PubMed:14707487
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-9 | Glycan_Motif | denotes | Sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T4 | 283-292 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T7 | 345-354 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T10 | 648-657 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T13 | 831-840 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T16 | 1002-1011 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
| T19 | 1430-1439 | Glycan_Motif | denotes | sulfatide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-9 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | Sulfatide |
| T2 | 0-9 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | Sulfatide |
| T3 | 0-9 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | Sulfatide |
| T4 | 283-292 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T5 | 283-292 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T6 | 283-292 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
| T7 | 345-354 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T8 | 345-354 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T9 | 345-354 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
| T10 | 648-657 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T11 | 648-657 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T12 | 648-657 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
| T13 | 831-840 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T14 | 831-840 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T15 | 831-840 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
| T16 | 1002-1011 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T17 | 1002-1011 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T18 | 1002-1011 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
| T19 | 1430-1439 | https://glytoucan.org/Structures/Glycans/G40843KY | denotes | sulfatide |
| T20 | 1430-1439 | https://glytoucan.org/Structures/Glycans/G72548RZ | denotes | sulfatide |
| T21 | 1430-1439 | https://glytoucan.org/Structures/Glycans/G95090DW | denotes | sulfatide |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-103 | Sentence | denotes | Sulfatide is associated with insulin granules and located to microdomains of a cultured beta cell line. |
| TextSentencer_T2 | 104-329 | Sentence | denotes | Previous studies using pancreas from various mammals and freshly isolated islets from rat pancreas have provided evidence supporting possible involvement of the glycosphingolipid sulfatide in insulin processing and secretion. |
| TextSentencer_T3 | 330-567 | Sentence | denotes | In this study, sulfatide expression and metabolism in the beta cell line RINr1046-38 (RIN-38), commonly used as a model for beta cell functional studies, were investigated and compared with previous findings from freshly isolated islets. |
| TextSentencer_T4 | 568-752 | Sentence | denotes | RIN-38 cells expressed similar amounts (2.7 +/- 1.1 nmol/mg protein, n = 19) of sulfatide as isolated rat islets and also followed the same metabolic pathway, mainly through recycling. |
| TextSentencer_T5 | 753-906 | Sentence | denotes | Moreover, in agreement with findings in isolated islets, the major species of sulfatide isolated from RIN-38 cells contained C16:0 and C24:0 fatty acids. |
| TextSentencer_T6 | 907-1132 | Sentence | denotes | By applying subcellular isolations and electron microscopy and immunocytochemistry techniques, sulfatide was shown to be located to the secretory granules, the plasma membrane and enriched in detergent insoluble microdomains. |
| TextSentencer_T7 | 1133-1245 | Sentence | denotes | In the electron microscopy studies, Sulph I staining was also associated with mitochondria and villi structures. |
| TextSentencer_T8 | 1246-1499 | Sentence | denotes | In conclusion, RIN-38 cells might be an appropriate model, as a complement to isolated islets where the amount of material often limits the experiments, to further explore the role of sulfatide in insulin secretion and signal transduction of beta cells. |
| T1 | 0-103 | Sentence | denotes | Sulfatide is associated with insulin granules and located to microdomains of a cultured beta cell line. |
| T2 | 104-329 | Sentence | denotes | Previous studies using pancreas from various mammals and freshly isolated islets from rat pancreas have provided evidence supporting possible involvement of the glycosphingolipid sulfatide in insulin processing and secretion. |
| T3 | 330-567 | Sentence | denotes | In this study, sulfatide expression and metabolism in the beta cell line RINr1046-38 (RIN-38), commonly used as a model for beta cell functional studies, were investigated and compared with previous findings from freshly isolated islets. |
| T4 | 568-752 | Sentence | denotes | RIN-38 cells expressed similar amounts (2.7 +/- 1.1 nmol/mg protein, n = 19) of sulfatide as isolated rat islets and also followed the same metabolic pathway, mainly through recycling. |
| T5 | 753-906 | Sentence | denotes | Moreover, in agreement with findings in isolated islets, the major species of sulfatide isolated from RIN-38 cells contained C16:0 and C24:0 fatty acids. |
| T6 | 907-1132 | Sentence | denotes | By applying subcellular isolations and electron microscopy and immunocytochemistry techniques, sulfatide was shown to be located to the secretory granules, the plasma membrane and enriched in detergent insoluble microdomains. |
| T7 | 1133-1245 | Sentence | denotes | In the electron microscopy studies, Sulph I staining was also associated with mitochondria and villi structures. |
| T8 | 1246-1499 | Sentence | denotes | In conclusion, RIN-38 cells might be an appropriate model, as a complement to isolated islets where the amount of material often limits the experiments, to further explore the role of sulfatide in insulin secretion and signal transduction of beta cells. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 127-135 | http://purl.obolibrary.org/obo/MAT_0000075 | denotes | pancreas |
| T2 | 194-202 | http://purl.obolibrary.org/obo/MAT_0000075 | denotes | pancreas |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 127-135 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T2 | 194-202 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 127-135 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T2 | 194-202 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 190-193 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 670-673 | OrganismTaxon | denotes | rat | 10114|10116 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 88-97 | Body_part | denotes | beta cell | http://purl.obolibrary.org/obo/CL_0000169 |
| T2 | 127-135 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T4 | 194-202 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T6 | 388-397 | Body_part | denotes | beta cell | http://purl.obolibrary.org/obo/CL_0000169 |
| T7 | 454-463 | Body_part | denotes | beta cell | http://purl.obolibrary.org/obo/CL_0000169 |
| T8 | 1043-1061 | Body_part | denotes | secretory granules | http://purl.obolibrary.org/obo/GO_0030141 |
| T9 | 1067-1082 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
| T10 | 1488-1498 | Body_part | denotes | beta cells | http://purl.obolibrary.org/obo/CL_0000169 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 88-97 | Cell | denotes | beta cell | http://purl.obolibrary.org/obo/CL:0000169|http://purl.obolibrary.org/obo/CL:0000639 |
| T3 | 388-397 | Cell | denotes | beta cell | http://purl.obolibrary.org/obo/CL:0000169|http://purl.obolibrary.org/obo/CL:0000639 |
| T5 | 454-463 | Cell | denotes | beta cell | http://purl.obolibrary.org/obo/CL:0000169|http://purl.obolibrary.org/obo/CL:0000639 |
| T7 | 1488-1498 | Cell | denotes | beta cells | http://purl.obolibrary.org/obo/CL:0000169|http://purl.obolibrary.org/obo/CL:0000639 |