PubMed:14707489
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 201-208 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T2 | 414-421 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 201-208 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T2 | 414-421 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-123 | Sentence | denotes | Synthesis of a targeting drug for antifibrosis of liver; a conjugate for delivering glycyrrhetin to hepatic stellate cells. |
| TextSentencer_T2 | 124-354 | Sentence | denotes | The neoglycoproteins that consist of human serum albumin (HSA) modified with mannose 6-phosphate ([M6P]x-HSA) were synthesized, and they showed high binding property to hepatic stellate cells (HSC) by immunohistochemical analysis. |
| TextSentencer_T3 | 355-481 | Sentence | denotes | In addition, an increased substitution (X) of 6-phosphated mannose (M6P) was associated with an increased accumulation in HSC. |
| TextSentencer_T4 | 482-543 | Sentence | denotes | So the [M6P]x-HSA might be a carrier to deliver drugs to HSC. |
| TextSentencer_T5 | 544-620 | Sentence | denotes | The antifibrotic drug, glycyrrhetin, was chosen to conjugate to M6P(26)-HSA. |
| TextSentencer_T6 | 621-731 | Sentence | denotes | The result suggests there were 6 approximately 7 glycyrrhetin molecules having been conjugated to the carrier. |
| TextSentencer_T7 | 732-821 | Sentence | denotes | Targeting glycyrrhetin to HSC might reduce its adverse affects and increase the efficacy. |
| T1 | 0-123 | Sentence | denotes | Synthesis of a targeting drug for antifibrosis of liver; a conjugate for delivering glycyrrhetin to hepatic stellate cells. |
| T2 | 124-354 | Sentence | denotes | The neoglycoproteins that consist of human serum albumin (HSA) modified with mannose 6-phosphate ([M6P]x-HSA) were synthesized, and they showed high binding property to hepatic stellate cells (HSC) by immunohistochemical analysis. |
| T3 | 355-481 | Sentence | denotes | In addition, an increased substitution (X) of 6-phosphated mannose (M6P) was associated with an increased accumulation in HSC. |
| T4 | 482-543 | Sentence | denotes | So the [M6P]x-HSA might be a carrier to deliver drugs to HSC. |
| T5 | 544-620 | Sentence | denotes | The antifibrotic drug, glycyrrhetin, was chosen to conjugate to M6P(26)-HSA. |
| T6 | 621-731 | Sentence | denotes | The result suggests there were 6 approximately 7 glycyrrhetin molecules having been conjugated to the carrier. |
| T7 | 732-821 | Sentence | denotes | Targeting glycyrrhetin to HSC might reduce its adverse affects and increase the efficacy. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-55 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 182-185 | Disease | denotes | HSA | http://purl.obolibrary.org/obo/MONDO_0011848 |
| T2 | 229-232 | Disease | denotes | HSA | http://purl.obolibrary.org/obo/MONDO_0011848 |
| T3 | 496-499 | Disease | denotes | HSA | http://purl.obolibrary.org/obo/MONDO_0011848 |
| T4 | 616-619 | Disease | denotes | HSA | http://purl.obolibrary.org/obo/MONDO_0011848 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 50-55 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 161-166 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 50-55 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T2 | 100-122 | Body_part | denotes | hepatic stellate cells | http://purl.obolibrary.org/obo/CL_0000632 |
| T3 | 293-315 | Body_part | denotes | hepatic stellate cells | http://purl.obolibrary.org/obo/CL_0000632 |
| T4 | 317-320 | Body_part | denotes | HSC | http://purl.obolibrary.org/obo/CL_0000632 |
| T5 | 477-480 | Body_part | denotes | HSC | http://purl.obolibrary.org/obo/CL_0000632 |
| T6 | 539-542 | Body_part | denotes | HSC | http://purl.obolibrary.org/obo/CL_0000632 |
| T7 | 758-761 | Body_part | denotes | HSC | http://purl.obolibrary.org/obo/CL_0000632 |
Glycosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 100-122 | Cell | denotes | hepatic stellate cells | http://purl.obolibrary.org/obo/CL:0000632 |
| T2 | 293-315 | Cell | denotes | hepatic stellate cells | http://purl.obolibrary.org/obo/CL:0000632 |
| T3 | 317-320 | Cell | denotes | HSC | http://purl.obolibrary.org/obo/CL:0000632 |
| T4 | 477-480 | Cell | denotes | HSC | http://purl.obolibrary.org/obo/CL:0000632 |
| T5 | 539-542 | Cell | denotes | HSC | http://purl.obolibrary.org/obo/CL:0000632 |
| T6 | 758-761 | Cell | denotes | HSC | http://purl.obolibrary.org/obo/CL:0000632 |