PubMed:1590590 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/1590590","sourcedb":"PubMed","sourceid":"1590590","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/1590590","text":"Supercritical fluid extraction of active components in a drug formulation.\nSulfamethoxazole and trimethoprim have been extracted from a drug formulation, Septra Infusion, with pure supercritical carbon dioxide. Both direct extraction of the aqueous-based matrix and indirect extraction of the formulation immobilized onto Celite were studied. Exhaustive analytical extraction was achieved when active components were less than 1.0 mg. A number of co-extractants were found, but each was blind to the HPLC/UV assay.","tracks":[{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":14,"end":19},"obj":"Body_part"},{"id":"T2","span":{"begin":255,"end":261},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0006314"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0027368"},{"subj":"T1","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T2","pred":"source","obj":"Anatomy-UBERON"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Anatomy-UBERON","color":"#ec9f93","default":true}]}]}}