 ChemicalEntity denotes pentylenetetrazole
T25 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T26 1606-1614 ChemicalEntity denotes nicotine
T27 1618-1626 ChemicalEntity denotes caffeine
T28 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety
T29 1781-1789 ChemicalEntity denotes nicotine
T30 1794-1802 ChemicalEntity denotes caffeine

biored-valid-gpt-nr-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 555-573 ChemicalEntity denotes pentylenetetrazole
T13 578-582 OrganismTaxon denotes mice
T14 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T15 706-710 OrganismTaxon denotes mice
T16 732-740 ChemicalEntity denotes nicotine
T17 788-796 ChemicalEntity denotes caffeine
T18 816-834 ChemicalEntity denotes pentylenetetrazole
T19 884-888 OrganismTaxon denotes mice
T20 1104-1112 ChemicalEntity denotes Nicotine
T21 1202-1210 ChemicalEntity denotes caffeine
T22 1226-1244 ChemicalEntity denotes pentylenetetrazole
T23 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T24 1339-1347 ChemicalEntity denotes Nicotine
T25 1386-1394 ChemicalEntity denotes caffeine
T26 1404-1422 ChemicalEntity denotes pentylenetetrazole
T27 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T28 1606-1614 ChemicalEntity denotes nicotine
T29 1618-1626 ChemicalEntity denotes caffeine
T30 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety
T31 1694-1711 DiseaseOrPhenotypicFeature denotes anxiolytic effect
T32 1781-1789 ChemicalEntity denotes nicotine
T33 1794-1802 ChemicalEntity denotes caffeine

biored-valid-gpt-r-ng

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-83 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 295-302 OrganismTaxon denotes animals
T9 409-426 DiseaseOrPhenotypicFeature denotes anxiety responses
T10 486-494 ChemicalEntity denotes nicotine
T11 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T12 517-525 ChemicalEntity denotes caffeine
T13 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T14 555-573 ChemicalEntity denotes pentylenetetrazole
T15 578-582 OrganismTaxon denotes mice
T16 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T17 692-710 OrganismTaxon denotes Swiss Webster mice
T18 732-740 ChemicalEntity denotes nicotine
T19 767-773 ChemicalEntity denotes saline
T20 788-796 ChemicalEntity denotes caffeine
T21 816-834 ChemicalEntity denotes pentylenetetrazole
T22 884-888 OrganismTaxon denotes mice
T23 985-1003 DiseaseOrPhenotypicFeature denotes Locomotor activity
T24 1104-1112 ChemicalEntity denotes Nicotine
T25 1202-1210 ChemicalEntity denotes caffeine
T26 1226-1244 ChemicalEntity denotes pentylenetetrazole
T27 1268-1285 DiseaseOrPhenotypicFeature denotes anxiogenic effect
T28 1339-1347 ChemicalEntity denotes Nicotine
T29 1386-1394 ChemicalEntity denotes caffeine
T30 1404-1422 ChemicalEntity denotes pentylenetetrazole
T31 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T32 1521-1539 DiseaseOrPhenotypicFeature denotes locomotor activity
T33 1606-1614 ChemicalEntity denotes nicotine
T34 1618-1626 ChemicalEntity denotes caffeine
T35 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety
T36 1694-1711 DiseaseOrPhenotypicFeature denotes anxiolytic effect
T37 1781-1789 ChemicalEntity denotes nicotine
T38 1794-1802 ChemicalEntity denotes caffeine

biored-valid-gemini-nr-g

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-76 DiseaseOrPhenotypicFeature denotes anxiogenic
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T13 555-573 ChemicalEntity denotes pentylenetetrazole
T14 578-582 OrganismTaxon denotes mice
T15 687-710 OrganismTaxon denotes male Swiss Webster mice
T16 767-773 ChemicalEntity denotes saline
T17 788-796 ChemicalEntity denotes caffeine
T18 816-834 ChemicalEntity denotes pentylenetetrazole
T19 1104-1112 ChemicalEntity denotes Nicotine
T20 1202-1210 ChemicalEntity denotes caffeine
T21 1226-1244 ChemicalEntity denotes pentylenetetrazole
T22 1268-1278 DiseaseOrPhenotypicFeature denotes anxiogenic
T23 1386-1394 ChemicalEntity denotes caffeine
T24 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T25 1606-1614 ChemicalEntity denotes nicotine
T26 1694-1704 DiseaseOrPhenotypicFeature denotes anxiolytic

biored-valid-gpt-r-m

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 87-91 OrganismTaxon denotes mice
T5 104-112 ChemicalEntity denotes Nicotine
T6 117-125 ChemicalEntity denotes caffeine
T7 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T8 486-494 ChemicalEntity denotes nicotine
T9 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T10 517-525 ChemicalEntity denotes caffeine
T11 555-573 ChemicalEntity denotes pentylenetetrazole
T12 578-582 OrganismTaxon denotes mice
T13 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T14 692-710 OrganismTaxon denotes Swiss Webster mice
T15 732-740 ChemicalEntity denotes nicotine
T16 788-796 ChemicalEntity denotes caffeine
T17 816-834 ChemicalEntity denotes pentylenetetrazole
T18 884-888 OrganismTaxon denotes mice
T19 1104-1112 ChemicalEntity denotes Nicotine
T20 1202-1210 ChemicalEntity denotes caffeine
T21 1226-1244 ChemicalEntity denotes pentylenetetrazole
T22 1339-1347 ChemicalEntity denotes Nicotine
T23 1386-1394 ChemicalEntity denotes caffeine
T24 1404-1422 ChemicalEntity denotes pentylenetetrazole
T25 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T26 1606-1614 ChemicalEntity denotes nicotine
T27 1618-1626 ChemicalEntity denotes caffeine
T28 1635-1642 DiseaseOrPhenotypicFeature denotes anxiety
T29 1781-1789 ChemicalEntity denotes nicotine
T30 1794-1802 ChemicalEntity denotes caffeine

biored-valid-gemini-r-m

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-76 DiseaseOrPhenotypicFeature denotes anxiogenic
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 486-494 ChemicalEntity denotes nicotine
T10 498-505 DiseaseOrPhenotypicFeature denotes anxiety
T11 517-525 ChemicalEntity denotes caffeine
T12 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T13 555-573 ChemicalEntity denotes pentylenetetrazole
T14 578-582 OrganismTaxon denotes mice
T15 692-710 OrganismTaxon denotes Swiss Webster mice
T16 732-740 ChemicalEntity denotes nicotine
T17 788-796 ChemicalEntity denotes caffeine
T18 816-834 ChemicalEntity denotes pentylenetetrazole
T19 1104-1112 ChemicalEntity denotes Nicotine
T20 1202-1210 ChemicalEntity denotes caffeine
T21 1226-1244 ChemicalEntity denotes pentylenetetrazole
T22 1386-1394 ChemicalEntity denotes caffeine
T23 1431-1438 DiseaseOrPhenotypicFeature denotes anxiety
T24 1606-1614 ChemicalEntity denotes nicotine
T25 1694-1704 DiseaseOrPhenotypicFeature denotes anxiolytic

biored-valid-deepseek-r-m

Id Subject Object Predicate Lexical cue
T1 0-8 ChemicalEntity denotes Nicotine
T2 21-29 ChemicalEntity denotes caffeine
T3 39-57 ChemicalEntity denotes pentylenetetrazole
T4 66-76 DiseaseOrPhenotypicFeature denotes anxiogenic
T5 87-91 OrganismTaxon denotes mice
T6 104-112 ChemicalEntity denotes Nicotine
T7 117-125 ChemicalEntity denotes caffeine
T8 409-416 DiseaseOrPhenotypicFeature denotes anxiety
T9 517-525 ChemicalEntity denotes caffeine
T10 538-548 DiseaseOrPhenotypicFeature denotes anxiogenic
T11 555-573 ChemicalEntity denotes pentylenetetrazole
T12 578-582 OrganismTaxon denotes mice
T13 663-670 DiseaseOrPhenotypicFeature denotes anxiety
T14 788-796 ChemicalEntity denotes caffeine
T15 1104-1112 ChemicalEntity denotes Nicotine