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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-171 Sentence denotes Correlation of expression of multidrug resistance protein and messenger RNA with 99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma.
TextSentencer_T2 172-176 Sentence denotes AIM:
TextSentencer_T3 177-388 Sentence denotes To explore whether P-glycoprotein (Pgp) and other pumps, multidrug resistance-associated protein (MRP) and lung resistance protein (LRP), could affect tumor accumulation and efflux of 99mTc-MIBI in liver cancer.
TextSentencer_T4 389-397 Sentence denotes METHODS:
TextSentencer_T5 398-470 Sentence denotes Surgically treated 78 liver cancer patients were included in this study.
TextSentencer_T6 471-588 Sentence denotes Before surgery, 99mTc-MIBI SPECT was performed 15 min and 120 min after injection of 20 mCi 99mTc-MIBI, respectively.
TextSentencer_T7 589-679 Sentence denotes Early uptake, delayed uptake (L/Nd), and washout rate (L/Nwr) of 99mTc-MIBI were obtained.
TextSentencer_T8 680-777 Sentence denotes Expressions of Pgp, MRP and LRP were investigated with Western blotting and immunohistochemistry.
TextSentencer_T9 778-850 Sentence denotes Messenger RNA (mRNA) level of Pgp, MRP and LRP was determined by RT-PCR.
TextSentencer_T10 851-859 Sentence denotes RESULTS:
TextSentencer_T11 860-989 Sentence denotes No 99mTc-MIBI uptakes in tumor lesions of 68 of 78 (87.2%) patients with hepatocellular carcinoma were found on 99mTc-MIBI SPECT.
TextSentencer_T12 990-1091 Sentence denotes P-gp expression was observed in tumor tissues of the patients with no uptake of 99mTc-MIBI (P<0.017).
TextSentencer_T13 1092-1229 Sentence denotes No appreciable correlation was found between liver cancer 99mTc-MIBI images and expression of MRP or LRP on the level of protein or mRNA.
TextSentencer_T14 1230-1241 Sentence denotes CONCLUSION:
TextSentencer_T15 1242-1380 Sentence denotes 99mTc-MIBI SPECT is noninvasive, and useful in predicting the presence of MDR1 gene-encoded Pgp in patients with hepatocellular carcinoma.
T1 0-171 Sentence denotes Correlation of expression of multidrug resistance protein and messenger RNA with 99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma.
T2 172-176 Sentence denotes AIM:
T3 177-388 Sentence denotes To explore whether P-glycoprotein (Pgp) and other pumps, multidrug resistance-associated protein (MRP) and lung resistance protein (LRP), could affect tumor accumulation and efflux of 99mTc-MIBI in liver cancer.
T4 389-397 Sentence denotes METHODS:
T5 398-470 Sentence denotes Surgically treated 78 liver cancer patients were included in this study.
T6 471-588 Sentence denotes Before surgery, 99mTc-MIBI SPECT was performed 15 min and 120 min after injection of 20 mCi 99mTc-MIBI, respectively.
T7 589-679 Sentence denotes Early uptake, delayed uptake (L/Nd), and washout rate (L/Nwr) of 99mTc-MIBI were obtained.
T8 680-777 Sentence denotes Expressions of Pgp, MRP and LRP were investigated with Western blotting and immunohistochemistry.
T9 778-850 Sentence denotes Messenger RNA (mRNA) level of Pgp, MRP and LRP was determined by RT-PCR.
T10 851-859 Sentence denotes RESULTS:
T11 860-989 Sentence denotes No 99mTc-MIBI uptakes in tumor lesions of 68 of 78 (87.2%) patients with hepatocellular carcinoma were found on 99mTc-MIBI SPECT.
T12 990-1091 Sentence denotes P-gp expression was observed in tumor tissues of the patients with no uptake of 99mTc-MIBI (P<0.017).
T13 1092-1229 Sentence denotes No appreciable correlation was found between liver cancer 99mTc-MIBI images and expression of MRP or LRP on the level of protein or mRNA.
T14 1230-1241 Sentence denotes CONCLUSION:
T15 1242-1380 Sentence denotes 99mTc-MIBI SPECT is noninvasive, and useful in predicting the presence of MDR1 gene-encoded Pgp in patients with hepatocellular carcinoma.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
15112342-1#19#33#gene5243 196-210 gene5243 denotes P-glycoprotein
15112342-1#35#38#gene5243 212-215 gene5243 denotes Pgp
15112342-1#57#96#gene8714 234-273 gene8714 denotes multidrug resistance-associated protein
15112342-1#198#210#diseaseC0279000 375-387 diseaseC0279000 denotes liver cancer
15112342-1#198#210#diseaseC0345904 375-387 diseaseC0345904 denotes liver cancer
15112342-1#198#210#diseaseC0279000 375-387 diseaseC0279000 denotes liver cancer
15112342-1#198#210#diseaseC0345904 375-387 diseaseC0345904 denotes liver cancer
15112342-1#198#210#diseaseC0279000 375-387 diseaseC0279000 denotes liver cancer
15112342-1#198#210#diseaseC0345904 375-387 diseaseC0345904 denotes liver cancer
15112342-10#74#78#gene5243 1316-1320 gene5243 denotes MDR1
15112342-10#74#78#gene23158 1316-1320 gene23158 denotes MDR1
15112342-10#92#95#gene5243 1334-1337 gene5243 denotes Pgp
15112342-10#113#137#diseaseC2239176 1355-1379 diseaseC2239176 denotes hepatocellular carcinoma
15112342-10#113#137#diseaseC2239176 1355-1379 diseaseC2239176 denotes hepatocellular carcinoma
15112342-9#94#97#gene4363 1186-1189 gene4363 denotes MRP
15112342-9#94#97#gene65108 1186-1189 gene65108 denotes MRP
15112342-9#94#97#gene79971 1186-1189 gene79971 denotes MRP
15112342-9#45#57#diseaseC0279000 1137-1149 diseaseC0279000 denotes liver cancer
15112342-9#45#57#diseaseC0345904 1137-1149 diseaseC0345904 denotes liver cancer
15112342-9#45#57#diseaseC0279000 1137-1149 diseaseC0279000 denotes liver cancer
15112342-9#45#57#diseaseC0345904 1137-1149 diseaseC0345904 denotes liver cancer
15112342-9#45#57#diseaseC0279000 1137-1149 diseaseC0279000 denotes liver cancer
15112342-9#45#57#diseaseC0345904 1137-1149 diseaseC0345904 denotes liver cancer
19#33#gene5243198#210#diseaseC0279000 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0279000 associated_with P-glycoprotein,liver cancer
19#33#gene5243198#210#diseaseC0345904 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0345904 associated_with P-glycoprotein,liver cancer
19#33#gene5243198#210#diseaseC0279000 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0279000 associated_with P-glycoprotein,liver cancer
19#33#gene5243198#210#diseaseC0345904 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0345904 associated_with P-glycoprotein,liver cancer
19#33#gene5243198#210#diseaseC0279000 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0279000 associated_with P-glycoprotein,liver cancer
19#33#gene5243198#210#diseaseC0345904 15112342-1#19#33#gene5243 15112342-1#198#210#diseaseC0345904 associated_with P-glycoprotein,liver cancer
35#38#gene5243198#210#diseaseC0279000 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0279000 associated_with Pgp,liver cancer
35#38#gene5243198#210#diseaseC0345904 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0345904 associated_with Pgp,liver cancer
35#38#gene5243198#210#diseaseC0279000 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0279000 associated_with Pgp,liver cancer
35#38#gene5243198#210#diseaseC0345904 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0345904 associated_with Pgp,liver cancer
35#38#gene5243198#210#diseaseC0279000 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0279000 associated_with Pgp,liver cancer
35#38#gene5243198#210#diseaseC0345904 15112342-1#35#38#gene5243 15112342-1#198#210#diseaseC0345904 associated_with Pgp,liver cancer
57#96#gene8714198#210#diseaseC0279000 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0279000 associated_with multidrug resistance-associated protein,liver cancer
57#96#gene8714198#210#diseaseC0345904 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0345904 associated_with multidrug resistance-associated protein,liver cancer
57#96#gene8714198#210#diseaseC0279000 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0279000 associated_with multidrug resistance-associated protein,liver cancer
57#96#gene8714198#210#diseaseC0345904 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0345904 associated_with multidrug resistance-associated protein,liver cancer
57#96#gene8714198#210#diseaseC0279000 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0279000 associated_with multidrug resistance-associated protein,liver cancer
57#96#gene8714198#210#diseaseC0345904 15112342-1#57#96#gene8714 15112342-1#198#210#diseaseC0345904 associated_with multidrug resistance-associated protein,liver cancer
74#78#gene5243113#137#diseaseC2239176 15112342-10#74#78#gene5243 15112342-10#113#137#diseaseC2239176 associated_with MDR1,hepatocellular carcinoma
74#78#gene5243113#137#diseaseC2239176 15112342-10#74#78#gene5243 15112342-10#113#137#diseaseC2239176 associated_with MDR1,hepatocellular carcinoma
74#78#gene23158113#137#diseaseC2239176 15112342-10#74#78#gene23158 15112342-10#113#137#diseaseC2239176 associated_with MDR1,hepatocellular carcinoma
74#78#gene23158113#137#diseaseC2239176 15112342-10#74#78#gene23158 15112342-10#113#137#diseaseC2239176 associated_with MDR1,hepatocellular carcinoma
92#95#gene5243113#137#diseaseC2239176 15112342-10#92#95#gene5243 15112342-10#113#137#diseaseC2239176 associated_with Pgp,hepatocellular carcinoma
92#95#gene5243113#137#diseaseC2239176 15112342-10#92#95#gene5243 15112342-10#113#137#diseaseC2239176 associated_with Pgp,hepatocellular carcinoma
94#97#gene436345#57#diseaseC0279000 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene436345#57#diseaseC0345904 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene436345#57#diseaseC0279000 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene436345#57#diseaseC0345904 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene436345#57#diseaseC0279000 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene436345#57#diseaseC0345904 15112342-9#94#97#gene4363 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0279000 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0345904 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0279000 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0345904 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0279000 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene6510845#57#diseaseC0345904 15112342-9#94#97#gene65108 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0279000 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0345904 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0279000 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0345904 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0279000 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0279000 associated_with MRP,liver cancer
94#97#gene7997145#57#diseaseC0345904 15112342-9#94#97#gene79971 15112342-9#45#57#diseaseC0345904 associated_with MRP,liver cancer

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1028-1035 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 375-380 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 420-425 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T4 1137-1142 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T5 284-288 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2497 1316-1320 gene:5243 denotes MDR1
T2498 1355-1379 disease:C2239176 denotes hepatocellular carcinoma
R1 T2497 T2498 associated_with MDR1,hepatocellular carcinoma
R2 T2497 T2498 associated_with MDR1,hepatocellular carcinoma

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 284-288 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 375-380 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 420-425 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T4 1137-1142 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T5 1028-1035 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

DisGeNET

Id Subject Object Predicate Lexical cue
T0 234-273 gene:8714 denotes multidrug resistance-associated protein
T1 375-387 disease:C0279000 denotes liver cancer
T2 234-273 gene:8714 denotes multidrug resistance-associated protein
T3 375-387 disease:C0345904 denotes liver cancer
T4 275-278 gene:65108 denotes MRP
T5 375-387 disease:C0279000 denotes liver cancer
T6 275-278 gene:65108 denotes MRP
T7 375-387 disease:C0345904 denotes liver cancer
T8 275-278 gene:79971 denotes MRP
T9 375-387 disease:C0279000 denotes liver cancer
T10 275-278 gene:79971 denotes MRP
T11 375-387 disease:C0345904 denotes liver cancer
T12 275-278 gene:4363 denotes MRP
T13 375-387 disease:C0279000 denotes liver cancer
T14 275-278 gene:4363 denotes MRP
T15 375-387 disease:C0345904 denotes liver cancer
R1 T0 T1 associated_with multidrug resistance-associated protein,liver cancer
R2 T2 T3 associated_with multidrug resistance-associated protein,liver cancer
R3 T4 T5 associated_with MRP,liver cancer
R4 T6 T7 associated_with MRP,liver cancer
R5 T8 T9 associated_with MRP,liver cancer
R6 T10 T11 associated_with MRP,liver cancer
R7 T12 T13 associated_with MRP,liver cancer
R8 T14 T15 associated_with MRP,liver cancer