PubMed:15632136
Annnotations
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | https://acgg.asia/db/ggdb/info/gg229 | denotes | GPI7 |
| T2 | 30-35 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T3 | 611-615 | https://acgg.asia/db/ggdb/info/gg229 | denotes | GPI7 |
| T4 | 827-832 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T5 | 1069-1074 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T6 | 1116-1121 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T7 | 1154-1159 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T8 | 1335-1340 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T9 | 1547-1552 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T10 | 1591-1596 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | https://acgg.asia/db/ggdb/info/gg229 | denotes | GPI7 |
| T2 | 30-35 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T3 | 611-615 | https://acgg.asia/db/ggdb/info/gg229 | denotes | GPI7 |
| T4 | 827-832 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T5 | 1069-1074 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| T6 | 1116-1121 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T7 | 1154-1159 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T8 | 1335-1340 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T9 | 1547-1552 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| T10 | 1591-1596 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 469-476 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T2 | 666-673 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T3 | 1205-1212 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T4 | 1410-1417 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-97 | Sentence | denotes | GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol. |
| T2 | 98-204 | Sentence | denotes | Many eukaryotic cell surface proteins are anchored to the membrane via glycosylphosphatidylinositol (GPI). |
| T3 | 205-313 | Sentence | denotes | GPI is synthesized from phosphatidylinositol by stepwise reactions and attached en bloc to nascent proteins. |
| T4 | 314-393 | Sentence | denotes | In mammalian cells, the major GPI species transferred to proteins is termed H7. |
| T5 | 394-604 | Sentence | denotes | By attachment of an additional ethanolamine phosphate (EtNP) to the second mannose, H7 can be converted to H8, which acts as a minor type of protein-linked GPI and also exists as a free GPI on the cell surface. |
| T6 | 605-741 | Sentence | denotes | Yeast GPI7 is involved in the transfer of EtNP to the second mannose, but the corresponding mammalian enzyme has not yet been clarified. |
| T7 | 742-876 | Sentence | denotes | Here, we report that the human homolog of Gpi7p (hGPI7) forms a protein complex with PIG-F and is involved in the H7-to-H8 conversion. |
| T8 | 877-978 | Sentence | denotes | We knocked down hGPI7 by RNA interference and found that H7 accumulated with little production of H8. |
| T9 | 979-1153 | Sentence | denotes | Immunoprecipitation experiments revealed that hGPI7 was associated with and stabilized by PIG-F, which is known to bind to and stabilize PIG-O, a protein homologous to hGPI7. |
| T10 | 1154-1261 | Sentence | denotes | PIG-O is a transferase that adds EtNP to the third mannose, rendering GPI capable of attaching to proteins. |
| T11 | 1262-1418 | Sentence | denotes | We further found that the overexpression of hGPI7 decreased the level of PIG-O and, therefore, decreased the level of EtNP transferred to the third mannose. |
| T12 | 1419-1597 | Sentence | denotes | Finally, we propose a mechanism for the regulation of GPI biosynthesis through competition between the two independent enzymes, PIG-O and hGPI7, for the common stabilizer, PIG-F. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 469-476 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T2 | 666-673 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T3 | 1205-1212 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T4 | 1410-1417 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 30-35 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| PD-GlycoGenes20190927-B_T2 | 714-717 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T3 | 827-832 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| PD-GlycoGenes20190927-B_T4 | 1069-1074 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
| PD-GlycoGenes20190927-B_T5 | 1116-1121 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| PD-GlycoGenes20190927-B_T6 | 1154-1159 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| PD-GlycoGenes20190927-B_T7 | 1335-1340 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| PD-GlycoGenes20190927-B_T8 | 1547-1552 | https://acgg.asia/db/ggdb/info/gg227 | denotes | PIG-O |
| PD-GlycoGenes20190927-B_T9 | 1591-1596 | https://acgg.asia/db/ggdb/info/gg228 | denotes | PIG-F |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 767-772 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 103-118 | Body_part | denotes | eukaryotic cell | http://purl.obolibrary.org/obo/CL_0000255 |
| T2 | 156-164 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
Glycosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 103-118 | Cell | denotes | eukaryotic cell | http://purl.obolibrary.org/obo/CL:0000255 |