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PubMed:1502202 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-10 protein denotes NF-kappa B
T2 38-48 protein denotes NF-kappa B
T3 49-74 DNA denotes p50 subunit gene promoter
T4 152-167 cell_type denotes monocytic cells
T5 244-254 protein denotes NF-kappa B
T6 267-287 cell_line denotes U937 monocytic cells
T7 383-391 DNA denotes promoter
T8 424-438 protein denotes p105 precursor
T9 446-468 protein denotes NF-kappa B p50 subunit
T10 516-524 DNA denotes promoter
T11 607-625 DNA denotes AP-1-binding motif
T12 640-660 protein denotes p50/p65 heterodimers
T13 708-718 protein denotes NF-kappa B
T14 744-762 cell_type denotes HIV-infected cells
T15 793-803 protein denotes NF-kappa B
T16 855-865 protein denotes NF-kappa B
T17 926-955 protein denotes PKC isoenzymes alpha and beta
T18 1079-1089 cell_line denotes U937 cells
T19 1102-1112 protein denotes NF-kappa B
T20 1114-1121 protein denotes p50/p65
T21 1201-1211 protein denotes NF-kappa B
T22 1326-1336 protein denotes NF-kappa B

GENIAcorpus

Id Subject Object Predicate Lexical cue
T14 457-460 protein_subunit denotes p50
T1 0-10 protein_molecule denotes NF-kappa B
T2 38-48 protein_molecule denotes NF-kappa B
T3 49-52 protein_subunit denotes p50
T4 106-134 virus denotes human immunodeficiency virus
T5 152-167 cell_type denotes monocytic cells
T6 244-254 protein_molecule denotes NF-kappa B
T7 267-271 cell_line denotes U937
T8 272-287 cell_type denotes monocytic cells
T9 314-342 virus denotes human immunodeficiency virus
T10 344-347 virus denotes HIV
T11 383-391 DNA_domain_or_region denotes promoter
T12 424-438 protein_molecule denotes p105 precursor
T13 446-456 protein_subunit denotes NF-kappa B
T15 516-524 DNA_domain_or_region denotes promoter
T16 583-594 DNA_substructure denotes NF-kappa B-
T17 607-625 DNA_domain_or_region denotes AP-1-binding motif
T18 640-660 protein_complex denotes p50/p65 heterodimers
T19 708-718 protein_molecule denotes NF-kappa B
T20 744-747 virus denotes HIV
T21 793-803 protein_molecule denotes NF-kappa B
T22 826-839 other_organic_compound denotes phorbol ester
T23 855-865 protein_molecule denotes NF-kappa B
T24 891-894 virus denotes HIV
T25 926-955 protein_molecule denotes PKC isoenzymes alpha and beta
T26 981-999 other_organic_compound denotes specific inhibitor
T27 1001-1011 other_organic_compound denotes GF 109203X
T28 1062-1065 virus denotes HIV
T29 1079-1089 cell_line denotes U937 cells
T30 1102-1112 protein_molecule denotes NF-kappa B
T31 1114-1121 protein_molecule denotes p50/p65
T32 1148-1161 DNA_substructure denotes p105 promoter
T33 1201-1211 protein_molecule denotes NF-kappa B
T34 1264-1267 virus denotes HIV
T35 1326-1336 protein_molecule denotes NF-kappa B

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 38-48 NP denotes NF-kappa B
C1 34-74 NP denotes the NF-kappa B p50 subunit gene promoter
C3 106-134 NP denotes human immunodeficiency virus
C4 152-167 NP denotes monocytic cells
C6 244-254 NP denotes NF-kappa B
C8 314-348 NP denotes human immunodeficiency virus (HIV)
C7 267-348 NP denotes U937 monocytic cells chronically infected with human immunodeficiency virus (HIV)
C5 169-348 NP denotes The molecular mechanisms underlying the sustained nuclear translocation of NF-kappa B observed in U937 monocytic cells chronically infected with human immunodeficiency virus (HIV)
C10 446-456 NP denotes NF-kappa B
C9 379-468 NP denotes the promoter regulating the synthesis of the p105 precursor of the NF-kappa B p50 subunit
C11 485-496 NP denotes these cells
C12 511-524 NP denotes this promoter
C13 583-593 NP denotes NF-kappa B
C14 708-718 NP denotes NF-kappa B
C15 744-762 NP denotes HIV-infected cells
C16 793-803 NP denotes NF-kappa B
C18 855-865 NP denotes NF-kappa B
C20 891-894 NP denotes HIV
C19 891-904 NP denotes HIV infection
C17 841-904 NP denotes the permanent NF-kappa B translocation induced by HIV infection
C22 1062-1065 NP denotes HIV
C23 1079-1089 NP denotes U937 cells
C21 1054-1089 NP denotes chronic HIV infection of U937 cells
C25 1102-1112 NP denotes NF-kappa B
C24 1091-1136 NP denotes continuous NF-kappa B (p50/p65) translocation
C26 1201-1211 NP denotes NF-kappa B
C27 1259-1286 NP denotes This HIV-mediated mechanism
C28 1326-1336 NP denotes NF-kappa B
R1 C6 C2 coref-ident NF-kappa B,NF-kappa B
R2 C8 C3 coref-ident human immunodeficiency virus (HIV),human immunodeficiency virus
R3 C7 C4 coref-other U937 monocytic cells chronically infected with human immunodeficiency virus (HIV),monocytic cells
R4 C10 C6 coref-ident NF-kappa B,NF-kappa B
R5 C9 C1 coref-ident the promoter regulating the synthesis of the p105 precursor of the NF-kappa B p50 subunit,the NF-kappa B p50 subunit gene promoter
R6 C11 C7 coref-ident these cells,U937 monocytic cells chronically infected with human immunodeficiency virus (HIV)
R7 C12 C9 coref-ident this promoter,the promoter regulating the synthesis of the p105 precursor of the NF-kappa B p50 subunit
R8 C13 C10 coref-ident NF-kappa B,NF-kappa B
R9 C14 C13 coref-ident NF-kappa B,NF-kappa B
R10 C15 C11 coref-other HIV-infected cells,these cells
R11 C16 C14 coref-ident NF-kappa B,NF-kappa B
R12 C18 C16 coref-ident NF-kappa B,NF-kappa B
R13 C20 C8 coref-ident HIV,human immunodeficiency virus (HIV)
R14 C22 C20 coref-ident HIV,HIV
R15 C23 C11 coref-other U937 cells,these cells
R16 C21 C19 coref-other chronic HIV infection of U937 cells,HIV infection
R17 C25 C18 coref-ident NF-kappa B,NF-kappa B
R18 C24 C17 coref-other continuous NF-kappa B (p50/p65) translocation,the permanent NF-kappa B translocation induced by HIV infection
R19 C26 C25 coref-ident NF-kappa B,NF-kappa B
R20 C27 C5 coref-other This HIV-mediated mechanism,The molecular mechanisms underlying the sustained nuclear translocation of NF-kappa B observed in U937 monocytic cells chronically infected with human immunodeficiency virus (HIV)
R21 C28 C26 coref-ident NF-kappa B,NF-kappa B

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-168 Sentence denotes NF-kappa B-dependent induction of the NF-kappa B p50 subunit gene promoter underlies self-perpetuation of human immunodeficiency virus transcription in monocytic cells.
S2 169-362 Sentence denotes The molecular mechanisms underlying the sustained nuclear translocation of NF-kappa B observed in U937 monocytic cells chronically infected with human immunodeficiency virus (HIV) were studied.
S3 363-497 Sentence denotes The activity of the promoter regulating the synthesis of the p105 precursor of the NF-kappa B p50 subunit was enhanced in these cells.
S4 498-661 Sentence denotes Deletions in this promoter indicated that this upregulation was mediated through the NF-kappa B- but not the AP-1-binding motif, by bona fide p50/p65 heterodimers.
S5 662-763 Sentence denotes Analysis of cytosolic extracts indicated that NF-kappa B levels were increased in HIV-infected cells.
S6 764-1013 Sentence denotes In contrast to the transient NF-kappa B activation induced by phorbol ester, the permanent NF-kappa B translocation induced by HIV infection was not dependent on PKC isoenzymes alpha and beta as shown by the use of a specific inhibitor (GF 109203X).
S7 1014-1258 Sentence denotes These observations indicate that during chronic HIV infection of U937 cells, continuous NF-kappa B (p50/p65) translocation results in p105 promoter upregulation with subsequent cytosolic NF-kappa B accumulation, ready for further translocation.
S8 1259-1348 Sentence denotes This HIV-mediated mechanism results in a self-perpetuating loop of NF-kappa B production.