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PubMed:15525818 JSONTXT

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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 824-838 Cell denotes cultured cells http://purl.obolibrary.org/obo/CL:0000010
T2 926-936 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394

Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 1004-1011 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1004-1011 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1004-1011 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 62-69 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessels
T2 1081-1087 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessel

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-94 Sentence denotes Increased expression of protein C-mannosylation in the aortic vessels of diabetic Zucker rats.
TextSentencer_T2 95-156 Sentence denotes C-Mannosylation is a novel type of glycosylation in proteins.
TextSentencer_T3 157-305 Sentence denotes There are several examples of proteins in which the specific motif Trp-X-X-Trp is mannosylated at the first Trp to produce C-mannosylated Trp (CMW).
TextSentencer_T4 306-539 Sentence denotes Although C-mannosylation modifies Trp-X-X-Trp, predicted to be a functional motif of various integral proteins such as cytokine receptors, the physiological or pathological relevance of C-mannosylation in the cell is still not known.
TextSentencer_T5 540-718 Sentence denotes In this study, to characterize C-mannosylation in biological samples, we generated specific polyclonal antibodies against CMW by using a chemically synthesized CMW as an antigen.
TextSentencer_T6 719-870 Sentence denotes Using the antibody, we investigated the effect of hyperglycemic conditions on protein C-mannosylation in cultured cells and diabetic Zucker fatty rats.
TextSentencer_T7 871-1023 Sentence denotes We found that protein C-mannosylation was increased in macrophage-like RAW264.7 cells under hyperglycemic conditions compared to low-glucose conditions.
TextSentencer_T8 1024-1114 Sentence denotes Furthermore, C-mannosylation was increased in the aortic vessel wall of Zucker fatty rats.
TextSentencer_T9 1115-1272 Sentence denotes Thrombospondin-1 was identified as a protein modified with C-mannosylation, and its expression was also increased in the aortic tissues of Zucker fatty rats.
TextSentencer_T10 1273-1506 Sentence denotes These results indicate that C-mannosylation is increased in specific tissues or cell types under hyperglycemic conditions, suggesting a pathological role for the increased C-mannosylation in the development of diabetic complications.
T1 0-94 Sentence denotes Increased expression of protein C-mannosylation in the aortic vessels of diabetic Zucker rats.
T2 95-156 Sentence denotes C-Mannosylation is a novel type of glycosylation in proteins.
T3 157-305 Sentence denotes There are several examples of proteins in which the specific motif Trp-X-X-Trp is mannosylated at the first Trp to produce C-mannosylated Trp (CMW).
T4 306-539 Sentence denotes Although C-mannosylation modifies Trp-X-X-Trp, predicted to be a functional motif of various integral proteins such as cytokine receptors, the physiological or pathological relevance of C-mannosylation in the cell is still not known.
T5 540-718 Sentence denotes In this study, to characterize C-mannosylation in biological samples, we generated specific polyclonal antibodies against CMW by using a chemically synthesized CMW as an antigen.
T6 719-870 Sentence denotes Using the antibody, we investigated the effect of hyperglycemic conditions on protein C-mannosylation in cultured cells and diabetic Zucker fatty rats.
T7 871-1023 Sentence denotes We found that protein C-mannosylation was increased in macrophage-like RAW264.7 cells under hyperglycemic conditions compared to low-glucose conditions.
T8 1024-1114 Sentence denotes Furthermore, C-mannosylation was increased in the aortic vessel wall of Zucker fatty rats.
T9 1115-1272 Sentence denotes Thrombospondin-1 was identified as a protein modified with C-mannosylation, and its expression was also increased in the aortic tissues of Zucker fatty rats.
T10 1273-1506 Sentence denotes These results indicate that C-mannosylation is increased in specific tissues or cell types under hyperglycemic conditions, suggesting a pathological role for the increased C-mannosylation in the development of diabetic complications.
T1 0-94 Sentence denotes Increased expression of protein C-mannosylation in the aortic vessels of diabetic Zucker rats.
T2 95-156 Sentence denotes C-Mannosylation is a novel type of glycosylation in proteins.
T3 157-305 Sentence denotes There are several examples of proteins in which the specific motif Trp-X-X-Trp is mannosylated at the first Trp to produce C-mannosylated Trp (CMW).
T4 306-539 Sentence denotes Although C-mannosylation modifies Trp-X-X-Trp, predicted to be a functional motif of various integral proteins such as cytokine receptors, the physiological or pathological relevance of C-mannosylation in the cell is still not known.
T5 540-718 Sentence denotes In this study, to characterize C-mannosylation in biological samples, we generated specific polyclonal antibodies against CMW by using a chemically synthesized CMW as an antigen.
T6 719-870 Sentence denotes Using the antibody, we investigated the effect of hyperglycemic conditions on protein C-mannosylation in cultured cells and diabetic Zucker fatty rats.
T7 871-1023 Sentence denotes We found that protein C-mannosylation was increased in macrophage-like RAW264.7 cells under hyperglycemic conditions compared to low-glucose conditions.
T8 1024-1114 Sentence denotes Furthermore, C-mannosylation was increased in the aortic vessel wall of Zucker fatty rats.
T9 1115-1272 Sentence denotes Thrombospondin-1 was identified as a protein modified with C-mannosylation, and its expression was also increased in the aortic tissues of Zucker fatty rats.
T10 1273-1506 Sentence denotes These results indicate that C-mannosylation is increased in specific tissues or cell types under hyperglycemic conditions, suggesting a pathological role for the increased C-mannosylation in the development of diabetic complications.

uniprot-human

Id Subject Object Predicate Lexical cue
T1 1115-1131 http://www.uniprot.org/uniprot/P07996 denotes Thrombospondin-1

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 224-227 http://www.uniprot.org/uniprot/P62340 denotes Trp
T2 232-235 http://www.uniprot.org/uniprot/P62340 denotes Trp
T3 265-268 http://www.uniprot.org/uniprot/P62340 denotes Trp
T4 295-298 http://www.uniprot.org/uniprot/P62340 denotes Trp
T5 340-343 http://www.uniprot.org/uniprot/P62340 denotes Trp
T6 348-351 http://www.uniprot.org/uniprot/P62340 denotes Trp
T7 1115-1131 http://www.uniprot.org/uniprot/P35441 denotes Thrombospondin-1

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 434-443 http://purl.bioontology.org/ontology/STY/T192 denotes receptors
T2 833-838 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 951-956 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T4 1243-1250 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T5 1342-1349 http://purl.bioontology.org/ontology/STY/T024 denotes tissues

GO-BP

Id Subject Object Predicate Lexical cue
T1 34-47 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T2 317-330 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T3 494-507 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T4 573-586 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T5 807-820 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T6 895-908 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T7 1039-1052 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T8 1176-1189 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T9 1303-1316 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T10 97-110 http://purl.obolibrary.org/obo/GO_0097502 denotes Mannosylation
T11 239-251 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylated
T12 282-294 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylated
T13 130-143 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T14 130-155 http://purl.obolibrary.org/obo/GO_0006486 denotes glycosylation in proteins
T15 1468-1479 http://purl.obolibrary.org/obo/GO_0032502 denotes development

GO-MF

Id Subject Object Predicate Lexical cue
T1 643-653 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T2 729-737 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T1 515-519 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 833-838 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 951-956 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 62-69 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessels
T2 1081-1087 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T3 1243-1250 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T4 1342-1349 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 62-69 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessels
T2 1081-1087 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessel

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 62-69 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessels
PD-UBERON-AE-B_T2 1081-1087 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
PD-UBERON-AE-B_T3 1243-1250 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T4 1342-1349 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 62-69 Body_part denotes vessels http://purl.obolibrary.org/obo/MAT_0000393
T2 1081-1087 Body_part denotes vessel http://purl.obolibrary.org/obo/MAT_0000393

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 89-93 OrganismTaxon denotes rats 10114|10116
T3 865-869 OrganismTaxon denotes rats 10114|10116
T5 1109-1113 OrganismTaxon denotes rats 10114|10116
T7 1267-1271 OrganismTaxon denotes rats 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 926-936 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T2 1081-1087 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T3 1088-1092 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060