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PubMed:15046742 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-78 Sentence denotes Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene.
TextSentencer_T2 79-152 Sentence denotes Genetics and diet interact to cause type 2 diabetes mellitus and obesity.
TextSentencer_T3 153-240 Sentence denotes PCK1 has been implicated as one of many genes associated with type 2 diabetes mellitus.
TextSentencer_T4 241-358 Sentence denotes The common assumption is that mutations in PCK1 lead to excessive glucose production through hepatic gluconeogenesis.
TextSentencer_T5 359-500 Sentence denotes However, there is an alternative explanation, wherein mutations at the PCK1 locus could selectively affect PCK1 expression in adipose tissue.
TextSentencer_T6 501-607 Sentence denotes The result would be changes in glyceroneogenesis that would affect the storage and release of fatty acids.
TextSentencer_T7 608-758 Sentence denotes Here, we present the novel hypothesis that a variety of phenotypes could arise from mutations of the various tissue-specific control elements of PCK1.
TextSentencer_T8 759-903 Sentence denotes We also suggest specific quantitative metabolic traits that would accompany mutations that selectively affect PCK1 expression in adipose tissue.
T1 0-78 Sentence denotes Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene.
T2 79-152 Sentence denotes Genetics and diet interact to cause type 2 diabetes mellitus and obesity.
T3 153-240 Sentence denotes PCK1 has been implicated as one of many genes associated with type 2 diabetes mellitus.
T4 241-358 Sentence denotes The common assumption is that mutations in PCK1 lead to excessive glucose production through hepatic gluconeogenesis.
T5 359-500 Sentence denotes However, there is an alternative explanation, wherein mutations at the PCK1 locus could selectively affect PCK1 expression in adipose tissue.
T6 501-607 Sentence denotes The result would be changes in glyceroneogenesis that would affect the storage and release of fatty acids.
T7 608-758 Sentence denotes Here, we present the novel hypothesis that a variety of phenotypes could arise from mutations of the various tissue-specific control elements of PCK1.
T8 759-903 Sentence denotes We also suggest specific quantitative metabolic traits that would accompany mutations that selectively affect PCK1 expression in adipose tissue.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
15046742-0#32#36#gene5105 32-36 gene5105 denotes PCK1
15046742-0#52#60#diseaseC0011847 52-60 diseaseC0011847 denotes diabetes
15046742-0#52#60#diseaseC0011849 52-60 diseaseC0011849 denotes diabetes
15046742-2#0#4#gene5105 153-157 gene5105 denotes PCK1
15046742-2#62#86#diseaseC0011860 215-239 diseaseC0011860 denotes type 2 diabetes mellitus
32#36#gene510552#60#diseaseC0011847 15046742-0#32#36#gene5105 15046742-0#52#60#diseaseC0011847 associated_with PCK1,diabetes
32#36#gene510552#60#diseaseC0011849 15046742-0#32#36#gene5105 15046742-0#52#60#diseaseC0011849 associated_with PCK1,diabetes
0#4#gene510562#86#diseaseC0011860 15046742-2#0#4#gene5105 15046742-2#62#86#diseaseC0011860 associated_with PCK1,type 2 diabetes mellitus

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T921 32-36 gene:5105 denotes PCK1
T922 52-60 disease:C0011847 denotes diabetes
R1 T921 T922 associated_with PCK1,diabetes
R2 T921 T922 associated_with PCK1,diabetes

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 485-499 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose tissue
PD-UBERON-AE-B_T2 888-902 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose tissue
PD-UBERON-AE-B_T3 493-499 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T4 717-723 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T5 896-902 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 493-499 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T2 717-723 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T3 896-902 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T4 485-499 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose tissue
PD-UBERON-AE-B_T5 888-902 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose tissue

DisGeNET

Id Subject Object Predicate Lexical cue
T0 153-157 gene:5105 denotes PCK1
T1 215-239 disease:C0011860 denotes type 2 diabetes mellitus
R1 T0 T1 associated_with PCK1,type 2 diabetes mellitus