PubMed:15811908
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-54 | Sentence | denotes | Pheochromocytoma unmasked by amisulpride and tiapride. |
| T2 | 55-65 | Sentence | denotes | OBJECTIVE: |
| T3 | 66-163 | Sentence | denotes | To describe the unmasking of pheochromocytoma in a patient treated with amisulpride and tiapride. |
| T4 | 164-177 | Sentence | denotes | CASE SUMMARY: |
| T5 | 178-337 | Sentence | denotes | A 42-year-old white man developed acute hypertension with severe headache and vomiting 2 hours after the first doses of amisulpride 100 mg and tiapride 100 mg. |
| T6 | 338-459 | Sentence | denotes | Both drugs were immediately discontinued, and the patient recovered after subsequent nicardipine and verapamil treatment. |
| T7 | 460-590 | Sentence | denotes | Abdominal ultrasound showed an adrenal mass, and postoperative histologic examination confirmed the diagnosis of pheochromocytoma. |
| T8 | 591-602 | Sentence | denotes | DISCUSSION: |
| T9 | 603-751 | Sentence | denotes | Drug-induced symptoms of pheochromocytoma are often associated with the use of substituted benzamide drugs, but the underlying mechanism is unknown. |
| T10 | 752-905 | Sentence | denotes | In our case, use of the Naranjo probability scale indicated a possible relationship between the hypertensive crisis and amisulpride and tiapride therapy. |
| T11 | 906-918 | Sentence | denotes | CONCLUSIONS: |
| T12 | 919-1065 | Sentence | denotes | As of March 24, 2005, this is the first reported case of amisulpride- and tiapride-induced hypertensive crisis in a patient with pheochromocytoma. |
| T13 | 1066-1189 | Sentence | denotes | Physicians and other healthcare professionals should be aware of this potential adverse effect of tiapride and amisulpride. |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 198-201 | OrganismTaxon | denotes | man | NCBItxid:9606 |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 1657 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | MESH:D010673 |
| 1658 | 29-40 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
| 1659 | 45-53 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1660 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | MESH:D010673 |
| 1661 | 117-124 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 1662 | 138-149 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
| 1663 | 154-162 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1664 | 198-201 | OrganismTaxon | denotes | man | NCBITaxon:9606 |
| 1665 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | MESH:D006973 |
| 1666 | 243-251 | DiseaseOrPhenotypicFeature | denotes | headache | MESH:D006261 |
| 1667 | 256-264 | DiseaseOrPhenotypicFeature | denotes | vomiting | MESH:D014839 |
| 1668 | 298-309 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
| 1669 | 321-329 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1670 | 388-395 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 1671 | 423-434 | ChemicalEntity | denotes | nicardipine | MESH:D009529 |
| 1672 | 439-448 | ChemicalEntity | denotes | verapamil | MESH:D014700 |
| 1673 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | MESH:D010673 |
| 1674 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | MESH:D010673 |
| 1675 | 694-709 | ChemicalEntity | denotes | benzamide drugs | MESH:D001549 |
| 1676 | 848-860 | DiseaseOrPhenotypicFeature | denotes | hypertensive | MESH:D006973 |
| 1677 | 872-883 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
| 1678 | 888-896 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1679 | 976-987 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
| 1680 | 993-1001 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1681 | 1010-1022 | DiseaseOrPhenotypicFeature | denotes | hypertensive | MESH:D006973 |
| 1682 | 1035-1042 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
| 1683 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | MESH:D010673 |
| 1684 | 1164-1172 | ChemicalEntity | denotes | tiapride | MESH:D063325 |
| 1685 | 1177-1188 | ChemicalEntity | denotes | amisulpride | MESH:D000077582 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | 0008233 |
| T2 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233 |
| T3 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233 |
| T4 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233 |
| T5 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 112-116 | GeneOrGeneProduct | denotes | in a |
| T2 | 164-168 | GeneOrGeneProduct | denotes | CASE |
| T3 | 183-187 | GeneOrGeneProduct | denotes | year |
| T4 | 192-197 | GeneOrGeneProduct | denotes | white |
| T5 | 218-230 | GeneOrGeneProduct | denotes | hypertension |
| T6 | 314-316 | GeneOrGeneProduct | denotes | mg |
| T7 | 334-336 | GeneOrGeneProduct | denotes | mg |
| T8 | 460-469 | GeneOrGeneProduct | denotes | Abdominal |
| T9 | 499-503 | GeneOrGeneProduct | denotes | mass |
| T10 | 608-615 | GeneOrGeneProduct | denotes | induced |
| T11 | 743-750 | GeneOrGeneProduct | denotes | unknown |
| T12 | 759-763 | GeneOrGeneProduct | denotes | case |
| T13 | 784-795 | GeneOrGeneProduct | denotes | probability |
| T14 | 848-860 | GeneOrGeneProduct | denotes | hypertensive |
| T15 | 925-930 | GeneOrGeneProduct | denotes | March |
| T16 | 968-972 | GeneOrGeneProduct | denotes | case |
| T17 | 1002-1009 | GeneOrGeneProduct | denotes | induced |
| T18 | 1010-1022 | GeneOrGeneProduct | denotes | hypertensive |
| T19 | 1030-1034 | GeneOrGeneProduct | denotes | in a |
| T20 | 1081-1086 | GeneOrGeneProduct | denotes | other |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 192-197 | GeneOrGeneProduct | denotes | white |
| T2 | 218-230 | GeneOrGeneProduct | denotes | hypertension |
| T3 | 460-469 | GeneOrGeneProduct | denotes | Abdominal |
| T4 | 743-750 | GeneOrGeneProduct | denotes | unknown |
| T5 | 1081-1086 | GeneOrGeneProduct | denotes | other |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | D010673 |
| T2 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T3 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | D006973 |
| T4 | 243-251 | DiseaseOrPhenotypicFeature | denotes | headache | D006261 |
| T5 | 256-264 | DiseaseOrPhenotypicFeature | denotes | vomiting | D014839 |
| T6 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T7 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T8 | 848-860 | DiseaseOrPhenotypicFeature | denotes | hypertensive | D006973 |
| T9 | 1010-1022 | DiseaseOrPhenotypicFeature | denotes | hypertensive | D006973 |
| T10 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 192-197 | GeneOrGeneProduct | denotes | white |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | 0008233|0004974 |
| T3 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233|0004974 |
| T5 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | 0005044 |
| T6 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233|0004974 |
| T8 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233|0004974 |
| T10 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | 0008233|0004974 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | D010673 |
| T2 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T3 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | D006973 |
| T4 | 243-251 | DiseaseOrPhenotypicFeature | denotes | headache | D006261 |
| T5 | 256-264 | DiseaseOrPhenotypicFeature | denotes | vomiting | D014839 |
| T6 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T7 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T8 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | D010673 |
| T2 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T3 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | D006973 |
| T4 | 243-251 | DiseaseOrPhenotypicFeature | denotes | headache | D006261 |
| T5 | 256-264 | DiseaseOrPhenotypicFeature | denotes | vomiting | D014839 |
| T6 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T7 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
| T8 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 117-124 | OrganismTaxon | denotes | patient |
| T2 | 198-201 | OrganismTaxon | denotes | man |
| T3 | 388-395 | OrganismTaxon | denotes | patient |
| T4 | 1035-1042 | OrganismTaxon | denotes | patient |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 29-40 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
| T3 | 45-53 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T5 | 138-149 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
| T7 | 154-162 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T9 | 298-309 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
| T11 | 321-329 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T13 | 423-434 | ChemicalEntity | denotes | nicardipine | D009529 |
| T14 | 439-448 | ChemicalEntity | denotes | verapamil | D014700|http://purl.obolibrary.org/obo/CHEBI_9948 |
| T16 | 694-703 | ChemicalEntity | denotes | benzamide | C037689|http://purl.obolibrary.org/obo/CHEBI_28179 |
| T18 | 872-883 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
| T20 | 888-896 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T22 | 976-987 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
| T24 | 993-1001 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T26 | 1164-1172 | ChemicalEntity | denotes | tiapride | D063325|ChemicalEntity |
| T28 | 1177-1188 | ChemicalEntity | denotes | amisulpride | D000077582|http://purl.obolibrary.org/obo/CHEBI_64045 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T28 | 1177-1188 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T26 | 1164-1172 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T24 | 993-1001 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T22 | 976-987 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T20 | 888-896 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T18 | 872-883 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T16 | 694-703 | ChemicalEntity | denotes | benzamide | http://purl.obolibrary.org/obo/CHEBI_28179|C037689 | |
| T14 | 439-448 | ChemicalEntity | denotes | verapamil | http://purl.obolibrary.org/obo/CHEBI_9948|D014700 | |
| T13 | 423-434 | ChemicalEntity | denotes | nicardipine | D009529 | |
| T11 | 321-329 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T9 | 298-309 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T7 | 154-162 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T5 | 138-149 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T3 | 45-53 | ChemicalEntity | denotes | tiapride | ChemicalEntity|D063325 | |
| T1 | 29-40 | ChemicalEntity | denotes | amisulpride | http://purl.obolibrary.org/obo/CHEBI_64045|D000077582 | |
| T77781 | 192-197 | GeneOrGeneProduct | denotes | white | ||
| T8 | 1048-1064 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 | |
| T348 | 628-644 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 | |
| T6 | 573-589 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 | |
| T53992 | 256-264 | DiseaseOrPhenotypicFeature | denotes | vomiting | D014839 | |
| T4 | 243-251 | DiseaseOrPhenotypicFeature | denotes | headache | D006261 | |
| T76951 | 218-230 | DiseaseOrPhenotypicFeature | denotes | hypertension | D006973 | |
| T2 | 95-111 | DiseaseOrPhenotypicFeature | denotes | pheochromocytoma | D010673 | |
| T62985 | 0-16 | DiseaseOrPhenotypicFeature | denotes | Pheochromocytoma | D010673 | |
| T51954 | 1035-1042 | OrganismTaxon | denotes | patient | ||
| T16523 | 388-395 | OrganismTaxon | denotes | patient | ||
| T29829 | 198-201 | OrganismTaxon | denotes | man | ||
| T32484 | 117-124 | OrganismTaxon | denotes | patient |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TI1 | 0-16 | HP:0002666 | denotes | Pheochromocytoma |
| AB1 | 95-111 | HP:0002666 | denotes | pheochromocytoma |
| AB2 | 218-230 | HP:0000822 | denotes | hypertension |
| AB3 | 243-251 | HP:0002315 | denotes | headache |
| AB4 | 256-264 | HP:0002013 | denotes | vomiting |
| AB5 | 573-589 | HP:0002666 | denotes | pheochromocytoma |
| AB6 | 628-644 | HP:0002666 | denotes | pheochromocytoma |
| AB7 | 848-867 | HP:0100735 | denotes | hypertensive crisis |
| AB8 | 1010-1029 | HP:0100735 | denotes | hypertensive crisis |
| AB9 | 1048-1064 | HP:0002666 | denotes | pheochromocytoma |
bc5cdr-valid-experiment
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-16 | Disease | denotes | Pheochromocytoma |
| T2 | 29-40 | Chemical | denotes | amisulpride |
| T3 | 45-53 | Chemical | denotes | tiapride |
| T4 | 95-111 | Disease | denotes | pheochromocytoma |
| T5 | 138-149 | Chemical | denotes | amisulpride |
| T6 | 154-162 | Chemical | denotes | tiapride |
| T7 | 218-230 | Disease | denotes | hypertension |
| T8 | 243-251 | Disease | denotes | headache |
| T9 | 256-264 | Disease | denotes | vomiting |
| T10 | 298-309 | Chemical | denotes | amisulpride |
| T11 | 321-329 | Chemical | denotes | tiapride |
| T12 | 423-434 | Chemical | denotes | nicardipine |
| T13 | 439-448 | Chemical | denotes | verapamil |
| T14 | 573-589 | Disease | denotes | pheochromocytoma |
| T15 | 628-644 | Disease | denotes | pheochromocytoma |
| T16 | 694-703 | Chemical | denotes | benzamide |
| T17 | 848-860 | Disease | denotes | hypertensive |
| T18 | 872-883 | Chemical | denotes | amisulpride |
| T19 | 888-896 | Chemical | denotes | tiapride |
| T20 | 976-987 | Chemical | denotes | amisulpride |
| T21 | 993-1001 | Chemical | denotes | tiapride |
| T22 | 1010-1022 | Disease | denotes | hypertensive |
| T23 | 1048-1064 | Disease | denotes | pheochromocytoma |
| T24 | 1164-1172 | Chemical | denotes | tiapride |
| T25 | 1177-1188 | Chemical | denotes | amisulpride |