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PubMed:15604091 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 719-737 https://glytoucan.org/Structures/Glycans/G08371CD denotes sialyl-Tn antigens
T2 719-737 https://glytoucan.org/Structures/Glycans/G36123IU denotes sialyl-Tn antigens
T3 747-756 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T4 806-815 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T5 976-994 https://glytoucan.org/Structures/Glycans/G08371CD denotes sialyl-Tn antigens
T6 976-994 https://glytoucan.org/Structures/Glycans/G36123IU denotes sialyl-Tn antigens
T7 1116-1125 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T8 1426-1435 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 719-737 Glycan_Motif denotes sialyl-Tn antigens https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G36123IU|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G08371CD
T3 747-756 Glycan_Motif denotes T antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T4 806-815 Glycan_Motif denotes T antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T5 976-994 Glycan_Motif denotes sialyl-Tn antigens https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G36123IU|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G08371CD
T7 1116-1125 Glycan_Motif denotes T antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T8 1426-1435 Glycan_Motif denotes T antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 747-756 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
T2 806-815 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
T3 1116-1125 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
T4 1426-1435 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
TextSentencer_T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
TextSentencer_T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
TextSentencer_T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
TextSentencer_T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
TextSentencer_T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
TextSentencer_T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
TextSentencer_T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
TextSentencer_T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.
T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.
T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 719-737 https://glytoucan.org/Structures/Glycans/G08371CD denotes sialyl-Tn antigens
T2 719-737 https://glytoucan.org/Structures/Glycans/G36123IU denotes sialyl-Tn antigens
T3 747-756 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T4 806-815 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T5 976-994 https://glytoucan.org/Structures/Glycans/G08371CD denotes sialyl-Tn antigens
T6 976-994 https://glytoucan.org/Structures/Glycans/G36123IU denotes sialyl-Tn antigens
T7 1116-1125 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T8 1426-1435 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen

uniprot-human

Id Subject Object Predicate Lexical cue
T1 81-85 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T2 352-356 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T3 450-454 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T4 615-619 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T5 892-896 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T6 1233-1237 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T7 267-292 http://www.uniprot.org/uniprot/Q08380 denotes tumor-associated antigens
T8 267-292 http://www.uniprot.org/uniprot/P30408 denotes tumor-associated antigens

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 51-61 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinomas
T2 97-109 http://purl.bioontology.org/ontology/NCBITAXON/991903 denotes polymorphism
T3 97-109 http://purl.bioontology.org/ontology/NCBITAXON/60540 denotes polymorphism
T4 111-119 http://purl.bioontology.org/ontology/NCBITAXON/317910 denotes Aberrant
T5 318-330 http://purl.bioontology.org/ontology/NCBITAXON/60540 denotes polymorphism
T6 318-330 http://purl.bioontology.org/ontology/NCBITAXON/991903 denotes polymorphism
T7 400-410 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinomas
T8 566-575 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T9 673-683 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinomas
T10 852-862 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinomas
T11 1049-1058 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T12 1213-1225 http://purl.bioontology.org/ontology/NCBITAXON/60540 denotes polymorphism
T13 1213-1225 http://purl.bioontology.org/ontology/NCBITAXON/991903 denotes polymorphism
T14 1298-1304 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T15 1305-1310 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 120-133 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T2 304-310 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T3 719-725 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T4 976-982 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T5 1384-1391 http://purl.obolibrary.org/obo/GO_0032502 denotes develop
T6 1397-1407 http://purl.obolibrary.org/obo/GO_0002118 denotes aggressive

GO-CC

Id Subject Object Predicate Lexical cue
T1 576-580 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 1059-1063 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1305-1310 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 21-28 http://edamontology.org/topic_2830 denotes antigen
T2 92-96 http://edamontology.org/topic_2885 denotes VNTR
T3 92-96 http://edamontology.org/topic_2867 denotes VNTR
T4 97-109 http://edamontology.org/topic_0199 denotes polymorphism
T5 284-292 http://edamontology.org/topic_2830 denotes antigens
T6 318-330 http://edamontology.org/topic_0199 denotes polymorphism
T7 520-532 http://edamontology.org/topic_0152 denotes carbohydrate
T8 533-541 http://edamontology.org/topic_2830 denotes antigens
T9 729-737 http://edamontology.org/topic_2830 denotes antigens
T10 749-756 http://edamontology.org/topic_2830 denotes antigen
T11 777-802 http://edamontology.org/topic_0203 denotes expressed. The expression
T12 808-815 http://edamontology.org/topic_2830 denotes antigen
T13 986-994 http://edamontology.org/topic_2830 denotes antigens
T14 1118-1125 http://edamontology.org/topic_2830 denotes antigen
T15 1173-1177 http://edamontology.org/topic_2885 denotes VNTR
T16 1173-1177 http://edamontology.org/topic_2867 denotes VNTR
T17 1213-1225 http://edamontology.org/topic_0199 denotes polymorphism
T18 1298-1304 http://edamontology.org/topic_2640 denotes cancer
T19 1428-1435 http://edamontology.org/topic_2830 denotes antigen

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 620-630 http://edamontology.org/operation_3429 denotes constructs
T2 1130-1138 http://edamontology.org/operation_2423 denotes detected

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
15604091-8#46#50#gene4582 1233-1237 gene4582 denotes MUC1
15604091-8#103#117#diseaseC0024623 1290-1304 diseaseC0024623 denotes gastric cancer
15604091-8#103#117#diseaseC0699791 1290-1304 diseaseC0699791 denotes gastric cancer
46#50#gene4582103#117#diseaseC0024623 15604091-8#46#50#gene4582 15604091-8#103#117#diseaseC0024623 associated_with MUC1,gastric cancer
46#50#gene4582103#117#diseaseC0699791 15604091-8#46#50#gene4582 15604091-8#103#117#diseaseC0699791 associated_with MUC1,gastric cancer

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 296-298 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T2 311-313 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T3 712-714 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T4 726-728 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T5 969-971 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T6 983-985 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 747-756 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
PD-GlycoEpitope-B_T2 806-815 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
PD-GlycoEpitope-B_T3 1116-1125 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
PD-GlycoEpitope-B_T4 1426-1435 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
PD-GlycoEpitope-B_T5 726-737 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigens
PD-GlycoEpitope-B_T6 983-994 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigens
PD-GlycoEpitope-B_T7 719-737 http://www.glycoepitope.jp/epitopes/EP0022 denotes sialyl-Tn antigens
PD-GlycoEpitope-B_T8 976-994 http://www.glycoepitope.jp/epitopes/EP0022 denotes sialyl-Tn antigens

DisGeNET

Id Subject Object Predicate Lexical cue
T0 81-85 gene:4582 denotes MUC1
T1 51-61 disease:C0007097 denotes carcinomas
T2 892-896 gene:4582 denotes MUC1
T3 852-862 disease:C0007097 denotes carcinomas
T4 1233-1237 gene:4582 denotes MUC1
T5 1290-1304 disease:C0024623 denotes gastric cancer
T6 1233-1237 gene:4582 denotes MUC1
T7 1290-1304 disease:C0699791 denotes gastric cancer
R1 T0 T1 associated_with MUC1,carcinomas
R2 T2 T3 associated_with MUC1,carcinomas
R3 T4 T5 associated_with MUC1,gastric cancer
R4 T6 T7 associated_with MUC1,gastric cancer

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 51-61 Phenotype denotes carcinomas HP:0030731
T2 267-272 Phenotype denotes tumor HP:0002664
T3 400-410 Phenotype denotes carcinomas HP:0030731
T4 503-508 Phenotype denotes tumor HP:0002664
T5 566-575 Phenotype denotes carcinoma HP:0030731
T6 673-683 Phenotype denotes carcinomas HP:0030731
T7 852-862 Phenotype denotes carcinomas HP:0030731
T8 1049-1058 Phenotype denotes carcinoma HP:0030731
T9 1290-1304 Phenotype denotes gastric cancer HP:0012126
T10 1397-1407 Phenotype denotes aggressive HP:0000718

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 43-61 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T2 267-272 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 392-410 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T4 503-508 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T5 558-575 Disease denotes gastric carcinoma http://purl.obolibrary.org/obo/MONDO_0004950
T6 665-683 Disease denotes Gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T7 844-862 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T8 1041-1058 Disease denotes gastric carcinoma http://purl.obolibrary.org/obo/MONDO_0004950
T9 1290-1304 Disease denotes gastric cancer http://purl.obolibrary.org/obo/MONDO_0001056
T10 1408-1414 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 747-756 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T2 806-815 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T3 1116-1125 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T4 1426-1435 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 747-756 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T2 806-815 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T3 1116-1125 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T4 1426-1435 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 51-61 Phenotype denotes carcinomas HP:0030731
T2 267-272 Phenotype denotes tumor HP:0002664
T3 400-410 Phenotype denotes carcinomas HP:0030731
T4 503-508 Phenotype denotes tumor HP:0002664
T5 566-575 Phenotype denotes carcinoma HP:0030731
T6 673-683 Phenotype denotes carcinomas HP:0030731
T7 852-862 Phenotype denotes carcinomas HP:0030731
T8 1049-1058 Phenotype denotes carcinoma HP:0030731
T9 1290-1304 Phenotype denotes gastric cancer HP:0012126

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 43-61 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T2 267-272 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 392-410 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T4 503-508 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T5 558-575 Disease denotes gastric carcinoma http://purl.obolibrary.org/obo/MONDO_0004950
T6 665-683 Disease denotes Gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T7 844-862 Disease denotes gastric carcinomas http://purl.obolibrary.org/obo/MONDO_0004950
T8 1041-1058 Disease denotes gastric carcinoma http://purl.obolibrary.org/obo/MONDO_0004950
T9 1290-1304 Disease denotes gastric cancer http://purl.obolibrary.org/obo/MONDO_0001056
T10 1408-1414 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1298-1310 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
TextSentencer_T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
TextSentencer_T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
TextSentencer_T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
TextSentencer_T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
TextSentencer_T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
TextSentencer_T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
TextSentencer_T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
TextSentencer_T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.
T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.
T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-110 Sentence denotes Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism.
T2 111-208 Sentence denotes Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation.
T3 209-411 Sentence denotes We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas.
T4 412-664 Sentence denotes We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats.
T5 665-787 Sentence denotes Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed.
T6 788-925 Sentence denotes The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles.
T7 926-995 Sentence denotes No significant associations were found for Tn and sialyl-Tn antigens.
T8 996-1186 Sentence denotes This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions.
T9 1187-1436 Sentence denotes Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 747-756 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T2 806-815 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T3 1116-1125 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T4 1426-1435 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 747-756 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T2 806-815 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T3 1116-1125 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T4 1426-1435 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1298-1310 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064