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PubMed:15470230 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 95-100 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T2 135-140 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T3 250-255 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T4 349-354 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T5 686-699 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T6 686-699 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T7 686-699 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T8 880-893 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T9 880-893 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T10 880-893 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T11 1075-1088 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T12 1075-1088 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T13 1075-1088 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T14 1213-1232 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T15 1810-1815 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1

ggdb-test

Id Subject Object Predicate Lexical cue
T1 250-258 https://acgg.asia/db/ggdb/info/gg035 denotes HNK-1 ST

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 95-100 Glycan_Motif denotes HNK-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD
T2 135-140 Glycan_Motif denotes HNK-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD
T3 250-255 Glycan_Motif denotes HNK-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD
T4 349-354 Glycan_Motif denotes HNK-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD
T5 686-699 Glycan_Motif denotes paragloboside https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58896AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48059CD|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40585SO
T8 880-893 Glycan_Motif denotes paragloboside https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58896AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48059CD|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40585SO
T11 1075-1088 Glycan_Motif denotes paragloboside https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58896AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48059CD|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40585SO
T14 1213-1232 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T15 1810-1815 Glycan_Motif denotes HNK-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD

GGDB-2020

Id Subject Object Predicate Lexical cue
T1 250-258 https://acgg.asia/db/ggdb/info/gg035 denotes HNK-1 ST

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 95-100 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T2 135-140 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T3 250-255 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T4 349-354 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1
T5 686-699 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T6 686-699 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T7 686-699 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T8 880-893 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T9 880-893 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T10 880-893 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T11 1075-1088 https://glytoucan.org/Structures/Glycans/G40585SO denotes paragloboside
T12 1075-1088 https://glytoucan.org/Structures/Glycans/G48059CD denotes paragloboside
T13 1075-1088 https://glytoucan.org/Structures/Glycans/G58896AZ denotes paragloboside
T14 1213-1232 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T15 1810-1815 https://glytoucan.org/Structures/Glycans/G54406UD denotes HNK-1

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
TextSentencer_T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
TextSentencer_T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
TextSentencer_T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
TextSentencer_T5 701-838 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S.
TextSentencer_T6 839-975 Sentence denotes The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
TextSentencer_T7 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
TextSentencer_T8 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
TextSentencer_T9 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
TextSentencer_T10 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
TextSentencer_T11 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.
T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
T5 701-975 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S. The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
T6 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
T7 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
T8 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
T9 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
T10 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.
T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
T5 701-838 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S.
T6 839-975 Sentence denotes The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
T7 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
T8 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
T9 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
T10 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
T11 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 95-100 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
T2 135-140 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
T3 250-255 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
T4 349-354 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
T5 686-699 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside
T6 880-893 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside
T7 1075-1088 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside
T8 1810-1815 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1837-1851 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system

ICD10

Id Subject Object Predicate Lexical cue
T1 1837-1844 http://purl.bioontology.org/ontology/ICD10/R45.0 denotes nervous

uniprot-human

Id Subject Object Predicate Lexical cue
T1 211-222 http://www.uniprot.org/uniprot/Q9P2W7 denotes P and GlcAT
T2 404-415 http://www.uniprot.org/uniprot/Q9P2W7 denotes P and GlcAT
T3 539-550 http://www.uniprot.org/uniprot/Q9P2W7 denotes P and GlcAT
T4 217-224 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T5 410-417 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T6 545-552 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T7 830-837 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T8 1318-1325 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T9 1578-1585 http://www.uniprot.org/uniprot/Q9NPZ5 denotes GlcAT-S
T10 232-255 http://www.uniprot.org/uniprot/O43529 denotes sulfotransferase (HNK-1
T11 1533-1537 http://www.uniprot.org/uniprot/Q59FL7 denotes NCAM
T12 1619-1623 http://www.uniprot.org/uniprot/Q59FL7 denotes NCAM

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 211-222 http://www.uniprot.org/uniprot/Q9CW73 denotes P and GlcAT
T2 404-415 http://www.uniprot.org/uniprot/Q9CW73 denotes P and GlcAT
T3 539-550 http://www.uniprot.org/uniprot/Q9CW73 denotes P and GlcAT
T4 217-224 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T5 410-417 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T6 545-552 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T7 830-837 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T8 1318-1325 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T9 1578-1585 http://www.uniprot.org/uniprot/P59270 denotes GlcAT-S
T10 232-255 http://www.uniprot.org/uniprot/Q6PGK7 denotes sulfotransferase (HNK-1
T11 256-258 http://www.uniprot.org/uniprot/P50236 denotes ST
T12 256-258 http://www.uniprot.org/uniprot/P52843 denotes ST
T13 418-423 http://www.uniprot.org/uniprot/O35625 denotes fused

GO-BP

Id Subject Object Predicate Lexical cue
T1 79-91 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T2 119-131 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T3 329-341 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T4 101-131 http://purl.obolibrary.org/obo/GO_0016051 denotes carbohydrate. The biosynthesis
T5 164-173 http://purl.obolibrary.org/obo/GO_0065007 denotes regulated
T6 582-586 http://purl.obolibrary.org/obo/GO_0043879 denotes GlcA
T7 1525-1529 http://purl.obolibrary.org/obo/GO_0043879 denotes GlcA

GO-MF

Id Subject Object Predicate Lexical cue
T1 433-444 http://purl.obolibrary.org/obo/GO_0019864 denotes IgG-binding
T2 437-444 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 437-444 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T4 437-444 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T5 437-444 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T6 437-462 http://purl.obolibrary.org/obo/GO_0019904 denotes binding domain of protein
T7 437-462 http://purl.obolibrary.org/obo/GO_0089719 denotes binding domain of protein

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 1837-1851 http://purl.obolibrary.org/obo/UBERON_0001016 denotes nervous system

glycogenes

Id Subject Object Predicate Lexical cue
PD-GlycoGenes20190927-B_T1 205-212 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T2 217-222 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT
PD-GlycoGenes20190927-B_T3 250-258 https://acgg.asia/db/ggdb/info/gg035 denotes HNK-1 ST
PD-GlycoGenes20190927-B_T4 398-405 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T5 410-415 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT
PD-GlycoGenes20190927-B_T6 533-540 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T7 545-550 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT
PD-GlycoGenes20190927-B_T8 717-724 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T9 830-835 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT
PD-GlycoGenes20190927-B_T10 1025-1032 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T11 1181-1188 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T12 1318-1323 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT
PD-GlycoGenes20190927-B_T13 1505-1512 https://acgg.asia/db/ggdb/info/gg157 denotes GlcAT-P
PD-GlycoGenes20190927-B_T14 1578-1583 https://acgg.asia/db/ggdb/info/gg156 denotes GlcAT

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 1837-1851 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 95-100 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
PD-GlycoEpitope-B_T2 135-140 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
PD-GlycoEpitope-B_T3 250-255 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
PD-GlycoEpitope-B_T4 349-354 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
PD-GlycoEpitope-B_T5 1810-1815 http://www.glycoepitope.jp/epitopes/EP0001 denotes HNK-1
PD-GlycoEpitope-B_T6 686-699 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside
PD-GlycoEpitope-B_T7 880-893 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside
PD-GlycoEpitope-B_T8 1075-1088 http://www.glycoepitope.jp/epitopes/EP0075 denotes paragloboside

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 582-586 "http://rdf.glycoinfo.org/glycan/G91489RT" denotes GlcA
GlycanIUPAC_T2 1525-1529 "http://rdf.glycoinfo.org/glycan/G91489RT" denotes GlcA
GlycanIUPAC_T3 582-586 "http://rdf.glycoinfo.org/glycan/G54004DL" denotes GlcA
GlycanIUPAC_T4 1525-1529 "http://rdf.glycoinfo.org/glycan/G54004DL" denotes GlcA
GlycanIUPAC_T5 582-586 "http://rdf.glycoinfo.org/glycan/G90208ZS" denotes GlcA
GlycanIUPAC_T6 1525-1529 "http://rdf.glycoinfo.org/glycan/G90208ZS" denotes GlcA
GlycanIUPAC_T7 582-586 "http://rdf.glycoinfo.org/glycan/G47973RQ" denotes GlcA
GlycanIUPAC_T8 1525-1529 "http://rdf.glycoinfo.org/glycan/G47973RQ" denotes GlcA
GlycanIUPAC_T9 582-586 "http://rdf.glycoinfo.org/glycan/G35471RR" denotes GlcA
GlycanIUPAC_T10 1525-1529 "http://rdf.glycoinfo.org/glycan/G35471RR" denotes GlcA
GlycanIUPAC_T11 582-586 "http://rdf.glycoinfo.org/glycan/G45399NV" denotes GlcA
GlycanIUPAC_T12 1525-1529 "http://rdf.glycoinfo.org/glycan/G45399NV" denotes GlcA
GlycanIUPAC_T13 582-586 "http://rdf.glycoinfo.org/glycan/G52061FU" denotes GlcA
GlycanIUPAC_T14 1525-1529 "http://rdf.glycoinfo.org/glycan/G52061FU" denotes GlcA
GlycanIUPAC_T15 582-586 "http://rdf.glycoinfo.org/glycan/G10736YH" denotes GlcA
GlycanIUPAC_T16 1525-1529 "http://rdf.glycoinfo.org/glycan/G10736YH" denotes GlcA
GlycanIUPAC_T17 582-586 "http://rdf.glycoinfo.org/glycan/G30254CI" denotes GlcA
GlycanIUPAC_T18 1525-1529 "http://rdf.glycoinfo.org/glycan/G30254CI" denotes GlcA
GlycanIUPAC_T19 582-586 "http://rdf.glycoinfo.org/glycan/G57856MN" denotes GlcA
GlycanIUPAC_T20 1525-1529 "http://rdf.glycoinfo.org/glycan/G57856MN" denotes GlcA
GlycanIUPAC_T21 582-586 "http://rdf.glycoinfo.org/glycan/G95754KF" denotes GlcA
GlycanIUPAC_T22 1525-1529 "http://rdf.glycoinfo.org/glycan/G95754KF" denotes GlcA
GlycanIUPAC_T23 582-586 "http://rdf.glycoinfo.org/glycan/G90067UQ" denotes GlcA
GlycanIUPAC_T24 1525-1529 "http://rdf.glycoinfo.org/glycan/G90067UQ" denotes GlcA

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1837-1851 http://purl.obolibrary.org/obo/UBERON_0001016 denotes nervous system

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1837-1851 Body_part denotes nervous system http://purl.obolibrary.org/obo/MAT_0000026

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 95-100 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T2 135-140 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T3 250-255 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T4 349-354 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T5 686-699 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T6 880-893 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T7 1075-1088 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T8 1810-1815 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1837-1851 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1837-1851 Body_part denotes nervous system http://purl.obolibrary.org/obo/MAT_0000026

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
TextSentencer_T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
TextSentencer_T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
TextSentencer_T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
TextSentencer_T5 701-838 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S.
TextSentencer_T6 839-975 Sentence denotes The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
TextSentencer_T7 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
TextSentencer_T8 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
TextSentencer_T9 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
TextSentencer_T10 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
TextSentencer_T11 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.
T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
T5 701-975 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S. The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
T6 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
T7 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
T8 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
T9 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
T10 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.
T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
T5 701-838 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S.
T6 839-975 Sentence denotes The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
T7 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
T8 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
T9 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
T10 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
T11 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-114 Sentence denotes Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate.
T2 115-260 Sentence denotes The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST).
T3 261-527 Sentence denotes To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes.
T4 528-700 Sentence denotes Both GlcAT-P and GlcAT-S transferred glucuronic acid (GlcA) not only to a glycoprotein acceptor, asialoorosomucoid (ASOR), but also to a glycolipid acceptor, paragloboside.
T5 701-975 Sentence denotes The activity of GlcAT-P toward ASOR was enhanced fivefold in the presence of sphingomyelin, but there were no effects on that of GlcAT-S. The activities of the two enzymes toward paragloboside were only detected in the presence of phospholipids such as phosphatidylinositol.
T6 976-1089 Sentence denotes Kinetic analysis revealed that the K(m) value of GlcAT-P for ASOR was 10 times lower than that for paragloboside.
T7 1090-1304 Sentence denotes Furthermore, acceptor specificity analysis involving various oligosaccarides revealed that GlcAT-P specifically recognized N-acetyllactosamine (Galbeta1-4GlcNAc) at the nonreducing terminals of acceptor substrates.
T8 1305-1504 Sentence denotes In contrast, GlcAT-S recognized not only the terminal Galbeta1-4GlcNAc structure but also the Galbeta1-3GlcNAc structure and showed the highest activity toward triantennary N-linked oligosaccharides.
T9 1505-1624 Sentence denotes GlcAT-P transferred GlcA to NCAM about twice as much as to ASOR, whereas GlcAT-S did not show any activity toward NCAM.
T10 1625-1852 Sentence denotes These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 95-100 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T2 135-140 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T3 250-255 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T4 349-354 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD
T5 686-699 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T6 880-893 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T7 1075-1088 Glycan denotes paragloboside https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ
T8 1810-1815 Glycan denotes HNK-1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 95-100 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T2 135-140 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T3 250-255 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T4 349-354 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T5 686-699 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T6 880-893 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T7 1075-1088 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T8 1810-1815 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 95-100 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T2 135-140 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T3 250-255 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T4 349-354 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001
T5 686-699 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T6 880-893 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T7 1075-1088 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes paragloboside http://www.glycoepitope.jp/epitopes/EP0075
T8 1810-1815 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HNK-1 http://www.glycoepitope.jp/epitopes/EP0001

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1837-1851 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016