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PubMed:15067898 / 178-187 JSONTXT

[Ultrasonographic features of orofacial clefts at first trimester of pregnancy: report of two cases]. Aspects échographiques de fentes labio-palatines au premier trimestre de la grossesse. A propos de deux cas. Fetal cleft lip and palate are now routinely diagnosed by prenatal ultrasound in the late first and second trimester of pregnancy. We report two cases of bilateral orofacial cleft diagnosed at 10 and 12.5 weeks of gestation by ultrasound. Ultrasound can replace invasive embryoscopy for the early diagnosis of facial cleft, based on specific sonographic signs in high risk patients.

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