PubMed:15659616
Annnotations
Glycan-Motif
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 33-44 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T2 | 33-44 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T3 | 203-214 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T4 | 203-214 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T5 | 1027-1038 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T6 | 1027-1038 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T7 | 1310-1321 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T8 | 1310-1321 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 33-44 | Glycan_Motif | denotes | seminolipid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ |
T3 | 203-214 | Glycan_Motif | denotes | seminolipid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ |
T5 | 1027-1038 | Glycan_Motif | denotes | seminolipid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ |
T7 | 1310-1321 | Glycan_Motif | denotes | seminolipid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 33-44 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T2 | 33-44 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T3 | 203-214 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T4 | 203-214 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T5 | 1027-1038 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T6 | 1027-1038 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
T7 | 1310-1321 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | seminolipid |
T8 | 1310-1321 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | seminolipid |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 1235-1242 | http://www.glycoepitope.jp/epitopes/AN0216 | denotes | Sulph-1 |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-6 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | Testis |
T2 | 63-72 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cell |
T3 | 147-153 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
T4 | 390-394 | http://purl.obolibrary.org/obo/MAT_0000029 | denotes | male |
T5 | 543-553 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cells |
T6 | 669-678 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cell |
T7 | 826-846 | http://purl.obolibrary.org/obo/MAT_0000503 | denotes | seminiferous tubules |
T8 | 859-865 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
T9 | 979-985 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 390-406 | http://purl.bioontology.org/ontology/ICD10/N46 | denotes | male infertility |
uniprot-human
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 290-319 | http://www.uniprot.org/uniprot/Q99999 | denotes | sulfotransferase, cerebroside |
T2 | 338-341 | http://www.uniprot.org/uniprot/Q99999 | denotes | CST |
T3 | 850-853 | http://www.uniprot.org/uniprot/Q99999 | denotes | CST |
T4 | 1262-1265 | http://www.uniprot.org/uniprot/Q99999 | denotes | CST |
T5 | 338-341 | http://www.uniprot.org/uniprot/Q9NXC6 | denotes | CST |
T6 | 850-853 | http://www.uniprot.org/uniprot/Q9NXC6 | denotes | CST |
T7 | 1262-1265 | http://www.uniprot.org/uniprot/Q9NXC6 | denotes | CST |
uniprot-mouse
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 290-319 | http://www.uniprot.org/uniprot/Q9JHE4 | denotes | sulfotransferase, cerebroside |
T2 | 362-365 | http://www.uniprot.org/uniprot/Q9JHE4 | denotes | Cst |
T3 | 362-365 | http://www.uniprot.org/uniprot/Q9CWL2 | denotes | Cst |
GlycoBiology-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 68-81 | http://purl.bioontology.org/ontology/STY/T043 | denotes | cell function |
T2 | 529-542 | http://purl.bioontology.org/ontology/STY/T043 | denotes | cell function |
T3 | 548-553 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T4 | 565-570 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T5 | 629-637 | http://purl.bioontology.org/ontology/STY/T033 | denotes | findings |
T6 | 897-902 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T7 | 991-999 | http://purl.bioontology.org/ontology/STY/T033 | denotes | findings |
T8 | 1342-1345 | http://purl.bioontology.org/ontology/NCBITAXON/82391 | denotes | day |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 85-100 | http://purl.obolibrary.org/obo/GO_0007283 | denotes | spermatogenesis |
T2 | 428-443 | http://purl.obolibrary.org/obo/GO_0007283 | denotes | spermatogenesis |
T3 | 926-941 | http://purl.obolibrary.org/obo/GO_0007283 | denotes | spermatogenesis |
T4 | 175-183 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfated |
T5 | 220-229 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfation |
T6 | 457-466 | http://purl.obolibrary.org/obo/GO_0051323 | denotes | metaphase |
T7 | 480-487 | http://purl.obolibrary.org/obo/GO_0007126 | denotes | meiosis |
T8 | 480-487 | http://purl.obolibrary.org/obo/GO_0051321 | denotes | meiosis |
T9 | 957-964 | http://purl.obolibrary.org/obo/GO_0007126 | denotes | meiosis |
T10 | 957-964 | http://purl.obolibrary.org/obo/GO_0051321 | denotes | meiosis |
T11 | 1351-1354 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | age |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 1225-1233 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibody |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 68-72 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T2 | 529-533 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T3 | 548-553 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T4 | 565-570 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5 | 897-902 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T6 | 264-269 | http://purl.obolibrary.org/obo/GO_0005794 | denotes | Golgi |
T7 | 264-278 | http://purl.obolibrary.org/obo/GO_0000139 | denotes | Golgi membrane |
T8 | 264-289 | http://purl.obolibrary.org/obo/GO_0030660 | denotes | Golgi membrane-associated |
T9 | 270-278 | http://purl.obolibrary.org/obo/GO_0016020 | denotes | membrane |
T10 | 1066-1075 | http://purl.obolibrary.org/obo/GO_0016020 | denotes | membranes |
T11 | 839-846 | http://purl.obolibrary.org/obo/GO_0097649 | denotes | tubules |
T12 | 1059-1075 | http://purl.obolibrary.org/obo/GO_0005886 | denotes | plasma membranes |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-6 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | Testis |
T2 | 147-153 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
T3 | 859-865 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
T4 | 979-985 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
GlycoBiology-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-6 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | Testis |
T2 | 63-72 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cell |
T3 | 147-153 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
T4 | 390-394 | http://purl.obolibrary.org/obo/MAT_0000029 | denotes | male |
T5 | 543-553 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cells |
T6 | 669-678 | http://purl.obolibrary.org/obo/MAT_0000334 | denotes | germ cell |
T7 | 826-846 | http://purl.obolibrary.org/obo/MAT_0000503 | denotes | seminiferous tubules |
T8 | 859-865 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
T9 | 979-985 | http://purl.obolibrary.org/obo/MAT_0000132 | denotes | testis |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-101 | Sentence | denotes | Testis-specific sulfoglycolipid, seminolipid, is essential for germ cell function in spermatogenesis. |
TextSentencer_T2 | 102-215 | Sentence | denotes | More than 90% of the glycolipid in mammalian testis consists of a unique sulfated glyceroglycolipid, seminolipid. |
TextSentencer_T3 | 216-343 | Sentence | denotes | The sulfation of the molecule is catalyzed by a Golgi membrane-associated sulfotransferase, cerebroside sulfotransferase (CST). |
TextSentencer_T4 | 344-488 | Sentence | denotes | Disruption of the Cst gene in mice results in male infertility due to the arrest of spermatogenesis prior to the metaphase of the first meiosis. |
TextSentencer_T5 | 489-624 | Sentence | denotes | However, the issue of which side of the cell function-germ cells or Sertoli cells-is deteriorated in this mutant mouse remains unknown. |
TextSentencer_T6 | 625-866 | Sentence | denotes | Our findings show that the defect is in the germ cell side, as evidenced by a transplantation analysis, in which wild-type spermatogonia expressing the green fluorescent protein were injected into the seminiferous tubules of CST-null testis. |
TextSentencer_T7 | 867-986 | Sentence | denotes | The transplanted GFP-positive cells generated colonies and spermatogenesis proceeded over meiosis in the mutant testis. |
TextSentencer_T8 | 987-1389 | Sentence | denotes | The findings also clearly show that the seminolipid is expressed on the plasma membranes of spermatogonia, spermatocytes, spermatids, and spermatozoa, as evidenced by the immunostaining of wild-type testes using an anti-sulfogalactolipid antibody, Sulph-1 in comparison with CST-null testes as a negative control, and that seminolipid appears as early as day 8 of age, when Type B spermatogonia emerge. |
T1 | 0-101 | Sentence | denotes | Testis-specific sulfoglycolipid, seminolipid, is essential for germ cell function in spermatogenesis. |
T2 | 102-215 | Sentence | denotes | More than 90% of the glycolipid in mammalian testis consists of a unique sulfated glyceroglycolipid, seminolipid. |
T3 | 216-343 | Sentence | denotes | The sulfation of the molecule is catalyzed by a Golgi membrane-associated sulfotransferase, cerebroside sulfotransferase (CST). |
T4 | 344-488 | Sentence | denotes | Disruption of the Cst gene in mice results in male infertility due to the arrest of spermatogenesis prior to the metaphase of the first meiosis. |
T5 | 489-624 | Sentence | denotes | However, the issue of which side of the cell function-germ cells or Sertoli cells-is deteriorated in this mutant mouse remains unknown. |
T6 | 625-866 | Sentence | denotes | Our findings show that the defect is in the germ cell side, as evidenced by a transplantation analysis, in which wild-type spermatogonia expressing the green fluorescent protein were injected into the seminiferous tubules of CST-null testis. |
T7 | 867-986 | Sentence | denotes | The transplanted GFP-positive cells generated colonies and spermatogenesis proceeded over meiosis in the mutant testis. |
T8 | 987-1389 | Sentence | denotes | The findings also clearly show that the seminolipid is expressed on the plasma membranes of spermatogonia, spermatocytes, spermatids, and spermatozoa, as evidenced by the immunostaining of wild-type testes using an anti-sulfogalactolipid antibody, Sulph-1 in comparison with CST-null testes as a negative control, and that seminolipid appears as early as day 8 of age, when Type B spermatogonia emerge. |
T1 | 0-101 | Sentence | denotes | Testis-specific sulfoglycolipid, seminolipid, is essential for germ cell function in spermatogenesis. |
T2 | 102-215 | Sentence | denotes | More than 90% of the glycolipid in mammalian testis consists of a unique sulfated glyceroglycolipid, seminolipid. |
T3 | 216-343 | Sentence | denotes | The sulfation of the molecule is catalyzed by a Golgi membrane-associated sulfotransferase, cerebroside sulfotransferase (CST). |
T4 | 344-488 | Sentence | denotes | Disruption of the Cst gene in mice results in male infertility due to the arrest of spermatogenesis prior to the metaphase of the first meiosis. |
T5 | 489-624 | Sentence | denotes | However, the issue of which side of the cell function-germ cells or Sertoli cells-is deteriorated in this mutant mouse remains unknown. |
T6 | 625-866 | Sentence | denotes | Our findings show that the defect is in the germ cell side, as evidenced by a transplantation analysis, in which wild-type spermatogonia expressing the green fluorescent protein were injected into the seminiferous tubules of CST-null testis. |
T7 | 867-986 | Sentence | denotes | The transplanted GFP-positive cells generated colonies and spermatogenesis proceeded over meiosis in the mutant testis. |
T8 | 987-1389 | Sentence | denotes | The findings also clearly show that the seminolipid is expressed on the plasma membranes of spermatogonia, spermatocytes, spermatids, and spermatozoa, as evidenced by the immunostaining of wild-type testes using an anti-sulfogalactolipid antibody, Sulph-1 in comparison with CST-null testes as a negative control, and that seminolipid appears as early as day 8 of age, when Type B spermatogonia emerge. |
GlycoBiology-Epitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoEpitope-B_T1 | 1235-1242 | http://www.glycoepitope.jp/epitopes/AN0216 | denotes | Sulph-1 |
performance-test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-UBERON-AE-B_T1 | 0-6 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | Testis |
PD-UBERON-AE-B_T2 | 147-153 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
PD-UBERON-AE-B_T3 | 859-865 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
PD-UBERON-AE-B_T4 | 979-985 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testis |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 390-406 | Disease | denotes | male infertility | http://purl.obolibrary.org/obo/MONDO_0005372 |
T2 | 418-443 | Disease | denotes | arrest of spermatogenesis | http://purl.obolibrary.org/obo/MONDO_0010052 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 374-378 | OrganismTaxon | denotes | mice | 10088 |
T2 | 602-607 | OrganismTaxon | denotes | mouse | 10088|10090 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 0-6 | Body_part | denotes | Testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
T2 | 63-72 | Body_part | denotes | germ cell | http://purl.obolibrary.org/obo/CL_0000586 |
T3 | 147-153 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
T4 | 264-278 | Body_part | denotes | Golgi membrane | http://purl.obolibrary.org/obo/GO_0000139 |
T5 | 543-553 | Body_part | denotes | germ cells | http://purl.obolibrary.org/obo/CL_0000586 |
T6 | 557-570 | Body_part | denotes | Sertoli cells | http://purl.obolibrary.org/obo/CL_0000216 |
T7 | 669-678 | Body_part | denotes | germ cell | http://purl.obolibrary.org/obo/CL_0000586 |
T8 | 826-846 | Body_part | denotes | seminiferous tubules | http://purl.obolibrary.org/obo/UBERON_0001343 |
T9 | 859-865 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
T10 | 979-985 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/UBERON_0000473 |
T11 | 1059-1075 | Body_part | denotes | plasma membranes | http://purl.obolibrary.org/obo/GO_0005886 |
T12 | 1094-1107 | Body_part | denotes | spermatocytes | http://purl.obolibrary.org/obo/CL_0000017 |
T13 | 1109-1119 | Body_part | denotes | spermatids | http://purl.obolibrary.org/obo/CL_0000018 |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 0-6 | Body_part | denotes | Testis | http://purl.obolibrary.org/obo/MAT_0000132 |
T2 | 63-72 | Body_part | denotes | germ cell | http://purl.obolibrary.org/obo/MAT_0000334 |
T3 | 147-153 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/MAT_0000132 |
T4 | 390-394 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
T5 | 543-553 | Body_part | denotes | germ cells | http://purl.obolibrary.org/obo/MAT_0000334 |
T6 | 669-678 | Body_part | denotes | germ cell | http://purl.obolibrary.org/obo/MAT_0000334 |
T7 | 826-846 | Body_part | denotes | seminiferous tubules | http://purl.obolibrary.org/obo/MAT_0000503 |
T8 | 859-865 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/MAT_0000132 |
T9 | 979-985 | Body_part | denotes | testis | http://purl.obolibrary.org/obo/MAT_0000132 |
HP-phenotype
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 390-406 | Phenotype | denotes | male infertility | HP:0003251 |
CL-cell
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 63-72 | Cell | denotes | germ cell | http://purl.obolibrary.org/obo/CL:0000586 |
T2 | 543-553 | Cell | denotes | germ cells | http://purl.obolibrary.org/obo/CL:0000586 |
T3 | 557-570 | Cell | denotes | Sertoli cells | http://purl.obolibrary.org/obo/CL:0000216 |
T4 | 669-678 | Cell | denotes | germ cell | http://purl.obolibrary.org/obo/CL:0000586 |
T5 | 1094-1107 | Cell | denotes | spermatocytes | http://purl.obolibrary.org/obo/CL:0000017 |
T6 | 1109-1119 | Cell | denotes | spermatids | http://purl.obolibrary.org/obo/CL:0000018 |