PubMed:14736728
Annnotations
GlyCosmos6-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 553-566 | Body_part | denotes | intracellular | http://purl.obolibrary.org/obo/GO_0005622 |
T2 | 964-969 | Body_part | denotes | Golgi | http://purl.obolibrary.org/obo/GO_0005794 |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
PD-MONDO-B_T1 | 113-158 | http://purl.obolibrary.org/obo/MONDO_0015674 | denotes | Late infantile neuronal ceroid lipofuscinosis | |
PD-MONDO-B_T2 | 113-158 | http://purl.obolibrary.org/obo/MONDO_0008769 | denotes | Late infantile neuronal ceroid lipofuscinosis | |
PD-MONDO-B_T3 | 118-158 | http://purl.obolibrary.org/obo/MONDO_0019261 | denotes | infantile neuronal ceroid lipofuscinosis | |
PD-MONDO-B_T4 | 118-158 | http://purl.obolibrary.org/obo/MONDO_0009744 | denotes | infantile neuronal ceroid lipofuscinosis | |
PD-MONDO-B_T5 | 128-158 | http://purl.obolibrary.org/obo/MONDO_0016295 | denotes | neuronal ceroid lipofuscinosis | |
PD-MONDO-B_T6 | 160-165 | http://purl.obolibrary.org/obo/MONDO_0015674 | denotes | LINCL | |
PD-MONDO-B_T7 | 160-165 | http://purl.obolibrary.org/obo/MONDO_0008769 | denotes | LINCL | |
PD-MONDO-B_T8 | 283-288 | http://purl.obolibrary.org/obo/MONDO_0015674 | denotes | LINCL | |
PD-MONDO-B_T9 | 283-288 | http://purl.obolibrary.org/obo/MONDO_0008769 | denotes | LINCL | |
T1 | 113-158 | Disease | denotes | Late infantile neuronal ceroid lipofuscinosis | http://purl.obolibrary.org/obo/MONDO_0008769|http://purl.obolibrary.org/obo/MONDO_0015674 |
GlyCosmos600-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 202-211 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomal |
T2 | 658-664 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | HEK293 |
T3 | 665-670 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T4 | 870-875 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GlyCosmos6-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 103-111 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T2 | 202-211 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomal |
T3 | 543-551 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T4 | 658-664 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | HEK293 |
T5 | 665-670 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T6 | 870-875 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 128-158 | http://purl.bioontology.org/ontology/ICD10/E75.4 | denotes | neuronal ceroid lipofuscinosis |
GlycoBiology-FMA
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
_T1 | 29-39 | FMAID:82750 | denotes | asparagine |
_T2 | 29-39 | FMAID:196739 | denotes | asparagine |
_T3 | 66-73 | FMAID:67257 | denotes | protein |
_T4 | 66-73 | FMAID:165447 | denotes | protein |
_T5 | 128-136 | FMAID:166033 | denotes | neuronal |
_T6 | 128-136 | FMAID:54527 | denotes | neuronal |
_T7 | 128-136 | FMAID:150783 | denotes | neuronal |
_T8 | 202-211 | FMAID:63836 | denotes | lysosomal |
_T9 | 202-211 | FMAID:162299 | denotes | lysosomal |
_T10 | 608-615 | FMAID:67257 | denotes | protein |
_T11 | 608-615 | FMAID:165447 | denotes | protein |
_T12 | 665-670 | FMAID:169002 | denotes | cells |
_T13 | 665-670 | FMAID:68646 | denotes | cells |
_T14 | 870-875 | FMAID:68646 | denotes | cells |
_T15 | 870-875 | FMAID:169002 | denotes | cells |
_T16 | 881-885 | FMAID:217859 | denotes | rate |
_T17 | 1016-1023 | FMAID:67257 | denotes | protein |
_T18 | 1016-1023 | FMAID:165447 | denotes | protein |
_T19 | 1174-1181 | FMAID:67257 | denotes | protein |
_T20 | 1174-1181 | FMAID:165447 | denotes | protein |
_T21 | 1328-1343 | FMAID:82742 | denotes | oligosaccharide |
_T22 | 1328-1343 | FMAID:196731 | denotes | oligosaccharide |
uniprot-human
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 212-235 | http://www.uniprot.org/uniprot/O14773 | denotes | tripeptidyl peptidase-I |
uniprot-mouse
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 212-235 | http://www.uniprot.org/uniprot/O89023 | denotes | tripeptidyl peptidase-I |
GlycoBiology-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 113-117 | http://purl.bioontology.org/ontology/NCBITAXON/8186 | denotes | Late |
T2 | 665-670 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T3 | 870-875 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T4 | 1029-1044 | http://purl.bioontology.org/ontology/NCBITAXON/8004 | denotes | electrophoretic |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-112 | Sentence | denotes | Mutation of the glycosylated asparagine residue 286 in human CLN2 protein results in loss of enzymatic activity. |
TextSentencer_T2 | 113-252 | Sentence | denotes | Late infantile neuronal ceroid lipofuscinosis (LINCL) is caused by the deficiency of the lysosomal tripeptidyl peptidase-I encoded by CLN2. |
TextSentencer_T3 | 253-389 | Sentence | denotes | We previously detected in two LINCL patients a homozygous missense mutation, p.Asn286Ser, that affects a potential N-glycosylation site. |
TextSentencer_T4 | 390-616 | Sentence | denotes | We introduced the p.Asn286Ser mutation into the wild-type CLN2 cDNA and performed transient expression analysis to determine the effect on the catalytic activity, intracellular targeting, and glycosylation of the CLN2 protein. |
TextSentencer_T5 | 617-723 | Sentence | denotes | Expression of mutant p.Asn286Ser CLN2 in HEK293 cells revealed that the mutant was enzymatically inactive. |
TextSentencer_T6 | 724-876 | Sentence | denotes | Western blot analysis demonstrated that at steady state the amounts of expressed p.Asn286Ser CLN2 were reduced compared with wild-type expressing cells. |
TextSentencer_T7 | 877-1024 | Sentence | denotes | The rate of synthesis and the sorting of the newly synthesized p.Asn286Ser CLN2 in the Golgi was not affected compared with wild-type CLN2 protein. |
TextSentencer_T8 | 1025-1271 | Sentence | denotes | The electrophoretic mobility of the immunoprecipitated mutant p.Asn286Ser CLN2 was increased by approximately 2 kDa compared with the wild-type CLN2 protein, whereas deglycosylation led to the generation of polypeptides of the same apparent size. |
TextSentencer_T9 | 1272-1386 | Sentence | denotes | The data suggest that mutant p.Asn286Ser CLN2 lacks one oligosaccharide chain resulting in enzymatic inactivation. |
T1 | 0-112 | Sentence | denotes | Mutation of the glycosylated asparagine residue 286 in human CLN2 protein results in loss of enzymatic activity. |
T2 | 113-252 | Sentence | denotes | Late infantile neuronal ceroid lipofuscinosis (LINCL) is caused by the deficiency of the lysosomal tripeptidyl peptidase-I encoded by CLN2. |
T3 | 253-389 | Sentence | denotes | We previously detected in two LINCL patients a homozygous missense mutation, p.Asn286Ser, that affects a potential N-glycosylation site. |
T4 | 390-616 | Sentence | denotes | We introduced the p.Asn286Ser mutation into the wild-type CLN2 cDNA and performed transient expression analysis to determine the effect on the catalytic activity, intracellular targeting, and glycosylation of the CLN2 protein. |
T5 | 617-723 | Sentence | denotes | Expression of mutant p.Asn286Ser CLN2 in HEK293 cells revealed that the mutant was enzymatically inactive. |
T6 | 724-876 | Sentence | denotes | Western blot analysis demonstrated that at steady state the amounts of expressed p.Asn286Ser CLN2 were reduced compared with wild-type expressing cells. |
T7 | 877-1024 | Sentence | denotes | The rate of synthesis and the sorting of the newly synthesized p.Asn286Ser CLN2 in the Golgi was not affected compared with wild-type CLN2 protein. |
T8 | 1025-1271 | Sentence | denotes | The electrophoretic mobility of the immunoprecipitated mutant p.Asn286Ser CLN2 was increased by approximately 2 kDa compared with the wild-type CLN2 protein, whereas deglycosylation led to the generation of polypeptides of the same apparent size. |
T9 | 1272-1386 | Sentence | denotes | The data suggest that mutant p.Asn286Ser CLN2 lacks one oligosaccharide chain resulting in enzymatic inactivation. |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 16-28 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylated |
T2 | 370-383 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T3 | 582-595 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T4 | 533-551 | http://purl.obolibrary.org/obo/GO_0003824 | denotes | catalytic activity |
T5 | 889-898 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 202-211 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomal |
T2 | 553-566 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
T3 | 665-670 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T4 | 870-875 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5 | 964-969 | http://purl.obolibrary.org/obo/GO_0005794 | denotes | Golgi |
EDAM-topics
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-8 | http://edamontology.org/topic_0199 | denotes | Mutation |
T2 | 55-60 | http://edamontology.org/topic_2815 | denotes | human |
T3 | 66-73 | http://edamontology.org/topic_0078 | denotes | protein |
T4 | 202-211 | http://edamontology.org/topic_0616 | denotes | lysosomal |
T5 | 320-328 | http://edamontology.org/topic_0199 | denotes | mutation |
T6 | 420-428 | http://edamontology.org/topic_0199 | denotes | mutation |
T7 | 453-457 | http://edamontology.org/topic_3512 | denotes | cDNA |
T8 | 567-576 | http://edamontology.org/topic_0154 | denotes | targeting |
T9 | 608-615 | http://edamontology.org/topic_0078 | denotes | protein |
T10 | 1016-1023 | http://edamontology.org/topic_0078 | denotes | protein |
T11 | 1061-1079 | http://edamontology.org/topic_3557 | denotes | immunoprecipitated |
T12 | 1174-1181 | http://edamontology.org/topic_0078 | denotes | protein |
EDAM-DFO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 40-47 | http://edamontology.org/data_1756 | denotes | residue |
T2 | 66-73 | http://edamontology.org/data_1467 | denotes | protein |
T3 | 66-73 | http://edamontology.org/format_1208 | denotes | protein |
T4 | 267-275 | http://edamontology.org/operation_2423 | denotes | detected |
T5 | 482-501 | http://edamontology.org/operation_2410 | denotes | expression analysis |
T6 | 482-501 | http://edamontology.org/operation_2495 | denotes | expression analysis |
T7 | 493-501 | http://edamontology.org/operation_2945 | denotes | analysis |
T8 | 608-615 | http://edamontology.org/data_1467 | denotes | protein |
T9 | 608-615 | http://edamontology.org/format_1208 | denotes | protein |
T10 | 737-745 | http://edamontology.org/operation_2945 | denotes | analysis |
T11 | 746-758 | http://edamontology.org/operation_2246 | denotes | demonstrated |
T12 | 1016-1023 | http://edamontology.org/format_1208 | denotes | protein |
T13 | 1016-1023 | http://edamontology.org/data_1467 | denotes | protein |
T14 | 1174-1181 | http://edamontology.org/format_1208 | denotes | protein |
T15 | 1174-1181 | http://edamontology.org/data_1467 | denotes | protein |
T16 | 1218-1228 | http://edamontology.org/operation_3429 | denotes | generation |
T17 | 1276-1280 | http://edamontology.org/data_0006 | denotes | data |
GlyCosmos600-FMA
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-FMA-PAE-B_T1 | 66-73 | http://purl.org/sig/ont/fma/fma67257 | denotes | protein |
PD-FMA-PAE-B_T2 | 128-136 | http://purl.org/sig/ont/fma/fma54527 | denotes | neuronal |
PD-FMA-PAE-B_T3 | 202-211 | http://purl.org/sig/ont/fma/fma63836 | denotes | lysosomal |
PD-FMA-PAE-B_T4 | 608-615 | http://purl.org/sig/ont/fma/fma67257 | denotes | protein |
PD-FMA-PAE-B_T5 | 665-670 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
PD-FMA-PAE-B_T6 | 870-875 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
PD-FMA-PAE-B_T7 | 1016-1023 | http://purl.org/sig/ont/fma/fma67257 | denotes | protein |
PD-FMA-PAE-B_T8 | 1174-1181 | http://purl.org/sig/ont/fma/fma67257 | denotes | protein |
PD-FMA-PAE-B_T9 | 1328-1343 | http://purl.org/sig/ont/fma/fma82742 | denotes | oligosaccharide |
DisGeNET5_gene_disease
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
14736728-1#99#122#gene1200 | 212-235 | gene1200 | denotes | tripeptidyl peptidase-I |
14736728-1#134#138#gene1200 | 247-251 | gene1200 | denotes | CLN2 |
14736728-1#0#45#diseaseC0022340 | 113-158 | diseaseC0022340 | denotes | Late infantile neuronal ceroid lipofuscinosis |
14736728-1#47#52#diseaseC0022340 | 160-165 | diseaseC0022340 | denotes | LINCL |
14736728-1#0#45#diseaseC0022340 | 113-158 | diseaseC0022340 | denotes | Late infantile neuronal ceroid lipofuscinosis |
14736728-1#47#52#diseaseC0022340 | 160-165 | diseaseC0022340 | denotes | LINCL |
99#122#gene12000#45#diseaseC0022340 | 14736728-1#99#122#gene1200 | 14736728-1#0#45#diseaseC0022340 | associated_with | tripeptidyl peptidase-I,Late infantile neuronal ceroid lipofuscinosis |
99#122#gene120047#52#diseaseC0022340 | 14736728-1#99#122#gene1200 | 14736728-1#47#52#diseaseC0022340 | associated_with | tripeptidyl peptidase-I,LINCL |
99#122#gene12000#45#diseaseC0022340 | 14736728-1#99#122#gene1200 | 14736728-1#0#45#diseaseC0022340 | associated_with | tripeptidyl peptidase-I,Late infantile neuronal ceroid lipofuscinosis |
99#122#gene120047#52#diseaseC0022340 | 14736728-1#99#122#gene1200 | 14736728-1#47#52#diseaseC0022340 | associated_with | tripeptidyl peptidase-I,LINCL |
134#138#gene12000#45#diseaseC0022340 | 14736728-1#134#138#gene1200 | 14736728-1#0#45#diseaseC0022340 | associated_with | CLN2,Late infantile neuronal ceroid lipofuscinosis |
134#138#gene120047#52#diseaseC0022340 | 14736728-1#134#138#gene1200 | 14736728-1#47#52#diseaseC0022340 | associated_with | CLN2,LINCL |
134#138#gene12000#45#diseaseC0022340 | 14736728-1#134#138#gene1200 | 14736728-1#0#45#diseaseC0022340 | associated_with | CLN2,Late infantile neuronal ceroid lipofuscinosis |
134#138#gene120047#52#diseaseC0022340 | 14736728-1#134#138#gene1200 | 14736728-1#47#52#diseaseC0022340 | associated_with | CLN2,LINCL |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 55-60 | OrganismTaxon | denotes | human | NCBItxid:9606 |
pubmed-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
EnjuParser_T0 | 0-8 | NN | denotes | Mutation |
EnjuParser_T1 | 9-11 | IN | denotes | of |
EnjuParser_T2 | 12-15 | DT | denotes | the |
EnjuParser_T3 | 16-28 | VBN | denotes | glycosylated |
EnjuParser_T4 | 29-39 | NN | denotes | asparagine |
EnjuParser_T5 | 40-47 | NN | denotes | residue |
EnjuParser_T6 | 48-51 | CD | denotes | 286 |
EnjuParser_T7 | 52-54 | IN | denotes | in |
EnjuParser_T8 | 55-60 | JJ | denotes | human |
EnjuParser_T9 | 61-65 | NN | denotes | CLN2 |
EnjuParser_T10 | 66-73 | NN | denotes | protein |
EnjuParser_T11 | 74-81 | VBZ | denotes | results |
EnjuParser_T12 | 82-84 | IN | denotes | in |
EnjuParser_T13 | 85-89 | NN | denotes | loss |
EnjuParser_T14 | 90-92 | IN | denotes | of |
EnjuParser_T15 | 93-102 | JJ | denotes | enzymatic |
EnjuParser_T16 | 103-111 | NN | denotes | activity |
EnjuParser_T17 | 113-117 | JJ | denotes | Late |
EnjuParser_T18 | 118-127 | JJ | denotes | infantile |
EnjuParser_T19 | 128-136 | JJ | denotes | neuronal |
EnjuParser_T20 | 137-143 | NN | denotes | ceroid |
EnjuParser_T21 | 144-158 | NN | denotes | lipofuscinosis |
EnjuParser_T22 | 159-160 | -LRB- | denotes | ( |
EnjuParser_T23 | 160-165 | NN | denotes | LINCL |
EnjuParser_T24 | 165-166 | -RRB- | denotes | ) |
EnjuParser_T25 | 167-169 | VBZ | denotes | is |
EnjuParser_T26 | 170-176 | VBN | denotes | caused |
EnjuParser_T27 | 177-179 | IN | denotes | by |
EnjuParser_T28 | 180-183 | DT | denotes | the |
EnjuParser_T29 | 184-194 | NN | denotes | deficiency |
EnjuParser_T30 | 195-197 | IN | denotes | of |
EnjuParser_T31 | 198-201 | DT | denotes | the |
EnjuParser_T32 | 202-211 | JJ | denotes | lysosomal |
EnjuParser_T33 | 212-223 | NN | denotes | tripeptidyl |
EnjuParser_T34 | 224-235 | NN | denotes | peptidase-I |
EnjuParser_T35 | 236-243 | VBN | denotes | encoded |
EnjuParser_T36 | 244-246 | IN | denotes | by |
EnjuParser_T37 | 247-251 | NN | denotes | CLN2 |
EnjuParser_T38 | 253-255 | PRP | denotes | We |
EnjuParser_T39 | 256-266 | RB | denotes | previously |
EnjuParser_T40 | 267-275 | VBN | denotes | detected |
EnjuParser_T41 | 276-278 | IN | denotes | in |
EnjuParser_T42 | 279-282 | CD | denotes | two |
EnjuParser_T43 | 283-288 | NN | denotes | LINCL |
EnjuParser_T44 | 289-297 | NNS | denotes | patients |
EnjuParser_T45 | 298-299 | DT | denotes | a |
EnjuParser_T46 | 300-310 | JJ | denotes | homozygous |
EnjuParser_T47 | 311-319 | JJ | denotes | missense |
EnjuParser_T48 | 320-328 | NN | denotes | mutation |
EnjuParser_T49 | 328-329 | -COMMA- | denotes | , |
EnjuParser_T50 | 330-341 | NN | denotes | p.Asn286Ser |
EnjuParser_T51 | 341-342 | -COMMA- | denotes | , |
EnjuParser_T52 | 343-347 | WDT | denotes | that |
EnjuParser_T53 | 348-355 | VBZ | denotes | affects |
EnjuParser_T54 | 356-357 | DT | denotes | a |
EnjuParser_T55 | 358-367 | JJ | denotes | potential |
EnjuParser_T56 | 368-383 | NN | denotes | N-glycosylation |
EnjuParser_T57 | 384-388 | NN | denotes | site |
EnjuParser_T58 | 390-392 | PRP | denotes | We |
EnjuParser_T59 | 393-403 | VBD | denotes | introduced |
EnjuParser_T60 | 404-407 | DT | denotes | the |
EnjuParser_T61 | 408-419 | NN | denotes | p.Asn286Ser |
EnjuParser_T62 | 420-428 | NN | denotes | mutation |
EnjuParser_T63 | 429-433 | IN | denotes | into |
EnjuParser_T64 | 434-437 | DT | denotes | the |
EnjuParser_T65 | 438-447 | JJ | denotes | wild-type |
EnjuParser_T66 | 448-452 | NN | denotes | CLN2 |
EnjuParser_T67 | 453-457 | NN | denotes | cDNA |
EnjuParser_T68 | 458-461 | CC | denotes | and |
EnjuParser_T69 | 462-471 | VBD | denotes | performed |
EnjuParser_T70 | 472-481 | JJ | denotes | transient |
EnjuParser_T71 | 482-492 | NN | denotes | expression |
EnjuParser_T72 | 493-501 | NN | denotes | analysis |
EnjuParser_T73 | 502-504 | TO | denotes | to |
EnjuParser_T74 | 505-514 | VB | denotes | determine |
EnjuParser_T75 | 515-518 | DT | denotes | the |
EnjuParser_T76 | 519-525 | NN | denotes | effect |
EnjuParser_T77 | 526-528 | IN | denotes | on |
EnjuParser_T78 | 529-532 | DT | denotes | the |
EnjuParser_T79 | 533-542 | JJ | denotes | catalytic |
EnjuParser_T80 | 543-551 | NN | denotes | activity |
EnjuParser_T81 | 551-552 | -COMMA- | denotes | , |
EnjuParser_T82 | 553-566 | JJ | denotes | intracellular |
EnjuParser_T83 | 567-576 | NN | denotes | targeting |
EnjuParser_T84 | 576-577 | -COMMA- | denotes | , |
EnjuParser_T85 | 578-581 | CC | denotes | and |
EnjuParser_T86 | 582-595 | NN | denotes | glycosylation |
EnjuParser_T87 | 596-598 | IN | denotes | of |
EnjuParser_T88 | 599-602 | DT | denotes | the |
EnjuParser_T89 | 603-607 | NN | denotes | CLN2 |
EnjuParser_T90 | 608-615 | NN | denotes | protein |
EnjuParser_T91 | 617-627 | NN | denotes | Expression |
EnjuParser_T92 | 628-630 | IN | denotes | of |
EnjuParser_T93 | 631-637 | JJ | denotes | mutant |
EnjuParser_T94 | 638-649 | NN | denotes | p.Asn286Ser |
EnjuParser_T95 | 650-654 | NN | denotes | CLN2 |
EnjuParser_T96 | 655-657 | IN | denotes | in |
EnjuParser_T97 | 658-664 | NN | denotes | HEK293 |
EnjuParser_T98 | 665-670 | NNS | denotes | cells |
EnjuParser_T99 | 671-679 | VBD | denotes | revealed |
EnjuParser_T100 | 680-684 | IN | denotes | that |
EnjuParser_T101 | 685-688 | DT | denotes | the |
EnjuParser_T102 | 689-695 | NN | denotes | mutant |
EnjuParser_T103 | 696-699 | VBD | denotes | was |
EnjuParser_T104 | 700-713 | RB | denotes | enzymatically |
EnjuParser_T105 | 714-722 | JJ | denotes | inactive |
EnjuParser_T106 | 724-731 | NN | denotes | Western |
EnjuParser_T107 | 732-736 | NN | denotes | blot |
EnjuParser_T108 | 737-745 | NN | denotes | analysis |
EnjuParser_T109 | 746-758 | VBD | denotes | demonstrated |
EnjuParser_T110 | 759-763 | IN | denotes | that |
EnjuParser_T111 | 764-766 | IN | denotes | at |
EnjuParser_T112 | 767-773 | JJ | denotes | steady |
EnjuParser_T113 | 774-779 | NN | denotes | state |
EnjuParser_T114 | 780-783 | DT | denotes | the |
EnjuParser_T115 | 784-791 | NNS | denotes | amounts |
EnjuParser_T116 | 792-794 | IN | denotes | of |
EnjuParser_T117 | 795-804 | VBN | denotes | expressed |
EnjuParser_T118 | 805-816 | NN | denotes | p.Asn286Ser |
EnjuParser_T119 | 817-821 | NN | denotes | CLN2 |
EnjuParser_T120 | 822-826 | VBD | denotes | were |
EnjuParser_T121 | 827-834 | VBN | denotes | reduced |
EnjuParser_T122 | 835-843 | VBN | denotes | compared |
EnjuParser_T123 | 844-848 | IN | denotes | with |
EnjuParser_T124 | 849-858 | JJ | denotes | wild-type |
EnjuParser_T125 | 859-869 | VBG | denotes | expressing |
EnjuParser_T126 | 870-875 | NNS | denotes | cells |
EnjuParser_T127 | 877-880 | DT | denotes | The |
EnjuParser_T128 | 881-885 | NN | denotes | rate |
EnjuParser_T129 | 886-888 | IN | denotes | of |
EnjuParser_T130 | 889-898 | NN | denotes | synthesis |
EnjuParser_T131 | 899-902 | CC | denotes | and |
EnjuParser_T132 | 903-906 | DT | denotes | the |
EnjuParser_T133 | 907-914 | NN | denotes | sorting |
EnjuParser_T134 | 915-917 | IN | denotes | of |
EnjuParser_T135 | 918-921 | DT | denotes | the |
EnjuParser_T136 | 922-927 | RB | denotes | newly |
EnjuParser_T137 | 928-939 | VBN | denotes | synthesized |
EnjuParser_T138 | 940-951 | NN | denotes | p.Asn286Ser |
EnjuParser_T139 | 952-956 | NN | denotes | CLN2 |
EnjuParser_T140 | 957-959 | IN | denotes | in |
EnjuParser_T141 | 960-963 | DT | denotes | the |
EnjuParser_T142 | 964-969 | NNP | denotes | Golgi |
EnjuParser_T143 | 970-973 | VBD | denotes | was |
EnjuParser_T144 | 974-977 | RB | denotes | not |
EnjuParser_T145 | 978-986 | VBN | denotes | affected |
EnjuParser_T146 | 987-995 | VBN | denotes | compared |
EnjuParser_T147 | 996-1000 | IN | denotes | with |
EnjuParser_T148 | 1001-1010 | JJ | denotes | wild-type |
EnjuParser_T149 | 1011-1015 | NN | denotes | CLN2 |
EnjuParser_T150 | 1016-1023 | NN | denotes | protein |
EnjuParser_T151 | 1025-1028 | DT | denotes | The |
EnjuParser_T152 | 1029-1044 | JJ | denotes | electrophoretic |
EnjuParser_T153 | 1045-1053 | NN | denotes | mobility |
EnjuParser_T154 | 1054-1056 | IN | denotes | of |
EnjuParser_T155 | 1057-1060 | DT | denotes | the |
EnjuParser_T156 | 1061-1079 | VBN | denotes | immunoprecipitated |
EnjuParser_T157 | 1080-1086 | JJ | denotes | mutant |
EnjuParser_T158 | 1087-1098 | NN | denotes | p.Asn286Ser |
EnjuParser_T159 | 1099-1103 | NN | denotes | CLN2 |
EnjuParser_T160 | 1104-1107 | VBD | denotes | was |
EnjuParser_T161 | 1108-1117 | VBN | denotes | increased |
EnjuParser_T162 | 1118-1120 | IN | denotes | by |
EnjuParser_T163 | 1121-1134 | RB | denotes | approximately |
EnjuParser_T164 | 1135-1136 | CD | denotes | 2 |
EnjuParser_T165 | 1137-1140 | NN | denotes | kDa |
EnjuParser_T166 | 1141-1149 | VBN | denotes | compared |
EnjuParser_T167 | 1150-1154 | IN | denotes | with |
EnjuParser_T168 | 1155-1158 | DT | denotes | the |
EnjuParser_T169 | 1159-1168 | JJ | denotes | wild-type |
EnjuParser_T170 | 1169-1173 | NN | denotes | CLN2 |
EnjuParser_T171 | 1174-1181 | NN | denotes | protein |
EnjuParser_T172 | 1181-1182 | -COMMA- | denotes | , |
EnjuParser_T173 | 1183-1190 | IN | denotes | whereas |
EnjuParser_T174 | 1191-1206 | NN | denotes | deglycosylation |
EnjuParser_T175 | 1207-1210 | VBD | denotes | led |
EnjuParser_T176 | 1211-1213 | TO | denotes | to |
EnjuParser_T177 | 1214-1217 | DT | denotes | the |
EnjuParser_T178 | 1218-1228 | NN | denotes | generation |
EnjuParser_T179 | 1229-1231 | IN | denotes | of |
EnjuParser_T180 | 1232-1244 | NNS | denotes | polypeptides |
EnjuParser_T181 | 1245-1247 | IN | denotes | of |
EnjuParser_T182 | 1248-1251 | DT | denotes | the |
EnjuParser_T183 | 1252-1256 | JJ | denotes | same |
EnjuParser_T184 | 1257-1265 | JJ | denotes | apparent |
EnjuParser_T185 | 1266-1270 | NN | denotes | size |
EnjuParser_T186 | 1272-1275 | DT | denotes | The |
EnjuParser_T187 | 1276-1280 | NNS | denotes | data |
EnjuParser_T188 | 1281-1288 | VBP | denotes | suggest |
EnjuParser_T189 | 1289-1293 | IN | denotes | that |
EnjuParser_T190 | 1294-1300 | JJ | denotes | mutant |
EnjuParser_T191 | 1301-1312 | NN | denotes | p.Asn286Ser |
EnjuParser_T192 | 1313-1317 | NN | denotes | CLN2 |
EnjuParser_T193 | 1318-1323 | VBZ | denotes | lacks |
EnjuParser_T194 | 1324-1327 | CD | denotes | one |
EnjuParser_T195 | 1328-1343 | NN | denotes | oligosaccharide |
EnjuParser_T196 | 1344-1349 | NN | denotes | chain |
EnjuParser_T197 | 1350-1359 | VBG | denotes | resulting |
EnjuParser_T198 | 1360-1362 | IN | denotes | in |
EnjuParser_T199 | 1363-1372 | JJ | denotes | enzymatic |
EnjuParser_T200 | 1373-1385 | NN | denotes | inactivation |
EnjuParser_R0 | EnjuParser_T0 | EnjuParser_T1 | arg1Of | Mutation,of |
EnjuParser_R1 | EnjuParser_T5 | EnjuParser_T1 | arg2Of | residue,of |
EnjuParser_R2 | EnjuParser_T5 | EnjuParser_T2 | arg1Of | residue,the |
EnjuParser_R3 | EnjuParser_T5 | EnjuParser_T3 | arg2Of | residue,glycosylated |
EnjuParser_R4 | EnjuParser_T5 | EnjuParser_T4 | arg1Of | residue,asparagine |
EnjuParser_R5 | EnjuParser_T5 | EnjuParser_T6 | arg1Of | residue,286 |
EnjuParser_R6 | EnjuParser_T0 | EnjuParser_T7 | arg1Of | Mutation,in |
EnjuParser_R7 | EnjuParser_T10 | EnjuParser_T7 | arg2Of | protein,in |
EnjuParser_R8 | EnjuParser_T10 | EnjuParser_T8 | arg1Of | protein,human |
EnjuParser_R9 | EnjuParser_T10 | EnjuParser_T9 | arg1Of | protein,CLN2 |
EnjuParser_R10 | EnjuParser_T0 | EnjuParser_T11 | arg1Of | Mutation,results |
EnjuParser_R11 | EnjuParser_T11 | EnjuParser_T12 | arg1Of | results,in |
EnjuParser_R12 | EnjuParser_T13 | EnjuParser_T12 | arg2Of | loss,in |
EnjuParser_R13 | EnjuParser_T13 | EnjuParser_T14 | arg1Of | loss,of |
EnjuParser_R14 | EnjuParser_T16 | EnjuParser_T14 | arg2Of | activity,of |
EnjuParser_R15 | EnjuParser_T16 | EnjuParser_T15 | arg1Of | activity,enzymatic |
EnjuParser_R16 | EnjuParser_T21 | EnjuParser_T17 | arg1Of | lipofuscinosis,Late |
EnjuParser_R17 | EnjuParser_T21 | EnjuParser_T18 | arg1Of | lipofuscinosis,infantile |
EnjuParser_R18 | EnjuParser_T21 | EnjuParser_T19 | arg1Of | lipofuscinosis,neuronal |
EnjuParser_R19 | EnjuParser_T21 | EnjuParser_T20 | arg1Of | lipofuscinosis,ceroid |
EnjuParser_R20 | EnjuParser_T21 | EnjuParser_T22 | arg1Of | lipofuscinosis,( |
EnjuParser_R21 | EnjuParser_T23 | EnjuParser_T22 | arg2Of | LINCL,( |
EnjuParser_R22 | EnjuParser_T24 | EnjuParser_T22 | arg3Of | ),( |
EnjuParser_R23 | EnjuParser_T21 | EnjuParser_T25 | arg1Of | lipofuscinosis,is |
EnjuParser_R24 | EnjuParser_T26 | EnjuParser_T25 | arg2Of | caused,is |
EnjuParser_R25 | EnjuParser_T29 | EnjuParser_T26 | arg1Of | deficiency,caused |
EnjuParser_R26 | EnjuParser_T21 | EnjuParser_T26 | arg2Of | lipofuscinosis,caused |
EnjuParser_R27 | EnjuParser_T29 | EnjuParser_T27 | arg2Of | deficiency,by |
EnjuParser_R28 | EnjuParser_T29 | EnjuParser_T28 | arg1Of | deficiency,the |
EnjuParser_R29 | EnjuParser_T29 | EnjuParser_T30 | arg1Of | deficiency,of |
EnjuParser_R30 | EnjuParser_T34 | EnjuParser_T30 | arg2Of | peptidase-I,of |
EnjuParser_R31 | EnjuParser_T34 | EnjuParser_T31 | arg1Of | peptidase-I,the |
EnjuParser_R32 | EnjuParser_T34 | EnjuParser_T32 | arg1Of | peptidase-I,lysosomal |
EnjuParser_R33 | EnjuParser_T34 | EnjuParser_T33 | arg1Of | peptidase-I,tripeptidyl |
EnjuParser_R34 | EnjuParser_T37 | EnjuParser_T35 | arg1Of | CLN2,encoded |
EnjuParser_R35 | EnjuParser_T34 | EnjuParser_T35 | arg2Of | peptidase-I,encoded |
EnjuParser_R36 | EnjuParser_T37 | EnjuParser_T36 | arg2Of | CLN2,by |
EnjuParser_R37 | EnjuParser_T40 | EnjuParser_T39 | arg1Of | detected,previously |
EnjuParser_R38 | EnjuParser_T38 | EnjuParser_T40 | arg2Of | We,detected |
EnjuParser_R39 | EnjuParser_T40 | EnjuParser_T41 | arg1Of | detected,in |
EnjuParser_R40 | EnjuParser_T48 | EnjuParser_T41 | arg2Of | mutation,in |
EnjuParser_R41 | EnjuParser_T43 | EnjuParser_T42 | arg1Of | LINCL,two |
EnjuParser_R42 | EnjuParser_T48 | EnjuParser_T43 | arg1Of | mutation,LINCL |
EnjuParser_R43 | EnjuParser_T48 | EnjuParser_T44 | arg1Of | mutation,patients |
EnjuParser_R44 | EnjuParser_T48 | EnjuParser_T45 | arg1Of | mutation,a |
EnjuParser_R45 | EnjuParser_T48 | EnjuParser_T46 | arg1Of | mutation,homozygous |
EnjuParser_R46 | EnjuParser_T48 | EnjuParser_T47 | arg1Of | mutation,missense |
EnjuParser_R47 | EnjuParser_T48 | EnjuParser_T49 | arg1Of | mutation,"," |
EnjuParser_R48 | EnjuParser_T50 | EnjuParser_T49 | arg2Of | p.Asn286Ser,"," |
EnjuParser_R49 | EnjuParser_T48 | EnjuParser_T51 | arg1Of | mutation,"," |
EnjuParser_R50 | EnjuParser_T48 | EnjuParser_T52 | arg1Of | mutation,that |
EnjuParser_R51 | EnjuParser_T48 | EnjuParser_T53 | arg1Of | mutation,affects |
EnjuParser_R52 | EnjuParser_T57 | EnjuParser_T53 | arg2Of | site,affects |
EnjuParser_R53 | EnjuParser_T57 | EnjuParser_T54 | arg1Of | site,a |
EnjuParser_R54 | EnjuParser_T57 | EnjuParser_T55 | arg1Of | site,potential |
EnjuParser_R55 | EnjuParser_T57 | EnjuParser_T56 | arg1Of | site,N-glycosylation |
EnjuParser_R56 | EnjuParser_T58 | EnjuParser_T59 | arg1Of | We,introduced |
EnjuParser_R57 | EnjuParser_T62 | EnjuParser_T59 | arg2Of | mutation,introduced |
EnjuParser_R58 | EnjuParser_T62 | EnjuParser_T60 | arg1Of | mutation,the |
EnjuParser_R59 | EnjuParser_T62 | EnjuParser_T61 | arg1Of | mutation,p.Asn286Ser |
EnjuParser_R60 | EnjuParser_T62 | EnjuParser_T63 | arg1Of | mutation,into |
EnjuParser_R61 | EnjuParser_T67 | EnjuParser_T63 | arg2Of | cDNA,into |
EnjuParser_R62 | EnjuParser_T67 | EnjuParser_T64 | arg1Of | cDNA,the |
EnjuParser_R63 | EnjuParser_T67 | EnjuParser_T65 | arg1Of | cDNA,wild-type |
EnjuParser_R64 | EnjuParser_T67 | EnjuParser_T66 | arg1Of | cDNA,CLN2 |
EnjuParser_R65 | EnjuParser_T59 | EnjuParser_T68 | arg1Of | introduced,and |
EnjuParser_R66 | EnjuParser_T69 | EnjuParser_T68 | arg2Of | performed,and |
EnjuParser_R67 | EnjuParser_T58 | EnjuParser_T69 | arg1Of | We,performed |
EnjuParser_R68 | EnjuParser_T72 | EnjuParser_T69 | arg2Of | analysis,performed |
EnjuParser_R69 | EnjuParser_T72 | EnjuParser_T70 | arg1Of | analysis,transient |
EnjuParser_R70 | EnjuParser_T72 | EnjuParser_T71 | arg1Of | analysis,expression |
EnjuParser_R71 | EnjuParser_T74 | EnjuParser_T73 | arg1Of | determine,to |
EnjuParser_R72 | EnjuParser_T69 | EnjuParser_T73 | modOf | performed,to |
EnjuParser_R73 | EnjuParser_T58 | EnjuParser_T74 | arg1Of | We,determine |
EnjuParser_R74 | EnjuParser_T76 | EnjuParser_T74 | arg2Of | effect,determine |
EnjuParser_R75 | EnjuParser_T76 | EnjuParser_T75 | arg1Of | effect,the |
EnjuParser_R76 | EnjuParser_T74 | EnjuParser_T77 | arg1Of | determine,on |
EnjuParser_R77 | EnjuParser_T85 | EnjuParser_T77 | arg2Of | and,on |
EnjuParser_R78 | EnjuParser_T80 | EnjuParser_T78 | arg1Of | activity,the |
EnjuParser_R79 | EnjuParser_T80 | EnjuParser_T79 | arg1Of | activity,catalytic |
EnjuParser_R80 | EnjuParser_T80 | EnjuParser_T81 | arg1Of | activity,"," |
EnjuParser_R81 | EnjuParser_T83 | EnjuParser_T81 | arg2Of | targeting,"," |
EnjuParser_R82 | EnjuParser_T83 | EnjuParser_T82 | arg1Of | targeting,intracellular |
EnjuParser_R83 | EnjuParser_T85 | EnjuParser_T84 | arg1Of | and,"," |
EnjuParser_R84 | EnjuParser_T80 | EnjuParser_T85 | arg1Of | activity,and |
EnjuParser_R85 | EnjuParser_T86 | EnjuParser_T85 | arg2Of | glycosylation,and |
EnjuParser_R86 | EnjuParser_T86 | EnjuParser_T87 | arg1Of | glycosylation,of |
EnjuParser_R87 | EnjuParser_T90 | EnjuParser_T87 | arg2Of | protein,of |
EnjuParser_R88 | EnjuParser_T90 | EnjuParser_T88 | arg1Of | protein,the |
EnjuParser_R89 | EnjuParser_T90 | EnjuParser_T89 | arg1Of | protein,CLN2 |
EnjuParser_R90 | EnjuParser_T91 | EnjuParser_T92 | arg1Of | Expression,of |
EnjuParser_R91 | EnjuParser_T95 | EnjuParser_T92 | arg2Of | CLN2,of |
EnjuParser_R92 | EnjuParser_T95 | EnjuParser_T93 | arg1Of | CLN2,mutant |
EnjuParser_R93 | EnjuParser_T95 | EnjuParser_T94 | arg1Of | CLN2,p.Asn286Ser |
EnjuParser_R94 | EnjuParser_T91 | EnjuParser_T96 | arg1Of | Expression,in |
EnjuParser_R95 | EnjuParser_T98 | EnjuParser_T96 | arg2Of | cells,in |
EnjuParser_R96 | EnjuParser_T98 | EnjuParser_T97 | arg1Of | cells,HEK293 |
EnjuParser_R97 | EnjuParser_T91 | EnjuParser_T99 | arg1Of | Expression,revealed |
EnjuParser_R98 | EnjuParser_T103 | EnjuParser_T99 | arg2Of | was,revealed |
EnjuParser_R99 | EnjuParser_T103 | EnjuParser_T100 | arg1Of | was,that |
EnjuParser_R100 | EnjuParser_T102 | EnjuParser_T101 | arg1Of | mutant,the |
EnjuParser_R101 | EnjuParser_T102 | EnjuParser_T103 | arg1Of | mutant,was |
EnjuParser_R102 | EnjuParser_T105 | EnjuParser_T103 | arg2Of | inactive,was |
EnjuParser_R103 | EnjuParser_T105 | EnjuParser_T104 | arg1Of | inactive,enzymatically |
EnjuParser_R104 | EnjuParser_T102 | EnjuParser_T105 | arg1Of | mutant,inactive |
EnjuParser_R105 | EnjuParser_T108 | EnjuParser_T106 | arg1Of | analysis,Western |
EnjuParser_R106 | EnjuParser_T108 | EnjuParser_T107 | arg1Of | analysis,blot |
EnjuParser_R107 | EnjuParser_T108 | EnjuParser_T109 | arg1Of | analysis,demonstrated |
EnjuParser_R108 | EnjuParser_T121 | EnjuParser_T109 | arg2Of | reduced,demonstrated |
EnjuParser_R109 | EnjuParser_T121 | EnjuParser_T110 | arg1Of | reduced,that |
EnjuParser_R110 | EnjuParser_T121 | EnjuParser_T111 | arg1Of | reduced,at |
EnjuParser_R111 | EnjuParser_T113 | EnjuParser_T111 | arg2Of | state,at |
EnjuParser_R112 | EnjuParser_T113 | EnjuParser_T112 | arg1Of | state,steady |
EnjuParser_R113 | EnjuParser_T115 | EnjuParser_T114 | arg1Of | amounts,the |
EnjuParser_R114 | EnjuParser_T115 | EnjuParser_T116 | arg1Of | amounts,of |
EnjuParser_R115 | EnjuParser_T119 | EnjuParser_T116 | arg2Of | CLN2,of |
EnjuParser_R116 | EnjuParser_T119 | EnjuParser_T117 | arg2Of | CLN2,expressed |
EnjuParser_R117 | EnjuParser_T119 | EnjuParser_T118 | arg1Of | CLN2,p.Asn286Ser |
EnjuParser_R118 | EnjuParser_T115 | EnjuParser_T120 | arg1Of | amounts,were |
EnjuParser_R119 | EnjuParser_T121 | EnjuParser_T120 | arg2Of | reduced,were |
EnjuParser_R120 | EnjuParser_T115 | EnjuParser_T121 | arg2Of | amounts,reduced |
EnjuParser_R121 | EnjuParser_T121 | EnjuParser_T122 | arg1Of | reduced,compared |
EnjuParser_R122 | EnjuParser_T123 | EnjuParser_T122 | arg2Of | with,compared |
EnjuParser_R123 | EnjuParser_T126 | EnjuParser_T123 | arg2Of | cells,with |
EnjuParser_R124 | EnjuParser_T126 | EnjuParser_T124 | arg1Of | cells,wild-type |
EnjuParser_R125 | EnjuParser_T126 | EnjuParser_T125 | arg1Of | cells,expressing |
EnjuParser_R126 | EnjuParser_T128 | EnjuParser_T127 | arg1Of | rate,The |
EnjuParser_R127 | EnjuParser_T128 | EnjuParser_T129 | arg1Of | rate,of |
EnjuParser_R128 | EnjuParser_T130 | EnjuParser_T129 | arg2Of | synthesis,of |
EnjuParser_R129 | EnjuParser_T128 | EnjuParser_T131 | arg1Of | rate,and |
EnjuParser_R130 | EnjuParser_T133 | EnjuParser_T131 | arg2Of | sorting,and |
EnjuParser_R131 | EnjuParser_T133 | EnjuParser_T132 | arg1Of | sorting,the |
EnjuParser_R132 | EnjuParser_T133 | EnjuParser_T134 | arg1Of | sorting,of |
EnjuParser_R133 | EnjuParser_T139 | EnjuParser_T134 | arg2Of | CLN2,of |
EnjuParser_R134 | EnjuParser_T139 | EnjuParser_T135 | arg1Of | CLN2,the |
EnjuParser_R135 | EnjuParser_T137 | EnjuParser_T136 | arg1Of | synthesized,newly |
EnjuParser_R136 | EnjuParser_T139 | EnjuParser_T137 | arg1Of | CLN2,synthesized |
EnjuParser_R137 | EnjuParser_T139 | EnjuParser_T138 | arg1Of | CLN2,p.Asn286Ser |
EnjuParser_R138 | EnjuParser_T139 | EnjuParser_T140 | arg1Of | CLN2,in |
EnjuParser_R139 | EnjuParser_T142 | EnjuParser_T140 | arg2Of | Golgi,in |
EnjuParser_R140 | EnjuParser_T142 | EnjuParser_T141 | arg1Of | Golgi,the |
EnjuParser_R141 | EnjuParser_T131 | EnjuParser_T143 | arg1Of | and,was |
EnjuParser_R142 | EnjuParser_T145 | EnjuParser_T143 | arg2Of | affected,was |
EnjuParser_R143 | EnjuParser_T145 | EnjuParser_T144 | arg1Of | affected,not |
EnjuParser_R144 | EnjuParser_T131 | EnjuParser_T145 | arg2Of | and,affected |
EnjuParser_R145 | EnjuParser_T145 | EnjuParser_T146 | arg1Of | affected,compared |
EnjuParser_R146 | EnjuParser_T147 | EnjuParser_T146 | arg2Of | with,compared |
EnjuParser_R147 | EnjuParser_T150 | EnjuParser_T147 | arg2Of | protein,with |
EnjuParser_R148 | EnjuParser_T150 | EnjuParser_T148 | arg1Of | protein,wild-type |
EnjuParser_R149 | EnjuParser_T150 | EnjuParser_T149 | arg1Of | protein,CLN2 |
EnjuParser_R150 | EnjuParser_T153 | EnjuParser_T151 | arg1Of | mobility,The |
EnjuParser_R151 | EnjuParser_T153 | EnjuParser_T152 | arg1Of | mobility,electrophoretic |
EnjuParser_R152 | EnjuParser_T153 | EnjuParser_T154 | arg1Of | mobility,of |
EnjuParser_R153 | EnjuParser_T159 | EnjuParser_T154 | arg2Of | CLN2,of |
EnjuParser_R154 | EnjuParser_T159 | EnjuParser_T155 | arg1Of | CLN2,the |
EnjuParser_R155 | EnjuParser_T159 | EnjuParser_T156 | arg2Of | CLN2,immunoprecipitated |
EnjuParser_R156 | EnjuParser_T159 | EnjuParser_T157 | arg1Of | CLN2,mutant |
EnjuParser_R157 | EnjuParser_T159 | EnjuParser_T158 | arg1Of | CLN2,p.Asn286Ser |
EnjuParser_R158 | EnjuParser_T153 | EnjuParser_T160 | arg1Of | mobility,was |
EnjuParser_R159 | EnjuParser_T161 | EnjuParser_T160 | arg2Of | increased,was |
EnjuParser_R160 | EnjuParser_T153 | EnjuParser_T161 | arg2Of | mobility,increased |
EnjuParser_R161 | EnjuParser_T161 | EnjuParser_T162 | arg1Of | increased,by |
EnjuParser_R162 | EnjuParser_T165 | EnjuParser_T162 | arg2Of | kDa,by |
EnjuParser_R163 | EnjuParser_T164 | EnjuParser_T163 | arg1Of | 2,approximately |
EnjuParser_R164 | EnjuParser_T165 | EnjuParser_T164 | arg1Of | kDa,2 |
EnjuParser_R165 | EnjuParser_T161 | EnjuParser_T166 | arg1Of | increased,compared |
EnjuParser_R166 | EnjuParser_T167 | EnjuParser_T166 | arg2Of | with,compared |
EnjuParser_R167 | EnjuParser_T171 | EnjuParser_T167 | arg2Of | protein,with |
EnjuParser_R168 | EnjuParser_T171 | EnjuParser_T168 | arg1Of | protein,the |
EnjuParser_R169 | EnjuParser_T171 | EnjuParser_T169 | arg1Of | protein,wild-type |
EnjuParser_R170 | EnjuParser_T171 | EnjuParser_T170 | arg1Of | protein,CLN2 |
EnjuParser_R171 | EnjuParser_T173 | EnjuParser_T172 | arg1Of | whereas,"," |
EnjuParser_R172 | EnjuParser_T161 | EnjuParser_T173 | arg1Of | increased,whereas |
EnjuParser_R173 | EnjuParser_T175 | EnjuParser_T173 | arg2Of | led,whereas |
EnjuParser_R174 | EnjuParser_T174 | EnjuParser_T175 | arg1Of | deglycosylation,led |
EnjuParser_R175 | EnjuParser_T175 | EnjuParser_T176 | arg1Of | led,to |
EnjuParser_R176 | EnjuParser_T178 | EnjuParser_T176 | arg2Of | generation,to |
EnjuParser_R177 | EnjuParser_T178 | EnjuParser_T177 | arg1Of | generation,the |
EnjuParser_R178 | EnjuParser_T178 | EnjuParser_T179 | arg1Of | generation,of |
EnjuParser_R179 | EnjuParser_T180 | EnjuParser_T179 | arg2Of | polypeptides,of |
EnjuParser_R180 | EnjuParser_T180 | EnjuParser_T181 | arg1Of | polypeptides,of |
EnjuParser_R181 | EnjuParser_T185 | EnjuParser_T181 | arg2Of | size,of |
EnjuParser_R182 | EnjuParser_T185 | EnjuParser_T182 | arg1Of | size,the |
EnjuParser_R183 | EnjuParser_T185 | EnjuParser_T183 | arg1Of | size,same |
EnjuParser_R184 | EnjuParser_T185 | EnjuParser_T184 | arg1Of | size,apparent |
EnjuParser_R185 | EnjuParser_T187 | EnjuParser_T186 | arg1Of | data,The |
EnjuParser_R186 | EnjuParser_T187 | EnjuParser_T188 | arg1Of | data,suggest |
EnjuParser_R187 | EnjuParser_T193 | EnjuParser_T188 | arg2Of | lacks,suggest |
EnjuParser_R188 | EnjuParser_T193 | EnjuParser_T189 | arg1Of | lacks,that |
EnjuParser_R189 | EnjuParser_T192 | EnjuParser_T190 | arg1Of | CLN2,mutant |
EnjuParser_R190 | EnjuParser_T192 | EnjuParser_T191 | arg1Of | CLN2,p.Asn286Ser |
EnjuParser_R191 | EnjuParser_T192 | EnjuParser_T193 | arg1Of | CLN2,lacks |
EnjuParser_R192 | EnjuParser_T196 | EnjuParser_T193 | arg2Of | chain,lacks |
EnjuParser_R193 | EnjuParser_T196 | EnjuParser_T194 | arg1Of | chain,one |
EnjuParser_R194 | EnjuParser_T196 | EnjuParser_T195 | arg1Of | chain,oligosaccharide |
EnjuParser_R195 | EnjuParser_T196 | EnjuParser_T197 | arg1Of | chain,resulting |
EnjuParser_R196 | EnjuParser_T197 | EnjuParser_T198 | arg1Of | resulting,in |
EnjuParser_R197 | EnjuParser_T200 | EnjuParser_T198 | arg2Of | inactivation,in |
EnjuParser_R198 | EnjuParser_T200 | EnjuParser_T199 | arg1Of | inactivation,enzymatic |
performance-test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-UBERON-AE-B_T1 | 128-136 | http://purl.obolibrary.org/obo/UBERON_2000602 | denotes | neuronal |
DisGeNET
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T0 | 212-235 | gene:1200 | denotes | tripeptidyl peptidase-I |
T1 | 113-158 | disease:C0022340 | denotes | Late infantile neuronal ceroid lipofuscinosis |
T2 | 212-235 | gene:1200 | denotes | tripeptidyl peptidase-I |
T3 | 160-165 | disease:C0022340 | denotes | LINCL |
T4 | 247-251 | gene:1200 | denotes | CLN2 |
T5 | 113-158 | disease:C0022340 | denotes | Late infantile neuronal ceroid lipofuscinosis |
T6 | 247-251 | gene:1200 | denotes | CLN2 |
T7 | 160-165 | disease:C0022340 | denotes | LINCL |
R1 | T0 | T1 | associated_with | tripeptidyl peptidase-I,Late infantile neuronal ceroid lipofuscinosis |
R2 | T2 | T3 | associated_with | tripeptidyl peptidase-I,LINCL |
R3 | T4 | T5 | associated_with | CLN2,Late infantile neuronal ceroid lipofuscinosis |
R4 | T6 | T7 | associated_with | CLN2,LINCL |