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c_corpus

Id Subject Object Predicate Lexical cue
T3 22-46 D002285 denotes ductal carcinoma in situ
T4 22-46 D002285 denotes ductal carcinoma in situ
T9 80-86 UBERON:0000310 denotes breast
T10 114-128 GO:0007150 denotes growth pattern
T11 114-128 GO:0040007 denotes growth pattern
T12 193-199 UBERON:0000310 denotes breast
T13 193-209 D001943 denotes breast carcinoma
T14 193-209 D001943 denotes breast carcinoma
T19 260-284 D002285 denotes ductal carcinoma in situ
T20 260-284 D002285 denotes ductal carcinoma in situ
T26 286-290 CVCL_5552 denotes DCIS
T25 286-290 D002285 denotes DCIS
T27 286-290 D002285 denotes DCIS
T29 349-353 CVCL_5552 denotes DCIS
T28 349-353 D002285 denotes DCIS
T30 349-353 D002285 denotes DCIS
T32 634-638 CVCL_5552 denotes DCIS
T31 634-638 D002285 denotes DCIS
T33 634-638 D002285 denotes DCIS
T34 646-652 UBERON:0000310 denotes breast
T35 897-905 GO:0019835 denotes necrosis
T36 897-905 GO:0008219 denotes necrosis
T39 897-905 GO:0008220 denotes necrosis
T40 897-905 GO:0001906 denotes necrosis
T41 897-905 GO:0070265 denotes necrosis
T37 897-905 D009336 denotes necrosis
T38 897-905 D009336 denotes necrosis
T42 907-926 D002114 denotes microcalcifications
T43 907-926 D002114 denotes microcalcifications
T46 1221-1225 CVCL_5552 denotes DCIS
T45 1221-1225 D002285 denotes DCIS
T47 1221-1225 D002285 denotes DCIS
T48 1409-1413 PR:Q8FYW3 denotes Pure
T49 1409-1413 PR:Q54QE4 denotes Pure
T50 1409-1413 PR:P52558 denotes Pure
T51 1409-1413 PR:P0AG18 denotes Pure
T53 1409-1413 PR:000023640 denotes Pure
T52 1409-1413 GO:0034023 denotes Pure
T55 1503-1507 CVCL_5552 denotes DCIS
T54 1503-1507 D002285 denotes DCIS
T56 1503-1507 D002285 denotes DCIS
T58 1533-1537 CVCL_5552 denotes DCIS
T57 1533-1537 D002285 denotes DCIS
T59 1533-1537 D002285 denotes DCIS
T61 1605-1609 CVCL_5552 denotes DCIS
T60 1605-1609 D002285 denotes DCIS
T62 1605-1609 D002285 denotes DCIS
T63 1650-1669 D002114 denotes Microcalcifications
T64 1650-1669 D002114 denotes Microcalcifications
T66 1792-1796 CVCL_5552 denotes DCIS
T65 1792-1796 D002285 denotes DCIS
T67 1792-1796 D002285 denotes DCIS
T69 1822-1826 CVCL_5552 denotes DCIS
T68 1822-1826 D002285 denotes DCIS
T70 1822-1826 D002285 denotes DCIS
T72 1922-1926 CVCL_5552 denotes DCIS
T71 1922-1926 D002285 denotes DCIS
T73 1922-1926 D002285 denotes DCIS
T74 1934-1940 UBERON:0000310 denotes breast
T75 1991-2005 GO:0007150 denotes growth pattern
T76 1991-2005 GO:0040007 denotes growth pattern

PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 168-478 BACKGROUND denotes Approximately 20% of the breast carcinoma cases detected on mammography screening represent ductal carcinoma in situ (DCIS). Cytopathologists are exposed to cytologic material from DCIS when nonpalpable, mammographic lesions are aspirated during the workup of organized and opportunistic mammography screening.
T2 488-965 METHODS denotes The material in the current study was comprised of 225 representative fine-needle aspiration cytology (FNAC) smears from histologically confirmed DCIS of the breast that were diagnosed between 1990-2003. Smears were rescreened to search for the following features: nuclear size (grading), monolayer sheets, solid and cribriform epithelial aggregates, micropapillary and true papillary structures, comedo-type necrosis, microcalcifications, myoepithelial cells, and discohesion.
T3 975-1882 RESULTS denotes There were 174 high-grade lesions (77% were Grade 3) and 51 nonhigh-grade lesions (Grades 1 and 2). The concordance between the cytologic and histologic grading was 97% in the Grade 3 lesions and 94% in the Grade 1/2 lesions. Smears from Grade 3 DCIS contained solid and/or cribriform epithelial aggregates in > 93%% of the cases, whereas smears from Grade 1/2 lesions were found to contain cribriform aggregates in 94% of the cases. Pure subtypes were virtually nonexistent. Monolayer sheets were found in 49% of nonhigh-grade DCIS and in 16% of high-grade DCIS. Myoepithelial cells were demonstrated in 51% of the nonhigh-grade DCIS lesions and 27% of the Grade 3 lesions. Microcalcifications were found on the smears from 96% of nonhigh-grade lesions and 84% of high-grade lesions. Approximately 47% of high-grade DCIS and 31% of nonhigh-grade DCIS were found to harbor a distinct single cell population.
T4 1896-2121 CONCLUSIONS denotes The findings on FNAC from DCIS of the breast completely mirror the histologic heterogeneity of growth pattern subtypes. Primary cytologic grading can effectively separate the high-grade lesions from the nonhigh-grade lesions.