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GlyCosmos15-Species

Id Subject Object Predicate Lexical cue db_id
3 4-9 Species denotes human 9606
59 516-521 Species denotes human 9606
61 598-603 Species denotes human 9606
62 621-626 Species denotes yeast 4932
66 771-776 Species denotes yeast 4932
74 1053-1058 Species denotes human 9606
84 1652-1657 Species denotes human 9606

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 394-413 Glycan_Motif denotes galactosylceramides https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T2 418-428 Glycan_Motif denotes sulfatides https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T5 1765-1784 Glycan_Motif denotes galactosylceramides https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T6 1790-1800 Glycan_Motif denotes sulfatides https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY

sentences

Id Subject Object Predicate Lexical cue
T1 0-55 Sentence denotes The human FA2H gene encodes a fatty acid 2-hydroxylase.
T2 56-142 Sentence denotes 2-Hydroxysphingolipids are a subset of sphingolipids containing 2-hydroxy fatty acids.
T3 143-294 Sentence denotes The 2-hydroxylation occurs during de novo ceramide synthesis and is catalyzed by fatty acid 2-hydroxylase (also known as fatty acid alpha-hydroxylase).
T4 295-459 Sentence denotes In mammals, 2-hydroxysphingolipids are present abundantly in brain because the major myelin lipids galactosylceramides and sulfatides contain 2-hydroxy fatty acids.
T5 460-567 Sentence denotes Here we report identification and characterization of a human gene that encodes a fatty acid 2-hydroxylase.
T6 568-683 Sentence denotes Data base searches revealed a human homologue of the yeast ceramide 2-hydroxylase gene (FAH1), which we named FA2H.
T7 684-783 Sentence denotes The FA2H gene encodes a 372-amino acid protein with 36% identity and 46% similarity to yeast Fah1p.
T8 784-921 Sentence denotes The amino acid sequence indicates that FA2H protein contains an N-terminal cytochrome b5 domain and four potential transmembrane domains.
T9 922-1030 Sentence denotes FA2H also contains the iron-binding histidine motif conserved among membrane-bound desaturases/hydroxylases.
T10 1031-1201 Sentence denotes COS7 cells expressing human FA2H contained 3-20-fold higher levels of 2-hydroxyceramides (C16, C18, C24, and C24:1) and 2-hydroxy fatty acids compared with control cells.
T11 1202-1379 Sentence denotes Microsomal fractions prepared from transfected COS7 cells showed tetracosanoic acid 2-hydroxylase activities in an NADPH- and NADPH: cytochrome P-450 reductase-dependent manner.
T12 1380-1519 Sentence denotes FA2H lacking the N-terminal cytochrome b5 domain had little activity, indicating that this domain is a functional component of this enzyme.
T13 1520-1616 Sentence denotes Northern blot analysis showed that the FA2H gene is highly expressed in brain and colon tissues.
T14 1617-1703 Sentence denotes These results demonstrate that the human FA2H gene encodes a fatty acid 2-hydroxylase.
T15 1704-1801 Sentence denotes FA2H is likely involved in the formation of myelin 2-hydroxy galactosylceramides and -sulfatides.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 394-413 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactosylceramides
T2 418-428 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatides
T3 418-428 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatides
T4 418-428 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatides
T5 1765-1784 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactosylceramides
T6 1790-1800 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatides
T7 1790-1800 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatides
T8 1790-1800 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatides

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 356-361 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 1592-1597 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 1602-1607 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 394-413 http://www.glycoepitope.jp/epitopes/EP0074 denotes galactosylceramides
T2 1765-1784 http://www.glycoepitope.jp/epitopes/EP0074 denotes galactosylceramides

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 394-413 Glycan denotes galactosylceramides https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE
T2 1765-1784 Glycan denotes galactosylceramides https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 394-413 Glycan denotes galactosylceramides https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE
T2 1765-1784 Glycan denotes galactosylceramides https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 394-413 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramides http://www.glycoepitope.jp/epitopes/EP0074
T2 1765-1784 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramides http://www.glycoepitope.jp/epitopes/EP0074

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 4-9 OrganismTaxon denotes human 9606
T2 516-521 OrganismTaxon denotes human 9606
T3 598-603 OrganismTaxon denotes human 9606
T4 1053-1058 OrganismTaxon denotes human 9606
T5 1652-1657 OrganismTaxon denotes human 9606

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 356-361 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T3 380-386 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T4 899-912 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T5 990-998 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T8 1592-1597 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T10 1602-1607 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T11 1748-1754 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-55 Sentence denotes The human FA2H gene encodes a fatty acid 2-hydroxylase.
T2 56-142 Sentence denotes 2-Hydroxysphingolipids are a subset of sphingolipids containing 2-hydroxy fatty acids.
T3 143-294 Sentence denotes The 2-hydroxylation occurs during de novo ceramide synthesis and is catalyzed by fatty acid 2-hydroxylase (also known as fatty acid alpha-hydroxylase).
T4 295-459 Sentence denotes In mammals, 2-hydroxysphingolipids are present abundantly in brain because the major myelin lipids galactosylceramides and sulfatides contain 2-hydroxy fatty acids.
T5 460-567 Sentence denotes Here we report identification and characterization of a human gene that encodes a fatty acid 2-hydroxylase.
T6 568-683 Sentence denotes Data base searches revealed a human homologue of the yeast ceramide 2-hydroxylase gene (FAH1), which we named FA2H.
T7 684-783 Sentence denotes The FA2H gene encodes a 372-amino acid protein with 36% identity and 46% similarity to yeast Fah1p.
T8 784-921 Sentence denotes The amino acid sequence indicates that FA2H protein contains an N-terminal cytochrome b5 domain and four potential transmembrane domains.
T9 922-1030 Sentence denotes FA2H also contains the iron-binding histidine motif conserved among membrane-bound desaturases/hydroxylases.
T10 1031-1201 Sentence denotes COS7 cells expressing human FA2H contained 3-20-fold higher levels of 2-hydroxyceramides (C16, C18, C24, and C24:1) and 2-hydroxy fatty acids compared with control cells.
T11 1202-1379 Sentence denotes Microsomal fractions prepared from transfected COS7 cells showed tetracosanoic acid 2-hydroxylase activities in an NADPH- and NADPH: cytochrome P-450 reductase-dependent manner.
T12 1380-1519 Sentence denotes FA2H lacking the N-terminal cytochrome b5 domain had little activity, indicating that this domain is a functional component of this enzyme.
T13 1520-1616 Sentence denotes Northern blot analysis showed that the FA2H gene is highly expressed in brain and colon tissues.
T14 1617-1703 Sentence denotes These results demonstrate that the human FA2H gene encodes a fatty acid 2-hydroxylase.
T15 1704-1801 Sentence denotes FA2H is likely involved in the formation of myelin 2-hydroxy galactosylceramides and -sulfatides.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 394-413 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramides http://www.glycoepitope.jp/epitopes/EP0074
T2 1765-1784 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramides http://www.glycoepitope.jp/epitopes/EP0074

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 1121-1124 Lectin denotes C16 GL_005239

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 356-361 Body_part denotes brain FMA:50801
T2 1202-1212 Body_part denotes Microsomal FMA:67438
T3 1592-1597 Body_part denotes brain FMA:50801
T4 1602-1607 Body_part denotes colon FMA:14543
T5 1608-1615 Body_part denotes tissues FMA:9637

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 356-361 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 1592-1597 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 1602-1607 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 4-9 OrganismTaxon denotes human 9606
T2 516-521 OrganismTaxon denotes human 9606
T3 598-603 OrganismTaxon denotes human 9606
T4 1053-1058 OrganismTaxon denotes human 9606
T5 1652-1657 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 356-361 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T3 380-386 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345
T4 899-912 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T5 990-998 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T8 1592-1597 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T10 1602-1607 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T11 1748-1754 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 356-361 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 1592-1597 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 1602-1607 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526