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PubMed:15572352
Annnotations
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-97 | Sentence | denotes | A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. |
T2 | 98-299 | Sentence | denotes | Among the members of the major facilitator superfamily of Saccharomyces cerevisiae, we identified genes involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine. |
T3 | 300-532 | Sentence | denotes | ATP-dependent uptake of histidine and lysine by isolated vacuolar membrane vesicles was impaired in YMR088c, a vacuolar basic amino acid transporter 1 (VBA1)-deleted strain, whereas uptake of tyrosine or calcium was little affected. |
T4 | 533-775 | Sentence | denotes | This defect in histidine and lysine uptake was complemented fully by introducing the VBA1 gene and partially by a gene encoding Vba1p fused with green fluorescent protein, which was determined to localize exclusively to the vacuolar membrane. |
T5 | 776-930 | Sentence | denotes | A defect in the uptake of histidine, lysine, or arginine was also observed in the vacuolar membrane vesicles of mutants YBR293w (VBA2) and YCL069w (VBA3). |
T6 | 931-1072 | Sentence | denotes | These three VBA genes are closely related phylogenetically and constitute a new family of basic amino acid transporters in the yeast vacuole. |
LocText
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 49-66 | go:GO:0005774 | denotes | vacuolar membrane |
T2 | 72-96 | taxonomy:4932 | denotes | Saccharomyces cerevisiae |
T3 | 156-180 | taxonomy:4932 | denotes | Saccharomyces cerevisiae |
T4 | 233-241 | go:GO:0005773 | denotes | vacuoles |
T5 | 357-374 | go:GO:0005774 | denotes | vacuolar membrane |
T6 | 400-407 | uniprot:Q04301 | denotes | YMR088c |
T7 | 411-450 | uniprot:Q04301 | denotes | vacuolar basic amino acid transporter 1 |
T8 | 452-456 | uniprot:Q04301 | denotes | VBA1 |
T9 | 618-622 | uniprot:Q04301 | denotes | VBA1 |
T10 | 661-666 | uniprot:Q04301 | denotes | Vba1p |
T11 | 678-703 | uniprot:uniprot: | denotes | green fluorescent protein |
T12 | 757-774 | go:GO:0005774 | denotes | vacuolar membrane |
T13 | 858-875 | go:GO:0005774 | denotes | vacuolar membrane |
T14 | 896-903 | uniprot:P38358 | denotes | YBR293w |
T15 | 905-909 | uniprot:P38358 | denotes | VBA2 |
T16 | 915-922 | uniprot:P25594 | denotes | YCL069w |
T17 | 924-928 | uniprot:P25594 | denotes | VBA3 |
T18 | 1058-1063 | taxonomy:4932 | denotes | yeast |
T19 | 1064-1071 | go:GO:0005773 | denotes | vacuole |
R1 | T6 | T4 | localizeTo | YMR088c,vacuoles |
R2 | T7 | T4 | localizeTo | vacuolar basic amino acid transporter 1,vacuoles |
R3 | T8 | T4 | localizeTo | VBA1,vacuoles |
R4 | T6 | T5 | localizeTo | YMR088c,vacuolar membrane |
R5 | T7 | T5 | localizeTo | vacuolar basic amino acid transporter 1,vacuolar membrane |
R6 | T8 | T5 | localizeTo | VBA1,vacuolar membrane |
R7 | T9 | T12 | localizeTo | VBA1,vacuolar membrane |
R8 | T10 | T12 | localizeTo | Vba1p,vacuolar membrane |
R9 | T14 | T13 | localizeTo | YBR293w,vacuolar membrane |
R10 | T15 | T13 | localizeTo | VBA2,vacuolar membrane |
R11 | T16 | T13 | localizeTo | YCL069w,vacuolar membrane |
R12 | T17 | T13 | localizeTo | VBA3,vacuolar membrane |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 72-96 | OrganismTaxon | denotes | Saccharomyces cerevisiae | 4932 |
T2 | 156-180 | OrganismTaxon | denotes | Saccharomyces cerevisiae | 4932 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 49-66 | Body_part | denotes | vacuolar membrane | http://purl.obolibrary.org/obo/GO_0005774 |
T2 | 357-374 | Body_part | denotes | vacuolar membrane | http://purl.obolibrary.org/obo/GO_0005774 |
T3 | 757-774 | Body_part | denotes | vacuolar membrane | http://purl.obolibrary.org/obo/GO_0005774 |
T4 | 858-875 | Body_part | denotes | vacuolar membrane | http://purl.obolibrary.org/obo/GO_0005774 |
T5 | 1064-1071 | Body_part | denotes | vacuole | http://purl.obolibrary.org/obo/GO_0005773 |