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PubMed:15932919 JSONTXT

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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 142-158 Cell denotes epithelial cells http://purl.obolibrary.org/obo/CL:0000066
T2 876-887 Cell denotes cancer cell http://purl.obolibrary.org/obo/CL:0001064
T3 1325-1347 Cell denotes prostate stromal cells http://purl.obolibrary.org/obo/CL:0002622
T4 1848-1860 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 102-218 DRI_Background denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T2 219-268 DRI_Outcome denotes Previously, we have shown that expression of core
T3 290-384 DRI_Outcome denotes is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 DRI_Outcome denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 DRI_Challenge denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 DRI_Approach denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 DRI_Approach denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1056 DRI_Background denotes When
T9 1080-1221 DRI_Background denotes cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than
T10 1245-1251 DRI_Background denotes cells.
T11 1252-1519 DRI_Approach denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T12 1520-1630 DRI_Outcome denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T13 1631-1881 DRI_Background denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 14-20 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T2 264-270 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T3 428-434 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
TextSentencer_T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
TextSentencer_T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
TextSentencer_T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
TextSentencer_T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
TextSentencer_T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
TextSentencer_T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
TextSentencer_T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
TextSentencer_T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
TextSentencer_T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
TextSentencer_T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.
T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.
T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 73-81 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T2 317-323 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessel
T3 358-363 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T4 368-372 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T5 537-545 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T6 696-704 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T7 784-792 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T8 867-875 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T9 1128-1136 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T10 1201-1209 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T11 1325-1333 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T12 1602-1610 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T13 1683-1691 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T14 1839-1847 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate

uniprot-human

Id Subject Object Predicate Lexical cue
T1 29-60 http://www.uniprot.org/uniprot/Q06430 denotes N-acetylglucosaminyltransferase
T2 443-474 http://www.uniprot.org/uniprot/Q06430 denotes N-acetylglucosaminyltransferase
T3 29-60 http://www.uniprot.org/uniprot/Q8N0V5 denotes N-acetylglucosaminyltransferase
T4 443-474 http://www.uniprot.org/uniprot/Q8N0V5 denotes N-acetylglucosaminyltransferase
T5 29-60 http://www.uniprot.org/uniprot/Q8NFS9 denotes N-acetylglucosaminyltransferase
T6 443-474 http://www.uniprot.org/uniprot/Q8NFS9 denotes N-acetylglucosaminyltransferase
T7 264-279 http://www.uniprot.org/uniprot/Q02742 denotes core 2-branched
T8 696-721 http://www.uniprot.org/uniprot/P07288 denotes prostate-specific antigen
T9 723-726 http://www.uniprot.org/uniprot/P07288 denotes PSA
T10 696-721 http://www.uniprot.org/uniprot/Q16305 denotes prostate-specific antigen
T11 723-726 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T12 723-726 http://www.uniprot.org/uniprot/P55786 denotes PSA

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 29-60 http://www.uniprot.org/uniprot/P97402 denotes N-acetylglucosaminyltransferase
T2 443-474 http://www.uniprot.org/uniprot/P97402 denotes N-acetylglucosaminyltransferase
T3 723-726 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T4 1140-1144 http://www.uniprot.org/uniprot/Q9CZA6 denotes nude

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 82-88 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T2 153-158 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 373-383 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinomas
T4 546-552 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T5 793-799 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T6 876-882 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T7 1080-1085 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T8 1166-1171 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T9 1245-1250 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T10 1294-1299 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T11 1342-1347 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T12 1398-1403 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T13 1434-1439 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T14 1611-1617 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T15 1692-1701 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T16 1702-1707 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T17 1848-1854 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T18 1855-1860 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 1809-1819 http://purl.obolibrary.org/obo/GO_0002118 denotes aggressive
T2 1826-1835 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

GO-CC

Id Subject Object Predicate Lexical cue
T1 14-18 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T2 264-268 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T3 428-432 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T4 102-106 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T5 153-158 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6 1080-1085 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T7 1166-1171 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8 1245-1250 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9 1294-1299 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T10 1342-1347 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T11 1398-1403 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12 1434-1439 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T13 1702-1707 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14 883-887 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T15 102-114 http://purl.obolibrary.org/obo/GO_0009986 denotes Cell surface

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 317-323 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T2 358-363 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T3 368-372 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 73-81 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T2 317-323 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessel
T3 358-363 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T4 368-372 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T5 537-545 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T6 696-704 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T7 784-792 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T8 867-875 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T9 1128-1136 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T10 1201-1209 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T11 1325-1333 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T12 1602-1610 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T13 1683-1691 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate
T14 1839-1847 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostate

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 723-726 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 368-372 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 317-323 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
PD-UBERON-AE-B_T3 358-363 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 73-88 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 200-205 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 368-383 Disease denotes lung carcinomas http://purl.obolibrary.org/obo/MONDO_0005138
T4 537-552 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T5 784-799 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T6 839-844 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T7 867-882 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T8 1201-1216 Disease denotes prostate tumors http://purl.obolibrary.org/obo/MONDO_0021259
T9 1602-1617 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T10 1683-1701 Disease denotes prostate carcinoma http://purl.obolibrary.org/obo/MONDO_0005159
T11 1820-1825 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T12 1839-1854 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 73-88 Phenotype denotes prostate cancer HP:0012125
T2 200-205 Phenotype denotes tumor HP:0002664
T3 373-383 Phenotype denotes carcinomas HP:0030731
T4 537-552 Phenotype denotes prostate cancer HP:0012125
T5 784-799 Phenotype denotes prostate cancer HP:0012125
T6 839-844 Phenotype denotes tumor HP:0002664
T7 867-882 Phenotype denotes prostate cancer HP:0012125
T8 1602-1617 Phenotype denotes prostate cancer HP:0012125
T9 1692-1701 Phenotype denotes carcinoma HP:0030731
T10 1809-1819 Phenotype denotes aggressive HP:0000718
T11 1820-1825 Phenotype denotes tumor HP:0002664
T12 1839-1854 Phenotype denotes prostate cancer HP:0012125

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 14-20 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 264-270 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 428-434 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 73-88 Phenotype denotes prostate cancer HP:0012125
T2 200-205 Phenotype denotes tumor HP:0002664
T3 373-383 Phenotype denotes carcinomas HP:0030731
T4 537-552 Phenotype denotes prostate cancer HP:0012125
T5 784-799 Phenotype denotes prostate cancer HP:0012125
T6 839-844 Phenotype denotes tumor HP:0002664
T7 867-882 Phenotype denotes prostate cancer HP:0012125
T8 1602-1617 Phenotype denotes prostate cancer HP:0012125
T9 1692-1701 Phenotype denotes carcinoma HP:0030731
T10 1820-1825 Phenotype denotes tumor HP:0002664
T11 1839-1854 Phenotype denotes prostate cancer HP:0012125

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 73-88 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 200-205 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 368-383 Disease denotes lung carcinomas http://purl.obolibrary.org/obo/MONDO_0005138
T4 537-552 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T5 784-799 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T6 839-844 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T7 867-882 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T8 1201-1216 Disease denotes prostate tumors http://purl.obolibrary.org/obo/MONDO_0021259
T9 1602-1617 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T10 1683-1701 Disease denotes prostate carcinoma http://purl.obolibrary.org/obo/MONDO_0005159
T11 1820-1825 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T12 1839-1854 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 556-561 OrganismTaxon denotes human 9606
T2 1145-1149 OrganismTaxon denotes mice 10088

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 142-158 Cell denotes epithelial cells http://purl.obolibrary.org/obo/CL:0000066
T2 876-887 Cell denotes cancer cell http://purl.obolibrary.org/obo/CL:0001064
T3 1325-1347 Cell denotes prostate stromal cells http://purl.obolibrary.org/obo/CL:0002622
T4 1848-1860 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 73-81 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 142-158 Body_part denotes epithelial cells http://purl.obolibrary.org/obo/CL_0000066
T3 317-323 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T4 358-363 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T5 368-372 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 537-545 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T7 696-704 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T8 784-792 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T9 867-875 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T10 1128-1136 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T11 1201-1209 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T12 1325-1347 Body_part denotes prostate stromal cells http://purl.obolibrary.org/obo/CL_0002622
T13 1602-1610 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T14 1683-1691 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T15 1839-1847 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 73-81 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 317-323 Body_part denotes vessel http://purl.obolibrary.org/obo/MAT_0000393
T3 358-363 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T4 368-372 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T5 537-545 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T6 696-704 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T7 784-792 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T8 867-875 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T9 1128-1136 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T10 1201-1209 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T11 1325-1333 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T12 1602-1610 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T13 1683-1691 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T14 1839-1847 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
TextSentencer_T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
TextSentencer_T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
TextSentencer_T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
TextSentencer_T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
TextSentencer_T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
TextSentencer_T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
TextSentencer_T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
TextSentencer_T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
TextSentencer_T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
TextSentencer_T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.
T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.
T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression.
T2 102-218 Sentence denotes Cell surface carbohydrates expressed on epithelial cells are thought to play an important role in tumor progression.
T3 219-384 Sentence denotes Previously, we have shown that expression of core 2-branched O-glycans is closely correlated with vessel invasion and depth of invasion in colon and lung carcinomas.
T4 385-571 Sentence denotes In this study, we found that expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1, Core2GnT, is positively correlated with the progression of prostate cancer in human patients.
T5 572-736 Sentence denotes Statistical analysis demonstrated that Core2GnT is an independent predictor for progressed pathological stage (pT3) and for prostate-specific antigen (PSA) relapse.
T6 737-893 Sentence denotes To determine directly the roles of Core2GnT in prostate cancer progression, we set up an experimental tumor model using the LNCaP prostate cancer cell line.
T7 894-1051 Sentence denotes Because this line does not express Core2GnT, we established an LNCaP line stably expressing Core2GnT, LNCap-Core2GnT, by transfecting cDNA encoding Core2GnT.
T8 1052-1251 Sentence denotes When mock-transfected LNCaP cells and LNCaP-Core2GnT were inoculated in the prostate of nude mice, LNCaP-Core2GnT cells produced three times heavier prostate tumors than mock-transfected LNCaP cells.
T9 1252-1519 Sentence denotes Furthermore, we found that LNCaP-Core2GnT cells adhered more strongly to prostate stromal cells, type IV collagen and laminin than did LNCaP-mock cells, but LNCaP and LNCaP-Core2GnT cells grew almost at the same rate on plates coated with type IV collagen or laminin.
T10 1520-1630 Sentence denotes These results indicate that Core2GnT is an extremely useful prognostic marker for prostate cancer progression.
T11 1631-1881 Sentence denotes The results also suggest that acquiring Core2GnT in prostate carcinoma cells facilitates adhesion to type IV collagen and laminin, and this increased adhesion may be a cause for aggressive tumor formation by prostate cancer cells expressing Core2GnT.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 14-20 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 264-270 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 428-434 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 723-726 Lectin denotes PSA GL_000021

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 556-561 OrganismTaxon denotes human 9606
T2 1145-1149 OrganismTaxon denotes mice 10088

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 73-81 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 142-158 Body_part denotes epithelial cells http://purl.obolibrary.org/obo/CL_0000066
T3 317-323 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T4 358-363 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T5 368-372 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 537-545 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T7 696-704 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T8 784-792 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T9 867-875 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T10 1128-1136 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T11 1201-1209 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T12 1325-1347 Body_part denotes prostate stromal cells http://purl.obolibrary.org/obo/CL_0002622
T13 1602-1610 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T14 1683-1691 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T15 1839-1847 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 73-81 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 317-323 Body_part denotes vessel http://purl.obolibrary.org/obo/MAT_0000393
T3 358-363 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T4 368-372 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T5 537-545 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T6 696-704 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T7 784-792 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T8 867-875 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T9 1128-1136 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T10 1201-1209 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T11 1325-1333 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T12 1602-1610 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T13 1683-1691 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T14 1839-1847 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078