PubMed:15604091
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 719-737 | https://glytoucan.org/Structures/Glycans/G08371CD | denotes | sialyl-Tn antigens |
| T2 | 719-737 | https://glytoucan.org/Structures/Glycans/G36123IU | denotes | sialyl-Tn antigens |
| T3 | 747-756 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T4 | 806-815 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T5 | 976-994 | https://glytoucan.org/Structures/Glycans/G08371CD | denotes | sialyl-Tn antigens |
| T6 | 976-994 | https://glytoucan.org/Structures/Glycans/G36123IU | denotes | sialyl-Tn antigens |
| T7 | 1116-1125 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T8 | 1426-1435 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 719-737 | Glycan_Motif | denotes | sialyl-Tn antigens | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G36123IU|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G08371CD |
| T3 | 747-756 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T4 | 806-815 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T5 | 976-994 | Glycan_Motif | denotes | sialyl-Tn antigens | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G36123IU|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G08371CD |
| T7 | 1116-1125 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T8 | 1426-1435 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 747-756 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| T2 | 806-815 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| T3 | 1116-1125 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| T4 | 1426-1435 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-110 | Sentence | denotes | Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. |
| TextSentencer_T2 | 111-208 | Sentence | denotes | Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation. |
| TextSentencer_T3 | 209-411 | Sentence | denotes | We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas. |
| TextSentencer_T4 | 412-664 | Sentence | denotes | We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats. |
| TextSentencer_T5 | 665-787 | Sentence | denotes | Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed. |
| TextSentencer_T6 | 788-925 | Sentence | denotes | The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles. |
| TextSentencer_T7 | 926-995 | Sentence | denotes | No significant associations were found for Tn and sialyl-Tn antigens. |
| TextSentencer_T8 | 996-1186 | Sentence | denotes | This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions. |
| TextSentencer_T9 | 1187-1436 | Sentence | denotes | Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen. |
| T1 | 0-110 | Sentence | denotes | Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. |
| T2 | 111-208 | Sentence | denotes | Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation. |
| T3 | 209-411 | Sentence | denotes | We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas. |
| T4 | 412-664 | Sentence | denotes | We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats. |
| T5 | 665-787 | Sentence | denotes | Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed. |
| T6 | 788-925 | Sentence | denotes | The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles. |
| T7 | 926-995 | Sentence | denotes | No significant associations were found for Tn and sialyl-Tn antigens. |
| T8 | 996-1186 | Sentence | denotes | This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions. |
| T9 | 1187-1436 | Sentence | denotes | Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen. |
| T1 | 0-110 | Sentence | denotes | Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. |
| T2 | 111-208 | Sentence | denotes | Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation. |
| T3 | 209-411 | Sentence | denotes | We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas. |
| T4 | 412-664 | Sentence | denotes | We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats. |
| T5 | 665-787 | Sentence | denotes | Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed. |
| T6 | 788-925 | Sentence | denotes | The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles. |
| T7 | 926-995 | Sentence | denotes | No significant associations were found for Tn and sialyl-Tn antigens. |
| T8 | 996-1186 | Sentence | denotes | This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions. |
| T9 | 1187-1436 | Sentence | denotes | Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 719-737 | https://glytoucan.org/Structures/Glycans/G08371CD | denotes | sialyl-Tn antigens |
| T2 | 719-737 | https://glytoucan.org/Structures/Glycans/G36123IU | denotes | sialyl-Tn antigens |
| T3 | 747-756 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T4 | 806-815 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T5 | 976-994 | https://glytoucan.org/Structures/Glycans/G08371CD | denotes | sialyl-Tn antigens |
| T6 | 976-994 | https://glytoucan.org/Structures/Glycans/G36123IU | denotes | sialyl-Tn antigens |
| T7 | 1116-1125 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
| T8 | 1426-1435 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 81-85 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T2 | 352-356 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T3 | 450-454 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T4 | 615-619 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T5 | 892-896 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T6 | 1233-1237 | http://www.uniprot.org/uniprot/Q9BXA4 | denotes | MUC1 |
| T7 | 267-292 | http://www.uniprot.org/uniprot/Q08380 | denotes | tumor-associated antigens |
| T8 | 267-292 | http://www.uniprot.org/uniprot/P30408 | denotes | tumor-associated antigens |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 51-61 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinomas |
| T2 | 97-109 | http://purl.bioontology.org/ontology/NCBITAXON/991903 | denotes | polymorphism |
| T3 | 97-109 | http://purl.bioontology.org/ontology/NCBITAXON/60540 | denotes | polymorphism |
| T4 | 111-119 | http://purl.bioontology.org/ontology/NCBITAXON/317910 | denotes | Aberrant |
| T5 | 318-330 | http://purl.bioontology.org/ontology/NCBITAXON/60540 | denotes | polymorphism |
| T6 | 318-330 | http://purl.bioontology.org/ontology/NCBITAXON/991903 | denotes | polymorphism |
| T7 | 400-410 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinomas |
| T8 | 566-575 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinoma |
| T9 | 673-683 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinomas |
| T10 | 852-862 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinomas |
| T11 | 1049-1058 | http://purl.bioontology.org/ontology/NCBITAXON/166034 | denotes | carcinoma |
| T12 | 1213-1225 | http://purl.bioontology.org/ontology/NCBITAXON/60540 | denotes | polymorphism |
| T13 | 1213-1225 | http://purl.bioontology.org/ontology/NCBITAXON/991903 | denotes | polymorphism |
| T14 | 1298-1304 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
| T15 | 1305-1310 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 120-133 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T2 | 304-310 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
| T3 | 719-725 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
| T4 | 976-982 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
| T5 | 1384-1391 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | develop |
| T6 | 1397-1407 | http://purl.obolibrary.org/obo/GO_0002118 | denotes | aggressive |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 576-580 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 1059-1063 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 1305-1310 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 21-28 | http://edamontology.org/topic_2830 | denotes | antigen |
| T2 | 92-96 | http://edamontology.org/topic_2885 | denotes | VNTR |
| T3 | 92-96 | http://edamontology.org/topic_2867 | denotes | VNTR |
| T4 | 97-109 | http://edamontology.org/topic_0199 | denotes | polymorphism |
| T5 | 284-292 | http://edamontology.org/topic_2830 | denotes | antigens |
| T6 | 318-330 | http://edamontology.org/topic_0199 | denotes | polymorphism |
| T7 | 520-532 | http://edamontology.org/topic_0152 | denotes | carbohydrate |
| T8 | 533-541 | http://edamontology.org/topic_2830 | denotes | antigens |
| T9 | 729-737 | http://edamontology.org/topic_2830 | denotes | antigens |
| T10 | 749-756 | http://edamontology.org/topic_2830 | denotes | antigen |
| T11 | 777-802 | http://edamontology.org/topic_0203 | denotes | expressed. The expression |
| T12 | 808-815 | http://edamontology.org/topic_2830 | denotes | antigen |
| T13 | 986-994 | http://edamontology.org/topic_2830 | denotes | antigens |
| T14 | 1118-1125 | http://edamontology.org/topic_2830 | denotes | antigen |
| T15 | 1173-1177 | http://edamontology.org/topic_2885 | denotes | VNTR |
| T16 | 1173-1177 | http://edamontology.org/topic_2867 | denotes | VNTR |
| T17 | 1213-1225 | http://edamontology.org/topic_0199 | denotes | polymorphism |
| T18 | 1298-1304 | http://edamontology.org/topic_2640 | denotes | cancer |
| T19 | 1428-1435 | http://edamontology.org/topic_2830 | denotes | antigen |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 620-630 | http://edamontology.org/operation_3429 | denotes | constructs |
| T2 | 1130-1138 | http://edamontology.org/operation_2423 | denotes | detected |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 15604091-8#46#50#gene4582 | 1233-1237 | gene4582 | denotes | MUC1 |
| 15604091-8#103#117#diseaseC0024623 | 1290-1304 | diseaseC0024623 | denotes | gastric cancer |
| 15604091-8#103#117#diseaseC0699791 | 1290-1304 | diseaseC0699791 | denotes | gastric cancer |
| 46#50#gene4582103#117#diseaseC0024623 | 15604091-8#46#50#gene4582 | 15604091-8#103#117#diseaseC0024623 | associated_with | MUC1,gastric cancer |
| 46#50#gene4582103#117#diseaseC0699791 | 15604091-8#46#50#gene4582 | 15604091-8#103#117#diseaseC0699791 | associated_with | MUC1,gastric cancer |
Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| Lectin_T1 | 296-298 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
| Lectin_T2 | 311-313 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
| Lectin_T3 | 712-714 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
| Lectin_T4 | 726-728 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
| Lectin_T5 | 969-971 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
| Lectin_T6 | 983-985 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 747-756 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| PD-GlycoEpitope-B_T2 | 806-815 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| PD-GlycoEpitope-B_T3 | 1116-1125 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| PD-GlycoEpitope-B_T4 | 1426-1435 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
| PD-GlycoEpitope-B_T5 | 726-737 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigens |
| PD-GlycoEpitope-B_T6 | 983-994 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigens |
| PD-GlycoEpitope-B_T7 | 719-737 | http://www.glycoepitope.jp/epitopes/EP0022 | denotes | sialyl-Tn antigens |
| PD-GlycoEpitope-B_T8 | 976-994 | http://www.glycoepitope.jp/epitopes/EP0022 | denotes | sialyl-Tn antigens |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 81-85 | gene:4582 | denotes | MUC1 |
| T1 | 51-61 | disease:C0007097 | denotes | carcinomas |
| T2 | 892-896 | gene:4582 | denotes | MUC1 |
| T3 | 852-862 | disease:C0007097 | denotes | carcinomas |
| T4 | 1233-1237 | gene:4582 | denotes | MUC1 |
| T5 | 1290-1304 | disease:C0024623 | denotes | gastric cancer |
| T6 | 1233-1237 | gene:4582 | denotes | MUC1 |
| T7 | 1290-1304 | disease:C0699791 | denotes | gastric cancer |
| R1 | T0 | T1 | associated_with | MUC1,carcinomas |
| R2 | T2 | T3 | associated_with | MUC1,carcinomas |
| R3 | T4 | T5 | associated_with | MUC1,gastric cancer |
| R4 | T6 | T7 | associated_with | MUC1,gastric cancer |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 51-61 | Phenotype | denotes | carcinomas | HP:0030731 |
| T2 | 267-272 | Phenotype | denotes | tumor | HP:0002664 |
| T3 | 400-410 | Phenotype | denotes | carcinomas | HP:0030731 |
| T4 | 503-508 | Phenotype | denotes | tumor | HP:0002664 |
| T5 | 566-575 | Phenotype | denotes | carcinoma | HP:0030731 |
| T6 | 673-683 | Phenotype | denotes | carcinomas | HP:0030731 |
| T7 | 852-862 | Phenotype | denotes | carcinomas | HP:0030731 |
| T8 | 1049-1058 | Phenotype | denotes | carcinoma | HP:0030731 |
| T9 | 1290-1304 | Phenotype | denotes | gastric cancer | HP:0012126 |
| T10 | 1397-1407 | Phenotype | denotes | aggressive | HP:0000718 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 43-61 | Disease | denotes | gastric carcinomas | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T2 | 267-272 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T3 | 392-410 | Disease | denotes | gastric carcinomas | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T4 | 503-508 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T5 | 558-575 | Disease | denotes | gastric carcinoma | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T6 | 665-683 | Disease | denotes | Gastric carcinomas | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T7 | 844-862 | Disease | denotes | gastric carcinomas | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T8 | 1041-1058 | Disease | denotes | gastric carcinoma | http://purl.obolibrary.org/obo/MONDO_0004950 |
| T9 | 1290-1304 | Disease | denotes | gastric cancer | http://purl.obolibrary.org/obo/MONDO_0001056 |
| T10 | 1408-1414 | Disease | denotes | tumors | http://purl.obolibrary.org/obo/MONDO_0005070 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 747-756 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T2 | 806-815 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T3 | 1116-1125 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T4 | 1426-1435 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 747-756 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T2 | 806-815 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T3 | 1116-1125 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T4 | 1426-1435 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 51-61 | Phenotype | denotes | carcinomas | HP:0030731 |
| T2 | 267-272 | Phenotype | denotes | tumor | HP:0002664 |
| T3 | 400-410 | Phenotype | denotes | carcinomas | HP:0030731 |
| T4 | 503-508 | Phenotype | denotes | tumor | HP:0002664 |
| T5 | 566-575 | Phenotype | denotes | carcinoma | HP:0030731 |
| T6 | 673-683 | Phenotype | denotes | carcinomas | HP:0030731 |
| T7 | 852-862 | Phenotype | denotes | carcinomas | HP:0030731 |
| T8 | 1049-1058 | Phenotype | denotes | carcinoma | HP:0030731 |
| T9 | 1290-1304 | Phenotype | denotes | gastric cancer | HP:0012126 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 719-737 | Glycan | denotes | sialyl-Tn antigens | https://api.glycosmos.org/wurcs2image/latest/png/binary/G36123IU |
| T2 | 747-756 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T3 | 806-815 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T4 | 976-994 | Glycan | denotes | sialyl-Tn antigens | https://api.glycosmos.org/wurcs2image/latest/png/binary/G36123IU |
| T5 | 1116-1125 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T6 | 1426-1435 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1298-1310 | Cell | denotes | cancer cells | http://purl.obolibrary.org/obo/CL:0001064 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 43-61 | Disease | denotes | gastric carcinomas | MONDO:0004950 |
| T2 | 267-272 | Disease | denotes | tumor | MONDO:0005070 |
| T3 | 392-410 | Disease | denotes | gastric carcinomas | MONDO:0004950 |
| T4 | 503-508 | Disease | denotes | tumor | MONDO:0005070 |
| T5 | 558-575 | Disease | denotes | gastric carcinoma | MONDO:0004950 |
| T6 | 665-683 | Disease | denotes | Gastric carcinomas | MONDO:0004950 |
| T7 | 844-862 | Disease | denotes | gastric carcinomas | MONDO:0004950 |
| T8 | 1041-1058 | Disease | denotes | gastric carcinoma | MONDO:0004950 |
| T9 | 1290-1304 | Disease | denotes | gastric cancer | MONDO:0001056|MONDO:0004950 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 868-876 | Organism | denotes | patients | 9606 |
| T2 | 1370-1378 | Organism | denotes | patients | 9606 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-110 | Sentence | denotes | Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. |
| T2 | 111-208 | Sentence | denotes | Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transformation. |
| T3 | 209-411 | Sentence | denotes | We investigated the association between expression of the tumor-associated antigens T, Tn, and sialyl-Tn and polymorphism in the length of the MUC1 mucin tandem repeat in a series of gastric carcinomas. |
| T4 | 412-664 | Sentence | denotes | We further evaluated the relevance of MUC1 tandem repeat length on the expression of these tumor-associated carbohydrate antigens (TACAs) using a gastric carcinoma cell line model expressing recombinant MUC1 constructs carrying 0, 3, 9, and 42 repeats. |
| T5 | 665-787 | Sentence | denotes | Gastric carcinomas showed a high prevalence of Tn and sialyl-Tn antigens, whereas T antigen was less frequently expressed. |
| T6 | 788-925 | Sentence | denotes | The expression of T antigen was significantly higher in gastric carcinomas from patients homozygous for MUC1 large tandem repeat alleles. |
| T7 | 926-995 | Sentence | denotes | No significant associations were found for Tn and sialyl-Tn antigens. |
| T8 | 996-1186 | Sentence | denotes | This novel association was reinforced by the gastric carcinoma cell line model experiments, where de novo expression of T antigen was detected in clones transfected with larger VNTR regions. |
| T9 | 1187-1436 | Sentence | denotes | Our results indicate that polymorphism in the MUC1 tandem repeat influences the expression of TACAs in gastric cancer cells and may therefore allow the identification of subgroups of patients that develop more aggressive tumors expressing T antigen. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 747-756 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T2 | 806-815 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T3 | 1116-1125 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
| T4 | 1426-1435 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1298-1310 | Cell | denotes | cancer cells | http://purl.obolibrary.org/obo/CL:0001064 |