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sentences

Id Subject Object Predicate Lexical cue
T1 0-124 Sentence denotes The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
T2 125-284 Sentence denotes The promoter of the major histocompatibility class II gene DRA contains an octamer element (ATTTGCAT) that is required for efficient DRA expression in B cells.
T3 285-346 Sentence denotes Several DNA-binding proteins are known to bind this sequence.
T4 347-425 Sentence denotes The best characterized are the B cell-specific OTF-2 and the ubiquitous OTF-1.
T5 426-508 Sentence denotes This report directly demonstrates that OTF-2 but not OTF-1 regulates the DRA gene.
T6 509-687 Sentence denotes In vitro transcription analysis using protein fractions enriched for the octamer-binding protein OTF-2 demonstrate a positive functional role for OTF-2 in DRA gene transcription.
T7 688-840 Sentence denotes In contrast, OTF-1-enriched protein fractions did not affect DRA gene transcription although it functionally enhanced the transcription of another gene.
T8 841-965 Sentence denotes Recombinant OTF-2 protein produced by in vitro transcription/translation could also enhance DRA gene transcription in vitro.
T9 966-1180 Sentence denotes In vivo transient transfection studies utilizing an OTF-2 expression vector resulted in similar findings: that OTF-2 protein enhanced DRA gene transcription, and that this effect requires an intact octamer element.
T10 1181-1335 Sentence denotes Together these results constitute the first direct evidence of a positive role for the lymphoid-specific octamer-binding factor in DRA gene transcription.
T1 0-124 Sentence denotes The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
T2 125-284 Sentence denotes The promoter of the major histocompatibility class II gene DRA contains an octamer element (ATTTGCAT) that is required for efficient DRA expression in B cells.
T3 285-346 Sentence denotes Several DNA-binding proteins are known to bind this sequence.
T4 347-425 Sentence denotes The best characterized are the B cell-specific OTF-2 and the ubiquitous OTF-1.
T5 426-508 Sentence denotes This report directly demonstrates that OTF-2 but not OTF-1 regulates the DRA gene.
T6 509-687 Sentence denotes In vitro transcription analysis using protein fractions enriched for the octamer-binding protein OTF-2 demonstrate a positive functional role for OTF-2 in DRA gene transcription.
T7 688-840 Sentence denotes In contrast, OTF-1-enriched protein fractions did not affect DRA gene transcription although it functionally enhanced the transcription of another gene.
T8 841-965 Sentence denotes Recombinant OTF-2 protein produced by in vitro transcription/translation could also enhance DRA gene transcription in vitro.
T9 966-1180 Sentence denotes In vivo transient transfection studies utilizing an OTF-2 expression vector resulted in similar findings: that OTF-2 protein enhanced DRA gene transcription, and that this effect requires an intact octamer element.
T10 1181-1335 Sentence denotes Together these results constitute the first direct evidence of a positive role for the lymphoid-specific octamer-binding factor in DRA gene transcription.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-34 protein denotes B cell-specific nuclear factor
T2 35-40 protein denotes OTF-2
T3 83-118 DNA denotes human class II transplantation gene
T4 120-123 DNA denotes DRA
T5 145-183 DNA denotes major histocompatibility class II gene
T6 184-187 DNA denotes DRA
T7 200-215 DNA denotes octamer element
T8 258-261 DNA denotes DRA
T9 276-283 cell_type denotes B cells
T10 293-313 protein denotes DNA-binding proteins
T11 378-399 protein denotes B cell-specific OTF-2
T12 419-424 protein denotes OTF-1
T13 465-470 protein denotes OTF-2
T14 479-484 protein denotes OTF-1
T15 499-507 DNA denotes DRA gene
T16 606-611 protein denotes OTF-2
T17 655-660 protein denotes OTF-2
T18 664-672 DNA denotes DRA gene
T19 701-706 protein denotes OTF-1
T20 749-757 DNA denotes DRA gene
T21 841-866 protein denotes Recombinant OTF-2 protein
T22 933-941 DNA denotes DRA gene
T23 1018-1041 DNA denotes OTF-2 expression vector
T24 1077-1090 protein denotes OTF-2 protein
T25 1100-1108 DNA denotes DRA gene
T26 1164-1179 DNA denotes octamer element
T27 1268-1308 protein denotes lymphoid-specific octamer-binding factor

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-40 NP denotes The B cell-specific nuclear factor OTF-2
C3 79-118 NP denotes the human class II transplantation gene
C4 120-123 NP denotes DRA
C2 62-123 NP denotes transcription of the human class II transplantation gene, DRA
C5 141-187 NP denotes the major histocompatibility class II gene DRA
C6 197-226 NP denotes an octamer element (ATTTGCAT)
C7 227-231 NP denotes that
C8 332-345 NP denotes this sequence
C9 374-399 NP denotes the B cell-specific OTF-2
C10 404-424 NP denotes the ubiquitous OTF-1
C11 465-470 NP denotes OTF-2
C12 479-484 NP denotes OTF-1
C13 495-507 NP denotes the DRA gene
C14 578-611 NP denotes the octamer-binding protein OTF-2
C15 655-660 NP denotes OTF-2
C17 664-672 NP denotes DRA gene
C16 664-686 NP denotes DRA gene transcription
C18 701-733 NP denotes OTF-1-enriched protein fractions
C20 749-757 NP denotes DRA gene
C19 749-771 NP denotes DRA gene transcription
C21 781-783 NP denotes it
C23 933-941 NP denotes DRA gene
C22 933-964 NP denotes DRA gene transcription in vitro
C25 1100-1108 NP denotes DRA gene
C24 1100-1122 NP denotes DRA gene transcription
C28 1264-1308 NP denotes the lymphoid-specific octamer-binding factor
C27 1312-1320 NP denotes DRA gene
C26 1312-1334 NP denotes DRA gene transcription
R1 C4 C3 coref-appos DRA,the human class II transplantation gene
R2 C5 C4 coref-ident the major histocompatibility class II gene DRA,DRA
R3 C7 C6 coref-relat that,an octamer element (ATTTGCAT)
R4 C8 C6 coref-ident this sequence,an octamer element (ATTTGCAT)
R5 C9 C1 coref-other the B cell-specific OTF-2,The B cell-specific nuclear factor OTF-2
R6 C11 C9 coref-ident OTF-2,the B cell-specific OTF-2
R7 C12 C10 coref-ident OTF-1,the ubiquitous OTF-1
R8 C13 C5 coref-ident the DRA gene,the major histocompatibility class II gene DRA
R9 C14 C11 coref-other the octamer-binding protein OTF-2,OTF-2
R10 C15 C14 coref-other OTF-2,the octamer-binding protein OTF-2
R11 C17 C13 coref-ident DRA gene,the DRA gene
R12 C16 C2 coref-ident DRA gene transcription,"transcription of the human class II transplantation gene, DRA"
R13 C20 C17 coref-ident DRA gene,DRA gene
R14 C19 C16 coref-ident DRA gene transcription,DRA gene transcription
R15 C21 C18 coref-pron it,OTF-1-enriched protein fractions
R16 C23 C20 coref-ident DRA gene,DRA gene
R17 C22 C19 coref-other DRA gene transcription in vitro,DRA gene transcription
R18 C25 C23 coref-ident DRA gene,DRA gene
R19 C24 C19 coref-ident DRA gene transcription,DRA gene transcription
R20 C28 C14 coref-other the lymphoid-specific octamer-binding factor,the octamer-binding protein OTF-2
R21 C27 C25 coref-ident DRA gene,DRA gene
R22 C26 C24 coref-ident DRA gene transcription,DRA gene transcription

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-124 Sentence denotes The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
S2 125-284 Sentence denotes The promoter of the major histocompatibility class II gene DRA contains an octamer element (ATTTGCAT) that is required for efficient DRA expression in B cells.
S3 285-346 Sentence denotes Several DNA-binding proteins are known to bind this sequence.
S4 347-425 Sentence denotes The best characterized are the B cell-specific OTF-2 and the ubiquitous OTF-1.
S5 426-508 Sentence denotes This report directly demonstrates that OTF-2 but not OTF-1 regulates the DRA gene.
S6 509-687 Sentence denotes In vitro transcription analysis using protein fractions enriched for the octamer-binding protein OTF-2 demonstrate a positive functional role for OTF-2 in DRA gene transcription.
S7 688-840 Sentence denotes In contrast, OTF-1-enriched protein fractions did not affect DRA gene transcription although it functionally enhanced the transcription of another gene.
S8 841-965 Sentence denotes Recombinant OTF-2 protein produced by in vitro transcription/translation could also enhance DRA gene transcription in vitro.
S9 966-1180 Sentence denotes In vivo transient transfection studies utilizing an OTF-2 expression vector resulted in similar findings: that OTF-2 protein enhanced DRA gene transcription, and that this effect requires an intact octamer element.
S10 1181-1335 Sentence denotes Together these results constitute the first direct evidence of a positive role for the lymphoid-specific octamer-binding factor in DRA gene transcription.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-34 protein_family_or_group denotes B cell-specific nuclear factor
T2 35-40 protein_molecule denotes OTF-2
T3 62-75 other_name denotes transcription
T4 83-118 DNA_domain_or_region denotes human class II transplantation gene
T5 120-123 DNA_domain_or_region denotes DRA
T6 145-183 DNA_domain_or_region denotes major histocompatibility class II gene
T7 184-187 DNA_domain_or_region denotes DRA
T8 200-215 DNA_domain_or_region denotes octamer element
T9 217-225 polynucleotide denotes ATTTGCAT
T10 258-261 DNA_domain_or_region denotes DRA
T11 276-283 cell_type denotes B cells
T12 293-313 protein_family_or_group denotes DNA-binding proteins
T13 378-393 protein_molecule denotes B cell-specific
T14 394-399 protein_molecule denotes OTF-2
T15 419-424 protein_molecule denotes OTF-1
T16 465-470 protein_molecule denotes OTF-2
T17 479-484 protein_molecule denotes OTF-1
T18 499-507 DNA_domain_or_region denotes DRA gene
T19 518-531 other_name denotes transcription
T20 606-611 protein_molecule denotes OTF-2
T21 655-660 protein_molecule denotes OTF-2
T22 664-672 DNA_domain_or_region denotes DRA gene
T23 673-686 other_name denotes transcription
T24 701-706 protein_molecule denotes OTF-1
T25 749-757 DNA_domain_or_region denotes DRA gene
T26 758-771 other_name denotes transcription
T27 810-823 other_name denotes transcription
T28 841-852 protein_molecule denotes Recombinant
T29 853-858 protein_molecule denotes OTF-2
T30 879-887 other_name denotes in vitro
T31 888-901 other_name denotes transcription
T32 933-941 DNA_domain_or_region denotes DRA gene
T33 942-955 other_name denotes transcription
T34 966-1004 other_name denotes In vivo transient transfection studies
T35 1018-1023 protein_molecule denotes OTF-2
T36 1077-1082 protein_molecule denotes OTF-2
T37 1100-1108 DNA_domain_or_region denotes DRA gene
T38 1109-1122 other_name denotes transcription
T39 1164-1179 DNA_domain_or_region denotes octamer element
T40 1268-1308 protein_family_or_group denotes lymphoid-specific octamer-binding factor
T41 1312-1320 other_name denotes DRA gene
T42 1321-1334 other_name denotes transcription

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 120-123 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T2 184-187 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T3 258-261 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T4 499-502 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T5 664-667 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T6 749-752 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T7 933-936 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T8 1100-1103 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440
T9 1312-1315 Disease denotes DRA http://purl.obolibrary.org/obo/MONDO_0019440

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 83-88 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 4-10 Body_part denotes B cell http://purl.obolibrary.org/obo/CL_0000236
T2 378-384 Body_part denotes B cell http://purl.obolibrary.org/obo/CL_0000236

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 4-10 Cell denotes B cell http://purl.obolibrary.org/obo/CL:0000236
T2 276-283 Cell denotes B cells http://purl.obolibrary.org/obo/CL:0000236
T3 378-384 Cell denotes B cell http://purl.obolibrary.org/obo/CL:0000236