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PubMed:15572352 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.
T2 98-299 Sentence denotes Among the members of the major facilitator superfamily of Saccharomyces cerevisiae, we identified genes involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine.
T3 300-532 Sentence denotes ATP-dependent uptake of histidine and lysine by isolated vacuolar membrane vesicles was impaired in YMR088c, a vacuolar basic amino acid transporter 1 (VBA1)-deleted strain, whereas uptake of tyrosine or calcium was little affected.
T4 533-775 Sentence denotes This defect in histidine and lysine uptake was complemented fully by introducing the VBA1 gene and partially by a gene encoding Vba1p fused with green fluorescent protein, which was determined to localize exclusively to the vacuolar membrane.
T5 776-930 Sentence denotes A defect in the uptake of histidine, lysine, or arginine was also observed in the vacuolar membrane vesicles of mutants YBR293w (VBA2) and YCL069w (VBA3).
T6 931-1072 Sentence denotes These three VBA genes are closely related phylogenetically and constitute a new family of basic amino acid transporters in the yeast vacuole.

LocText

Id Subject Object Predicate Lexical cue
T1 49-66 go:GO:0005774 denotes vacuolar membrane
T2 72-96 taxonomy:4932 denotes Saccharomyces cerevisiae
T3 156-180 taxonomy:4932 denotes Saccharomyces cerevisiae
T4 233-241 go:GO:0005773 denotes vacuoles
T5 357-374 go:GO:0005774 denotes vacuolar membrane
T6 400-407 uniprot:Q04301 denotes YMR088c
T7 411-450 uniprot:Q04301 denotes vacuolar basic amino acid transporter 1
T8 452-456 uniprot:Q04301 denotes VBA1
T9 618-622 uniprot:Q04301 denotes VBA1
T10 661-666 uniprot:Q04301 denotes Vba1p
T11 678-703 uniprot:uniprot: denotes green fluorescent protein
T12 757-774 go:GO:0005774 denotes vacuolar membrane
T13 858-875 go:GO:0005774 denotes vacuolar membrane
T14 896-903 uniprot:P38358 denotes YBR293w
T15 905-909 uniprot:P38358 denotes VBA2
T16 915-922 uniprot:P25594 denotes YCL069w
T17 924-928 uniprot:P25594 denotes VBA3
T18 1058-1063 taxonomy:4932 denotes yeast
T19 1064-1071 go:GO:0005773 denotes vacuole
R1 T6 T4 localizeTo YMR088c,vacuoles
R2 T7 T4 localizeTo vacuolar basic amino acid transporter 1,vacuoles
R3 T8 T4 localizeTo VBA1,vacuoles
R4 T6 T5 localizeTo YMR088c,vacuolar membrane
R5 T7 T5 localizeTo vacuolar basic amino acid transporter 1,vacuolar membrane
R6 T8 T5 localizeTo VBA1,vacuolar membrane
R7 T9 T12 localizeTo VBA1,vacuolar membrane
R8 T10 T12 localizeTo Vba1p,vacuolar membrane
R9 T14 T13 localizeTo YBR293w,vacuolar membrane
R10 T15 T13 localizeTo VBA2,vacuolar membrane
R11 T16 T13 localizeTo YCL069w,vacuolar membrane
R12 T17 T13 localizeTo VBA3,vacuolar membrane

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 72-96 OrganismTaxon denotes Saccharomyces cerevisiae 4932
T2 156-180 OrganismTaxon denotes Saccharomyces cerevisiae 4932

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 49-66 Body_part denotes vacuolar membrane http://purl.obolibrary.org/obo/GO_0005774
T2 357-374 Body_part denotes vacuolar membrane http://purl.obolibrary.org/obo/GO_0005774
T3 757-774 Body_part denotes vacuolar membrane http://purl.obolibrary.org/obo/GO_0005774
T4 858-875 Body_part denotes vacuolar membrane http://purl.obolibrary.org/obo/GO_0005774
T5 1064-1071 Body_part denotes vacuole http://purl.obolibrary.org/obo/GO_0005773